• 한국임상수의학회지
• /
• 제24권1호
• /
• pp.59-61
• /
• 2007

Eosinophilic cystitis (EC) is a rare inflammatory disorder in dogs. Although EC has been associated with various etiological factors, the precise cause of this disease remains unclear in human and animals. A 7-year-old female Yorkshire terrier was presented with 3-week-history of hematuria, dysuria, and suprapubic pain. A bladder mass in ventral surface and urinary calculi were noted on ultrasonography and gross findings. Biopsy sample was taken from the protruded mass of bladder for histopathologic examination. Hyperplastic transitional epithelium with focal ulceration covered the bladder mass. A large nodule of fibrous tissue that contained fibrocytes, fibroblasts, Iymphocytes, plasma cells, macrophages, numerous eosinophils, and abundant blood vessels was occupied in lamina propria and submucosa of bladder mass. Based on the clinical, gross, and histopathologic examinations, this case was diagnosed as EC in a dog. In our knowledge, this is the first report of an eosinophilic cystitis in dog in Korea.

• Journal of Yeungnam Medical Science
• /
• 제26권2호
• /
• pp.143-147
• /
• 2009

Hemorrhagic cystitis (HC) is a common complication after allogeneic transplantation. Early posttransplant HC occurs in association with cyclophosphamide, while later on HC results from viral infections such as polyomavirus BK (BKV) and adenovirus. We report here the case of a 57-year-old woman who received an instillation of cidofovir into the bladder for the treatment of hemorrhagic cystitis after allogeneic peripheral stem cell transplantation for her acute myeloid leukemia. Cyclophosphamide and busulfan were used as conditioning treatments. Cyclosporin was administered daily. On the 71st day after transplantation, the patient developed acute severe hemorrhagic cystitis, and BK virus was demonstrated in the urine samples using polymerase chain reaction. Her urinary symptoms did not improve in spite of palliative treatment, but a response was evident after intravesical cidofovir treatment.

• 대한한방내과학회지
• /
• 제26권2호
• /
• pp.475-481
• /
• 2005

Objectives: This study was designed to evaluate the effects of an oriental medicine therapy, namely Bojoongikkitang-gamibang, on a chronic cystitis patient. Methods: The clinical data was analyzed on a patient with chronic cystitis due to Bigiheoyak(脾氣虛弱) and Junggihaham(中氣下陷) whose main symptoms were urinary disturbances, such as urgency, weak stream, hesitancy and nocturia, etc. The patient visited twice at the internal medicine department of Dae-Gu Hanny University Dae-Gu Oriental Medicine Hospital on May 20, and on June 3, 2004 and was only treated with herbal medicine(Bojoongikkitang-gamibang). Results: After treatment, improvement was seen in the subsection of the International Prostate Symptom Score(IPSS). Conclusions: This study suggests that Bojoongikkitang-gamibang is significantly effective in treatment of a chronic cystitis.

• 대한수의학회지
• /
• 제57권2호
• /
• pp.139-141
• /
• 2017

An 8-year-old castrated male Shih Tzu dog (weighing 7.0 kg) presented with anemia and lethargy. Initial diagnosis indicated immune-mediated hemolytic anemia. During therapy, a secondary urinary infection, probably due to the immune suppressive therapy, was diagnosed. Subsequent diagnostic tests, including urinalysis and urine culture, indicated candidal cystitis. Despite ketoconazole therapy for candidal cystitis, the dog died suddenly. A Candida albicans infection was confirmed upon postmortem evaluation. Prolonged immunosuppressive therapy might be the cause of this infection. This is the first case report describing a Candida albicans urinary tract infection accompanied by hemolytic anemia in a dog in Korea.

