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A Prospective Study for Risk Factors Predicting Postoperative Pulmonary Complications (수술 후 폐 합병증 발생의 위험 인자에 대한 연구)

  • Chon, Su Yeon;Kim, Yu Jin;Kyung, Sun Young;Ahn, Chang Hyeok;Lee, Sang Pyo;Park, Jeong Woong;Jeong, Sung Hwan
    • Tuberculosis and Respiratory Diseases
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    • v.62 no.6
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    • pp.516-522
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    • 2007
  • Background: Postoperative pulmonary complications are important problems that prolong the length of the hospital stay and increase patient mortality. However, our knowledge of the postoperative factors that increase the risk of these complications is less than complete. Methods: We conducted a prospective study to determine the risk factors for postoperative pulmonary complications. A total of 199 patients were referred to the Pulmonology Department for preoperative pulmonary evaluation. We reviewed the perioperative variables according to the National Surgical Quality Improvement Program (NSQIP). Postoperatively, we collected data on the occurrence of postoperative pulmonary complications and we evaluated the relationship between the perioperative variables and outcomes. Results: Twenty two patients (11%) had pulmonary complications; 6 had respiratory failure, 4 had pneumonia, 13 had pleural effusion and, 2 had atelectasis. Five variables were statistically significantly associated with pulmonary complications on the bivariate analyses. Multiple logistic regression analyses revealed that three of these variables were independently associated with an increased risk of pulmonary complications; a high cardiac risk index (OR 16.5, p=0.002), emergency surgery (OR 10.3, p=0.017), and thoracic/abdominal surgery (OR 3.8, p=0.047). Conclusion: The risk factors for postoperative pulmonary complications are a high cardiac risk index, emergency surgery and thoracic/abdominal surgery.

Effect of Ga-doping on the properties of ZnO films grown on glass substrate at room temperature by radio frequency magnetron sputtering (RF 마그네트론 스퍼터링 방법으로 상온에서 유리기판 위에 성장시킨 ZnO의 성질에 미치는 Ga 도핑 효과)

  • Kim, G.C.;Lee, J.S.;Lee, S.K.;Kim, D.H.;Lee, S.H.;Moon, J.H.;Jeon, M.H.
    • Journal of the Korean Vacuum Society
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    • v.17 no.1
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    • pp.40-45
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    • 2008
  • We present the effect of Ga-doping on the electrical, structural and optical properties of ZnO layers with a thickness of ${\sim}500nm$ deposited on glass substrates. Polycrystalline ZnO and Ga-doped ZnO (GZO) layers were deposited by radio frequency (rf) magnetron sputtering at room temperature. Based on the X-ray diffraction (XRD) and transmission electron microscopy (TEM) data, the crystalline quality of Ga-doped ZnO film was improved and GZO film has a preferred orientation along with the (002) crystal direction. The transmittance of the GZO film was enhanced by 10% in the visible region from that of the ZnO film. From photoluminescence (PL) data, the ratio of intensity of near band edge (NBE) emission to deep level (DL) emission was as high as 2.65:1 and 1.27:1 in the GZO and ZnO films, respectively. The res istivities of GZO and ZnO films were measured to be 1.27 and 1.61 $\Omega{\cdot}cm$, respectively. The carrier concentrations of ZnO and GZO film were approximately 1018 and 1020 $cm^2$/Vs, respectively. Based on our experimental results, the Ga-doping improves the electrical, structural and optical properties of ZnO film with potential application.

Knowledge, Attitude and Performance Ability of Automated External Defibrillator and Cardiopulmonary Resuscitation among Korean University Students (비보건계열 대학생의 자동제세동기와 심폐소생술에 대한 지식, 태도 및 수행능력)

  • Kim, Mi Hwa;Lee, Eun-Sook;Jun, Sang-Eun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.2
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    • pp.156-163
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    • 2016
  • This study examined the level of knowledge, attitude, and performance ability of automated external defibrillator (AED) and cardiopulmonary resuscitation (CPR) among university students who were not in health-related majors and to explore the relationships among these variables. In this study, 291 students were recruited from 3 universities in D city. Among them, 77.0% had ever seen or heard of AED and 61.9% did not know how to use it. The levels of knowledge, attitudes and performance ability differed significantly according to the CPR training experience and AED awareness (p<.002~.001). The performance ability showed significant correlations with knowledge (r=. 42, p<.001) and attitude (r=. 55, p<.001) of AED and CPR. These findings suggest that future AED and CPR training programs should be developed to promote a positive attitude towards the willingness to perform AED and CPR as well as to increase the participants' confidence by repeated training.

