• Title/Summary/Keyword: Cyclic signal

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Preliminary evaluation of new 68Ga-labeled cyclic RGD peptides by PET imaging

  • Shin, Un Chol;Jung, Ki-Hye;Lee, Ji Woong;Lee, Kyo Chul;Lee, Yong Jin;Park, Ji-Ae;Kim, Jung Young;Kang, Joo Hyun;An, Gwang Il;Ryu, Young Hoon;Choi, Jae Yong;Kim, Kyeong Min
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.2 no.2
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    • pp.118-122
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    • 2016
  • Integrin ${\alpha}_v{\beta}_3$ plays an important role in the tumor metastases and angiogenesis. Arginine-glycine-aspartate (RGD) peptide motif binds to the integrin ${\alpha}_v{\beta}_3$. General $^{68}Ga$-labeled cyclic RGD peptides was rapidly eliminated from the circulatory system by renal excretion because of its hydrophilic property. The purpose of this study was to develop a novel $^{68}Ga$-labeled cyclic RGD peptides, which could acquire enhanced PET tumor images with improved pharmacokinetics by adopting biphenyl group between chelator and RGD peptides. $^{68}Ga$-DOTA-2P-c(RGDyK) was demonstrated a 12% higher lipophilicity level than $^{68}Ga$-DOTA-c(RGDyK) as a reference compound. In the animal PET, $^{68}Ga$-DOTA-2P-c(RGDyK) represented relatively lower blood-clearance, and an increased signal to noise ratio compared to $^{68}Ga$-DOTA-c(RGDyK). From these perspective, $^{68}Ga$-DOTA-2P-c(RGDyK) could be a good candidate for in integrin ${\alpha}_v{\beta}_3$-expressed tumor imaging.

A Study on the Electrochemical Deposition and p-Type Doping of ZnTe Films as a Back Contact Material for CdTe Photovoltaic Solar Cells (CdTe계 태양전지에 응용되는 ZnTe 박막의 전기화학적 제조 및 Cu 도핑 연구)

  • Kim, Dong-Hwan;Jeon, Yong-Seok;Kim, Gang-Jin
    • Korean Journal of Materials Research
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    • v.7 no.10
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    • pp.856-862
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    • 1997
  • 박막형 CdTe/CdS 태양전지의 배면전극(back contacts)물질로서 Cu도핑된 ZnTe 박막(ZnTe:Cu)을 전착법(electroplating)으로 제조하는 연구를 수행하였다. Sulfate계의 전해질 수용액에서 CdTe 기판과 투명전극으로 코팅된 유리(In$_{2}$O$_{3}$: Sn, ITO)기판 위에 ZnTe 박막을 코팅하는 방법으로써 potentiostat와 기판(cathode), Pt counter electrode, Ag/AgCI 표준전극으로 구성된 장치를 사용하여 pH=2.5-4, T=70-8$0^{\circ}C$, 0.02M $Zn^{2+}$ 1x$10^{-4}$M TeO$_{2}$, 0.2M $K_{2}$SO$_{4}$조건에서 -0.800 Vs~-0.975 V 범위의 전압(V$_{a}$ )에 걸쳐 실험하였다. ITO박막을 기판으로 사용하여 cyclic voltammogram을 작성한 결과 약 -0.50 V 에서 Te환원 peak이 나타났다. Auger electron spectroscopy (AES)로 조성분석한 결과 표면에서 Zn signal이 강하게 나왔고 시편의 두께에 따라 Zn의 signal감소하는 반면 Cd signal은 증가하는 것이 확인되었다. SEM 사진으로부터 ZnTe의 표면이 작은 입자 (0.2$\mu\textrm{m}$ 이하)로 구성되어 있으며 낮은 V$_{a}$ 에서는 입자가 작아지면서 조직이 치밀해짐이 관찰되었다. Optical transmission방법에 의하여 ITO기판위에 입혀진 박막의 밴드갭은 2.5 eV으로 측정되었다. 수용액중의 Cu$_{2+}$와 triethanolamine(TEA)은 산성용액에서 착물형성이 이루어지지 않았으며 1,10-phenanthroline과는 pH=2에서도 착물이 형성되었다.

