• 사물인터넷융복합논문지
• /
• 제9권3호
• /
• pp.61-67
• /
• 2023

구리의 전기주조 공정을 최적화하기 위하여 이중 비밀 다층구조의 역전파 뉴럴 네트워크가 구성된다. 샘플 학습을 통하여, 구리 전기주조 공정 조건과 목표 특성 간의 함수관계가 정확히 성취되고, 구리 전기주조 공정 내에서 다층구조의 미세강도와 장력에 대한 예측이 이루어진다. 예측된 결과는 펄스 전원공급기를 장착한 구리 피로인산염 솔루션 시스템 내에서 구리의 전해석출 시험에 의하여 증명된다. 그 결과는 다음과 같이 나타난다. "3-4-3-2" 구조의 이중비밀 다층구조 뉴럴 네트워크에 의하여 예측된 구리 다층구조의 미세강도와 장력은 실험값에 매우 근접하며 그 상대적 오차는 2.32%보다 작다. 주어진 파라미터의 범위 내에서, 구리의 미세강도는 100.3~205.6MPa이며, 장력은 112~485MPa 정도로 측정된다. 미세강도와 장력이 최적인 조건에서 그에 대응하는 공정 조건은 다음과 같다: 전류밀도는 2A·dm-2, 펄스 주파수는 2KHz, 펄스의 듀티싸이클은 10%이다.

• BMB Reports
• /
• 제56권5호
• /
• pp.265-274
• /
• 2023

Defects in DNA double-strand break (DSB) repair signaling permit cancer cells to accumulate genomic alterations that confer their aggressive phenotype. Nevertheless, tumors depend on residual DNA repair abilities to survive the DNA damage induced by genotoxic stress. This is why only isolated DNA repair signaling is inactivated in cancer cells. DNA DSB repair signaling contributes to general mechanism for various types of lesions in diverse cell cycle phases. DNA DSB repair genes are frequently mutated and amplified in cancer; however, limited data exist regarding the overall genomic prospect and functional result of these modifications. We list the DNA repair genes and related E3 ligases. Mutation and expression frequencies of these genes were analyzed in COSMIC and TCGA. The 11 genes with a high frequency of mutation differed between cancers, and mutations in many DNA DSB repair E3 ligase genes were related to a higher total mutation burden. DNA DSB repair E3 ligase genes are involved in tumor suppressive or oncogenic functions, such as RNF168 and FBXW7, by assisting the functionality of these genomic alterations. DNA damage response-related E3 ligases, such as RNF168, FBXW7, and HERC2, were generated with more than 10% mutation in several cancer cells. This study provides a broad list of candidate genes as potential biomarkers for genomic instability and novel therapeutic targets in cancer. As a DSB related proteins considerably appear the possibilities for targeting DNA repair defective tumors or hyperactive DNA repair tumors. Based on recent research, we describe the relationship between unstable DSB repairs and DSB-related E3 ligases.

• 치위생과학회지
• /
• 제23권4호
• /
• pp.302-311
• /
• 2023

Background: Oral health is an important element of well aging. And oral health also affects overall health, mental health, and quality of life. In this study, we sought to identify oral health influencing factors and research trends for well-aging through text analysis of research on well-aging and oral health over the past 12 years. Methods: The research data was analyzed based on English literature published in PubMed from 2012 to 2023. Aging well and oral health were used as search terms, and 115 final papers were selected. Network text analysis included keyword frequency analysis, centrality analysis, and cohesion structure analysis using the Net-Miner 4.0 program. Results: Excluding general characteristics, the most frequent keywords in 115 articles, 520 keywords (Mesh terms) were psychology, dental prosthesis and Alzheimer's disease, Dental caries, cognition, cognitive dysfunction, and bacteria. Research keywords with high degree centrality were Dental caries (0.864), Quality of life (0.833), Tooth loss (0.818), Health status (0.727), and Life expectancy (0.712). As a result of community analysis, it consisted of 4 groups. Group 1 consisted of chewing and nutrition, Group 2 consisted oral diseases, systemic diseases and management, Group 3 consisted oral health and mental health, Group 4 consisted oral frailty symptoms and quality of life. Conclusion: In an aging society, oral dysfunction affects mental health and quality of life. Preventing oral diseases for well-aging can have a positive impact on mental health and quality of life. Therefore, efforts are needed to prevent oral frailty in a super-aging society by developing and educating systematic oral care programs for each life cycle.