Effect of Education and Counselling-based Cardiac Rehabilitation Program on Cardiovascular Risk, Health Behavior and Quality of Life in Elderly with Coronary Artery Disease (교육상담 기반 심장재활 프로그램이 노인 관상동맥질환자의 심혈관 위험도, 건강행위 및 삶의 질에 미치는 효과)

  • Won, Mi-Hwa
    • The Journal of the Korea Contents Association
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    • v.15 no.6
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    • pp.303-313
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    • 2015
  • Purpose: The purpose of this study was to investigate the effect of education and counselling-based cardiac rehabilitation program on cardiovascular risk, health behavior and quality of life in elderly with coronary artery disease. Methods: A quasi-experimental study used a non-equivalent control group pre-post test design. A five week education and counselling-based cardiac rehabilitation program for the elderly with coronary artery disease was developed and offered to the experimental group. Participants were drawn from hospital in Busan. Twenty two were selected for the experimental group while 22 were assigned to a control group. Cardiovascular risk, health behavior and quality of life were measured. Results: There was a statistically significant difference in the cardiovascular risk(U=118.5, p=.002), health behaviors(t=5.200, p=<.001) and quality of life(t=2.431, p=.001) between the experimental group and the control group. Conclusion: Education and counselling-based cardiac rehabilitation program can be not only an effective nursing intervention for old patients having coronary artery disease, but also the very basis of further research on aged people who have the same symptom.

Corrosion resistance and crystal growth mechanism of Mg films prepared on steel substrate and hot dip aluminized steel by PVD sputtering method (PVD 스퍼터링법에 의해 강판 및 용융알루미늄 도금강판 상에 제작한 Mg 코팅막의 결정성장 메커니즘과 내식특성)

  • Park, Jae-Hyeok;Lee, Seul-Gi;Park, Jun-Mu;Mun, Gyeong-Man;Yun, Yong-Seop;Jeong, Jae-In;Lee, Myeong-Hun
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2018.06a
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    • pp.115-115
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    • 2018
  • 철강재는 대량 생산이 가능하며 경제성이 뛰어나고 기계적 성질도 우수하므로 다양한 산업 분야에서 널리 사용되고 있다. 그러나 철강재는 부식 환경에 취약하기 때문에 그 용도에 따라 다양한 내식성을 부여하는 표면처리를 적용하고 있다. 일반적으로 이러한 철강 재료에 대한 내식성 표면처리로는 습식공정을 이용한 아연(Zn)도금 표면처리가 널리 적용되고 있다. 그러나 최근에는 이러한 습식공정으로 인해 발생하는 자원소모 및 환경적인 문제와 더불어 고내식성 표면처리 소재에 대한 수요가 증가함에 따라 이러한 단점을 극복할 수 있는 새로운 소재 및 기술 개발에 대한 관심이 증대되고 있다. 이러한 관점에서 기존의 습식표면처리 공정을 건식으로 대체 또는 병행하고, 현행 아연소재를 대체할 수 있는 코팅소재로써 알루미늄(Al) 이나 마그네슘(Mg)으로 대체하는 방법이 시도되고 있다. 본 연구에서는 강판의 내식성을 향상시키기 위한 방법으로 기존의 습식 표면처리 공정에서 용이하지 않은 마그네슘을 이용하여 건식 PVD 프로세스에 의해 코팅막의 제작을 시도하였다. 그리고 코팅막 제작 조건 중에서 공정압력이 코팅막의 결정배향성에 미치는 영향과 내식성과의 상관관계를 규명하고자 하였다. 즉, 여기서는 강판 및 용융알루미늄 도금강판 상에 스퍼터링법에 의해 Ar 가스에 의한 공정압력을 2, 10 및 50 mTorr로 조절하면서 마그네슘 코팅막을 $2{\mu}m$ 두께로 각각 제작하였다. 이때 제작한 막의 표면 모폴로지 관찰(SEM) 및 결정구조 분석(XRD) 결과에 의하면, 강판 및 용융알루미늄도금강판 상에 제작한 코팅막들은 공통적으로 공정압력이 증가할수록 그모폴로지의 결정립의 크기가 작고 치밀한 구조로 변하였다. 또한 그때 형성된 코팅막의 결정구조는 표면에너지가 상대적으로 높은 Mg(002)면 피크의 점유율이 감소하고 표면에너지가 낮은 Mg(101)면 피크의 점유율이 증가하는 경향을 나타내었다. 그리고 공정압력이 증가할수록 Mg 격자 간 면 간격(d-value)이 증가하는 경향을 나타내었다. 이상에서 제작한 마그네슘 코팅막의 결정성장 과정은 본 진공 플라즈마 PVD 공정중 증착가 더불어 흡착역할을 하는 Ar의 움직임에 따라 설명 가능하였다[1,2]. 코팅막의 양극분극(Polarization)측정 결과에 의하면, 공정압력이 높은 조건에서 제작한 막일수록 부동태 특성이 우수하여 내식성이 향상되는 경향을 나타내었다. 특히, 공정압력이 상대적으로 높은 50 mTorr 조건에서 제작된 코팅막이 표면 마그네슘 결정의 크기가 조밀하고 결정구조는 Mg(002)면과 Mg(101)면의 상대강도 비가 유사하여 내식성 가장 우수하였다.

