• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.3
• /
• pp.1129-1133
• /
• 2015

Background: The tissue microarray (TMA) is widely accepted as a fast and cost-effective research tool for in situ tissue analysis in modern pathology. However, the current automated and manual TMA techniques have some drawbacks restricting their productivity. Our study aimed to introduce an improved manual tissue miniarray (TmA) technique that is simple and readily applicable to a broad range of tissue samples. Materials and Methods: In this study, a conventional TV/radio telescopic antenna was used to punch tissue cores manually from donor paraffin embedded tissue blocks which were pre-incubated at $40^{\circ}C$. The cores were manually transferred, organized and attached to a standard block mould, and filled with liquid paraffin to construct TmA blocks without any use of recipient paraffin blocks. Results: By using a conventional TV/radio antenna, it was possible to construct TmA paraffin blocks with variable formats of array size and number ($2-mm{\times}42$, $2.5-mm{\times}30$, $3-mm{\times}24$, $4-mm{\times}20$ and $5-mm{\times}12$ cores). Up to $2-mm{\times}84$ cores could be mounted and stained on a standard microscopic slide by cutting two sections from two different blocks and mounting them beside each other. The technique was simple and caused minimal damage to the donor blocks. H&E and immunostained slides showed well-defined tissue morphology and array configuration. Conclusions: This technique is easy to reproduce, quick, inexpensive and creates uniform blocks with abundant tissues without specialized equipment. It was found to improve the stability of the cores within the paraffin block and facilitated no losses during cutting and immunostaining.

• Polymer(Korea)
• /
• v.25 no.1
• /
• pp.63-70
• /
• 2001

The objective of this study was to investigate the effect of cure type on the processing and physical properties under conditions of similar stress-strain properties. On the carbon black filled natural rubber(NR) based compound, the induction time decreased, but the cure rate became fast with increasing loading of sulfur donor agent. Tensile strength was little affected on the curing type. However, elongation generally decreased with increasing accelerator. Effect of cure type on the blow-out properties was followings: CV

• Journal of the Korean Society for Precision Engineering
• /
• v.33 no.12
• /
• pp.971-977
• /
• 2016

Recently, the problem of the accumulation of fine sludge from the cutting oil generated during machining processes has become a major threat to the environment. The fine sludge has adverse affects on the human body and the environment, and significantly contributes to marine pollution. However, a microfiltration technique that can process the sludge still needs to be studied and developed on a global scale. Therefore, it is necessary to develop eco-friendly equipment such as an ECO vacuum filter system and eco-friendly technologies for processing cutting oil. In this study, a structural analysis was carried out using a finite element method (FEM). Improved models of the suction chamber for the ECO vacuum filter system were proposed based on the analysis of the displacement and stress of the system. The model with the best result was then optimized using the commercial software, ANSYS. It was confirmed that, in the optimized model, displacement and stress were reduced in comparison with the initial model. Finally, the structural stability of the optimized model was verified through analysis.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.40 no.7
• /
• pp.981-985
• /
• 2011

The effects of germinated brown rice flour on the quality characteristics of white wheat flour noodles were investigated. The insoluble dietary fiber and soluble dietary fiber content of germinated brown rice flour were 5.1% and 4.2%, respectively. Water absorption, development time, and stability of farinogram decreased when germinated brown rice flour was added to white wheat flour. Brightness ($L^*$) decreased, but redness ($a^*$) increased in noodles made from germinated brown rice. Volume of cooked noodles did not change upon addition of germinated brown rice flour, but weight of cooked noodles decreased and the turbidity of cooked water increased. The cutting force of cooked noodles did not change upon addition of germinated rice flour. Addition of 10% germinated brown rice flour to white wheat flour did not have any effects on flavor, color, taste, appearance, and overall acceptability in sensory evaluation.

