• Safety and Health at Work
• /
• 제11권4호
• /
• pp.485-490
• /
• 2020

Background: Meniscal tears are among the major risk factors for knee osteoarthritis progression. This study aimed to investigate the relationship between meniscal tears and work-related factors in the farming occupation. Methods: The participants included 486 farmers (238 men and 248 women), aged 40-69 years, who were among the 550 farmers registered in the Korea Farmer's Knee Cohort (KFKC). Data such as those on gender, age, body mass index (BMI), mechanical axis, cumulative heavy-lifting working time (CLWT), cumulative squatting working time (CSWT), and previous knee injury history were collected from the questionnaire, along with whole leg radiographic findings. Two radiologists assessed the magnetic resonance images of both knees to confirm the presence of meniscal tears. The factors related to meniscal tears were analyzed by multiple logistic regression. Results: A total of 54.5% of the farmers (48.7% of men and 60.1% of women) had meniscal tears. These tears were associated with gender, age, and BMI. We also identified an association between meniscal tears and CSWT, an especially important factor in farming [10,000-19,999 working hours, odds ratio = 2.16, 95% confidence interval (CI): 1.14-4.07, ≥20,000 working hours, odds ratio = 2.35, 1.45-3.80]. However, mechanical axis, knee injury history, and CLWT were not significantly related to meniscal tears. Conclusion: This study's findings show that squatting for long periods, as an occupational factor, is related to meniscal tears.

• Tuberculosis and Respiratory Diseases
• /
• 제82권4호
• /
• pp.341-347
• /
• 2019

Background: Information about the epidemiology of venous thromboembolism (VTE) recurrence in Korea is lacking. The purpose of this study was to investigate VTE cumulative recurrence rates and identify risk factors for VTE recurrence among Korean adults. Methods: A retrospective cohort study was conducted on adult patients (${\geq}18years$) admitted to a university teaching hospital for pulmonary embolism (PE) from 2005 to 2013. The main outcome of interest was a recurrence of VTE. We used Cox proportional hazard regression analyses to calculate the relative risk of VTE recurrence. Results: Five-year cumulative incidence of recurrent VTE events was 21.5% (95% confidence interval [CI], 17.7-25.4) in all cases of PE; 17% after provoked and 27% after unprovoked PE. Multivariate analysis showed that body mass index (BMI) of ${\geq}25$ (hazard ratio [HR], 2.02; 95% CI, 1.17-3.46; p=0.01) and longer anticoagulation therapy duration (HR, 0.90; 95% CI, 0.84-0.96; p<0.01) were independently associated with risk of VTE recurrence. Risk factors not found to be statistically significant at the <0.05 level included history of VTE (HR, 1.81; 95% CI, 0.84-3.88; p=0.12), unprovoked PE (HR, 1.70; 95% CI, 0.89-3.25; p=0.10), symptomatic deep vein thrombosis (HR, 1.62; 95% CI, 0.89-2.94; p=0.10), and female sex (HR, 1.42; 95% CI, 0.78-2.55; p=0.24). We found that age, history of cancer, and other co-morbidities did not significantly affect the risk of VTE recurrence. Conclusion: Recurrence of VTE after PE is high. Patients with BMI ${\geq}25$ or reduced anticoagulation therapy duration have a higher risk of recurrent VTE.

• 한국구조물진단유지관리공학회 논문집
• /
• 제27권6호
• /
• pp.39-46
• /
• 2023

이 연구에서는 차세대 고속철의 증가하는 주행속도에 따라 600 km/h 까지 10 km/h 간격으로 고속철 PSC 박스 연속교량의 교량받 침에 대한 동적거동을 수치해석하였다. 경부 고속철 구간의 40미터 단경간과 2경간 연속 PSC 박스교를 연구대상으로 프레임모형을 구성하였 으며, 38자유도의 관성질량 차량모형 및 교량과 궤도의 불규칙성을 포함한 상호작용력을 고려하였다. 주행속도별 교량받침의 종방향 변위와 누적이동거리와 변위속도를 산정하여 교량의 동적거동 추이분석과 비교하였다. 또한 마찰판의 내구성능평가를 위한 장기마찰시험 기준을 적 용하였다.

