• Journal of Preventive Medicine and Public Health
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• v.33 no.3
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• pp.343-348
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• 2000

Objectives : This study was conducted to integrate the results of studies assessing the association between chronic noise exposure and blood pressure. Methods : Using a MEDLINE search with noise exposure, blood pressure and hypertension as key words, we retrieved articles from the literature that were published from 1980 to December 1999. The criteria for quality evaluation were as follows: 1) the study subjects must have been workers employed at a high noise level area 2) The paper should use average and cumulative noise exposure as method for exposure evaluation. 3) Blood pressure in each article should be reported in a continuous scale Among the 77 retrieved articles, six studies were selected for quantitative meta-analysis. Before the integration of the regression coefficients for the association between blood pressure and noise level, homogeneity tests were conducted. Results : All studies were a cross-sectional design and the study subjects were industrial workers. Five papers used a time-weighted average for noise exposure and only one paper calculated the cumulative noise exposure level. The measurement of blood pressure in the majority of studios were accomplished in a resting stale, and used an average of two or more readings. The homogeneity of studies was rejected in a fixed effect model, so we used the results in a random effect model. The results of the quantitative meta-analysis, the weighted regression coefficient of noise associated with systolic blood pressure and diastolic blood pressure were 0.05 (95% confidence interval [CI]: -0.03, 0.13) and 0.06 (95% CI: -0.01, 0.13), respectively. Conclusions : Our results suggested that chronic exposure to industrial noise does not cause elevated blood pressure.

• Journal of Preventive Medicine and Public Health
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• v.37 no.1
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• pp.59-71
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• 2004

Objectives: This study aimed to measure the disability weights for the Korean Burden of Disease study, and to compare them with those adopted in the Australian study to examine the validity and describe the distinctive features. Methods : The standardized valuation protocol was developed from the Global Burden of Disease (GBD) study and the Dutch Disability Weights study. Disability weights were measured for 123 diseases of the Korean version of Disease Classification by three panels of 10 medical doctors each. Then, overall distribution, correlation coefficients, difference by each disease, and mean of differences by disease group were analyzed for comparison of disability weights between the Korean and Australian studies. Results : Korean disability weights ranged from 0.037 to 0.927. While the rank correlation coefficient was moderate to high ($r_s$=0.68), Korean disability weights were higher than the corresponding Australian ones in 79.7% of the 118 diseases. Of these, war, leprosy, and most injuries showed the biggest differences. On the contrary, many infectious and parasitic diseases comprised the greater part of diseases of which Korean disability weights were lower. The mean of the differ ences was the highest in injuries of GBD disease groups, and in cardiovascular disease, injuries, and malignant neoplasm of the Korean disease category. Conclusions : Korean disability weights were found to be valid on the basis of overall distribution pattern and correlation, and are expected to be used as basic data for broadening the scope of burden of disease study. However, some distinctive features still remain to be explored in following studies.

• Korean Journal of Plant Resources
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• v.13 no.1
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• pp.1-10
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• 2000

Pecan is deciduous tree and belongs to the Julandaceae family. Pecan is an economically important as a nut and timber crop. Heterozygosity is expected to be high for typically cross-pollinated. Yet little is known about the nature of genetic variation within this species. In addition, the pedigree of many pecan cultivars remains unknown or is questionable. In this study, the phylogenetic relationships between 22 pecan cultivars and its analyzed by RAPD (randomly amplified polymorphic DNA). PCR Amplification used 40 randomly selected oligoes as primers. Based on their genetic similarities derived from the RAPD data, the 22 pecan cultivars were classified into different five groups in agarose gel. The 22 pecan cultivars were classified into five sectional groups by UPGMA clustering analysis, too. C. flacra and Black walnut showed the 0.9 of similarity index and Farley, Pawnee showed the 0.85 of similarity index. The 22 pecan cultivars were classified into different five groups by analysis of the 4% polyacrylamide gel fraction. (Group I : 1, 2, 3, 4, 13, 16, 17, 20, 21 Group II : 14,18 GroupIII : 6,12 GroupIV : 5, 11, 15, 19, 22 CroupV : 7, 8, 9, 10) Group V show the 1.0 of similarity index and Farley, Sturya, Clarke, Pawnee show the 0.98 of similarity index and Kiowa, Schley show the 0.92 of similarity index. Results from this study indicated that RAPD can be used to establish the genetic relationships among the 22 pecan cultivars. Similarity coefficients generally agreed with what would be predicted in cultivars with known pedigrees, and we could accurately construct relationships among cultivars. In addition, we have shown that RAPD provides useful information on the origin of unknown cultivars.

