• The Korean Journal of Physiology and Pharmacology
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• v.24 no.1
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• pp.101-110
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• 2020

Transient receptor potential canonical 4 (TRPC4) channel is a nonselective calcium-permeable cation channels. In intestinal smooth muscle cells, TRPC4 currents contribute more than 80% to muscarinic cationic current (mIcat). With its inward-rectifying current-voltage relationship and high calcium permeability, TRPC4 channels permit calcium influx once the channel is opened by muscarinic receptor stimulation. Polyamines are known to inhibit nonselective cation channels that mediate the generation of mIcat. Moreover, it is reported that TRPC4 channels are blocked by the intracellular spermine through electrostatic interaction with glutamate residues (E728, E729). Here, we investigated the correlation between the magnitude of channel inactivation by spermine and the magnitude of channel conductance. We also found additional spermine binding sites in TRPC4. We evaluated channel activity with electrophysiological recordings and revalidated structural significance based on Cryo-EM structure, which was resolved recently. We found that there is no correlation between magnitude of inhibitory action of spermine and magnitude of maximum current of the channel. In intracellular region, TRPC4 attracts spermine at channel periphery by reducing access resistance, and acidic residues contribute to blocking action of intracellular spermine; channel periphery, E649; cytosolic space, D629, D649, and E687.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.25 no.2
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• pp.199-207
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• 2014

Although High-altitude electromagnetic pulse(HEMP) protection filter meets the requirements of pulsed current injection(PCI) acceptance test, the equipment under test which has low electromagnetic susceptibility level can be damaged during PCI verification test that is performed on operating condition of equipment. This paper proposed the HEMP effect analysis method using comparison of norms between residual current of HEMP filter and transient electromagnetic conducted susceptibility criteria of equipment, as an alternative method under the condition that performing PCI verification test is limited in HEMP hardened facilities. PCI acceptance test of HEMP filter, transient electromagnetic conducted susceptibility test, and PCI verification test are performed and test results are analyzed.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.65 no.12
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• pp.2000-2007
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• 2016

Generally, in order to implement the CRM(Critical Conduction Mode), the analog controller is used rather than a digital controller because the control is simple and uses less power. However, according to the semiconductor technology development and various user needs, digital control system based on a DSP is on the rise. Therefore, in this paper, the CRM bridgeless PFC converter based on a digital control is proposed. It is necessary to detect the inductor current when it reaches zero and peak value, for calculating the on time and off time by using the current information. However, in this paper, the on-time and off-time are calculated by using the proposed algorithm without any current information. If the switching-times are calculated through the steady-state analysis of the converter, they do not reflect transient status such as starting-up. Therefore, the calculated frequency is out of range, and the transient current is generated. In order to solve these problems, limitation method of the on-time and off-time is used, and the limitation values are varied according to the voltage reference. In addition, in steady state, depending on the switching frequency, the inductance is varied because of the resonance between the inductor and the parasitic capacitance of the switching elements. In order to solve the problem, inductance are measured depending on the switching frequency. The measured inductance are used to calculate the switching time for preventing the transient current. Simulation and experimental results are presented to verify the proposed method.

• Progress in Superconductivity and Cryogenics
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• v.4 no.1
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• pp.66-72
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• 2002

This paper describes numerical modeling for thermal characteristic of vapor-cooled current leads under pulse operation. The transient thermal analysis considers the temperature difference between a helium gas (low and a copper lead and temperature dependent properties of helium gas, copper and stainless steel. This numerical modeling was compensated and validated by an experiment with commercially available 100 A vapor-cooled current leads. A proper overloading factor was suggested for the current leads under pulse operation through this modeling, which can significantly reduce heat input to a cryostat.

