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Mapping of Quantitative Trait Loci on Porcine Chromosome 7 Using Combined Data Analysis

  • Zuo, B.;Xiong, Y.Z.;Su, Y.H.;Deng, C.Y.;Lei, M.G.;Zheng, R.;Jiang, S.W.;Li, F.E.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.10
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    • pp.1350-1353
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    • 2004
  • To further investigate the regions on porcine chromosome 7 that are responsible for economically important traits, phenotypic data from a total of 287 F2 individuals were collected and analyzed from 1998 to 2000. All animals were genotyped for eight microsatellite loci spanning the length of chromosome 7. QTL analysis was performed using interval mapping under the line-cross model. A permutation test was used to establish significance levels associated with QTL effects. Observed QTL effects were (chromosomewide significance, position of maximum significance in centimorgans): Birth weight (<0.01, 3); Carcass length (<0.05, 80); Longissimus muscle area (<0.01, 69); Skin percentage (<0.01, 69); Bone percentage (<0.01, 74); Fat depths at shoulder (<0.05, 54);Mean fat depth (<0.05, 81); Moisture in m. Longissimus Dorsi (<0.05, 88). Additional evidence was also found which suggested QTL for dressing percentage and fat depths at buttock. This study offers confirmation of several QTL affecting growth and carcass traits on SSC7 and provides an important step in the search for the actual major genes involved in the traits of economic interest.

Performance Analysis of Signal Acquisition in L2C Assisted GPS Receivers (L2C AGPS 수신기의 신호 획득 성능 분석)

  • Song, Seung-Hun;Park, Ji-Won;Park, Ji-Hee;Sung, Tae-Kyung
    • Journal of Institute of Control, Robotics and Systems
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    • v.17 no.1
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    • pp.61-67
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    • 2011
  • The GPS new civil signal is modulated on the L2 carrier at a frequency of 1227.6MHz. The L2C signal is composed of two multiplexed code signals, which include CM code with a 10,230 chip sequency repeating every 20ms, and CL code which has a 767,250 chip sequency repeating every 1.5 seconds. Thus, the new civil signal have much improved cross correlation properties so that the position fixing can be possible even with very weak signals. However, it requires very long acquisition time because of its long code length. This paper presents an efficient signal acquisition method for L2C AGPS receiver. Snapshot mode and coarse time assistance are assumed and total integration time is given by 1.5 sec. By SNR worksheet and computer simulation, it is proven that L2C signal can be acquired with very weak power less than -150dBm. Considering the acquisition time and the sensitivity, it is recommended that the highest power signal is acquired with CM code first to reduce TTFF. By the timing synchronization, at this time, search space of the code phase for other signals can be greatly reduced so that CL code can be used in signal acquisition to maximize sensitivity with small computation.

Development of Mobile Application for Cadastre Information Service (지적정보 서비스 모바일 애플리케이션 개발)

  • Lee, Geun-Sang;Kim, Hyoung-Jun
    • Journal of the Korean Association of Geographic Information Studies
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    • v.15 no.4
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    • pp.55-64
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    • 2012
  • This study developed a mobile application system for serving cadastral information needed to propel diverse cadastral works including cadastral resurvey efficiently. First, BlackPoint-Xr was selected as a spatial client engine to embody the cadastral information system based on mobile device including smart phone and tablet PC. The mobile cadastral information system contains functions such as finding location with GPS based on spatial information such as aerial photo, cadastral map, administrative map, and digital map, parcel search with address and lot number, finding land register including land address, the classification of land, and land price. Especially, this study developed functions which can analyze the measurement of distance, area, slope and cross-section elevation of land to apply construction work and land maintenance project. This system can support efficiently cadastral work and construction project by serving diverse cadastral information to users in field and can be also applied to the field of digital cadastral information.

