• YAKHAK HOEJI
• /
• v.39 no.6
• /
• pp.689-694
• /
• 1995

Sphingolipids play important roles in cell regulation and signal transduction. Recently, a sphinogomyelin cycle has been described in which activation of neutral sphingomyelinase leads to the breakdown of sphingomyelin and the generation of ceramide. Ceramide, in turn, has emerged as a candidate intracellular mediator for the action of certain cell agonists and has multiple biologic actions. Ceramide is a potent suppressor of cell growth and an inducer of apoptosis. The present studies show that exposure of IM-9 cells to ceramide resulted in internucleosomal cleavage of DNA, yielding laddered patterns of oligonucleosomal fragments characteristic of apoptosis. DNA fragmentation induced by ceramide was also confirmed by diphenylamine assay. The effect of ceramide on cell cycle progression was also studied. The addition of ceramide increase G$_{1}$ phase distribution in cell cycle. Cell cycle-related cyclin D$_{1}$ gene expression was decreased in a time-dependent manner. These results suggest that apoptosis induced by ceramide is related to cell cycle associated with the alteration of cell cycle in IM-9 cells.

• Proceedings of the KIEE Conference
• /
• 2002.07c
• /
• pp.1446-1448
• /
• 2002

The short-time permissible temperature of an overhead distribution line conductor is determined by the softening characteristics of ACSR-OC, ACSR AW/OC 160, typical conductors employed in the overhead distribution line. Transient heat transfer equation and Newton's cooling law were applied to analyze the heating and cooling effects of the insulating conductors, respectively, and the error of co-relation was calibrated after simulating the softening test to assess the short-time characteristic of the insulating conductor. In order to verify the softening characteristic, the conductors were tested with heat cycle. The test was totally carried out 200 cycles, and 1 cycle was to heat and cool at 1.1 times permissible current of the conductor, 1.15 times for 120 minutes, respectively. After heating, the tensile strength and surface of the conductor were observed. In case of ACSR-OC, as the result of 100 hour heating test, the tensile strength of the insulator was 0.8 times the initial value. This is equivalent to the value of the conductors which are used for 10 years at sites.

• 한국신재생에너지학회:학술대회논문집
• /
• 2009.11a
• /
• pp.528-532
• /
• 2009

Integrated Gasification Combined Cycle (IGCC) power plant converts coal to syngas, which is mainly composed with hydrogen and carbon monoxide, by the gasification process and produces electric power by the gas and steam turbine combined cycle power plant. The purpose of this study is to investigate the influence of gasification process to type and structure of gasifier. For this purpose, the performance characteristics of gasification reaction are analyzed with the operation characteristic of pilot-scale 2-stage coal gasifier. It is found that gasification reaction, floating characteristic of melted slag, particle stick of inside of the gasifier, particle stick and deposit of Syngas cooler are the causes in the different performance characteristics.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.33 no.2
• /
• pp.133-140
• /
• 2009

A fast-response $CO_2$ analyzer has been developed for measuring the $CO_2$ concentration during transient condition of a SI engine. The analyzer consists of the non-dispersive infrared absorption method, electrical chopping system and water cooling system. The analyzer has good repeatability, linearity and permissible drift characteristic. Besides, it showed 18ms of a response to measure the $CO_2$ concentration. The fast-response $CO_2$ analyzer was applied to a single cylinder SI engine and the $CO_2$ emission was examined during engine start. Simultaneously, the standard exhaust gas analyzer, which has slow response time, was used for confirming the accuracy of the exhaust gas analysis using the fast-response $CO_2$ analyzer. The developed analyzer showed much faster responsive characteristic than that of a standard analyzer and made cycle by cycle exhaust gas analysis possible. The transient engine operating characteristics will be estimated from the $CO_2$ concentration of engine-out emissions and engine operating variables.

