• Title/Summary/Keyword: Cross-sectional factor

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High Prevalence of Helicobacter pylori Resistance to Clarithromycin: a Hospital-Based Cross-Sectional Study in Nakhon Ratchasima Province, Northeast of Thailand

  • Tongtawee, Taweesak;Dechsukhum, Chavaboon;Matrakool, Likit;Panpimanmas, Sukij;Loyd, Ryan A;Kaewpitoon, Soraya J;Kaewpitoon, Natthawut
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.18
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    • pp.8281-8285
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    • 2016
  • Background: Helicobacter pylori is a cause of chronic gastritis, peptic ulcer disease, and gastric malignancy, infection being a serious health problem in Thailand. Recently, clarithromycin resistant H. pylori strains represent the main cause of treatment failure. Therefore this study aimed to determine the prevalence and pattern of H. pylori resistance to clarithromycin in Suranaree University of Technology Hospital, Suranree University of Technology, Nakhon Ratchasima, Northeastern Thailand, Nakhon Ratchasima province, northeast of Thailand. Materials and Methods: This hospital-based cross-sectional study was carried out between June 2014 and February 2015 with 300 infected patients interviewed and from whom gastric mucosa specimens were collected and proven positive by histology. The gastric mucosa specimens were tested for H. pylori and clarithromycin resistance by 23S ribosomal RNA point mutations analysis using real-time polymerase chain reactions. Correlation of eradication rates with patterns of mutation were analyzed by chi-square test. Results: Of 300 infected patients, the majority were aged between 47-61 years (31.6%), female (52.3%), with monthly income between 10,000-15,000 Baht (57%), and had a history of alcohol drinking (59.3%). Patient symptoms were abdominal pain (48.6%), followed by iron deficiency anemia (35.3%). Papaya salad consumption (40.3%) was a possible risk factor for H. pylori infection. The prevalence of H. pylori strains resistant to clarithromycin was 76.2%. Among clarithromycin-resistant strains tested, all were due to the A2144G point mutation in the 23S rRNA gene. Among mutations group, wild type genotype, mutant strain mixed wild type and mutant genotype were 23.8%, 35.7% and 40.5% respectively. With the clarithromycin-based triple therapy regimen, the efficacy decreased by 70% for H. pylori eradication (P<0.01). Conclusions: Recent results indicate a high rate of H. pylori resistance to clarithromycin. Mixed of wild type and mutant genotype is the most common mutant genotype in Nakhon Ratchasima province, therefore the use of clarithromycin-based triple therapy an not advisable as an empiric first-line regimen for H. pylori eradication in northeast region of Thailand.

Prevalence of Hyperhomocysteinemia and Related Factors in a Community-based Health Examination Survey: A Cross-sectional Study (경기도 일개 지역사회 대표집단에서 고호모시스테인혈증의 유병률 및 관련요인에 대한 단면조사연구)

  • Kim, Soo-Jeong;Lim, Kyung-Sook;Song, Mi-Sook;Kang, Yeon-Ji;Lee, Soon-Young
    • Journal of Preventive Medicine and Public Health
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    • v.42 no.5
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    • pp.337-342
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    • 2009
  • Background : Many previous studies have shown that elevated homocysteine in the serum is a well known risk factor for cardiovascular disease and this is associated with other risk factors for cardiovascular disease, but any Korean data on this is limited. Objectives : This study aimed to calculate the prevalence of hyperhomocysteinemia and to analyze the relation between elevated homocysteine and the lifestyle factors of Korean adults. Methods : We conducted a cross-sectional survey that included 650 men and 743 women (age range, 20 to 79 years) who were residents of Gwangju City in Gyeonggi-do. These subjects participated in the health interview and examination survey from November to December 2005. The total homocysteine, total cholesterol, HDL-cholesterol, LDL-cholesterol, and triglyceride in the serum were measured. All the participants had their body composition measured such as height and weight, and we obtained health-related behavioral information through the self-entry questionnaire. Results : Very right-handed skewed distributions of homocysteine were shown in men and women. The prevalence of hyperhomocysteinemia was 22.6% in men and 13.7% in women in Gwangju city. On the multiple logistic regression analysis, hyperhomocysteinemia was associated with age (OR=1.02, 95% CI=1.01-1.04), male gender (OR=1.60, 95% CI=1.02-2.52), severe general physical activity (OR=0.32, 95% CI=0.15-0.69) and nutrient consumption (OR=0.49, 95% CI=0.31-0.76). Conclusions : There is a great prevalence of hyperhomocysteinemia in adults of Gwangju City, Korea and it was associated with both genetic factors and lifestyle risk factors. This study can suggest that comprehensive lifestyle modification is needed in order to diminish the prevalence of hyperhomocysteinemia and to prevent CVD.

