• 제목/요약/키워드: Cycle-by-cycle variation

검색결과 553건 처리시간 0.029초

정상배란성 월경주기에서 혈청 인슐린유사 성장인자 결합단백질의 양상 (Serum Insulin-like Growth Factor Binding Proteins Profiles During the Normal Oulatory Menstrual Cycle)

  • 정재훈;김정구
    • Clinical and Experimental Reproductive Medicine
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    • 제26권1호
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    • pp.67-73
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    • 1999
  • The insulin-like growth factor (IGF)s are believed to one of several growth factors that play an adjunctive role in ovarian follicular development. These factors circulate bound to a family of IGF-binding protein (IGFBP)s. It is known that circulating IGFBPs are involved in the transport of IGFs to tissues and modulate IGFs actions at local tissue. The purposes of this study were to evaluate changes in serum IGFBPs profiles during normal ovulatory menstrual cylce and to compare serum IGFBPs profiles in periovulatory phase of between normal ovulatory menstrual cylce and controlled hyperstimulated cycle. Fasting blood samples were obtained from 15 normal healthy women throughout normal ovulatory menstural cyle and on the day of aspiration of oocyte from 10 patients undergoing ovarian hyperstimuation for in vito fertilization-embryo transfer. Serum IGFBP-1 - IGFBP-4 were measured by western ligand blot and immunoprecipitation. Serum $17{\beta}$-estradiol was determined by radioimmunoassay. Type and molecular weight of serum IGFBP did not changed during normal ovulatory menstural cycle. No significant variation in the relative proportion and level of each IGFBP was found throughout normal ovulatory menstural cyle. Also, the relative proportion and level of each IGFBP did not correlated with serum $17{\beta}$-estradiol level. There was no significant difference in the relative proportion and level of each serum IGFBP between on the day of ovulation in normal ovulatory menstrual cylce and on the day of aspiration of oocyte in controlled hyperstimulated cycle. Our data indicate that IGFBPs have regulatory functions in ovary through an paracrine and autocrine rather than endocrine mechanism during normal ovulatory menstural cycle.

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연속회분식 공정에서 COD부하에 따른 질산화/탈질율 및 유출질소 분휴 (Nitrification/Denitrification Rate and Classification of Output Nitrogen according to COD Loads in SBR)

  • 이재근;임수빈
    • 한국물환경학회지
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    • 제24권1호
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    • pp.30-35
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    • 2008
  • In this study, we investigated the nitrification/denitrification rate and classification of output nitrogen of a sequencing batch reactor (SBR) system with the variation of COD loads ; COD loads of 0.3, 0.4, 0.6, 0.7, 0.8, 1.0 and $1.2kgCOD/m^3{\cdot}d$ were tested to determine the optimum conditions for the operation of the SBR and increase its nitrogen removal efficiency. As the COD loads increased, the nitrification rate at aerobic(I) period and the denitrification rate at anoxic(I) period were decreased. With the variation of COD loads, the amounts of nitrogen removed in the clarified water effluent were 63.9, 54.2, 34.7, 22.5, 13.7, 12.5 and 26.5 mg/cycle, respectively. The amounts of nitrogen removed during the sludge waste process were 19.5, 26.6, 41.0, 47.3, 58.1, 72.4 and 88.1 mg/cycle, respectively. The amounts of nitrogen removed by denitrification were 66.8, 69.3, 68.9, 56.5, 39.5, 7.3 and 0.0 mg/cycle, respectively, indicating that COD load more than $0.7kgCOD/m^3{\cdot}d$ decreases the amounts of denitrified nitrogen. The nitrogen mass balances were calculated as the percentages of nitrogen removed in the clarified water effluent or by denitrification and sludge waste processing in each cycle of SBR operation and were 99.0, 98.5, 95.4, 82.1, 73.0, 60.5 and 74.8% for COD loads of 0.3, 0.4, 0.6, 0.7, 0.8, 1.0 and $1.2kgCOD/m^3{\cdot}d$, respectively.

PWR환경을 모사한 저주기 피로실험장치 국산화 (Development of Low-Cycle Fatigue Test Rig in Simulated PWR Environments)

  • 정일석;김상재;이용성;홍승열
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2004년도 추계학술대회
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    • pp.178-183
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    • 2004
  • For developing fatigue design curve of cast stainless steels that would be used in piping material of domestic nuclear power plants, a low-cycle fatigue test rig was built. It is capable of performing tests in pressurized high temperature water environment of PWR. Cylindrical specimens of CF8M were used for the strain-controlled environmental fatigue tests. Fatigue life was measured in terms of the number of cycles with the variation of strain amplitude at 0.04%/s strain rates. The disparity between target length and measured length of specimens was corrected by using finite element method. The corrected test results showed similar fatigue life trend with another previous results.