Pattern Recognition of Ship Navigational Data Using Support Vector Machine

  • Kim, Joo-Sung;Jeong, Jung Sik
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.15 no.4
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    • pp.268-276
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    • 2015
  • A ship's sailing route or plan is determined by the master as the decision maker of the vessel, and depends on the characteristics of the navigational environment and the conditions of the ship. The trajectory, which appears as a result of the ship's navigation, is monitored and stored by a Vessel Traffic Service center, and is used for an analysis of the ship's navigational pattern and risk assessment within a particular area. However, such an analysis is performed in the same manner, despite the different navigational environments between coastal areas and the harbor limits. The navigational environment within the harbor limits changes rapidly owing to construction of the port facilities, dredging operations, and so on. In this study, a support vector machine was used for processing and modeling the trajectory data. A K-fold cross-validation and a grid search were used for selecting the optimal parameters. A complicated traffic route similar to the circumstances of the harbor limits was constructed for a validation of the model. A group of vessels was composed, each vessel of which was given various speed and course changes along a specified route. As a result of the machine learning, the optimal route and voyage data model were obtained. Finally, the model was presented to Vessel Traffic Service operators to detect any anomalous vessel behaviors. Using the proposed data modeling method, we intend to support the decision-making of Vessel Traffic Service operators in terms of navigational patterns and their characteristics.

Parental Factors Associated with Smartphone Overuse in Preschoolers: A Systematic Review and Meta-Analysis (유아의 스마트폰 과다사용과 관련한 부모요인 규명: 체계적 고찰 및 메타분석)

  • Lee, Gumhee;Kim, Sungjae;Yu, Heajin
    • Journal of Korean Academy of Nursing
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    • v.50 no.3
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    • pp.349-368
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    • 2020
  • Purpose: This study aimed to identify parental factors associated with smartphone overuse in preschoolers. Methods: A systematic review was conducted according to PRISMA guidelines. Relevant studies published in peer-reviewed journals from 2009 to June 2019 were identified through systematic search in 10 electronic databases (PubMed, CINAHL, Cochrane Central, EMBASE, Web of Science, NDSL, KISS, KMbase, KoreaMed, and RISS). Standardized effect sizes were calculated to quantify the associations of parental factors with smartphone overuse in preschoolers using meta-analysis. Results: A total of 30 cross-sectional studies involving 7,943 participants met the inclusion criteria. The following were negatively correlated with smartphone overuse in preschoolers: mother's parenting self-efficacy (r=-.35), mother-child attachment (r=-.28), mother's positive parenting behavior (r=-.28), mother's positive parenting attitude (r=-.25), and father's parenting involvement (r=-.15). Further, maternal factors such as smartphone addiction tendency (r=.41), parenting stress (r=.40), negative parenting behavior (r=.35), negative parenting attitude (r=.14), smartphone usage time (r=.26), employment status (r=.18), and age (r=.12) were positively correlated with smartphone overuse in preschoolers. Conclusion: Several parental factors influence smartphone overuse in preschoolers. These findings emphasize the need to assess and enhance the parental factors identified in this study to prevent smartphone overuse in preschoolers. Accordingly, we recommend the development of preventive interventions to strengthen parent-related protective factors and mitigate risk factors.

A Study on the Redesign of the Two-Stage Axial Compressor for Helicopter Engines (헬리콥터용 2단 축류압축기의 재설계에 관한 연구)