• International Journal of Highway Engineering
• /
• v.10 no.3
• /
• pp.109-118
• /
• 2008

This study analyzes the change of stability of embankment due to the construction of embankment combined used road with two different construction phases. The stabilities have been checked both in the phase of earth banking for a road construction and in the phase of the application of the traffic roads(DB-24). In both cases the factor of safety has been found higher than 1.3 which is the general criterion of the safety of an embankment. The results indicate that the safety of an embankment due to the construction of embankment combined use road is assured, and thus, it is thought that the construction of embankment combined use road can be considered for cutting down on expenses of construction sites for a road construction. However, the pre-examination of stability due to the construction should be carried out because it decreases the factor of safety of an embankment. From this study, it has been found that the factor of safety was dropped most when the water level rose in the transient flow. The result indicates that the stability analysis of a river embankment where the water level changes frequently should be carried out in the condition of transient flow. It is recommended that the inner side of an embankment should have a slope of 1:2 which is identical with the slope of the existing embankment. In addition, the factor of safety also can be decreased due to the traffic loads, and therefore, the effect should also be considered after the construction of embankment combined used road limiting the traffic loads.

• Geomechanics and Engineering
• /
• v.15 no.5
• /
• pp.1113-1124
• /
• 2018

Geological dynamic hazards during deep coal mining are caused by the failure of a composite system consisting of the rock and coal layers, whereas the joint in coal affects the stability of the composite system. In this paper, the compression test simulations for the rock-coal combined body with single joint in coal were conducted using $PFC^{2D}$ software and especially the effects of joint length and joint angle on strength and failure characteristics in a rock-coal combined body were analyzed. The joint length and joint angle exhibit a deterioration effect on the strength and affect the failure modes. The deterioration effect of joint length of L on the strength can be neglected with a tiny variation at ${\alpha}$ of $0^{\circ}$ or $90^{\circ}$ between the loading direction and joint direction. While, the deterioration effect of L on strength are relatively large at ${\alpha}$ between $30^{\circ}$ and $60^{\circ}$. And the peak stress and peak strain decrease with the increase of L. Additionally, the deterioration effect of ${\alpha}$ on the strength becomes larger with the increase of L. With the increase of ${\alpha}$, the peak stress and peak strain first decrease and then increase, presenting "V-shaped" curves. And the peak stress and peak strain at ${\alpha}$ of $45^{\circ}$ are the smallest. Moreover, the failure mainly occurs within the coal and no apparent failure is observed for rock. At ${\alpha}$ between $30^{\circ}$ and $60^{\circ}$, the secondary shear cracks generated in or close to the joint tips, cause the structural instability failure of the combined body. Therefore, their failure models present as a shear failure along partial joint plane direction and partially cutting across the coal body or a shear failure along the joint plane direction. However, at ${\alpha}$ of $60^{\circ}$ and L of 10 mm, the "V-shaped" shear cracks cutting across the coal body cause its final failure. While crack nucleations at ${\alpha}$ of $0^{\circ}$ or $90^{\circ}$ are randomly distributed in the coal, the failure mode shows a V-shaped shear failure cutting across the coal body.

• Journal of Korean Society for Geospatial Information Science
• /
• v.15 no.4
• /
• pp.59-69
• /
• 2007

The scale of a natural disaster grows bigger and bigger every year. The government spends much of its budget on recovering the resulting damage on a national scale. It is important to shift the paradigm from taking measures after a disaster to that of taking preventive actions before a disaster in order to bring a fundamental resolution to such problems. In taking preventive actions and policies, it is necessary to integrate various kinds of advanced technologies including IT, high-tech information gathering technology and operational technology, and to predict and evaluate natural disasters on a comprehensive level. Although Korea is a country with a strong IT sector, most information gathering is still performed in paper. In particular, information about the areas of previous landslide occurrences and slopes remains on paper, which makes it difficult to share the information and to discern the contents, and also raises the possibility of missing documents. Thus this study set out to develop an information gathering and management system for cutting slopes using PDA from the perspective of information gathering, system compatibility, and information management. As a result, field information may be gathered in a variety of forms (location, photos, and texts) real-time. A rough judgment was also made of the stability of rock slopes using the SMR method on the field.