• 대한수의학회지
• /
• 제36권4호
• /
• pp.973-990
• /
• 1996

To investigate diagnostic imaging of cystitis and to apply it to the small animal practice, ultrasonogram of urinary bladder with moderate distension(4ml/kg) and with complete distension(9ml/kg) to evaluate the irregularity and thickness of bladder, radiography and histopathological examination were performed after experimental cystitis induction. On double contrast cystography, mucosal membrane of the urinary bladder was smooth and thickening urinary bladder wall was not found before cystitis induction. At 3rd day post induction(PI), mucosal irregularity was noted at the cranioventral region of the urinary bladder. Thickening of the urinary bladder wall and filling defect was observed as well. Cystographic findings of 7, 10, 15, 21 day PI were similar to that of 3rd day PI. On ultrasonographic findings of the mural thickness in induction group, it was ascertain that the mural thickness with moderate distention was more thickened than with complete distention at transverse scan. Ultrasonographic findings at longitudinal scan were similar to those of transverse scan. On ultrasonographic findings of mucosal irregularity in induction group, from PI to 7 day PI, mucosal irregularity with moderate distention was more irregular than mucosal irregularity with complete distention. At 10 day PI, there was similarity between moderate distention and complete distention. On histopathologic examination of a section of urinary bladder taken 3 day PI, the mucosal and submucosa were infiltrated by a mixture of thick inflammatory exudate which was composed of neutrophil, plasma protein, bacterial colony and necrotic cells. Congestion, hemorrhage and edema were also observed in the submucosa. At 7th day PI, the mucosal change was similar to that of 3rd day PI, but neovascularization and fibroplasia were observed in the submucosa. At 15th and 21th day PI, mild hyperplasia of mucosal epithelium was observed in the mucosa. Deposition of collagen, neovascularization and severe diffuse infiltration of lymphocyte were observed. These results suggest that ultrasonographic examination with moderate distention is considered to be a more simple, rapid, noninvasive, sensitive and useful diagnostic method than other diagnostic methods for the diagnosis of the cystitis and the differential diagnosis of urinary tract infection.

• 셀메드
• /
• 제13권3호
• /
• pp.9.1-9.4
• /
• 2023

Objective: A case report on improvements in complex diseases (recurrent cystitis, etc.) through the use of nutritional therapy Methods: A 56-year-old Korean female. The patient has various diseases and her quality of life has been reduced due to health problems. Results: Complex diseases were improved after undergoing nutritional therapy. Conclusion: Nutritional therapy can assist in treating complex diseases.

• Journal of Acupuncture Research
• /
• 제18권4호
• /
• pp.212-220
• /
• 2001

간질성 방광염이란 성인여성에게 생기는 질환으로 일종의 근육에 생긴 염증이며 미국에서는 아주 흔한 질환이나 국내에서는 그 동안 진단기준이 없어 단순한 방광염으로 오인 되어왔다. 증상은 일반적인 방광염과 비슷하나 너무 자주 재발하고 잘 낫지 않으며 방광용적의 감소로 빈뇨와 급뇨, 하복부와 회음부의 통증이 흔하고 방광을 비우면 증상은 호전되는 양상을 보인다. 진단을 확진할 정확한 검사가 없기 때문에 반드시 다른 질환이 없슴을 증명하여야 한다. 즉 방광염을 일으키는 원인들인 요로 감염, 골반염, 결핵, 결석, 성병, 전립선염, 방광암 등이 없이 빈뇨와 소변을 참지 못하고 하복통이 있을 때 일단 의심을 하고 방광내시경상에 방광 벽의 염증이나 점상성 출혈, 궤양이 있으면 확진한다. 양방에서는 한가지 완벽한 치료가 없어 여러 가지 복합적인 치료를 하며 일차적으로는 약물요법과 방광확장술을 시도한다. 먹는 약으로는 아직 공인된 것은 없으며 이 약들은 증상의 호전은 기대할 수 있으나 일시적인 경우가 많으며 결국은 방광확장술을 추가하는 경우가 대부분이다. 이에 이 질환을 갖고 있는 여자 환자에게 침 치료를 시행한 결과 주관적인 통증과 급박감에 있어서 감소와 객관적인 소변 횟수의 감소에 있어 만족할 만한 효과를 얻었기에 보고하는 바이다.

