• Title/Summary/Keyword: D.N.A

Search Result 10,509, Processing Time 0.048 seconds

Antimicrobial Activity of N-Acetyl-Phenylalanine Produced from Streptomyces sp. G91353 (Streptomyces sp. G91353이 생산하는 N-Acetyl-Phenylalanine의 항균활성)

  • Kwon, Oh-Sung;Park, Hae-Ryong;Yun, Bong-Sik;Hwang, Ji-Hwan;Lee, Jae-Chan;Park, Dong-Jin;Kim, Chang-Jin
    • Microbiology and Biotechnology Letters
    • /
    • v.34 no.4
    • /
    • pp.306-310
    • /
    • 2006
  • For screening of the compounds exhibiting antimicrobial activities against the D-alanyl-D-alanine of Gram positive bacteria, approximately 2,500 actinomycetes isolated from soil were examined far antimicrobial activity. In consequence, we recently isolated the Streptomyces sp. G91353 strain produced an active compound, A91353, that inhibits the growth of Gram positive bacteria. A91353 was identified as N-acetyl-phenylalanine by various spectroscopic methods. The minimum inhibitory concentration (MIC) values of N-acetyl-phenylalanine on Gram positive bacteria such as Streptococcus pyogenes 308A, Streptococcus pyogenes 77A were determined as $50{\mu}g/ml$, respectively, but did not effect on Gram negative strains. These results indicate that N-acetyl-phenylalanine have an antimicrobial activity, which may be caused by the disturbance of D-alanyl-D-alanine synthesis.

ON COMBINATORICS OF KONHAUSER POLYNOMIALS

  • Kim, Dong-Su
    • Journal of the Korean Mathematical Society
    • /
    • v.33 no.2
    • /
    • pp.423-438
    • /
    • 1996
  • Let L be a linear functional on the vector space of polynomials in x. Let $\omega(x)$ be a polynomial in x of degree d, for some positive integer d. We consider two sets of polynomials, ${R_n (x)}_{n \geq 0}, {S_n(x)}_{n \geq 0}$, such that $R_n(x)$ is a polynomial in x of degree n and $S_n(x)$ is a polynomial in $\omega(x)$ of degree n. (So $S_n(x)$ is a polynomial in x of degree dn.)

  • PDF

SOME RELATIONS BETWEEN FUNCTION SPACES ON R$^n$

  • Shin, Seung-Hyun
    • The Pure and Applied Mathematics
    • /
    • v.2 no.1
    • /
    • pp.31-34
    • /
    • 1995
  • Let R$^n$be n-th Euclidean space. Let be the n-th spere embeded as a subspace in R$\^$n+1/ centered at the origin. In this paper, we are going to consider the function space F = {f│f : S$^n$\longrightarrow S$^n$} metrized by as follow D(f,g)=d(f($\chi$), g($\chi$)) where f, g $\in$ F and d is the metric in S$^n$. Finally we want to find certain relation these spaces.(omitted)

  • PDF

ON ALMOST PSEUDO-VALUATION DOMAINS, II

  • Chang, Gyu Whan
    • Korean Journal of Mathematics
    • /
    • v.19 no.4
    • /
    • pp.343-349
    • /
    • 2011
  • Let D be an integral domain, $D^w$ be the $w$-integral closure of D, X be an indeterminate over D, and $N_v=\{f{\in}D[X]{\mid}c(f)_v=D\}$. In this paper, we introduce the concept of $t$-locally APVD. We show that D is a $t$-locally APVD and a UMT-domain if and only if D is a $t$-locally APVD and $D^w$ is a $PvMD$, if and only if D[X] is a $t$-locally APVD, if and only if $D[X]_{N_v}$ is a locally APVD.

THE NUMBER OF REPRESENTATIONS OF A POSITIVE INTEGER BY TRIANGULAR, SQUARE AND DECAGONAL NUMBERS

  • Isnaini, Uha;Melham, Ray;Toh, Pee Choon
    • Bulletin of the Korean Mathematical Society
    • /
    • v.56 no.5
    • /
    • pp.1143-1157
    • /
    • 2019
  • Let $T_aD_b(n)$ and $T_aD^{\prime}_b(n)$ denote respectively the number of representations of a positive integer n by $a(x^2-x)/2+b(4y^2-3y)$ and $a(x^2-x)/2+b(4y^2-y)$. Similarly, let $S_aD_b(n)$ and $S_aD^{\prime}_b(n)$ denote respectively the number of representations of n by $ax^2+b(4y^2-3y)$ and $ax^2+b(4y^2-y)$. In this paper, we prove 162 formulas for these functions.

UPPERS TO ZERO IN POLYNOMIAL RINGS WHICH ARE MAXIMAL IDEALS

  • Chang, Gyu Whan
    • Bulletin of the Korean Mathematical Society
    • /
    • v.52 no.2
    • /
    • pp.525-530
    • /
    • 2015
  • Let D be an integrally closed domain with quotient field K, X be an indeterminate over D, $f=a_0+a_1X+{\cdots}+a_nX^n{\in}D[X]$ be irreducible in K[X], and $Q_f=fK[X]{\cap}D[X]$. In this paper, we show that $Q_f$ is a maximal ideal of D[X] if and only if $(\frac{a_1}{a_0},{\cdots},\frac{a_n}{a_0}){\subseteq}P$ for all nonzero prime ideals P of D; in this case, $Q_f=\frac{1}{a_0}fD[X]$. As a corollary, we have that if D is a Krull domain, then D has infinitely many height-one prime ideals if and only if each maximal ideal of D[X] has height ${\geq}2$.