• 한국축산식품학회지
• /
• 제36권6호
• /
• pp.719-728
• /
• 2016

The aim of this study was to explore the volatile compounds of hind leg, foreleg, abdomen and Longissimus dorsi in both male and female Hyla rabbit meat by solid phase microextraction tandem with gas chromatography mass spectrometry, and to seek out the key odorants via calculating the odor activity value and principal component analysis. Cluster analysis is used to study the flavor pattern differences in four edible parts. Sixty three volatile compounds were detected, including 23 aldehydes, 4 alcohols, 5 ketones, 11 esters, 5 aromatics, 8 acids and 7 hydrocarbons. Among them, 6 aldehydes and 3 acids were identified as the potential key odorants according to the ratio of concentration and threshold. The contents of volatile compounds in male Hyla rabbit meat were significantly higher than those in female one (p<0.05). The results of principal component analysis showed that the first two principal component cumulative variance contributions reach 87.69%; Hexanal, octanal, 2-nonenal, 2-decenal and decanal were regard as the key odorants of Hyla rabbit meat by combining odor activity value and principal component analysis. Therefore volatile compounds of rabbit meat can be effectively characterized. Cluster analysis indicated that volatile chemical compounds of Longissimus dorsi were significantly different from other three parts, which provide reliable information for rabbit processing industry and for possible future sale.

• Journal of Pharmaceutical Investigation
• /
• 제36권6호
• /
• pp.377-383
• /
• 2006

The purpose of the present study was to examine the pharmacokinetic characteristics of arsenic hexaoxide($As_4O_6$), a novel anticancer compound, after i.v. bolus and oral administration in rats. We developed an ICP-Mass based method to analyze arsenic hexaoxide levels in plasma, bile, urine, feces, and tissue and validated the method. Arsenic hexaoxide rapidly disappeared from the plasma by 10 min($\alpha$ phase) after i.v. administration, which was followed by the late disappearance in the $\beta$ phase. The mean plasma half-lives($t_{1/2}$) of arsenic hexaoxide at the a and $\beta$ phase when administered at a dose of 5 mg/kg were 1.57 and 29.8 min, respectively. The maximum plasma concentration($C_{max}$) was 230 ng/mL, after oral administration of arsenic hexaoxide at a dose of 50 mg/kg. The bioavailability, which was calculated from the dose-adjusted ratio, of the oral administered arsenic hexaoxide was 1.61%. Of the various tissues tested, arsenic hexaoxide was mainly distributed in the spleen, lung, liver and kidney after oral administration. Arsenic hexaoxide levels in the spleen or lung at 24 hr after oral administration were higher than those of maximum plasma concentration($C_{max}$). The cumulative amounts of arsenic hexaoxide found in the urine by 48 hr after the administration of 50 mg/kg were 5-fold higher than those in the bile. However, the cumulative amounts in the feces were 10-fold higher compared with those of urine, suggesting that arsenic hexaoxide is mostly excreted in the feces. In conclusion, our observations indicated that arsenic hexaoxide was poorly absorbed from the gastro-intestinal tract to the blood circulation and transferred to tissues such as the spleen and lung at 24 hr after oral administration. Moreover, the majority of arsenic hexaoxide appears to be excreted in the feces by 48 hr after oral administration.