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Performance Analysis of MC-DS-CDMA System Using a Interference Suppression Method in a Multipath Fading Channel (다중 경로 페이딩 채널 환경에서 다중반송파 DS-CDMA 시스템의 간섭 제거 성능 분석)

  • Park Tae-Yoon;Choi Jae-Ho
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.27 no.8B
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    • pp.745-751
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    • 2002
  • The performance of existing CDMA-type multiple access data transmission systems is limited by interferences due to adverse mobile communication channel characteristics. Among them, the multi-user interference becomes one of the major performance degradation factors because the signal-to-signal orthogonality can be easily perturbed when numerous user signals are distorted by multipath fading channels and mixed together. In order to enhance the performance of CDMA-type systems by suppressing the multi-user interference, we have adopted chip-based cyclic prefix insertion along with adaptive one-tap DFE equalization into MC-DS-CDMA, which is known for its robustness in the frequency selective multipath fading channel environment. In order to assess the performance of the proposed system, a set of computer simulations is performed in the reverse link in which each user signal undergoes different multipath Rayleigh fading. The results show us a superior performance of our system over other CDMA systems in terms of SNR to BER measurements.

Design and Performance Evaluation of Signal Processing for OFDM Underwater Acoustic Communications (OFDM 수중음향통신 신호처리 설계와 성능평가)

  • Kim Byung-Chul;Lu I-Tai
    • Proceedings of the Acoustical Society of Korea Conference
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    • autumn
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    • pp.487-490
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    • 2004
  • OFDM(Orthogonal Frequency Division Multiplexing) 방식의 수중음향 데이터 통신시스템에서 도플러 편이(Doppler Shift)와 도플러 확산(Doppler Spread)의 영향을 완화하여 주파수 효율을 향상시킬 수 있는 수신신호처리 방안을 설계하고 해상에서 송수신 된 시험 데이터의 BER 로써 성능을 평가한다. 도플러 편이를 OFDM 심볼에 부가된 Cyclic Prefix 와 상관계수법을 통해 추정하였으며 도플러 확산에 의해 시간에 따라 변화하는 채널을 Time-Frequency 축상에서 $2\times1D$ MMSE 방식으로 추정한다. 해상실험 결과, $8kHz\~11kHz$ 의 전송대역을 사용 할 때 복호 전 전송률 3098bps, 송수신 소자간 거리 7km, SNR 15dB에서 약 $1\~3\%$의 BER이 추정된다.

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Induction of penile erection in spinal cord-injured rabbits by administration of DA- 8159, a new selective PDE 5 inhibitor

  • Ahn, Gook-Jun;Kang, Kyung-Koo;Back, Dae-Hyun;Sohn, Yong-Sung;Choi, Seul-Min;Ahn, Byung-Ok;Kwon, Jong-Won;Kim, Won-Bae
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.250.2-251
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    • 2002
  • DA-8159 is a new. highly selective. potent cyclic-GMP phosphodiesterase 5 inhibitor developed by Dong-A Pharmaceutical Company(Kyunggi, Korea) as an oral drug for the treatment of erectile dysfunction. NO- cGMP signal transduction pathway plays a key role for relaxation of corpus cavernosal smooth muscle. In this study. the efficacy of DA-8159 was evaluated by measuring the length of uncovered penile mucosa in spinal cord injury(SCI) rabbits. (omitted)

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Pilot-symbol-aided channel estimation for the polyphae filter-based OFDM transmission system (다상 필터 기반 OFDM 전송 시스템을 위한 파일럿 채널 추정 기법)

  • Heo, Jin;Yoo, Kyung-Yul
    • Proceedings of the KIEE Conference
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    • 2004.07d
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    • pp.2610-2612
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    • 2004
  • The polyphase filter-based orthogonal frequency division multiplexing (PF-OFDM) is proposed in [1]. It provides more efficient data transmission mechanism than the classical OFDM method. However, the channel estimation mechanism in the classical OFDM system such as the cyclic prefix can not be applied straightforwardly, since the received signal contains unpredictable terms. Therefore, the PF-OFDM system requires a complicated channel estimation scheme when it works on the multipath fading communication channel. In this paper, we proposed a pilot-symbol aided channel estimation algorithm suitable for the PF-OFDM system which efficiently deals with the unpredictable terms and verified its performance through a series of computer simulations.

