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Antibacterial and Radical Scavenging Activities of 1-C-(p-Hydroxyphenyl)-Glycerol from Trichosanthes kirilowii

  • Jang, Ki-Chang;Lee, Jin-Hwan;Kim, Seong-Cheol;Song, Eun-Young;Ro, Na-Young;Moon, Doo-Young;Um, Yeong-Cheol;Park, Ki-Hun
    • Journal of Applied Biological Chemistry
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    • v.50 no.1
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    • pp.17-21
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    • 2007
  • 1-C-(p-Hydroxyphenyl)-glycerol (1) was isolated and purified by column chromatography and recrystallization from the rhizome of Trichosanthes kirilowii, firstly in this species. Isolated compound showed inhibitory effects on the growth of five bacteria (Bacillus cereus, Escherichia coli, Streptococcus faecalis, etc) completely at the concentration higher than 10 ppm as well as delayed the growth of three bacteria (Bacillus substilis, Staphylococcus aureus, Pseudomonas aeroginosa) at the concentration of 25 ppm for 60 h. Moreover, this compound showed potent antioxidant activity against DPPH radical ($IC_{50}$ = 56.0 ppm)

2-D & 3-D Observations on the microstructures of Super Bainitie TRIP Steels using Total Analysis System (TAS (Total Analysis System)를 이용한 SB-TRIP강에서의 2-D & 3-D 미세구조 분석 연구)

  • Seol, J.B.;Lim, Y.R.;Park, C.G.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2009.10a
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    • pp.209-212
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    • 2009
  • It has been widely reported that carbide-free bainitic steels or super-bainite WP (SB-TRIP) steels for the automotive industry are a new family of steels offering a unique combination of high strength and ductility. Hence, it is important to exactly evaluate the volume fraction of RA and to identify the 3-D morphology of constituent phases, because it plays a crucial role in mechanical properties. Recently, as electron back-scattered diffraction (EBSD) equipped with focused ion beam (FIB) has been developed, 3-D EBSD technique for materials science are used to these steels. Moreover, newly developed atom probe tomography (APT) technique can provide the exact distribution and chemical concentration of alloying elements in a sub-nm scale. The APT analysis results indicate exactly the distribution and composition of alloying elements in the austenite and bainite phases of SB-TRIP steels with the atomic-scale resolution. And thus, no partitioning of aluminum and manganese atoms was showed between the austenite containing $7.73{\pm}0.39$ at% C and the bainitic ferrite associated with $0.22{\pm}0.06$ at% C in the SB-TRIP steel.

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2-D & 3-D Observations on the Microstructure of Super Bainite TRIP Steels using Total Analysis System (TAS(Total Analysis System)을 이용한 SB-TRIP강에서의 2-D & 3-D 미세구조 분석 연구)

  • Seol, J.B.;Lee, B.H.;Park, C.G.
    • Transactions of Materials Processing
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    • v.19 no.1
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    • pp.44-49
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    • 2010
  • It has been widely reported that carbide-free bainitic steels or super-bainite TRIP (SB-TRIP) steels for the automotive industry are a new family of steels offering a unique combination of high strength and ductility. Hence, it is important to exactly evaluate the volume fraction of RA and to identify the 3-D morphology of constituent phases, because it plays a crucial role in mechanical properties. Recently, as electron back-scattered diffraction (EBSD) equipped with focused ion beam (FIB) has been developed, 3-D EBSD technique for materials science are used to these steels. Moreover, newly developed atom probe tomography (APT) technique can provide the exact distribution and chemical concentration of alloying elements in a sub-nm scale. The APT analysis results indicate exactly the distribution and composition of alloying elements in the austenite and bainite phases of SB-TRIP steels with the atomic-scale resolution. And thus, no partitioning of aluminum and manganese atoms was showed between the austenite containing $7.73{\pm}0.39$ at% C and the bainitic ferrite associated with $0.22{\pm}0.06$ at% C in SB-TRIP steel.