• 지질공학
• /
• 제24권4호
• /
• pp.643-648
• /
• 2014

터널의 굴착과정에서 막장전반부에 분포하는 절리를 예측하여 그들로 인한 붕괴를 예방하기위해 보강계획을 수립하는 것은 매우 중요한 사안이다. 그러나 빠른 굴착공정에서 절리의 분포를 충분히 조사하고 예측하는 것은 쉽지 않은 일이다. 본 연구는 굴착면 선단부에 분포하는 절리를 예측할 수 있는 새로운 통계적 기법을 제시하고자 한다. 제시될 방법은 단일 절리군에 대한 절리간격의 누적분포도를 이용한 절리분포의 예측이다. 누적분포도는 수평축에 절리를 동일간격으로 순차적 배열을 한 후, 수직축에 누적간격을 기준으로 각 절리를 하나의 점으로 표기한다. 이 도표에서, 표기된 점들이 선형을 이루면 절리의 분포양상이 규칙적임을 의미하며, 직선의 기울기는 절리의 간격을 의미한다. 기울기가 낮으면 절리사이의 간격이 적은 것 이다. 점들의 분포가 군집형을 이루면 이는 절리의 분포양상이 군집형을 이룸을 의미한다. 현장에서 조사된 자료를 누적분포도에 점기하면 특정 절리군에 대한 분포양상이 분포도에 표기될 것이고, 이 분포양상을 연장하면 앞으로 굴착될 굴착면 전방의 절리분포를 예측할 수 있을 것이다. 실 터널현장에서 10 m 간격에서 측정된 특정 절리군에 대한 누적분포도 분석이 수행되었으며 이를 기반으로 3 m 전방의 미 굴착구간에 대한 절리분포가 예측되었다. 예측결과를 실제 현장자료와 비교한 결과 누적분포도는 전방절리를 적절히 예측하고 있었다. 분포도의 특성상 점기된 절리들의 선형과 등간격의 군집형태는 그 자체로 절리의 분포가 규칙적이며 누적분포도의 예측이 정확할 수 있음을 의미하는 것이다. 그러므로 본 연구는 향후 누적분포도의 분포양상에 대한 고찰과 그 결과의 넓은 공유가 있기를 바란다.

• Restorative Dentistry and Endodontics
• /
• 제23권2호
• /
• pp.701-709
• /
• 1998

Many dental composites are Bis-GMA based resin which diluted with the more fluid monomer triethylenglycol dimethacrylate(TEGDMA). TEGDMA is often present in exess so that some quantity remains unreacted following photo-initiated polymerization. TEGDMA is a component of some resin composites which contributes to their cytotoxicity. The presence of dentin between resin composite and pulp space reduce the cytotoxicity in vitro. The root system from extrcted human third molar was removed and then a circular occlusal cavity 4mm in diameter was prepared, leaving a remaining dentinal thickness to the roof of the pulpal chamber within the range 1.0-1.5mm. Dentine was treated with 37% phosphoric acid prior to Z 100 placement without using bonding resin(group 1). In group 2, SMP(Scotchbond Multi Purpose) primer, bonding resin prior to Z 100 placement were applied sequently. In group 3, moulds with internal dimensions 4mm diameter by 2mm depth were used to contain the composite alone with an equvalent mass on tooth model, and then they were immersed directly into water. The purpose of this study is to evaluate the release rate and quantity of TEGDMA with or without the application of bonding resin. Both release rate and total cumulative amount of TEGDMA for the three groups were determined using reversed-phase HPLC at times up to 10 days. The results were as follows: 1. All experimental groups showed the highest rate of release was in the first sample period(0-4.32 min) and the rate of release declined exponentially thereafter. 2. The maximum release rate and total cumulative account of TEGDMA in the tooth model of group 1 and group 2 with the use of SMP bonding resin were reduced however ther were no significant differences between these groups(P>0.05). 3. In the first sample period(0-4.32 min), the rate of release of TEGDMA from composite resin in group 3 immersed directly into water was significantly higher than that in group 1 and group 2 of tooth model(P<0.05). Conclusively, TEGDMA diffusion from Z 100 resin was not effectively prevented by the presence of dentin in spite of using the SMP bonding resin.