• 농촌계획
• /
• 제29권4호
• /
• pp.69-79
• /
• 2023

This study investigated changes in the spatial structure of rural villages in Sayang Village, where accessibility restrictions to island areas were improved, and analyzed the spatial composition of houses according to changes in the living environment. First, despite the island's vulnerable transportation requirements being resolved by the completion of the land and bridge in 2018, the local economy continues to stagnate due to a vicious cycle of local living services and job losses. Second, when a survey of residents' changed living services was conducted through the continuation of the specification map, the scope of living areas was expanded by analyzing the frequency and place of visit of fresh food purchases, use of convenience facilities, and medical visits. Third, it is judged that the naturally formed village is composed of small roads to the inside of the village due to the disorganized street system and the form of walking instead of vehicles. Finally, as a result of analyzing the residential space of houses in fishing villages, the aging rate of houses over 30 years old was 62 (91.2%), and the average area of the first house space built was 65.2m² to 14.1m², an increase of 17.8% of the total area.

• 한국전자통신학회논문지
• /
• 제18권5호
• /
• pp.841-852
• /
• 2023

국내 전력계통의 주파수 조정용 발전기로 사용되고 있는 가스터빈은 탄소중립 정책과 더불어 신속한 기동·정지 및 높은 열효율 등으로 인해 이용률이 증가하고 있다. 가스터빈은 고온의 화염을 이용하여 터빈을 회전시키기 때문에 터빈 입구온도가 기기의 성능과 수명을 좌우하는 핵심요소로 작용하고 있다. 하지만 입구온도는 직접적인 측정이 불가능함에 따라 제작사가 산출한 온도를 이용하거나, 현장 경험을 토대로 하여 예측된 온도를 적용하고 있어서 가스터빈의 안정적인 운전 및 유지관리에 많은 어려움을 겪고 있다. 이에 본 연구에서는 인공신경망에서 많이 사용되고 있는 DNN(: Deep Neural Network) 기반으로 하는 재열 가스터빈의 입구온도를 예측할 수 있는 모델을 제시하고 실측 데이터를 기반으로 제안된 DNN의 성능을 검증하고자 한다.

• 한국건축시공학회지
• /
• 제24권3호
• /
• pp.363-370
• /
• 2024

기후 변화에 따른 자연재해와 이상기상의 빈도 및 심도가 날로 증가하면서, 사회기반시설과 건축물에 미치는 영향도 점차 커지고 있다. 이러한 문제에 대응하기 위해 다양한 정부 기관과 민간 부문에서는 이로인한 피해를 정확히 평가하려는 노력을 기울이고 있지만, 현실에 부합하는 정밀한 피해 예측과 평가는 여전히 도전적인 과제로 남아 있으며, 현재의 기술 수준으로는 부족함이 많다. 이러한 배경 하에, 본 연구는 우리나라에서 발생하는 주요 자연재해 중 하나인 태풍에 의한 건축물 피해를 분석하여, 해당 피해를 정확히 평가할 수 있는 방법론을 제시하고자 한다. 딥러닝 알고리즘을 활용한 평가 방식과 프레임워크를 도입하여, 태풍으로 인한 건물 피해 평가에 관한 연구를 진행하였다. 본 연구의 결과는 건물의 수명주기 전반에 걸친 자연재해 피해 평가에 필요한 기본 데이터를 제공하고, 다양한 산업 및 연구 영역에서 위험 평가에 활용이 가능하다.