Antioxidative Flavonoids from Leaves of Carthamus tinctorius

  • Lee, Jun-Young;Chang, Eun-Ju;Kim, Hyo-Jin;Park, Jun-Hong;Choi, Sang-Won
    • Archives of Pharmacal Research
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    • v.25 no.3
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    • pp.313-319
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    • 2002
  • A total of eight flavonoids (1-8), including a novel $quercetin-7-o-(6"-o-acetyl)-{\beta}-D-glucopyranoside$ (6) and seven known flavonoids, luteolin (1), quercetin (2), luteolin $7-o-{\beta}-D-glucopyranoside$ (3), $luteolin-7-o-(6"-Ο-acetyl)-{\beta}-D-glucopyranoside$ (4) quercetin $7-o-{\beta}-D-glucopyranoside$ (5), acacetin 7-o-{\beta}-D-glucuronide (7) and apigenin-6-C-{\beta}-D-glucopyrano $syl-8-C-{\beta}-D-glucopyranoside$ (8), have been isolated from the leaves of the safflower (Carthamus tinctorius L.) and identified on the basis of spectroscopic and chemical studies. The antioxidative activity of these flavonoids was evaluated against 2-deoxyribose degradation and rat liver microsomal lipid peroxidation induced by hydroxyl radicals generated via a Fenton-type reaction. Among these flavonoids, luteolin-acetyl-glucoside (4) and quercetin-acetyl-glucoside (6) showed potent antioxidative activities against 2-deoxyribose degradation and lipid peroxidation in rat liver microsomes. Luteolin (1), quercetin (2), and their corresponding glycosides (3 & 5) also exhibited strong antioxidative activity, while acacetin glucuronide (7) and apigenin-6,8-di-C-glucoside (8) were relatively less active.

The Underwater Propagation of the Noise of Ship's Engine (기관소음의 수중전파에 관한 연구)

  • 박중희
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.16 no.2
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    • pp.69-76
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    • 1980
  • This paper describes the measurement of the underwater noises produced by the engine vibration around the engine room of stern trawler MIS Sae-Ba-Da(2275GT, 3,600 PS) and pole kner M/S Kwan-Ak-San (243 GT, 1000 PS) while the ship is stopping. The underwater noise pressure level was measured with the underwater level meter of which measuring range is 100 to 200 dB(re bLPa). A and B denotes the maximum pressure level measured at right beneath the bottom of the engine room, while the main engine of the Sae-Ba-Da revoluted at 750 and 500 rpm, respectively. C denotes that of the main engine of the Kwan-Ak-San revoluted at 350 rpm, and D that of the generator of the Sae-Ba-Da revoluted at 720 rpm. Thus A, B, C and D were set for the standard sound source for the experiment. The results obtained are as follows: 1. The noise Pressure level at A, B, C and D were 170.5,165,153 and 158dB, respectively. 2. When the check points distanted vertically 1, 10, 20, 30, 40, 50m from the sound source, the underwater noise presure levels were 170.5, 155, 148, 144 and 138 dB and the directional angle was 116\ulcorner in case of A. 3. The sound level attenuated at the rate of 20dB per 10" meters of the horizontal distance from the sound sources. 4. The frequency distribution of the noise was 100Hz to 10KHz and predominant frequency was 700 to 800Hzminant frequency was 700 to 800Hz

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Equilibrium Geometries of the Neutral and Ionic Clusters of $Ag_7$, $Ag_8$, and $Ag_9$ Studied by Intermediate Neglect of Differential Overlap Method

  • Yu, Chang Hyeon;Seon, Ho Seong
    • Bulletin of the Korean Chemical Society
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    • v.21 no.10
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    • pp.953-954
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    • 2000
  • The equilibrium geometrical structures of silver atom clusters at their electronic ground states have been theo-retically determined by using the nonrelativistic semiempirical INDO/1 method. The clusters investigated are Agn, Agn+, and Agn- (n = 7 , 8, 9). In order to find the most stable structure, i.e., the global minimum in energy hypersurface, geometry optimization and energy calculation processes have been repeatedly performed for all the possible graphical models by changing the bond parameters (resonance integral values). The heptamers are pentagonal bipyramidal-Ag7(D5h), Ag7+ (D5h), Ag7- (D5h); the octamers are pentagonal bipyramidal with one atom capped-Ag8(D2d), Ag8+ (Cs), Ag8- (D2d); the nonamers are pentagonal bipyramidal with two atoms capped -Ag9(C2v), Ag9+ (C2v), Ag9- (C2v). Our structures are in good agreement with those by ab initio calculations ex-cept for the anionic Ag9- cluster. And it is noted that the INDO/1 method can accurately predict the Ag cluster geometries when a proper set of bond parameters is used.