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낙동강 하구의 조석변화에 따른 Heterotrophic Activity의 계절적 변화와 염분의 영향 (Seasonal Variation of Heterotrophic Activity in the Estuary of Naktong River over Half Tidal Cycle and Salinity Effect)

  • 안태영;박중찬;하영칠
    • 미생물학회지
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    • 제29권5호
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    • pp.339-343
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    • 1991
  • Heterotrophic activity, total bacteria and salinity were determined seasonally in the estuary of Naktong River over half tidal cycle. Heterotrophic activity was determined by the uptake of [U- $^{14}$ C]glucose. Heterotrophic activity fluctuated with the tides and was decreased as salinity increased. Teh great activity occurred near low ebb tide at all seasons except summer. The main environmental factor affecting hetreotrophic activity was the salinity rather than water temperature in the estuary of Naktong River. In order to estimate the effect of salt, salt was added to estuarine water. Vmax for glucose of salt-added water was 17% and 77% of original estuarine water at station 1 and 2 respectively and slight increase was observed at station 3. Respiration rate and Kt+Sn for glucose of salt-added sample increased at all 3 stations. The increase of the Kt value implies the reduced affinity of bacterial population for glucose. The effects of salinity on the heterotrophic activity were more extensive in the upper region of estuary than at the mouth.

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복합 사이클의 배기가스 열회수 시스템에 의한 선박용 디젤엔진의 연료 절약에 관한 이론적 연구 (Theoretical Study on Fuel Savings of Marine Diesel Engine by Exhaust-Gas Heat-Recovery System of Combined Cycle)

  • 최병철;김영민
    • 대한기계학회논문집B
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    • 제37권2호
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    • pp.171-179
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    • 2013
  • 선박의 주 추진용 디젤엔진으로부터 배출되는 배기가스의 열을 회수하는 폐열회수 발전시스템에 대하여, 상대적으로 고온에 상부의 3 변 사이클과 상대적으로 저온부에 하부의 유기 랭킨 사이클이 적용되는 복합 사이클에 대한 열역학적 특성을 조사하였다. 그 결과, 상부와 하부 사이클 사이에 경계온도의 증가에 따라, 총 파괴된 엑서지율(${\sum}\dot{E}_d$) 및 엑서지 손실율($\dot{E}_{out2}$)이 각각 감소되었기 때문에, 시스템의 에너지 및 엑서지 효율이 모두 최대화되었다. 그리고 상부의 체적 팽창비가 크게 감소되었다. 그 경우에 대하여, 부가적인 추진동력으로써 활용되는 폐열회수 발전시스템이 적용된 선박용 디젤엔진의 경우에, 추진 효율은 엔진부하 변동에 따라 기본 엔진에 대비하여 평균적으로 9.17 %가 향상되었다. 이에 대하여, 디젤엔진의 연료 소비율과 이산화탄소 배출률은 각각 평균 8.4 및 8.37 %가 저감되었다.

홍합, Mytilus coruscus의 성 성숙과 생식주기 (Sexual Maturation and Gametogenic Cycle of the Hard Shelled Mussel, Mytilus coruscus (Bivalvia: Mytilidae))

  • 위종환;장영진;이승주;허영백;이정식
    • 한국양식학회지
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    • 제16권4호
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    • pp.245-251
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    • 2003
  • 2000년 1월부터 12월까지 남해안 한산만 해역에서 채집한 홍합의 생식소 발달과 생식주기에 관하여 조직학적 방법을 이용하여 조사하였다. 홍합은 자웅이체이며, 생식소는 암 수 모두 다수의 배우자형성소낭으로 이루어져 있었다. 생식소지수(GI)는 2월(3.40)에 가장 높았으며, 8월(1.18)에 가장 낮았다. 비만도(CI)는 생식소지수(GI)와 유사하게 변화하였다. 홍합의 주 산란기는 2∼3월이며, 생식주기는 휴지기(8∼11월), 분열증식기(11∼12월), 성장기(12∼1월), 성숙기(1∼2월), 부분방출기(2∼4월), 완전방출 및 퇴화흡수기(4∼7월)로 구분할 수 있었다. 성비(암:수)는 1:0.96으로 조사되었다.

2행정 디젤엔진의 소기압력이 사이클변동에 미치는 영향에 관한 연구 (A Study on the Effect of Cycle Variation on Scavenging pressure in 2-Stroke Diesel Engine)

  • 윤창식;김치원;김기복
    • 한국산업융합학회 논문집
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    • 제19권3호
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    • pp.154-159
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    • 2016
  • Recently it has been focused that the automobile engine has developed in a strong upward tendency for the use of the high viscosity and poorer quality fuels in achieving the high performance, fuel economy, and emission reduction. Therefore it is not easy to solve the problems between low specific fuel consumption, and exhaust emission control at automotive engine In this study, it is designed and used the test bed which is installed with fuel injector controller. In addition to equipped engine using CRDI by controlling the injection timing with modulator, it has tested and analyzed the engine cycle variation characteristics, as it is varied that they are the operating parameters: fuel injected quantity, injection timing, engine speed and scavenging pressure.