• Journal of Embryo Transfer
• /
• v.31 no.3
• /
• pp.307-311
• /
• 2016

The aim of this study was to compare the appearance rate of vaginal cytology during estrous cycle in small pet bitches. A characteristic features of vaginal cytology during the estrous cycle were the high proportion of superficial cell in proestrus, anuclear cell in estrus, small intermediate cell in diestrus, and small intermediate cell in anestrus, respectively. There were no statistically significant differences of appearance rate of vaginal cytology among small pet bitches in the each phase of estrous cycle. These results indicated that the vaginal cytology was useful method for estimating estrous cycle and optimal breeding time in small pet bitches.

• Journal of Korea Society of Industrial Information Systems
• /
• v.7 no.5
• /
• pp.67-72
• /
• 2002

The number of keystream cycle sequences has been proposed as a characteristic of binary sequence generators for cryptographic applications, but in general most binary sequence generators have the only one-cycle sequence. In this paper, we propose a switching-tap LFSR as a basic function of a multiple-cycle binary sequence generator and the improved Rueppel's multiple-cycle generator. Finally we analyze its period, linear complexity, and the number of its keystream cycle sequences.

• The Transactions of The Korean Institute of Electrical Engineers
• /
• v.58 no.4
• /
• pp.694-699
• /
• 2009

Combined cycle plants which feature distinct advantages for power generation such as fast response, high efficiency, environmental friendliness, fuel flexiblity represent the majority of new generating plant installations across the globe. Combined cycle plants have different operating modes where the operating parameters can differ greatly depending which mode is operating at the time. This paper addresses the bidding strategy model of combined cycle plants in a competitive electricity market by using a characteristic of multiple operating modes of combined cycle plants. Simulation results of case studies show that an operating mode among multiple ones is selected strategically in generation bidding for more profit of generation company.

• Journal of Applied Reliability
• /
• v.17 no.4
• /
• pp.316-324
• /
• 2017

Purpose: The purpose of this study is to determine the replacement cycle applied age replacement policy by reliability analysis based on railway vehicle contactor's failure history data. Method: We performed reliability analysis based on railway vehicle contactor's failure history data. We found a suitable distribution by goodness of fit test and predicted the reliability through estimation of scale & shape parameter. Considering cost information we determined the replacement cycle that minimize the opportunity cost. Result: Suitable distribution was the Weibull and scale parameter & shape parameter are estimated by reliability analysis. The replacement cycle was predicted and MTTF, $B_6$ percentile life were suggested additionally. Conclusion: We confirmed that failure rate type of railway vehicle contactor is degradation model having a time dependent characteristic and examined the replacement cycle in our country's operating environment. We expect that this study result contribute to railway operation agency for maintenance policy decision.

• 한국가스학회:학술대회논문집
• /
• 1998.09a
• /
• pp.255-260
• /
• 1998

This study describes the results of Coefficient Of Performance(COP) analysis by cycle simulation for two types of absorption-compression hybride cycle using the water/Lithium Bromide solution pair, These types are basic hybride systems introducing a mechanical compression process into the refrigerant vapor phase of the single effect absorption cycle. In absorption-compression hybrid cycles, coefficient of performance is improved compared with absorption cycle. Hybride cycle Type ll is considered as a key technology to support energy utilization system, given its capability of utilizing waste heat to drive system with a high level of efficiency.

• Proceedings of the Korean Radioactive Waste Society Conference
• /
• 2009.11a
• /
• pp.53-54
• /
• 2009

The preliminary quantitative analysis of proliferation resistance for the five nuclear fuel cycles demonstrated that the thermal MOX fuel cycle is most vulnerable to proliferation due to the presence of pure $PuO_2$ in the fuel cycle, while the once-through fuel cycle has the highest proliferation resistance. The innovative next generation fuel cycles such as Pyro-SFR and Wet-SFR were found to have similar levels of proliferation resistance to that of the DUPIC fuel cycle which is believed to have proliferation resistance strong enough for commercial deployment. The sensitivity analysis also demonstrated the effectiveness of the proposed methodology in applying to existing and/or newly developing nuclear fuel cycles so as to improve the proliferation resistance characteristic of the fuel cycle systems.