• 전기의세계
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• v.28 no.12
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• pp.41-45
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• 1979

Improvement of power factor is achieved by reactive-current compensation, connecting power condenser to the circuit. This paper describes a method of reactive-current compensation, employing thyristor switching of capacitor banks without any breaker. This method reduces supply transients to the minimum by means of connecting condenser, because thyristor is triggered at zero point in condenser current. The reactive current detection and the experimental system to trigger thyristor at appropriate moment are given. IThe results show the fast reactive-current compensation on the condition of minimum transient.

• Journal of Electrical Engineering and Technology
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• v.8 no.5
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• pp.1182-1187
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• 2013

Transient radiation is emitted during a nuclear explosion and causes fatal errors as upset and latch-up in CMOS circuits. This paper proposes the transient radiation SPICE models of NMOS, PMOS, and INVERTER based on the transient radiation analysis using TCAD (Technology Computer Aided Design). To make the SPICE model of a CMOS circuit, the photocurrent in the PN junction of NMOS and PMOS was replaced as current source, and a latch-up phenomenon in the inverter was applied using a parasitic thyristor. As an example, the proposed transient radiation SPICE model was applied to a CMOS NAND circuit. The CMOS NAND circuit was simulated by SPICE and TCAD using the 0.18um CMOS process model parameter. The simulated results show that the SPICE results were similar to the TCAD simulation and the test results of commercial CMOS NAND IC. The simulation time was reduced by 120 times compared to the TCAD simulation.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.20 no.1
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• pp.65-70
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• 2006

This paper presents the transient behaviors of grounding system impedance against lightning impulse currents. The dynamic characteristics of the deeply driven ground rod and grounding grid subjected to the impulse current were investigated. The transient ground impedance strongly depends on the configuration and size of grounding electrodes and the shapes of impulse currents, and the inductance of grounding electrodes has a significant affect on the transient ground impedance of grounding system Also, the deeply-driven ground rod was effective to reduce the transient ground impedance in time domain of miceroseconds.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1993.10a
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• pp.482-487
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• 1993

A prediction method for determining the welding residual stress by artificial neural network is proposed. A three-dimensional transient thermomechanical analysis has been performed for the CO $_{2}$ Arc Welding using the finite element method. The validity of the above results is demonstrated by experimental elastic stress relief method which is called Holl Drilling Method. The first part of numarical analysis performs a three-dimensional transient heat transfer anslysis, and the second part then uses results of the first part and performs a three-dimensional transient thermo-clasto-plastic analysis to compute transient and residual stresses in the weld. Data from the finite element method were used to train a backpropagation neural network to predict residual stress. Architecturally, the finite element method were used to train a backpropagation voltage and the current, a hidden layer to accommodate failure mechanism mapping, and an output layer for residual stress. The trained network was then applied to the prediction of residual stress in the four specimens. The results of predicted residual stress have been very encouraging.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.54 no.8
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• pp.410-417
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• 2005

This paper analyses the transient phenomena against single line to ground fault and lightning surge on underground power cable systems. For analysis in various fault conditions, several actual underground power cable systems are modeled using ATP In ground fault, the transient characteristic of the conductor and the sheath according to the fault current and the installation types of CCPU are analysed. In lightning surge strokes, the various unbalanced conditions including the length of crossbonded lead, the breakdown of CCPU and distance unbalance are considered. This paper is expected to contribute the establishment of proper protection methods against transients on underground power cable systems.

• 한국신재생에너지학회:학술대회논문집
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• 2007.06a
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• pp.539-542
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• 2007

The transient response of PEMFC (proton exchange membrane fuel cell) is important criteria in the application of PEM fuel cell to real automotive system. In this work, using a transparent unit PEM fuel cell, the transient response and cathode flooding during load change are investigated. The cell voltage is acquired according to the current density change($0.3Acm^2$ to $0.6A/cm^2$) under various stoichiometry conditions and different flooding intensities, Also the cathode gas channel images are obtained by CCD imaging system simultaneously. The different level of undershoots appeared at the moment of load changes under different cathode stoichiometries and flooding intensities. The correlation of the dynamic behavior with stoichiometry and cathode flooding is induced from the results of these experiments.