• Journal of Pharmaceutical Investigation
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• v.37 no.3
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• pp.137-148
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• 2007

Using a strain-controlled rheometer [Rheometrics Dynamic Analyzer (RDA II)], the steady shear flow properties of a semi-solid ointment base (vaseline) have been measured over a wide range of shear rates at temperature range of $25{\sim}60^{\circ}C$. In this article, the steady shear flow properties (shear stress, steady shear viscosity and yield stress) were reported from the experimentally obtained data and the effects of shear rate as well as temperature on these properties were discussed in detail. In addition, several inelastic-viscoplastic flow models including a yield stress parameter were employed to make a quantitative evaluation of the steady shear flow behavior, and then the applicability of these models was examined by calculating the various material parameters (yield stress, consistency index and flow behavior index). Main findings obtained from this study can be summarized as follows : (1) At temperature range lower than $40^{\circ}C$, vaseline is regarded as a viscoplastic material having a finite magnitude of yield stress and its flow behavior beyond a yield stress shows a shear-thinning (or pseudo-plastic) feature, indicating a decrease in steady shear viscosity as an increase in shear rate. At this temperature range, the flow curve of vaseline has two inflection points and the first inflection point occurring at relatively lower shear rate corresponds to a static yield stress. The static yield stress of vaseline is decreased with increasing temperature and takes place at a lower shear rate, due to a progressive breakdown of three dimensional network structure. (2) At temperature range higher than $45^{\circ}C$, vaseline becomes a viscous liquid with no yield stress and its flow character exhibits a Newtonian behavior, demonstrating a constant steady shear viscosity regardless of an increase in shear rate. With increasing temperature, vaseline begins to show a Newtonian behavior at a lower shear rate range, indicating that the microcrystalline structure is completely destroyed due to a synergic effect of high temperature and shear deformation. (3) Over a whole range of temperatures tested, the Herschel-Bulkley, Mizrahi-Berk, and Heinz-Casson models are all applicable and have an almostly equivalent ability to quantitatively describe the steady shear flow behavior of vaseline, whereas the Bingham, Casson,and Vocadlo models do not give a good ability.

• Journal of Astronomy and Space Sciences
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• v.33 no.2
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• pp.127-135
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• 2016

Inactive space objects are usually rotating and tumbling as a result of internal or external forces. KOREASAT 1 has been inactive since 2005, and its drift trajectory has been monitored with the optical wide-field patrol network (OWL-Net). However, a quantitative analysis of KOREASAT 1 in regard to the attitude evolution has never been performed. Here, two optical tracking systems were used to acquire raw measurements to analyze the rotation period of two inactive satellites. During the optical campaign in 2013, KOREASAT 1 was observed by a 0.6 m class optical telescope operated by the Korea Astronomy and Space Science Institute (KASI). The rotation period of KOREASAT 1 was analyzed with the light curves from the photometry results. The rotation periods of the low Earth orbit (LEO) satellite ASTRO-H after break-up were detected by OWL-Net on April 7, 2016. We analyzed the magnitude variation of each satellite by differential photometry and made comparisons with the star catalog. The illumination effect caused by the phase angle between the Sun and the target satellite was corrected with the system tool kit (STK) and two line element (TLE) technique. Finally, we determined the rotation period of two inactive satellites on LEO and geostationary Earth orbit (GEO) with light curves from the photometry. The main rotation periods were determined to be 5.2 sec for ASTRO-H and 74 sec for KOREASAT 1.

• Nutrition Research and Practice
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• v.8 no.4
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• pp.368-376
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• 2014