• 유기물자원화
• /
• 제11권4호
• /
• pp.90-96
• /
• 2003

본 연구에서는 유류로 오염된 현장 주유소를 대상으로 토양증기추출 공정 적용시 연속추출과 간헐추출 운전의 효율성을 검토하였다. 공기주입 후 압력을 측정한 결과 동일 조건에서도 공기주입정 헤드(head) 압력이 상이하게 나타나 실험부지내 토양이 매우 불균일하다는 것을 알 수 있었다. 간헐식은 1시간 가동 후 3시간 정지시켰으며, 연속식은 50분 가동 후 10분 휴지하는 것을 연속추출한 것으로 가정하였다. 송풍기의 용량은 $1m^3/min$이었다. 추출모드의 영향실험은 오염농도가 심한 두 지점을 선정하여 실시하였으며, 48시간 동안 온라인 모니터링으로 측정한 TPHgas 농도를 적산하여 비교한 결과 1시간 가동 후 3시간 휴지한 간헐추출모드가 연속추출모드보다 높게 나타났다. 일반적으로 토양증기추출 공정이 장기간 가동된다는 점을 고려한다면 오염가스 휘발량, 전력비용, 그리고 시설의 감가상각비 등에서 볼 때 간헐추출모드로 운전하는 것이 연속추출모드 보다 더 유리할 것으로 판단된다.

• 한국통신학회논문지
• /
• 제25권6A호
• /
• pp.794-801
• /
• 2000

본 논문에서는 디지털 통신시스템의 성능 평가를 위한 효율적인 새로운 성능 평가 기법을 제안하고, 디지털 위성방송 채널에서의 수행시간의 획기적인 개선 효과를 제시하고 있다. 제안 알고리즘에서는 기존의 Importance Sampling 기법이 안고 있는 근본적인 문제점을 해결하기 위하여, 센트랄 모우멘트 기법을 도입 사용하였다. 즉, 채널 부/복호기를 제외한 내부채널의 수신단에서 잡음이 혼합된 수신신호의 센트랄 오우멘트를 측정하여 수신신호의 확률적인 특성, 즉 누적확률분포함수를 구하고 이를 이용하여 채널 부/복호기의 성능을 평가함으로서, 채널 전체의 성능을 단시간에 완료할 수 있다. 또, 디지털 위성방송 채널을 이용한 시뮬레이션 결과를 토대로 시뮬레이션 시간 측면에서 알고리즘의 효율을 보이고 있으며, 부호화기를 포함한 비선형 위성 채널과 M-dimensional memory에서의 Importance Sampling 기법이 갖고 있는 문제점을 제안된 알고리즘을 이용해 해결했음을 보여주고 있다.

• 한국물환경학회지
• /
• 제22권2호
• /
• pp.294-299
• /
• 2006

The Ministry of Environment in Korea has introduced Total Pollution Load Management System (TPLMS) in major 4 large rivers to protect the water quality from possible pollutants. In order to successfully achieve the TPLMS, the nonpoint source should be controled by applying the best management practices in highly polluted areas. Of the various nonpoint sources, the highways are stormwater intensive landuses because of its high imperviousness and high pollutant mass emissions. The EMC (Event Mean Concentration) is an important parameter to correctly determine the pollutant mass loadings from nonpoint sources. However, it has wide ranges because of various reasons such as first flush phenomenon, rainfall and watershed characteristics. Even though the EMC is closely related to the first flush phenomenon, the relationship have not proven until present. Therefore, in this paper, the dynamic EMC method will be introduced to clearly make the relationship between EMC and first flush phenomenon. Also by applying the dynamic EMC method to monitored data, we found that the highly concentrated stormwater runoff was washed off within 20~50 minutes storm duration. The first flush criteria for economical treatment was also determined to 5~10 mm (mean=7.4 mm) as a cumulative rainfall.