• Journal of Biosystems Engineering
• /
• v.41 no.4
• /
• pp.288-293
• /
• 2016

Purpose: The purpose of this study was to investigate the key factors in designing a three-wheeled two-row soybean reaper (riding type) that is suitable for soybean production, and ensure worker safety by proposing optimal work conditions for the prototype of the designed machine in relation to the slope of the road. Methods: A three-wheeled two-row soybean reaper (riding type) was designed and its prototype was fabricated based on the local soybean-production approach. This approach was considered to be closely related to the prototype-designing of the cutter and the wheel driving system of the reaper. Load distribution on the wheels of the prototype, its minimum turning radius, static lateral overturning angle, tilt angle during driving, and The working and rear overturning (back flip) angle were measured. Based on the gathered information, investigations were conducted regarding optimal work conditions for the prototype. The investigations took into account driving stability and worker safety. Results: The minimum ground clearance of the prototype was 0.5 m. The blade height of the prototype was adjusted such that the cutter was operated in line with the height of the ridges. The load distribution on the prototype's wheels was found to be 1 (front wheel: F): 1.35 (rear-left wheel: RL): 1.43 (rear-right wheel: RR). With the ratio of load distribution between the RL and RR wheels being 1: 1.05, the left-to-right lateral loads were found to be well-balanced. The minimum turning radius of the prototype was 2.0 m. Such a small turning radius was considered to be beneficial for cutting work on small-scale fields. The sliding of the prototype started at $25^{\circ}$, and its lateral overturning started at $39.3^{\circ}$. Further, the critical slope angle for the worker to drive the prototype in the direction of the contour line on an incline was found to be $12.8^{\circ}$, and the safe angle of slope for the cutting was measured to be less than $6^{\circ}$. The critical angle of slope that allowed for work was found to be $10^{\circ}$, at which point the prototype would overturn backward when given impact forces of 1,060 N on its front wheel. Conclusions: It was determined that farmers using the prototype would be able to work safely in most soybean production areas, provided that they complied with safe working conditions during driving and cutting.

• Proceedings of the Korean Geotechical Society Conference
• /
• 2003.06a
• /
• pp.65-81
• /
• 2003

During the last few decades in Korea, the development of hillside or mountain areas has rapidly increased for infrastructure construction such as railroads, highways and housing. Many landslides have occurred during these constructions. Also, the amount and scale of damage caused by landslides have increased every year. In the case of Far East Asia including Korea, the damage of landslides is consequently reported during the wet season. In this paper, the effect of stabilizing piles on slope stability is checked and the behavior of slope soil and piles are observed throughout the year by field measurements in the large-scale cut slopes. In particular a large-scale cut slope situated on the construction site for the express highway in Donghae, Korea. First of all, The behavior of the slope soil was measured by inclinometers during slope modification. Landslides occurred in this area due to the soil cutting for slope modification. The horizontal deformations of slope soil gradually increased and rapidly decreased at depth of sliding surface indicating that the depth of sliding surface below the ground surface can be predicted. On the basis of being able to predict the depth of the sliding surface, stabilizing piles were designed and constructed in this slope. To ensure the stability of the reinforced slope using stabilizing piles, an instrumentation system was installed. The maximum deflection of piles is measured at the pile head and it is noted that the piles deform like deflection on a cantilever beam. The maximum bending stress of piles is measured at the soil layer. The pile above the soil layer is subjected to lateral earth pressure due to driving force of the slope, while pile below soil layer is subjected to subgrade reaction against pile deflection. As a result of research, the effect and applicability of stabilizing piles in large-scale cut slopes could be confirmed sufficiently.

• Proceedings of the KSR Conference
• /
• 2011.10a
• /
• pp.2090-2100
• /
• 2011

Railway rail fastening system is the critical device which gives big influences to not only the vehicle driving stability and the orbit's structural stability against the impulsive load, but also the noise vibration and the ride comfort. As a part of the low-carbon green growth, the importance of the railroad industry is getting highlights on its excellent energy-efficiency and eco-friendliness. However, so far the Korea's domestic rail fastening system technology is not so good and the technical reliance to abroad is very heavy. In this study, we conducted comparative analysis on the rail fastening system with new and used one of the same type. And those systems are imported by Seoul Metro and are being used by it. With this basis, we developed the components and the materials and then, established the durability assessment methods appropriate to the Korean domestic circumstances. And through the reliability qualification test on the 7 parts of the rail fastening system, we've improved the reliability and guaranteed the 15 years of service lifetime. ($B_{10}Life15$) Establishment and standardization of Reliability Standard on the parts of the rail fastening system such as anti-vibration pads, guide-plate, screw spike made it possible to perform the internationally fair assessment. And it is thought that we can satisfy the manufactures' and consumers' needs of cost-cutting and qualification security by shortening of assessment period on rail fastening system.