Factors Influencing Nursing Students' Social Distancing for COVID-19 Prevention (간호대학생의 COVID-19 감염 예방을 위한 사회적 거리두기 영향요인)

  • Jo, Eun Bi;Hwang, Cho Rong;Yu, Jae Oak;Shin, Hyeon Jin;Kim, Yu Jin;Choi, A Ron;Lee, Hanna
    • Journal of East-West Nursing Research
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    • v.26 no.2
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    • pp.167-175
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    • 2020
  • Purpose: This study aims to understand the effect of attitudes toward COVID-19, subjective norms, and intentions toward social distancing as a preventative measure for COVID-19 in nursing university students, and to provide basic data for COVID-19 prevention. Methods: A cross-sectional study design was used in this study. The participants included 169 nursing students at a university in G city. Data were collected from 22 May 2020 to 1 June 2020. A self-report questionnaire was used. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficients, and multiple regression analyses with the IBM/SPSS 26.0 for Window Program. Results: Intention was the most influential factor on social distancing (β=.29, p=.002), followed by the number of breakfasts per week (β=.18, p=.005), school grade (β=-.16, p<.001), and smoking status (β=-.13, p=.046). These variables explained 35.0% of factors influencing social distancing (F=12.24, p<.001). Conclusion: The results of this study are meaningful and present a direction for nursing students and future medical personnel to effectively perform social distancing. It is necessary to educate nursing students so that they can practice proper health care habits and intentions for social distancing.

Experimental Study on the Characteristics of Heat and Mass Transfer on the Teflon Coated Tubes (테프론 코팅 전열관 표면으로의 열 및 물질 전달 특성에 관한 실험적 연구)

  • Lee, Jang-Ho;Kim, Hyeong-Dae;Kim, Jung-Bae;Kim, Moo-Hwan
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.27 no.8
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    • pp.1051-1060
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    • 2003
  • The heat and mass transfer on two kinds of tube surfaces (bare stainless steel tube and Teflon coated tube) in steam-air mixture flow are experimentally studied to obtain design data for the heat exchanger of the latent heat recovery from flue gas. In the test section, 3-tubes are horizontally installed, and steam-air mixture is vertically flowed from the top to the bottom. The pitch between tubes is 67mm, the out-diameter of tube is 25.4mm, and the thickness is 1.2mm ; blockage factor (cross sectional tube area over the cross sectional area of the test section) is about 0.38. All of sensors and measurement systems (RTD, pressure sensor, flow-meter, relative humidity sensor, etc.) are calibrated with certificated standard sensors and the uncertainty for the heat transfer measurement is surveyed to have the uncertainty within 7%. As experimental results, overall heat transfer coefficient of the Teflon (FEP) coated tube is degraded about 20% compared to bare stainless tube. The degradation of overall heat transfer coefficient of Teflon coated tube comes from the additional heat transfer resistance due to Teflon coating. Its magnitude of heat transfer resistance is comparable to the in-tube heat transfer resistance. Nusselt and Sherwood numbers on Teflon (FEP) coated surface and bare stainless steel surface are discussed in detail with the contact angles of the condensate.

