• 제목/요약/키워드: Crossover effect

검색결과 219건 처리시간 0.022초

DNA 크로스오버가 오리가미 구조물의 강도에 미치는 영향에 대한 유한요소법 기반 민감도 분석

  • 김경수
    • EDISON SW 활용 경진대회 논문집
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    • 제5회(2016년)
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    • pp.269-269
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    • 2016
  • DNA origami is the most fitting nano-technology for synthesis of complex nano-structures. DNA crossover which ties DNA helices together are the main reason for the stable sustenance of origami structures with respect to other nano-scale structures. The mechanical properties of DNA crossovers have profound connection with structural rigidity, and it is a known fact that the rigidity changes depending on the arrangement of crossovers. It is possible to control the rigidity of origami structures for functionality and furthermore extends the field of DNA origami application. Here, we investigate the effect of crossovers on 2-Dimensional DNA structures varying crossover arrangement by sensitivity analysis based on finite element model. The crossover properties obtained from this analysis are compared with the existing experimental results.

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공변량을 고려한 2×2 교차설계법에 평균 생물학적 동등성 평가 (Assessing Average Bioequivalence for 2×2 Crossover Design with Covariates)

  • 정규진;박상규;김관엽
    • 응용통계연구
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    • 제24권1호
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    • pp.161-167
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    • 2011
  • 소수의 피험자로 이루어지는 생물학적 동등성 시험에서 제제의 특성으로 인해 측정된 생체이용률이 크게 영향을 받는 경우 교차설계법을 사용하더라도 적절한 통제가 어려워지는 경우가 많다. 이 때 적절한 공변량을 통해 이러한 영향력을 통제할 수 있다면 공변량을 고려한 교차설계법 모형이 고려될 필요가 있다. 본 연구논문에서는 공변량을 갖는 $2{\times}2$ 교차설계법을 고려하고 제제간의 생물학적 동등성 평가를 위한 통계적 추론을 제안한다. 제안된 방법은 실제 사례를 통해 논의한다.

A Set-theoretic Account of English Crossover Effects

  • Lee, Gunsoo
    • 한국영어학회지:영어학
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    • 제1권1호
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    • pp.101-117
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    • 2001
  • In English, whether or not wh-movement creates weak crossover effects depends upon the type of wh-phrases that cross over. A bare interrogative like who shows a typical weak crossover effect whereas which N type (e.g. which girl) and partitive type (e.g. which of these girls) wh-phrases would show mere weaker and weakest crossover effects, respectively. Previous approaches to English crossover phenomena that resort to a binary notion of specificity or D-linking cannot account for the three-way contrast the three different types of wh-phrases show. To overcome this problem, I argue in this paper that specificity should be a non-binary set-theoretic notion and propose the following subset principle and optimal binding relation: Between two lexical nominal expressions A and B, A is regarded as more specific than B iff the denotation of A comes from a more narrowly defined non-singleton set than B. Between two lexical nominal expressions A and B, if A locally binds B, then the non-singleton set from which the denotation of A comes should be a subset of the set from which the denotation of B comes (i.e. B cannot be more specific than A). The smaller the subset (i.e. the wider the specificity gap between binder and binder), the more optimal the local binding relation is. A locally binds B iff A is coindexed with B, and A c-commands B, and there is no such C that does not bind A but binds B. Finally, I show that partitivity functions to carve out a smaller subset and thus make partitive wh-phrases more specific than simple which N type wh-phrases.

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Characterization of Methanol Crossover through Nafion Membranes by Direct Cell Performance Measurement

  • Park, Kyung-Won;Kim, Young-Min;Kwon, Bu-kil;Choi, Jong-Ho;Park, In-Su;Sung, Yung-Eun
    • 전기화학회지
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    • 제5권4호
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    • pp.226-231
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    • 2002
  • Power densities produced by the permeation of methanol through membranes were directly measured by inserting the membrane in front of anode in a membrane-electrode-assembly of a direct methanol fuel cell (DMFC). The power density was closely related to the loss of power in the DMFC and was strongly affected by temperature. As the cell temperature was increased, the power density resulting from methanol crossover was increased. The increase in methanol crossover had be attributed to diffusion caused or affected by temperature. Methanol crossover a major effect on the performance of a DMFC at a relatively low temperature with $26\%\;loss\;at\;30^{\circ}C$. In order to reduce methanol crossover, a conventional Nafion membrane was modified by the incorporation of Pt or Pd. The reduction in methanol crossover was investigated in these modified membranes by our cell performance measurement. Pt and Pd particles incorporated in the Nafion membranes block methanol pathway and prevent methanol transport through the membranes, which was proved by combining with liquid chromatography.