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Structural Elucidation and Antimicrobial Activity of an Antibiotic, Echinomycin, Produced by Actinomycetes KGT-37 (Actinomycetes KGT-37 균주가 생산하는 항생물질 Echinomycin의 구조해석 및 항균활성)

  • 여운형;김영호;윤봉식;박은경
    • Korean Journal Plant Pathology
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    • v.12 no.3
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    • pp.302-306
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    • 1996
  • 항균물질을 생산하는 방선균 KGT-37를 인삼밭 토양에서 분리하여 배양액으로부터 항균물질을 분리하고 silica gel column chromatography, preparative TLC, HPLC로 정제하였다. \ulcornerH-\ulcornerH COSY, HMQC, HMBC등 NMR 분석결과 KGT-37이 생산하는 항균물질은 cyclic depsipeptide계의 항생물질인 echinomycin으로 동정되었으며 이 연구에서 지금까지 assign되지 않았던 \ulcornerH과\ulcornerC의 NMR signal이 완전히 assign되었다. 이 항균활성물질은 감자더뎅이병균인 Streptomyces scabies과 Corynebacterium lilium을 포함하는 그람 양성 세균에 특히 강한 항균활성을 보였으며, 도열병균 및 점무늬낙엽병균 등 병원곰팡이에도 항균활성을 나타내었다.

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Design of a Remote Lighting Control System Using Time Division Multiplex Transmission (시분할 다중 전송방식을 이용한 원격 조명제어 설계)

  • 정성재;김일환
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.33-33
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    • 2000
  • In this paper a new distributive control system for BA(Building Automation ) lighting control used on general microprocessors is presented. For optimal lighting control and saving energy, The system have to control the group and pattern lighting control as well as individual light control at one time. Tn this paper, This functions are accomplished with low-cost and simple microprocessor. A plurality of modulated light control terminals are connected to the central control unit through a pair of power line. This power line provide both power and signal to the each terminal and the data is transmitted through cyclic time division multiplex transmission. With this structure a low-cost distributive control system for lighting applications has been achieved, allowing energy and maintenance saving and reliability increase of the light control system.

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Real- time Precise Positioning Algorithm with Float Ambiguity and Performance Analysis (실수 미지정수를 이용한 실시간 정밀위치 결정기법 및 성능분석)

  • 이영식;지규인;한훈택
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.51-51
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    • 2000
  • The ambiguity resolution is an essential task for the precise carrier phase differential GPS. In practice, however, there are still many problems in resolving the ambiguity in kinematic mode, especially in the urban areas. The multipath in received signal, the frequent change in visible satellites, and the cyclic slips make the ambiguity resolution very difficult task in real-time operation. In this paper, we consider a differential positioning with the float ambiguity that is free from the integer constraint. The float ambiguity estimation if carried out by the Kalman filter. The float and fixed ambiguities are combined together to determine the position in real-time kinematic mode.

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Fast Carrier Frequency Synchronization for CMMB Robust to Time Offset and Fading (시간 오프셋 및 페이딩 환경에 강인한 CMMB 고속 주파수 동기 알고리듬)

  • Kang, Eun-Su;Han, Dong-Seog
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.35 no.6C
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    • pp.516-522
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    • 2010
  • In this paper, the carrier frequency offset estimator is proposed for the China multimedia mobile broadcasting (CMMB). The fractional carrier frequency offset is estimated by utilizing the cyclic prefix in each CMMB symbol. In addition, the integer carrier frequency offset can be estimated with the synchronization signal in every CMMB frame. The proposed estimator is the most suitable for the frame structure of CMMB. It shows a prominent performance even in timing offset and multipath conditions.