BACKGROUND/OBJECTIVES: The objectives of this study were to investigate the effects of lycopene on the migration, adhesion, tube formation capacity, and p38 mitogen-activated protein kinase (p38 MAPK) activity of endothelial progenitor cells (EPCs) cultivated with high glucose (HG) and as well as explore the mechanism behind the protective effects of lycopene on peripheral blood EPCs. MATERIALS/METHODS: Mononuclear cells were isolated from human peripheral blood by Ficoll density gradient centrifugation. EPCs were identified after induction of cellular differentiation. Third generation EPCs were incubated with HG (33 mmol/L) or 10, 30, and $50{\mu}g/mL$ of lycopene plus HG. MTT assay and flow cytometry were performed to assess proliferation and apoptosis of EPCs. EPC migration was assessed by MTT assay with a modified boyden chamber. Adhesion assay was performed by replating EPCs on fibronectin-coated dishes, after which adherent cells were counted. In vitro vasculogenesis activity was assayed by Madrigal network formation assay. Western blotting was performed to analyze protein expression of both phosphorylated and non-phosphorylated p38 MAPK. RESULTS: The proliferation, migration, adhesion, and in vitro vasculogenesis capacity of EPCs treated with 10, 30, and $50{\mu}g/mL$ of lycopene plus HG were all significantly higher comapred to the HG group (P < 0.05). Rates of apoptosis were also significantly lower than that of the HG group. Moreover, lycopene blocked phosphorylation of p38 MAPK in EPCs (P < 0.05). To confirm the causal relationship between MAPK inhibition and the protective effects of lycopene against HG-induced cellular injury, we treated cells with SB203580, a phosphorylation inhibitor. The inhibitor significantly inhibited HG-induced EPC injury. CONCLUSIONS: Lycopene promotes proliferation, migration, adhesion, and in vitro vasculogenesis capacity as well as reduces apoptosis of EPCs. Further, the underlying molecular mechanism of the protective effects of lycopene against HG-induced EPC injury may involve the p38 MAPK signal transduction pathway. Specifically, lycopene was shown to inhibit HG-induced EPC injury by inhibiting p38 MAPKs.

• IMMUNE NETWORK
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• v.6 no.1
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• pp.43-51
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• 2006

Background: The DR-$70^{TM}$ immunoassay is a newly developed cancer diagnostic test which quantifies the serum fibrin degradation products (FDP), produced during fibrinolysis, by antibody reaction. The purpose of this study was to evaluate the potential of DR-$70^{TM}$ Immunoassay in screening malignant tumor. Methods: Sample subjects were 4,169 adults, both male and female, who visited the health promotion center of a general hospital from March 2004 to April 2005 and underwent the DR-$70^{TM}$ immunoassay test and other tests for cancer diagnosis. The patient group was defined as 42 adults out of the sample subjects who were newly diagnosed with cancer during the same time period when the DR-$70^{TM}$ immunoassay test was performed. Final confirmation of a malignant tumor was made by pathological analysis. Results: The mean DR-$70^{TM}$ level was $0.83{\pm}0.65{\mu}g/ml$ (range: 0.00 (0.0001)${\sim}7.42{\mu}g/ml)$ in the control group (n=4,127) as opposed to $2.70{\pm}2.33{\mu}g/ml$ (range: $0.12{\sim}9.30{\mu}g/ml)$ in the cancer group (n=42), and statistical significance was established (p<0.0001, Student t-test). When categorized by the type of malignant tumor, all cancer patients with the exception of the subgroups of colon and rectal cancer showed significantly higher mean DR-$70^{TM}$ levels compared with the control group (p<0.0001, Kruscal-Wallis test). The receiver operating characteristic (ROC) curve analysis revealed ${\geq}1.091{\mu}g/ml$ as the best cut-off value. Using this cut-off value, the DR-$70^{TM}$ immunoassay produced a sensitivity of 71.4%, a specificity of 70.1%, a positive predictability of 69.4%, and a negative predictability of 69.2% (1). Conclusion: A significant increase in the mean DR-$70^{TM}$ value was observed in the cancer group (thyroidal, gastric, breast, hepatic and ovarian) com pared with the control group. In particular, the specificity and sensitivity of the DR-$70^{TM}$ immunoassay was relatively high in the subgroups of breast, gastric, and thyroidal cancer patients. There is need for further studies on a large number of malignant tumor patients to see how the DR-$70^{TM}$ level might be changed according to the differentiation grade and postoperative prognosis of the malignant tumor.

• Journal of the Korean Geographical Society
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• v.46 no.6
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• pp.673-692
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• 2011

Advances in computer technology have enabled us to develop and use numerical landscape evolution models (NLEMs) for exploring the dynamics of geomorphic system from a variety of viewpoints which previously could have not been taken. However, as of yet there have been no trials using or developing NLEMs in Korea. The purpose of this research is to develop a 2 dimensional NLEM on a geological time scale and evaluate its usefulness. The newly developed NLEM (ND-NLEM) treats bedrock weathering as one of the major geomorphic processes and attempts to simulate the thickness of soil. As such it is possible to model the weathering-limited as well as the transport-limited environment on hillslopes. Moreover the ND-NLEM includes not only slow and continuous mass transport like soil creep, but also rapid and discrete mass transport like landslides. Bedrock incision is simulated in the ND-NLEM where fluvial transport capacity is large enough to move all channel bed loads, such that ND-NLEM can model the detachment-limited environment. Furthermore the ND-NLEM adopts the D-infinity algorithm when routing flows in the model domain, so it reduces distortion due to the use of the steepest descent slope flow direction algorithm. In the experiments to evaluate the usefulness of the ND-NLEM, characteristics of the channel network observed from the model results were similar to those of the case study area for comparison, and the hypsometry curve log during the experiment showed rational evidence of landscape evolution. Therefore, the ND-NLEM is shown to be useful for simulating landscape evolution on a geological time scale.