설계유형에 따른 향기요법의 효과 (Comparing the Effects of Aromatherapy on Dysmenorrhea by Research Design)

  • 최은희;서지영
    • 성인간호학회지
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    • 제22권1호
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    • pp.31-40
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    • 2010
  • Purpose: The purpose of this study was to examine whether there is difference in the effects of aromatherapy on dysmenorrhea by research design. Methods: Findings from the two different research designs (Nonequivalent control group pretest-posttest [NCG] design vs. two-group crossover design) were compared in regard to the effect of aromatherapy on dysmenorrhea. The subjects of the NCG design and the crossover design were a total of 58 female nursing students. The treatments (aroma essential oil inhalation and carrier oil inhalation) were given using a necklace. The data were analyzed by Fisher's exact test, t-test, Mann-Whitney test, paired t-test, and Shapiro-Wilk test using the SPSS/WIN 12.0 program. The effect size for the two research designs was calculated. Results: In both research designs, the level of dysmenorrhea and menstrual pain after the aroma treatment were not significantly different from those after the placebo treatment. The effect size of the NCG design was higher than that of the crossover design. Conclusion: Aroma inhalation may not be effective in managing dysmenorrhea and menstrual pain. In order to further clarify the efficiency of research design and the effect of aromatherapy on discomfort during menstruation, replication studies are necessary. Future studies need to examine the effects of different research design on non-interval variables.

침형 경피신경 전기자극법과 전통적인 경피신경 전기자극법의 교차효과 비교 (The Comparison of the Acupuncture-Like Transcutaneous Electrical Nerve Stimulation and Conventional Transcutaneous Electrical Nerve Stimulation in Crossover Effect)

  • 권수현;배은영;신영주;이재호
    • 한국전문물리치료학회지
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    • 제3권2호
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    • pp.29-35
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    • 1996
  • The purpose of this study was to compare acupuncture-like transcutaneous electrical nerve stimulation(ALTENS) with conventional transcutaneous electrical nerve stimulation(C-TENS) for crossover effect in healthy subjects. Forty subjects recieved ALTENS(20 persons), C-TENS(20 persons) to one upper extremity. Each technic was applied to the motor point of the wrist extensor muscle group for twenty-minutes. With the subject placed in supine the technics were applied at 80 Hz, 2-10 mA(ALTENS) and 10 Hz, 4-12 mA(C-TENS). Results revealed: (1) a significant difference between the pretreatment and posttreatment in each group(p<.05) (2) no significant difference between ALTENS and C-TENS(p>.05). In conclusion, there was no difference between ALTENS and C-TENS for crossover effect.

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PEMFC 고분자 막의 전기화학적 열화에 미치는 온도의 영향 (Effect of Temperature on Electrochemical Degradation of Membrane in PEMFC)

  • 이호;김태희;손익제;이종현;임태원;박권필
    • Korean Chemical Engineering Research
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    • 제47권4호
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    • pp.441-445
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    • 2009
  • 고분자전해질 막의 전기화학적 열화에 미치는 온도의 영향에 대해 연구하였다. 가속 열화 조건(OCV, anode 무가습, cathode 65% RH)에서 셀 온도를 변화시켜 144시간 운전한 후 셀 성능은 12에서 35%까지 감소하였다. 이러한 성능 감소는 FER(Fluoride Emission Rate) 측정에서 알 수 있듯이 과산화수소 혹은 산소라디칼(${\cdot}OH$, $HO_2{\cdot}$)의 공격에 의한 막의 열화에 따른 것으로 라디칼 형성을 위한 가스 crossover의 증가를 가져왔다. 전극에서의 라디칼 생성은 ESR로 확인하였다. 고분자막 열화의 온도 의존성을 나타내는 Arrhenius plot에 얻어진 활성화 에너지 값은 66.2 kJ/mol이었다. 셀 작동온도 증가는 라디칼 형성속도와 라디칼이 막을 공격하는 반응 속도뿐 아니라 가스 crossover 속도도 증가시켜 막 열화를 가속화시켰다.