  • Kim, Jin-Han;Choi, Chang-Ho;Kim, Chul-Taek;Yang, Sooseok;Lee, Daesung
    • The KSFM Journal of Fluid Machinery
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    • v.4 no.1 s.10
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    • pp.7-13
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    • 2001
  • In developing a multistage compressor, the stage matching is one of the critical design issues. The mismatching can be often observed even if each stage has been proven good and then used as part of a compression system. A good matching among the stages can be achieved by changing various design parameters (i.e., passage cross sectional areas, blades angles, stagger angles, curvature, solidity, etc.). Therefore, designers need to find out what parameters must be changed and how much. In this study, a method to search the design parameters for optimum stage matching has been used based on an 1-D mathematical model of a compressor, which uses the data obtained from the preliminary test to identify the design parameters. This methodology is applied with a two-stage axial compressor, which was originally designed for a helicopter gas turbine engine. After identifying design parameters using preliminary test data, an optimization process has been employed to achieve the best matching between the stages (i.e., maximum efficiency of the compressor at its operation modes within a given range of the rotor speed under given restrictions for required stall margins and mass flow). 3-D flow calculations have been performed to confirm the usefulness of the corrections based on the 1-D mathematical model. Calculational results agree well with the experimental data in view of the performance characteristics. Some promising results were produced through the methodology proposed in this paper in conjunction with flow calculations.

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Development of an evidence-based clinical imaging diagnostic guideline for implant planning: Joint recommendations of the Korean Academy of Oral and Maxillofacial Radiology and National Evidence-based Healthcare Collaborating Agency

  • Kim, Min-Ji;Lee, Sam-Sun;Choi, Miyoung;Ha, Eun Ju;Lee, Chena;Kim, Jo-Eun;Heo, Min-Suk
    • Imaging Science in Dentistry
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    • v.50 no.1
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    • pp.45-52
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    • 2020
  • Purpose: This study was conducted to develop an evidence-based clinical imaging diagnostic guideline for implant planning, taking into account efficacy, benefits, and risks. Materials and Methods: The guideline development process employed the adaptation methodology used for Korean clinical imaging guidelines(K-CIG). Core databases(Ovid-Medline, Ovid-Embase, National Guideline Clearinghouse, Guideline International Network) and domestic databases (KoreaMed, KMbase, and KoMGI) were searched for guidelines. The retrieved articles were analyzed by 2 reviewers, and articles were selected using well-established inclusion criteria. Results: The search identified 294 articles, of which 3 were selected as relevant guidelines. Based on those 3 guidelines, 3 recommendations for implant planning were derived. Conclusion: We recommend radiography or cone-beam computed tomography (CBCT) scanning for individual patients judged to require a cross-sectional image after reading of a panoramic X-ray image and a conventional intraoral radiological image. Various steps should be taken to raise awareness of these recommendations among clinicians and the public, and K-CIG should be regularly reviewed and revised.

Characterization of Bacillus anthracis proteases through protein-protein interaction: an in silico study of anthrax pathogenicity

  • Banerjee, Amrita;Pal, Shilpee;Paul, Tanmay;Mondal, Keshab Chandra;Pati, Bikash Ranjan;Sen, Arnab;Mohapatra, Pradeep Kumar Das
    • CELLMED
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    • v.4 no.1
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    • pp.6.1-6.12
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    • 2014
  • Anthrax is the deadly disease for human being caused by Bacillus anthracis. Instantaneous research work on the mode of infection of the organism revealed that different proteases are involved in different steps of pathogenesis. Present study reports the in silico characterization and the detection of pathogenic proteases involved in anthrax infection through protein-protein interaction. A total of 13 acid, 9 neutral, and 1 alkaline protease of Bacillus anthracis were selected for analysing the physicochemical parameter, the protein superfamily and family search, multiple sequence alignment, phylogenetic tree construction, protein-protein interactions and motif finding. Among the 13 acid proteases, 10 were found as extracellular enzymes that interact with immune inhibitor A (InhA) and help the organism to cross the blood brain barrier during the process of infection. Multiple sequence alignment of above acid proteases revealed the position 368, 489, and 498-contained 100% conserved amino acids which could be used to deactivate the protease. Among the groups analyzed, only acid protease were found to interact with InhA, which indicated that metalloproteases of acid protease group have the capability to develop pathogenesis during B. anthracis infection. Deactivation of conserved amino acid position of germination protease can stop the sporulation and germination of B anthracis cell. The detailed interaction study of neutral and alkaline proteases could also be helpful to design the interaction network for the better understanding of anthrax disease.