• Proceedings of the Korea Inteligent Information System Society Conference
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• 2004.11a
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• pp.249-258
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• 2004

오늘날 활발하게 이루어지고 있는 유비쿼터스 컴퓨팅 관련 기술 연구는 사용자가 시간과 장소에 구애받지 않고 네트워크에 접근해 다양한 컴퓨터 관련 서비스를 제공 받을 수 있는 방법에 초점을 맞추고 있다. 이 처럼 시간과 공간의 한계를 뛰어 넘은 네트워크로의 자유로운 접근은 일상 생활의 패러다임을 바꾸어 놓게 될 것이다. 유비쿼터스 컴퓨팅 기술을 통해 가장 큰 변화가 일어나는 분야는 일반 가정환경에서 일어나는 인텔리전트 홈 네트워크 (Intelligent Home Network) 라고 할 수 있다. 집에 들어오면, 자동으로 문을 열어주고, 불을 켜주며, 놓쳤던 TV 프로그램을 자동으로 녹화해 놓았다가 원하는 시간에 보여주고, 적당한 시간에 목욕물을 미리 받아준다. 또한 집밖으로 나가기 전, 일기예보에 따라 우산을 챙겨주고, 일정을 확인시켜주며 입고 나갈 옷을 골라줄 수도 있다. 이 모든 일들이 유비쿼터스 컴퓨팅 기술이 가져올 인텔리전트 홈 네트워크의 모습이다. 그러나, 모든 사용자에게 효과적인 서비스를 제공하기 위해서는 홈 네트워크 상의 자원 관리에서 일어날 수 있는 에이전트들간의 자원 접근 권한 충돌을 효율적으로 방지할 수 있는 기술이 필요하다. 유비쿼터스 컴퓨팅 환경에서 자원관리 특성은 점유의 연속성, 자원 사이의 연관성, 그리고 자원과 사용자 사 사이의 연계성의 3 가지 특성을 지니고 있다. 본 논문에서는 유비쿼터스 컴퓨팅 환경에서 일어날 수 있는 자원 충돌 상황을 효율적으로 처리하기 위한 자원 협상 방법을 제안한다. 본 방법은 자원 관리 특성을 바탕으로 시간논리에 기반을 둔 자원 선점과 분배 규칙으로 구성된다.트 시스템은 b-Cart를 기반으로 할 것으로 예측할 수 있다.타났다. 또한, 스네이크의 초기 제어점을 얼굴은 44개, 눈은 16개, 입은 24개로 지정하여 MER추출에 성공한 영상에 대해 스네이크 알고리즘을 수행한 결과, 추출된 영역의 오차율은 각각 2.2%, 2.6%, 2.5%로 나타났다.해서 Template-based reasoning 예를 보인다 본 방법론은 검색노력을 줄이고, 검색에 있어 Feasibility와 Admissibility를 보장한다.매김할 수 있는 중요한 계기가 될 것이다.재무/비재무적 지표를 고려한 인공신경망기법의 예측적중률이 높은 것으로 나타났다. 즉, 로지스틱회귀 분석의 재무적 지표모형은 훈련, 시험용이 84.45%, 85.10%인 반면, 재무/비재무적 지표모형은 84.45%, 85.08%로서 거의 동일한 예측적중률을 가졌으나 인공신경망기법 분석에서는 재무적 지표모형이 92.23%, 85.10%인 반면, 재무/비재무적 지표모형에서는 91.12%, 88.06%로서 향상된 예측적중률을 나타내었다.ting LMS according to increasing the step-size parameter $\mu$ in the experimentally computed. learning curve. Also we find that convergence speed of proposed algorithm is increased by (B+1) time proportional to B which B is the number of recycled data b

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.9 no.4
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• pp.17-24
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• 2009