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THE VLBI MONITORING PROJECT FOR 6.7 GHz METHANOL MASERS USING THE JVN/EAVN

  • SUGIYAMA, KOICHIRO;FUJISAWA, KENTA;HACHISUKA, KAZUYA;YONEKURA, YOSHINORI;MOTOGI, KAZUHITO;SAWADA-SATOH, SATOKO;MATSUMOTO, NAOKO;SAITO, YU;HIRANO, DAIKI;HAYASHI, KYONOSUKE;SHEN, ZHIQIANG;HONMA, MAREKI;HIROTA, TOMOYA;MURATA, YASUHIRO;DOI, AKIHIRO;NIINUMA, KOTARO;DODSON, RICHARD;RIOJA, MARIA;ELLINGSEN, SIMON;CHEN, XI;KIM, KEE-TAE;OGAWA, HIDEO
    • Publications of The Korean Astronomical Society
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    • v.30 no.2
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    • pp.645-647
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    • 2015
  • We have initiated a Very Long Baseline Interferometer (VLBI) monitoring project of 36 methanol maser sources at 6.7 GHz using the Japanese VLBI Network (JVN) and East-Asian VLBI Network (EAVN), starting in August 2010. The purpose of this project is to systematically reveal 3-dimensional (3-D) kine-matics of rotating disks around forming high-mass protostars. As an initial result, we present proper mo- tion detections for two methanol maser sources showing an elliptical spatial morphology, G 002.53+00.19 and G 006.79-00.25, which could be the best candidates associated with the disk. The detected proper motions indicate a simple rotation in G 002.53+00.19 and rotation with expansion in G 006.79-00.25, respectively, on the basis of disk model fits with rotating and expanding components. The expanding motions might be caused by the magnetic-centrifugal wind on the disk.

MYLK Polymorphism Associated with Blood Eosinophil Level among Asthmatic Patients in a Korean Population

  • Lee, Soo Ok;Cheong, Hyun Sub;Park, Byung Lae;Bae, Joon Seol;Sim, Won Chul;Chun, Ji-Yong;Isbat, Mohammad;Uh, Soo-Taek;Kim, Yong Hooun;Jang, An-Soo;Park, Choon-Sik;Shin, Hyoung Doo
    • Molecules and Cells
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    • v.27 no.2
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    • pp.175-181
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    • 2009
  • The myosin light chain kinase (MYLK) gene encodes both smooth muscle and nonmuscle cell isoforms. Recently, polymorphisms in MYLK have been reported to be associated with several diseases. To examine the genetic effects of polymorphisms on the risk of asthma and related phenotypes, we scrutinized MYLK by re-sequencing/genotyping and statistical analysis in Korean population (n = 1,015). Seventeen common polymorphisms located in or near exons, having pairwise $r^2$ values less than 0.25, were genotyped. Our statistical analysis did not replicate the associations with the risk of asthma and log-transformed total IgE levels observed among African descendant populations. However, two SNPs in intron 16 (+89872C> G and +92263T> C), which were in tight LD (|D'| = 0.99), revealed significant association with log-transformed blood eosinophil level even after correction multiple testing ($P=0.002/P^{corr}=0.01$ and $P=0.002/P^{corr}=0.01$, respectively). The log-transformed blood eosinophil levels were higher in individuals bearing the minor alleles for +89872C> G and +92263T> C than in those bearing other allele. In additional subgroup analysis, the genetic effects of both SNPs were much more apparent among asthmatic patients and atopic asthma patients. Among atopic asthma patients, the log-transformed blood eosinophil levels were proportionally increased by gene-dose dependent manner of in both +89872C> G and +92263T> C(P = 0.0002 and P = 0.00007, respectively). These findings suggest that MYLK polymorphisms might be among the genetic factors underlying differential increases of blood eosinophil levels among asthmatic patients. Further biological and/or functional studies are needed to confirm our results.