Hepatoprotective Effects of Oyster Hydrolysate on Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Injury in Mice (Lipopolysaccharide/D-Galactosamine에 의해 유도된 급성 간 손상 생쥐모델에서 굴가수분해물의 간 보호 효과)

  • Ryu, Ji Hyeon;Kim, Eun-Jin;Xie, Chengliang;Nyiramana, Marie Merci;Siregar, Adrian S.;Park, Si-Hyang;Cho, Soo Buem;Song, Dae Hyun;Kim, Nam-Gil;Choi, Yeung Joon;Kang, Sang Soo;Kang, Dawon
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.46 no.6
    • /
    • pp.659-670
    • /
    • 2017
  • Oxidative stress and inflammation are key factors responsible for progression of liver injury. A variety of functions of oyster hydrolysate (OH) are affected by their antioxidant and anti-inflammatory activities. However, little is known regarding the effects of OH on a liver injury model. This study was performed to evaluate the effects of OH on acute liver injury induced by lipopolysaccharide/D-galactosamine (LPS/D-GalN) in mice. Experimental groups were divided into six groups as follows (each group, n=10): control (saline), LPS/D-GalN, LPS/D-GalN+OH (100 mg/kg), LPS/D-GalN+OH (200 mg/kg), LPS/D-GalN+OH (400 mg/kg), and LPS/D-GalN+silymarin (25 mg/kg, positive control). The experimental acute liver injury model was induced with LPS ($1{\mu}g/kg$) and D-GalN (400 mg/kg). We first analyzed antioxidant and anti-inflammatory activities in OH. OH showed high DPPH and ABTS radical scavenging activities and reduced ROS generation in Chang cells in a dose-dependent manner. In addition, OH showed anti-inflammatory activities, such as inhibition of cyclooxygenase-2 and 5-lipooxygenase. Treatment with OH down-regulated tumor necrosis factor $(TNF)-{\alpha}$, interleukin (IL)-6, and $IL-1{\alpha}$ expression levels in LPS-stimulated RAW264.7 cells. OH significantly reduced LPS/D-GalN-induced increases in the concentrations of alanine transaminase and aspartate aminotransferase in serum. In the LPS/D-GalN group, liver tissues exhibited apoptosis of hepatocytes with hemorrhages. These pathological alterations were ameliorated by OH treatment. Consistently, hepatic catalase activity was low in the LPS/D-GalN group compared to the control group, and catalase activity was significantly restored by OH treatment (P<0.05). Furthermore, OH markedly reduced the LPS/D-GalN-induced increase in $TNF-{\alpha}$, $IL-1{\beta}$, and IL-6 levels in liver tissue. Taken together, these results show that OH has hepatoprotective effects on LPS/D-GalN-induced acute liver injury via inhibition of oxidative stress and inflammation, suggesting that OH could be used as a health functional food and potential therapeutic agent for acute liver injury.

A X-band 40W AlGaN/GaN Power Amplifier MMIC for Radar Applications (레이더 응용을 위한 X-대역 40W AlGaN/GaN 전력 증폭기 MMIC)

  • Byeong-Ok, Lim;Joo-Seoc, Go;Keun-Kwan, Ryu;Sung-Chan, Kim
    • Journal of IKEEE
    • /
    • v.26 no.4
    • /
    • pp.722-727
    • /
    • 2022
  • In this paper, we present the design and characterization of a power amplifier (PA) monolithic microwave integrated circuit (MMIC) in the X-band. The device is designed using a 0.25 ㎛ gate length AlGaN/GaN high electron mobility transistor (HEMT) on SiC process. The developed X-band AlGaN/GaN power amplifier MMIC achieves small signal gain of over 21.6 dB and output power more than 46.11 dBm (40.83 W) in the entire band of 9 GHz to 10 GHz. Its power added efficiency (PAE) is 43.09% ~ 44.47% and the chip dimensions are 3.6 mm × 4.3 mm. The generated output power density is 2.69 W/mm2. It seems that the developed AlGaN/GaN power amplifier MMIC could be applicable to various X-band radar systems operating X-band.

Hong Jung Ha's Number Theory (홍정하(洪正夏)의 수론(數論))

  • Hong, Sung-Sa;Hong, Young-Hee;Kim, Chang-Il
    • Journal for History of Mathematics
    • /
    • v.24 no.4
    • /
    • pp.1-6
    • /
    • 2011
  • We investigate a method to find the least common multiples of numbers in the mathematics book GuIlJib(구일집(九一集), 1724) written by the greatest mathematician Hong Jung Ha(홍정하(洪正夏), 1684~?) in Chosun dynasty and then show his achievement on Number Theory. He first noticed that for the greatest common divisor d and the least common multiple l of two natural numbers a, b, l = $a\frac{b}{d}$ = $b\frac{a}{d}$ and $\frac{a}{d}$, $\frac{b}{d}$ are relatively prime and then obtained that for natural numbers $a_1,\;a_2,{\ldots},a_n$, their greatest common divisor D and least common multiple L, $\frac{ai}{D}$($1{\leq}i{\leq}n$) are relatively prime and there are relatively prime numbers $c_i(1{\leq}i{\leq}n)$ with L = $a_ic_i(1{\leq}i{\leq}n)$. The result is one of the most prominent mathematical results Number Theory in Chosun dynasty. The purpose of this paper is to show a process for Hong Jung Ha to capture and reveal a mathematical structure in the theory.