This paper deals with the cancellation performance of loop back interference signal in the case of multihop relay of 16-QAM received signal at the USN radio network. For this, it is necessary to the exchange of information with long distance located station by means of the relay function between the node in the USN environment. In the relay node, the loop-back interference signal which the retransmitting signal is feedback to the receiver side due to the antenna of transmitter and receiver are co-used or very colsely located or using the nonlinear device. Due to this signal, the performance of USN system are degraded which are using the limited resource of frequency and power. For improve this, it is necessary to applying the adaptive signal processing algorithm in order to cancellating the unwanted loop-back interference signal at the frontend of receiver in relaying node, we can get the better system and multi hop performance. In the adaptive signal processing, we considered the 16-QAM signal which has a good spectral efficiency, firstly, than, the QR-Array RLS algorithm was used that has a fairly good convergence property and the solving the finite length problem in the H/W implementation. Finaly, we confirmed that the good elimination performanc was confirmed by computer simulation in the learing cuved and received signal constellation compared to the conventional RLS.

• Journal of Wetlands Research
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• v.17 no.4
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• pp.348-358
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• 2015

Impacts of climate change are being observed in the globe as well as the Korean peninsula. In the past 100 years, the average temperature of the earth rose about 0.75 degree in celsius, while that of Korean peninsula rose about 1.5 degree in celsius. The fifth Assessment Report of IPCC(Intergovermental Panel on Climate Change) predicts that the water pollution will be aggravated by change of hydrologic extremes such as floods and droughts and increase of water temperature (KMA and MOLIT, 2009). In this study, future runoff was calculated by applying climate change scenario to analyze the future water quality for each targe period (Obs : 2001 ~ 2010, Target I : 2011 ~ 2040, Target II : 2041 ~ 2070, Target III : 2071 ~ 2100) in Hongcheon river basin, Korea. In addition, The future water quality was analyzed by using multiple linear regression analysis and artificial neural networks after flow-duration curve analysis. As the results of future water quality prediction in Hongcheon river basin, we have known that BOD, COD and SS will be increased at the end of 21 century. Therefore, we need consider long-term water and water quality management planning and monitoring for the improvement of water quality in the future. For the prediction of more reliable future water quality, we may need consider various social factors with climate components.

• Journal of the HCI Society of Korea
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• v.5 no.1
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• pp.37-43
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• 2010

Twitter has been continuously growing since October, 2006. Especially, not only the users and the number of messages have been increasing but also a new concept in social networking called 'micro blogging' has diffused. Within Korea, service such as 'me2day' has already been introduced and the improvement of internet accessibility within mobile devices is expected to expand the 'micro blogs'. In this point, this research is executed to study the new medium, 'micro blog'. To do so, we collected and analyzed Twitter logs of Korean users. Especially, we were curious about the extreme heavy users using Twitter, despite of the linguistic and cultural barrier of the foreign service. Who they are, why and how they use the 'micro blog'. First, we reviewed the general aspect of followers and messages by collecting a certain number of random samples. Using the Lorenz curve we found out that there was the imbalance within the users and based on this phenomenon we deducted an extreme heavy user group. In order to perform further analysis, log analysis was performed on the extreme heavy users. As the result, the users used multiple mobile and desktop 'Twitter' clients. The usage pattern was similar to that of internet usage time but was used during their "micro" time. The users using 'Twitter' not only to spread messages about important information, special events and emotions, but also as a habitual 'chatting tool' to express ordinary personal chats similar to SMS and IM services. In this research, it is proved that 68% of the total messages were ordinary personal chats. Also, with 24% of the total messages were retweets, we were able to find out that virtually connected 'people' and 'relationships' acted as the dominant trigger of their articulation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.8 no.4
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• pp.748-757
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• 2007

This paper is intended to solve the technical problem that fails in large-capacity induction motor starting due to serious voltage drop during starting period. One induction motor that is established already can reach in steady-state using reactor starting method but the voltage magnitude of PCC (point of common coupling) has dropped down a little. When the same capacity induction motor is installed additionally in the PCC, where the existing induction motor is operating, voltage drop becomes more serious by starting of additional induction motor. As a result, the additional induction motor fails in starting. Therefore, voltage compensation method is proposed so that all of two induction motors can be started completely. First, modeling technique is described in order to implement starting characteristics of large induction motor. And then, this paper proposes strategic starting scheme by proper voltage compensation that use no-load transformer tap control (NLTC) and step voltage regulator (SVR) for starting of two large induction motors successfully and improving the feeding network voltage profile during the starting period. The induction motor discussed in this paper is the pumped induction motor of 2500kVA capacity that is operating by KOWACO (Korea Water Resources Corporation). Modeling and simulation is conducted using PSCAD/EMTDC software.