The Association of High Sensitivity C-reactive Protein(hsCRP) with Hypertension in Some Rural Residents (일부 농촌지역 주민의 High Sensitivity C-reactive Protein(hsCRP)과 고혈압의 관련성)

  • Lee, Young-Seon;Park, Jong;Kang, Myeong-Guen;Kim, Ki-Soon;Ryu, So-Yeon
    • Journal of Preventive Medicine and Public Health
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    • v.38 no.3
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    • pp.325-329
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    • 2005
  • Objectives : This study was performed to assess the association between high sensitivity C-Reactive Protein (hsCRP) and hypertension. Methods : We evaluated the relationship between hsCRP with hypertension and other cardiovascular risk factors, using a cross-sectional survey of 202 people over the age of 50, living in a rural area. A logistic regression analysis was used to study the association between hsCRP and hypertension. The hsCRP levels were divided in quartiles, and the odds ratios (OR), with 95% confidence intervals (95% CI), calculated, using the lowest quartile as a reference. Results : The subjects consisted of 37.1% men and 62.9% women, with a mean (SD) hsCRP level of $1.9({\pm}3.0mg/{\ell})$ . The overall prevalence of hypertension was 61.4%. The prevalence of hypertension according to the hsCRP quartile was not statistically significant. After adjustment for confounding variables, the prevalence of hypertension according to the subjects in the 2nd, 3rd and 4th hsCRP quartiles were 1.418 (95% CI=0.554-3.628), 1.124 (95% CI=0.392-3.214) and 0.892 (95% CI=0.312-2.547) times higher, respectively, compared to those in the 1st quartile. Conclusions : The results showed that the level of hsCRP was not a risk factor for hypertension among adults aged over 50 years, living in a rural area. A further study should be performed to find the association between hsCRP and hypertension.

Critical Loads and Post-Buckling Behaviour of Simply Supported Tapered Columns (단순지지(單純支持) 변단면(變斷面) 기둥의 임계하중(臨界荷重) 및 후좌굴(後挫屈) 거동(擧動))

  • Lee, Byoung Koo;Oh, Sang Jin;Mo, Jeong Man
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.11 no.4
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    • pp.17-26
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    • 1991
  • Numerical methods are developed to obtain the critical loads and to analyze the post-buckling behaviour of the linearly varying tapered columns. The non-dimensional differential equations governing the elastica of post buckled column are derived by third order and solved numerically using the Runge-Kutta method and Regula-Falsi method. Three kinds of cross-sectional shape with simply supported end constraint are applied in unmerical examples. As the numerical results, the equlibrium paths. the typical elastica of post buckled columns and the critical load vs. section ratio curves are presented in figures. Also, the effects of cross-sectional shape factor on critical loads and postbuckling behaviour are presented in tables.

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Investigation of Coastal Erosion Status in Geojin Port Area (거진항 일대의 해안 침식 현황 조사 연구)

  • Kim, In-Ho;Song, Dong-Seob
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.30 no.1
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    • pp.67-73
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    • 2012
  • Coastal erosion and its impact on human activities as well as the economic damage and environmental conservation of coastal area is one of major concern in the national policies. In this study, we conducted physical investigations to evaluate effects of erosion in the Geojin beach, which is located nearby the Geojin Port, for a detecting of shoreline change and beach cross-sectional area. The results showed that significant coastal erosion of the Geojin beach has occurred by the complex resources of natural factor, such as rising sea level, storm surges, high wave, and man-made construction. Especially, due to the sand supplement from Jasan river, the section which is nearby the estuary of Jasan river is maintained as a stable beach, whereas beach erosion of the other site in GW04 section has been increased indeed. Therefore, we suggest that it is need to continuous monitoring using DGPS and various surveying techniques to prevent beach erosion onto the GW04 section.