국악장단을 적용한 크로스오버 음악활동이 유아의 다문화 인식에 미치는 영향 (The Effect of Crossover Musical Activities: Applying the Traditional Korean Jang-dan on the Multicultural Perception of Young Children)

  • 홍길회;윤혜자
    • 한국보육지원학회지
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    • 제10권2호
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    • pp.21-41
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    • 2014
  • 본 연구의 목적은 국악장단을 적용한 크로스오버 음악활동이 유아의 다문화 인식에 미치는 영향을 알아보기 위한 연구이다. 본 연구의 대상은 Y시에 위치한 J유치원의 만5세 1반(실험집단 21명)과 S유치원의 만5세 2반(비교집단 20명, 통제집단 20명)의 61명(남31명, 여 30명)이다. 실험집단에는 본 연구자가 개발한 국악장단을 적용한 크로스오버 음악활동을, 비교집단에는 국악중심 음악 활동을, 통제집단에는 5세 누리과정의 음악수업을 각각 20회기동안 적용하였다. 연구결과 다문화인식 하위요인 중 사후 문화개방성 점수와 사후 문화수용성 점수는 국악장단을 적용한 크로스오버 음악활동을 실시한 실험집단이 비교집단과 통제집단보다 통계적으로 유의미한 수준에서 더 높은 것으로 나타났으며, 사후 문화존중성은 국악중심 음악활동을 실시한 비교집단에서 통계적으로 유의미한 수준으로 더 높게 나타났다. 이러한 연구 결과는 국악장단을 적용한 크로스오버 음악활동은 유아의 다문화 인식의 하위요소인 문화개방성과 문화수용성의 인식 증진에 효과가 있음을 시사한다.

이단계 지분계획법의 오차제곱합 유도와 그 활용 (Derivation of error sum of squares of two stage nested designs and its application)

  • 김대학
    • Journal of the Korean Data and Information Science Society
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    • 제24권6호
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    • pp.1439-1448
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    • 2013
  • 확률화 블록계획법이나 교차된 이원분류표에 대한 분산분석과 오차제곱합의 성질은 널리 알려져있다. 본 논문에서는 인자에 따른 수준에 또 다른 인자들이 내포되어 있는 지분계획 특히 이단계 지분계획에 대하여 구조적 특징을 설명하고 오차제곱합의 성질에 대하여 살펴보았다. 또한 이단계 지분계획의 활용으로 크로스오버 계획을 소개하고 생물학이나 약학 등의 분야에서 많이 사용되는 동등성 검정의 신뢰구간 구축에 대하여 설명하였고 실제자료와 SPSS 통계 페키지를 이용하여 분석함으로서 응용성을 부각시켰다.

양생온도가 고로슬래그 콘크리트의 강도발현에 미치는 영향분석 (Effect of curing temperature and blast furnace slag concrete on concrete strength development)

  • 이규동;전명일;이창수;김동식
    • 한국재난정보학회 논문집
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    • 제2권1호
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    • pp.129-137
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    • 2006
  • The present work is attempt to evaluate the temperature dependence of blast furnace slag concrete(BFSC) based on the concrete strength cured with different curing temperatures and ages. A equivalent substitution index(ESI) was induced to explain temperature dependence of concrete quantitatively as well as concrete strength. The results from compressive strength showed substantial crossover effect. which is the phenomenon that the compressive strength cured at low temperature becomes stronger than the one cured at high temperature. The crossover effect found more definitely on BFSC than plain concrete.. The ESI became 1.1 and 1.0 for the BFSC cured at $20^{\circ}C$ and $30^{\circ}C$ after age of 56 days, respectively. Which means that the contribution to strength development of blast furnace slag per unit mass is stronger than that of the Portland cement. It was considered therefore that the optimum curing temperature for BFSC is $20^{\circ}C$.

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