Self-Limiting Growth of ZnO Thin Films and Substrate-Temperature Effects on Film Properties (자기제한적 표면반응에 의한 ZnO 박막성장 및 기판온도에 따른 박막특성)

  • Lee, D.H.;Kwon, S.R.;Lee, S.K.;Noh, S.J.
    • Journal of the Korean Vacuum Society
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    • v.18 no.4
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    • pp.296-301
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    • 2009
  • An inductively coupled plasma assisted atomic layer deposition(ICP-ALD) system has been constructed for the deposition of ZnO thin films, and various experiments of ZnO thin films on p-type Si(100) substrates have been carried out to find the self-limiting reaction conditions for the ICP-ALD system under non-plasma circumstances. Diethyl zinc[$Zn(C_2H_5)_2$, DEZn] was used as the zinc precursor, $H_2O$ as the oxidant, and Ar as the carrier and purge gas. At the substrate temperature of $150^{\circ}C$, atomic layer deposition conditions based on self-limiting surface reaction were successfully obtained by series of experiments through the variation of exposure times for DEZn, $H_2O$, and Ar. ZnO deposition was repeated at different substrate temperatures of $90{\sim}210^{\circ}C$. As a result, the thermal process window(ALD window) for ZnO thin films was observed to be $110{\sim}190^{\circ}C$ and the average growth rate was measured to be constant of 0.29 nm/cycle. Properties of the film's microstructure and composition(Zn, O, etc.) were also studied. As the substrate temperature increases, the crystallinity was improved and ZnO(002) peak became dominant. The films deposited at all temperatures were high purity, and the films deposited at high temperatures had the composition ratio between Zn and O closer to one of a stable hexagonal wurtzite structure.

A study on combination of loss functions for effective mask-based speech enhancement in noisy environments (잡음 환경에 효과적인 마스크 기반 음성 향상을 위한 손실함수 조합에 관한 연구)

  • Jung, Jaehee;Kim, Wooil
    • The Journal of the Acoustical Society of Korea
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    • v.40 no.3
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    • pp.234-240
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    • 2021
  • In this paper, the mask-based speech enhancement is improved for effective speech recognition in noise environments. In the mask-based speech enhancement, enhanced spectrum is obtained by multiplying the noisy speech spectrum by the mask. The VoiceFilter (VF) model is used as the mask estimation, and the Spectrogram Inpainting (SI) technique is used to remove residual noise of enhanced spectrum. In this paper, we propose a combined loss to further improve speech enhancement. In order to effectively remove the residual noise in the speech, the positive part of the Triplet loss is used with the component loss. For the experiment TIMIT database is re-constructed using NOISEX92 noise and background music samples with various Signal to Noise Ratio (SNR) conditions. Source to Distortion Ratio (SDR), Perceptual Evaluation of Speech Quality (PESQ), and Short-Time Objective Intelligibility (STOI) are used as the metrics of performance evaluation. When the VF was trained with the mean squared error and the SI model was trained with the combined loss, SDR, PESQ, and STOI were improved by 0.5, 0.06, and 0.002 respectively compared to the system trained only with the mean squared error.

Extraction of Total Flavonoids from Lemongrass Using Microwave Energy: Optimization Using CCD-RSM (마이크로웨이브 에너지를 이용한 레몬그라스로부터 플라보노이드 성분의 추출: CCD-RSM을 이용한 최적화)

  • Yoo, Bong-Ho;Jang, Hyun Sick;Lee, Seung Bum
    • Applied Chemistry for Engineering
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    • v.32 no.2
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    • pp.168-173
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    • 2021
  • In this study, we measured total flavonoids after extracting the total flavonoids from lemongrass which is known to have a high content of antioxidant ingredients when using microwave energy. Also, optimal extraction conditions of active ingredients using central composite design-response surface methodology (CCD-RSM) were presented. Both ultrapure water and alcohol were used as extraction solvents and the volume ratio of ethanol/ultrapure water, microwave irradiation time, and microwave irradiation power were set as independence variables. And the extraction yield and total flavonoids were measured. The optimal extraction conditions using CCD-RSM were the volume ratio of ethanol/ultrapure water = 56.3 vol.%, the microwave irradiation time = 6.1 min, and the microwave irradiation power = 574.6 W. We could also obtain expected results of yield = 17.2 wt.% and total flavonoids = 44.7 ㎍ QE/mL dw under the optimum conditions. The comprehensive satisfaction degree of this formula was 0.8562. The P-value was calculated for the yield of 0.037 and the total flavonoids content of 0.002. The average error from actual experiments established for the verification of conclusions was lower than 2.5%. Therefore, a high favorable level could be obtained when the CCD-RSM was applied to the optimization of extraction process.