Optimum topology design of geometrically nonlinear suspended domes using ECBO

  • Kaveh, A.;Rezaei, M.
    • Structural Engineering and Mechanics
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    • v.56 no.4
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    • pp.667-694
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    • 2015
  • The suspended dome system is a new structural form that has become popular in the construction of long-span roof structures. Suspended dome is a kind of new pre-stressed space grid structure that has complex mechanical characteristics. In this paper, an optimum topology design algorithm is performed using the enhanced colliding bodies optimization (ECBO) method. The length of the strut, the cable initial strain, the cross-sectional area of the cables and the cross-sectional size of steel elements are adopted as design variables and the minimum volume of each dome is taken as the objective function. The topology optimization on lamella dome is performed by considering the type of the joint connections to determine the optimum number of rings, the optimum number of joints in each ring, the optimum height of crown and tubular sections of these domes. A simple procedure is provided to determine the configuration of the dome. This procedure includes calculating the joint coordinates and steel elements and cables constructions. The design constraints are implemented according to the provision of LRFD-AISC (Load and Resistance Factor Design-American Institute of Steel Constitution). This paper explores the efficiency of lamella dome with pin-joint and rigid-joint connections and compares them to investigate the performance of these domes under wind (according to the ASCE 7-05), dead and snow loading conditions. Then, a suspended dome with pin-joint single-layer reticulated shell and a suspended dome with rigid-joint single-layer reticulated shell are discussed. Optimization is performed via ECBO algorithm to demonstrate the effectiveness and robustness of the ECBO in creating optimal design for suspended domes.

A Cross-Sectional Satisfaction Survey of 845 Traffic Accident Patients Treated with Korean Medicine

  • Kim, No H.;Lee, Yoon J.;Suh, Chang Y.;Lee, Gi B.;Yang, Kyu J.;Kim, Tae-Gyu;Gi, Yu-Mi;Kwon, Mijung;Ha, In-Hyuk
    • Journal of Acupuncture Research
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    • v.35 no.2
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    • pp.69-74
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    • 2018
  • Background: We conducted a cross-sectional study to analyze the pain characteristics and satisfaction scores in traffic accident (TA) patients seeking Korean medicine treatment. Methods: A survey was conducted in 845 outpatients who visited 10 Korean medicine institutions due to TA-associated symptoms from February 25th, 2016 to March 9th, 2016. The questionnaire included information about patient sociodemographic characteristics, accident circumstance details, pain levels, treatment methods, satisfaction and pre-existing musculoskeletal disorders. All statistical analyses were performed using STATA 14.0. Results: A total 754 of the 845 respondents had experienced acute pain of onset within 1-2 days. Pain in the neck or low back was most common, and low back pain (LBP) was more prevalent in pedestrian-vehicle accident cases. Patients showed highest satisfaction with pharmacopuncture treatment, followed by acupuncture and Chuna manual therapy. Although treatments were not completed at the time of the survey, the majority of patients were satisfied with the Korean medicine treatments they received and indicated their intent to reuse this treatment in the future. The degree of pain reduction after treatment was a factor that influenced patient satisfaction with and intention to reuse Korean medicine. Conclusion: This study determined the characteristics and status of TA patients using Korean medicine and suggests the need for further more inclusive studies.

A Study on the Major Microeconomic Factors for the Advertisement Market and the Financial Policy for Digital Contents (광고시장 규모결정 요인에 대한 미시경제학적 접근 및 콘텐츠 산업 재원정책 연구)

  • Byun, Sangkyu
    • Journal of Digital Contents Society
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    • v.13 no.4
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    • pp.591-600
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    • 2012
  • Variety media based on the digital technology have emerged from the beginning of the 21th century and have competed with the traditional media in the advertisement market. With the high dependency upon the advertisement market, the Korean media industry has the urgent demand to increase it's pie. Korea regulator allowed PPL and private representatives, which resulted in low outcome. This study analysed the decision factors for the advertising market with the cross-sectional microeconomic data for 28 countries in OECD. The service industry, tax and GDP per capita affect negatively to the market growth rate, and unemployment positively. Therefore the market's growth speed would be slow down and the share of TV decreased. Therefore the two policies were suggested, increasing the direct payment by the audiences and retire of the inefficient broadcasters.