• Journal of Acupuncture Research
• /
• 제19권6호
• /
• pp.193-204
• /
• 2002

Interstital cystitis(IC) is a disease of the bladder that is characterized by inveterate irritation due to non-specific chronic inflammation. The symptoms of IC are chronic pain, frequency, urgency and sleep deprivation These symptom's are contained to the Lunbing(淋病) in oriental medicine. We observed 4 cases of patient with Interstitial cystitis, the results are as follows. Methods & Results : All patients were treated by the same method. Treatment was performed by means of Hapgokja(合谷刺, The needle arrived to the bladder wall) with electroacupuncture(electric stimulation was 5mA mixed pulse, low frequency 2Hz and high frequency 30Hz, intensity was adjusted to inside the scope where the patients perseveres.) The electrodes were placed CV2 to CV3, both K11, K12. Conclusions : 1. As the result, uses the Hapgokja(合谷刺), with the electroacupuncture, symptoms are remarkably improved and got the satisfactory effect in the treatment. 2. In Hunner's ulcer type, the first treatment was not satisfactory, and second time, after 15 times treatment, there were maintain urgency, 8 times nocturia, 70 percents bladder pain. 3. 3 patients of nonulcer type were treated for 44.8 times(average) and improved started after 5 times treatment. After 2 month's treatment, there were no frequency, no urgency, and remain 1 or 2 nocturia, 30 percents bladder pain.

• Childhood Kidney Diseases
• /
• 제16권2호
• /
• pp.146-149
• /
• 2012

평소 건강했던 아이들에서 육안적 혈뇨는 드물게 나타나며, 수신증과 동반된 경우 또한 드물다. 3세 남아가 육안적 혈뇨와 배뇨통을 주소로 내원하였다. 소변검사에서 농뇨, 혈뇨 보였으나 소변 배양 검사에서 균이 배양되지 않았으며, 혈액검사와 신체 검진상에서는 특이 소견 관찰되지 않았다. 초음파 검사상 양쪽 수신증과 함께 방광 벽이 두꺼워진 소견 보였다. 배뇨 요도 방광 조영술상 방광 요관 역류는 관찰되지 않았으나 방광 벽 비후가 심했으며, 방광 용적이 줄어들고 모양이 찌그러져있었다. 진단 후 ceftriaxone을 2주간 치료하였다. 항생제 치료 일주일 후 혈뇨 소실되어 초음파 검사를 다시 시행하였고 양쪽 수신증의 호전과 방광 용적 및 모양이 정상으로 호전됨을 관찰하였다. 환아의 배뇨통 증상도 호전되어 퇴원하였다. 외래 추적 관찰 중에 역류 검사 재 시행하였으며 정상 소견 보였다. 육안적 혈뇨 및 현미경적 혈뇨는 더 이상 관찰되지 않았다. 본 저자들은 육안적 혈뇨를 보인 소아에서 양측성 수신증을 동반한 방광염 1례를 경험하여 보고하는 바이다.

• 동의생리병리학회지
• /
• 제19권2호
• /
• pp.429-433
• /
• 2005

We investigated the effects of aqueous extract from talc for suppression in the process of cyclophosphamide-induced cystitis in the rat. The weight of urinary bladder was increased in the cyclophosphamide-injected rat compared with normal, but the increase of weight was arrested by intake of talc. More similar results showed in the uric test involving nitrate content and blood cell number and serum analysis involving the content of blood urea nitrogen and uric acid in the talc challenged rat compared with control one. More severe histological changes of urinary bladder such as edema, wall thickness, bleeding, vacuolation in mucosal epithelium were demonstrated in the rat injected with cyclophosphamide compared with normal. Fewer scores of these changes such as edema and bleeding were observed in rats treated with talc. In the immunohistochemical analysis, the expression of inflammatory-related protein examined tended to increase in the urinary bladder of cyclophosphamide-injected rat, especially COX-2 and $TNF-{\alpha}$ in mucosal epithelium and iNOS and $IL-1{\beta}$ in mucosal and muscular layer. The decline of these immunoreation were observed in the talc treated rat, significant decrease of COX-2 was detected in mucosal epithelium and iNOS in submucosal layer. These results suggest that talc may use as a useful therapeutic agent for noninfectious cystitis.