The Combination Effect of Kinetin and Auxin on the Growth Root Development and Vitamin C Content of Soybean sprouts (콩나물의 성장과 Vitamin C 생성에 미치는 Kinetin과 Auxin의 혼합효과)

  • Kim, Sang-Ock
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.11 no.2
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    • pp.37-41
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    • 1982
  • This study was conducted to investigate the growth of soybean sprouts and the effective hormonal refutation of vitamin C content by the concentration and combination of kinetin and auxins such as IAA, 2.4-D and NAA. The results were as follows; 1. The growth of soybean sprouts were fine under the respective conditions of kinetin $10^{-8}M+IAA\;10^{-6}M$, kinetin $10^{-7}M+IAA\;10^{-5}M$, kinetin $10^{-6}M+IAA\;10^{-6}M$, kinetin $10^{-5}M+IAA\;10^{-7}M$, kinetin $10^{-8}M+2,4-D\;10^{-8}M$ and kinetin $10^{-7}M+NAA\;10^{-5}M$. 2. The root development of soybean sprouts were almost in accord with the growth of soybean sprouts by the concentration of kinetin and auxin. 3. The content of vitamin C were more increased under in kinetin $10^{-8}M+IAA\;10^{-8}M$, kinetin $10^{-6}M+2,4-D\;10^{-5}M$ and kinetin $10^{-8}M+NAA\;10^{-8}M$ and both growth and vitamin C content were more activated under kinetin $10^{-8}M+IAA\;10^{-6}M$ and $10^{-8}M+NAA\;10^{-8}M$. 4. The growth, root development and vitamin C content were increased in the low kinetin and high IAA, NAA concentration. Root development and vitamin C content of soybean hypocotyl were decreased in the low kinetin and high 2,4-D concentration.

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Isolation and Structural Determination of a Complete Set of Intact Bacteriochlorophyll-d Homologs and Isomers from Green Sulfur Bacterium Chlorobium vibrioforme and Their Aggregation Properties in Hydrophobic Solvents

  • Mizoguchi, Tadashi;Saga, Yoshitaka;Tamiaki, Hitoshi
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.344-346
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    • 2002
  • Eight intact bacteriochlorophyll (BChl)-d homologs and isomers were isolated from a strain of green sulfur bacterium Chlorobium vibrioforme. All the molecular structures of the BChl-d components were fully determined by a combination of mass spectrometry and $^1$H-NMR spectroscopy. The aggregation behavior of the isomerically pure BChls-d in hydrophobic organic solvents was examined with respect to the stereoisomeric configuration at the C3$^1$ position as well as the bulkiness of the C8 and C12 side-chains by using electronic- absorption spectroscopy.

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Determination of the optical isomers of ethambutol (myambutol) and 2-amino-1-butanol by gas-liquid chromatography

  • Kim, Ye-Sook;Youm, Jeong-Rok;Park, Man-Ki;Paik, Nam-Ho
    • Archives of Pharmacal Research
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    • v.4 no.1
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    • pp.1-8
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    • 1981
  • Our need for a convenient method of analytical estimation of the precise optical purity of d-2 aminobutanol (d-2AB) and d-ethambutol has prompted us to examine in detail the preparation and G. L. C. separation of the N-TFA-L-prolyl derivatives of their optical isomers (d-and l-2AB, d-, meso-and l-ethambutol). Silicon OV-1 columns were used for the G. L. C. separation.

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ON BOUNDED OPERATOR Qq IN WEIGHT BLOCH SPACE

  • Choi, Ki Seong
    • Journal of the Chungcheong Mathematical Society
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    • v.13 no.1
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    • pp.131-138
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    • 2000
  • Let D be the open unit disk in the complex plane $\mathbb{C}$. For any q > 0, the operator $Q_q$ defined by $$Q_qf(z)=q\int_{D}\frac{f(\omega)}{(1-z{\bar{\omega}})^{1+q}}d{\omega},\;z{\in}D$$. maps $L^{\infty}(D)$ boundedly onto $B_q$ for each q > 0. In this paper, weighted Bloch spaces $\mathcal{B}_q$ (q > 0) are considered on the open unit ball in $\mathbb{C}^n$. In particular, we will investigate the possibility of extension of this operator to the Weighted Bloch spaces $\mathcal{B}_q$ in $\mathbb{C}^n$.

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