• 기본간호학회지
• /
• 제7권3호
• /
• pp.415-428
• /
• 2000

The purpose of this study was to identify side effects of the vesicant chemotherapy. The study was designed to be a descriptive survey. The subjects of this study were 88 patients with various types of cancer, primary lung cancer(25.0%), advanced gastric cancer(25.0%), breast cancer(20.5%), etc. The mean age was 44.8 years old(range: 16-68). The questionnaire was completed by nurses of the outpatient unit and chemotherapy ward, and intravenous nurse specialist. The results of the study were as follows: 1) Chemotherapy was administered with a 23G scalp needle and 24G insyte. Injection site was dorsum of hands(64.7%), cephalic vein(19.3%). Successful rate for the first attempt was 88.6%. The first & second cycle chemotherapy was 29.5% each.. Mainly used drugs were Navelbine(34.1%), Adriamycin(20.5%). 2) Venous Problems after chemotherapy were pain(13.6%) incurred by venous, mainly due to the administration of Navelbine; redness at the inravenous site(12.5%) and itching sense 2.3% Non-venous problems were nausea (18.2%), dullness(14.8%), vomiting(8.0%), facial flushing(6.8%), anxiety(5.7%). Subjective discomforts after chemotherapy were generalized arm pain at the injection side(14.8%), dizziness(6.8%), weakness(5.7%) and general bodyache(5.7%). Systemic anaphylactic reaction and extravasation did not occur. 3) Non-venous problem after chemotherapy were nausea, vomiting & anorexia. Frequency of chemotherapy related to side effects were itching, facial flushing, and nausea(p< .05). Day of chemotherapy related to side effects were nausea & vomiting(p< .05). Site of chemotherapy related to side effects were redness(p< .05). Frequency of venipuncture related to side effects were redness(p< .05). Conclusively, cancer chemotherapy patients have had some venous problem. They need appropriate venous access devices for chemotherapy. And other non-venous problem will be managed appropriately. Further research was required to identify the rate of venous complication or side effects of vesicant chemotherapy.

• 마이크로전자및패키징학회지
• /
• 제24권3호
• /
• pp.71-76
• /
• 2017

열 소결 공정 중 소결 온도와 시간을 다르게 하여 제작된 은 인쇄회로의 전기적 거동과 유연성을 분석하였다. 은 인쇄회로의 비저항값과 고주파 전송 특성을 4-포인트 프로브 및 네트워크 분석기를 사용하여 각각 측정하였다. 비저항값은 DC 전류가 회로에 흐를 때의 전기 저항을, 고주파 전송 특성은 은 회로의 신호 전송 특성을 의미한다. 은 인쇄회로의 유연성은 IPC 슬라이딩 테스트 중 발생하는 회로 저항의 변화를 실시간으로 측정하여 평가하였다. 은 인쇄회로의 파괴 모드는 주사전자 현미경과 광학 현미경을 통해 관측하였다. 폴리이미드 기판 위에 인쇄된 은 회로의 비저항값은 소결 온도와 소결 시간이 증가함에 따라 급격하게 감소하였다. $250^{\circ}C$에서 45분간 열 소결된 은 인쇄회로의 비저항값이 가장 낮았으며 그 때의 값은 $3.8{\mu}{\Omega}{\cdot}cm$였다. 은 인쇄회로에서 발생한 균열은 슬라이딩 테스트 10만번 이후의 길이가 2.5만번 테스트 후의 균열보다 열 배는 더 길게 측정되었다. 측정된 전송계수와 반사계수는 전산모사 결과와 그 경향이 거의 일치하였으며 슬라이딩 테스트가 진행될수록 은 회로의 전송손실은 증가하였다.