A Study of th Optimum of closed ${CO}_{2}$ Gas Turbine Process for Nuclear Energy Power Plant(II) - For Optimal Design of Heat Exchanger- (원자력 발전소에 대한 밀폐 ${CO}_{2}$ 가스터빈 프로세스의 최적화 연구 (II) -열교환기의 설계에 관하여 -)

  • 이찬규;이종원
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.14 no.1
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    • pp.251-258
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    • 1990
  • Optimal design of heat exchanger for closed CO$_{2}$ gas turbine plant of three processes selected from the result of cycle analysis have been discussed previously paper(I) has been carried out under specified inlet and outlet conditions. Independent variables such as number of parallel connection, tube diameter, shell side and tube side pressure loss as well as dependent variables such as shell diameter, number of tubes, number of serial connections were all characterized according to the standardization or so. Search method was used to construct a computer simulation together with the calculation of heat transfer rate by logarithmic mean temperature difference method. Strength analysis of major parts was carried to examine their dimensions satisfying heat transfer and pressure loss requirements.

A Search on the Spatial Orientation in Flight (비행시 공간정위 유지에 대한 고찰)

  • Gu, Bon-Sool
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.2
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    • pp.139-182
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    • 1994
  • 조종사들은 비행시에 일상 생활 환경에서는 경험하지 못하는 여러가지 적대환경에 폭로된다. 이러한 환경에서는 인체의 평형기관은 실제와 일치하지 않는 정보를 제공해 주는 경우가 허다하다. 예를들면, 내이의 미로 전정기관이나 피하압력기관기 등은 항공기의 기동으로 발생하는 중력과 지구의 중력을 구별 하지 못하는 기능의 한계성때문에 계기비행하에서는 대개의 경우 공간정위상실, 즉 비행착각을 유발한다. 이 착각으로 인한 항공기 사고는 통계상에서 상당 부분이 치명사고로 나타나고 있는데, 이러한 사실은 비행착각현상이 비행안전에 극히 위험한 요소가 되고 있다는 것을 실증한다고 할 수 있다. 그러므로 조종사들은 비행시 공간정위 유지를 위한 철저한 대비가 있어야 한다. 공간정위 상실현상이 잘 발생하는 경우는 야간이나 기타 계기비행 환경에서 주위시각이 제약을 받을 때이다. 즉, 계기비행 환경에서의 편대비행시나 고기동시, 그리고 대조물이 모호한 야간의 활주로에서 이착륙할때 등을 들 수 있다. 비행시 공간정위 상실현상을 예방하기 위해서는 첫째로 이러한 유형의 사고분석자료를 토대로 하여 항공기의 설계단계에서부터 제작에 이르기까지 착각을 유발할 수 있는 구조적 요인을 제거해야 한다. 둘째로는 이러한 착각을 유발하지 않는 운항이나 기동방식을 택하여 비행임무를 수행토록 해야한다. 세째로 조종사들은 이러한 착각을 정상적인 인체의 반응에 의한 것이므로 자신에게도 당연히 일어난다는 사실을 용인해야 한다. 네째로 조종사들은 계기비행에 대한 구체적이고 실제적인 훈련을 통하여 계기비행 경험을 쌓아야 한다. 다음은 조종사들의 실제비행시 공간정위 상실현상에 봉착했을때의 처리요령이다. 첫째로 계기비행상황에서 자신의 감각과 계기가 일치하지 않을 때는 즉시 계기를 Cross Check하여 항공기의 자세나 기동형태를 정확하게 파악해야 한다. 둘째로 계기가 조종사의 의도대로 나타나도록 조작하고 이를 철저하게 의지하고 믿어야 한다. 세째로 자신의 감각과 계기가 일치할때까지 수평비행을 유지해야 한다. 그리고 마지막으로, 고성능 항공기가 계기비행중 저공에서 비행착각에 봉착하게 될때의 행동절차를 철저하게 숙지하고 있어야 한다.

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