슈퍼 듀플렉스 스테인리스강 다층용접부의 미세조직 및 공식(Pitting Corrosion)에 미치는 용접열사이클의 영향 (Effect of Welding Thermal Cycle on Microstructure and Pitting Corrosion Property of Multi-pass Weldment of Super-duplex Stainless Steel)

  • 남성길;박세진;나혜성;강정윤
    • Journal of Welding and Joining
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    • 제28권4호
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    • pp.18-25
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    • 2010
  • Super-duplex stainless steels (SDSS) have a good balance of mechanical property and corrosion resistance when they consist of approximately equal amount of austenite and ferrite. The SDSS needs to avoid the detrimental phases such as sigma(${\sigma}$), chi(${\chi}$), secondary austenite(${\gamma}2$), chromium carbide & nitride and to maintain the ratio of ferrite & austenite phase as well known. However, the effects of the subsequent weld thermal cycle were seldom experimentally studied on the micro-structural variation of weldment & pitting corrosion property. Therefore, the present study investigated the effect of the subsequent thermal cycle on the change of weld microstructure and pitting corrosion property at $40^{\circ}C$. The thermal history of root side was measured experimentally and the change of microstructure of weld root & the weight loss by pitting corrosion test were observed as a function of the thermal cycle of each weld layer. The ferrite contents of root weld were reduced with the subsequent weld thermal cycles. The pitting corrosion was occurred in the weld root region in case of the all pitted specimen & in the middle weld layer in some cases. And the weight loss by pitting corrosion was increased in proportional to the time exposed at high temperature of the root weld and also by the decrease of ferrite content. The subsequent weld thermal cycles destroy the phase balance of ferrite & austenite at the root weld. Conclusively, It is thought that as the more subsequent welds were added, the more the phase balance of ferrite & austenite was deviated from equality, therefore the pitting corrosion property was deteriorated by galvanic effect of the two phases and the increase of 2nd phases & grain boundary energy.

고속 PLL을 위한 이중구조 PFD ((A Dual Type PFD for High Speed PLL))

  • 조정환;정정화
    • 대한전자공학회논문지TE
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    • 제39권1호
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    • pp.16-21
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    • 2002
  • 본 논문에서는 TSPC(True Single Phase Clocking) CMOS 회로를 이용하여 출력특성을 향상시킨 고속 PLL을 위한 이중구조 PFD(Phase Frequency Detector)를 제안한다. 넓은 dead zone과 긴 지연시간을 갖고 있는 기존의 3-state PFD는 고속 동작에 사용되는 PLL(Phase-Locked Loop)에서 사용하는 것은 부적합하다. 이러한 3-state PFD의 단점을 해결하기 위하여 다이내믹 CMOS 논리회로로 구현된 다이내믹 PFD는 duty cycle의 변화에 따라 지터 잡음을 발생하는 문제점을 갖는다. 이러한 문제를 해결하기 위하여 TSPC 회로와 이중구조를 갖도록 설계되어 제안된 PFD는 dead zone과 duty cycle의 제한조건을 개선하였고, 지터잡음과 응답특성을 개선하였다. 즉, 이중구조를 갖는 PFD는 상승에지에서 동작하는 P-PFD(Positive edge triggered PFD)와 하강에지에서 동작하는 N-PFD(Negative edge triggered PFD)로 구성하여 이득을 증가시켜 응답특성을 개선한다. 제한된 내용의 입증을 위하여 Hspice 시뮬레이션을 수행하였다. 제안된 PFD는 dead zone이 존재하지 않으며, duty cycle의 변화에도 안정된 결과를 나타내며 응답특성이 우수함을 확인할 수 있었다.

Micronesia Chuuk Island에 서식하는 Top shell, Trochus niloticus의 생식주기 (Reproductive Cycle of Top Shell, Trochus niloticus in Chuuk Island, Micronesia)

  • 진영석;박용주;김한준;나오수;송영보;이치훈;최면식;노섬;이영돈
    • 한국패류학회지
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    • 제20권1호
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    • pp.65-73
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    • 2004
  • Gametogenesis, changes of gonad bulk index (GBI), monthly variation in oocyte diameter, reproductive cycle and spawning with lunar cycle of the top shell, Trochus niloticus were investigated by histological examination. The specimens were sampled in the coastal waters of Chuuk Island, Micronesia, form November 1999 to September 2000. T. niloticus is a gonochorism, and the female and male were present in an approximately 1:1 ratio (p > 0.05). The ovary contained with the oocyte of yolk stage, the testis composed of the spermatid and spermatozoa at around the year. Monthly GBI were higher at February, March, April and June than the other months. Major spawning occurred between April and May, and June and July but the individuals of partially spawning were presented throughout the year. GBI with lunar cycle were higher at the full moon than the other lunar phase. These results suggest that the spawning occurred between the full moon and last quarter moon.

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