• 자원리싸이클링
• /
• 제13권6호
• /
• pp.37-42
• /
• 2004

NiO, ZnO 조성이 다른 Ni-Cu-Zn 페라이트의 손실 분석을 실시했다. 손실, Ph는 측정 온도의 상승에 따라 감소해 100-120$^{\circ}C$ 근처에서 일정한 값을 얻었다. Pcv의 주파수의존성은 Pcv~f$^n$ 로 표현될 수 있는데, n은 1 MHz까지 일정했다. Pcv는 ZnO/NiO비가 증가함에 따라 감소한다. Pcv를 Hysteresis loss(Ph) 및 잔류손실(Pcv-Ph)로 분리했다. Pcv의 온도특성 및 조성 의존성은 Ph에 기인하지만, Pcv-Ph는 온도 및 조성에 의존하지 않는다. Ph와 초투자율, ${\mu}_i$의 온도 및 조성 의존성을 분석해, 다음과 같은 식이 성립된다는 것을 알 수 있었다. ${\mu}_i{\mu}_0=I_s^2/(K_I+b{\sigma}_0{\lambda}_s)$ Wh=13.5(I$_s^2/{\mu}_i{\mu}_0)$ 여기서, ${\mu}_0$은 진공의 투자율, I$_s$는 포화자화, K$_I$는 이방성상수, ${\sigma}_0$는 내부 불균일 응력, ${\lambda}_s$는 자기이방성 상수, b는 미지의 상수, Wh는 1주기 당의 히스테리시스 손실(Ph=Wh${\times}$f)이다. Ni-Cu-Zn 페라이트의 Steinmetz 상수 m=1.64~2.2는 Mn-Zn 페라이트보다는 적은데, 이는 양 재료 간의 손실 메커니즘의 차가 있음을 암시하는 것이다.

• 한국치위생학회지
• /
• 제12권2호
• /
• pp.399-407
• /
• 2012

Objectives : Purpose of this research is to determined the general knowledge on oral health and the usage of oral hygiene products in the orthodontic patients and try to provide an appropriate oral hygiene products for the patients. Methods : Orthodontic patients who visited a dental clinic in Daejeon were selected and data from 352 patients were collected. Questionnaire based on survey was conducted from 1st of March to 30th in 2011 and all the data was analysed by using SPSS statistical program (VER 15.0). Frequency analysis, $x^2$ test, T-test and the amount of diurnal variance analysis (one-way ANOVA) were also used. After that, scheffe's post-test method was conducted. Results : According to the general characteristics of oral health care knowledge score was $2.87{\pm}0.60$, the attitude score was $2.96{\pm}0.57$. toothbrush replacement cycle were less than 3 months (p=0.007, p=0.000) and frequency of brushing one day more than three times higher in patients with knowledge to help attitude. according to the sex, age, and duration of orthodontic treatment with oral hygiene devices of usage was higher in the calibration toothbrush usage, awareness was higher in the interdental toothbrushes. according to the type of orthodontic devices from the oral hygiene devices usage, removable group was the orthodontic toothbrush and electric toothbrush group were highest in the 'unknown', the fixed group was orthodontic toothbrush(67.3%) and electric toothbrushes(40.8%) was higher in the usage. Patients who used oral hygiene devices such as orthodontic tooth brush, interdental brush, electric toothbrush, water pik and fern solution showed wider knowledge on oral health care and oral hygiene devices compared to patients who answered as does not aware of oral hygiene devices and never used these products before. Conclusions : Orthodontic patient's oral health attitudes, knowledge, and oral hygiene devices usage are the general characteristics of the highest in the orthodontic toothbrush usage, awareness was higher in the interdental brush. Water pik and fern solution, rubber and gingival interdental stimulator turned massage does not use or low. Based on results from research, overall orthodontic patients who visited a dental clinic had low awareness and usage of oral hygiene devices. Therefore, it is required to educate general publics and the orthodontic patients and also promote the importance of usage of oral hygiene devices.