• Explosives and Blasting
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• v.16 no.4
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• pp.29-39
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• 1998

A case study was made on in site vibration velocity data collected for two months in the construction area of the Daeduck cultural City Hall. Taegu The geology over the area shows distributions of weathered and some crack developed hornfels of mud-shale in the upper part, underlain by less weathered and hard compact quartzite. For the period of 2 months of blasting event, the vibration velocities were measured and these data were analysed for K and n for three different period the test period, first month and second month. The data for the test period show that K and n are 2464 and 1.621 with the cube root method, and 7154 and 1.791 with the sqare root one, respectively. The data for the first month collected mostly from blasting in the upper hornfels show that K and n are 1668 and 1,492 for the cube root and 1219 and 1,366 for the square root, respectively. Such a significant decrease in the K and n values from the test period through the first month for the weathered and comparatively well crack developed rocks hard and compact lower quartzite, may be due to difference in attenuation of waves propagating through physically different media. Therefore, for more effective safety design and blasting, it seems that it may be n to adopt appropriate K and n values, with getting lower step by step while proceeding the operation. In the meantime, the attenuation rate of K and n together with SD cross point for the cube and square root methods indicates that the cube root one appears to be more applicable than the square root for this area with limited distance(The maximum is 100m).

• Nuclear Engineering and Technology
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• v.26 no.1
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• pp.126-139
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• 1994

Best-estimate thermal-hydraulic codes, CATHARE2 V1.2 and RELAP5/MOD3, hate been assessed against the BETHSY 6.2 tc six-inch cold leg break loss-of-coolant accident (LOCA) test. Main objective is to analyze the overall capabilities of the two codes on physical phenomena of concern during the small break LOCA i.e. two-phase critical flow, depressurization, core water level de-pression, loop seal clearing, liquid holdup, etc. The calculation results show that the too codes predict well both in the occurrences and trends of major two-phase flow phenomena observed. Especially, the CATHARE2 calculations show better agreements with the experimental data. However, the two codes, in common, show some deviations in the predictions of loop seal clearing, collapsed core water level after the loop seal clearing, and accumulator injection behaviors. The discrepancies found from the comprision with the experimental data are larger in the RELAP5 results than in the CATHARE2. To analyze the deviations of the two code predictions in detail, several sensitivity calculations have been performed. In addition to the change of two-phase discharge coefficients for the break junction, fine nodalization and some corrections of the interphase drag term are made. For CATHARE2, the change of interphase drag force improves the mass distribution in the primary side. And the prediction of SG pressure is improved by the modification of boundary conditions. For RELAP5, any single input change doesn't improve the whole result and it is found that the interphase drag model has still large uncertainties.

• Nutrition Research and Practice
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• v.7 no.1
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• pp.43-48
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• 2013

Quantities as well as distributions of adipose tissue (AT) are significantly related to cardiovascular disease (CVD) risk factors and can be altered with caloric restriction. This study investigated which cross-sectional slice location of AT is most strongly correlated with changes in CVD risk factors after caloric restriction in obese Korean women. Thirty-three obese pre-menopausal Korean women ($32.4{\pm}8.5$ yrs, BMI $27.1{\pm}2.3\;kg/m^2$) participated in a 12 weeks caloric restriction program. Subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) were measured using computed tomography (CT) scans at the sites of L2-L3, L3-L4, and L4-L5. Fasting serum levels of glucose, insulin, triglyceride, total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), leptin and homeostasis model assessment-insulin resistance (HOMA-IR) were observed. Pearson's partial correlation coefficients were used to assess the relationship between AT measurement sites and changes in CVD risk factors after calorie restriction. When calories were reduced by 350 kcal/day for 12 weeks, body weight (-2.7%), body fat mass (-8.2%), and waist circumference (-5.8%) all decreased (P < 0.05). In addition, following caloric restriction, serum levels of glucose (-4.6%), TC (-6.2%), LDL-C (-5.3%), leptin (-17.6%) and HOMA-IR (-18.2%) decreased significantly (P < 0.05) as well. Changes in VAT at the level of L3-L4 were significantly greater than those at other abdominal sites, and these changes were correlated with changes in TC (P < 0.05), LDL-C (P < 0.001), SBP (P < 0.001) and HOMA-IR (P < 0.01). These results show that VAT at L3-L4 had a stronger correlation with CVD risk factors than with other AT measurement sites after caloric restriction.

• Journal of Science Education
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• v.41 no.3
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• pp.281-296
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• 2017

The purpose of this study is to explore the science learning motivation of technical high school students through comparison with general high school students. 596 high school students and 1063 general high school students participated in the study. Three statistical methods were used for data analysis: two-way ANOVA, independent sample t-test, and Pearson correlation analysis. The results showed that the interaction between school type and grade had a significant effect on the difference of students' motivation for science learning. There was a significant difference in learning motivation among general high school students according to academic year, while there was no significant difference between first and second grader of technical high school students. Especially, technical high school students showed low level of science learning motivation compared to the students in general high school. The correlations among five motivational factors of science learning motivation were also significantly lower than that of general high school students. Lastly, the result of correlation analysis between science motivation and academic achievement showed that second year students in technical high school had less correlation coefficients than the first year students. Given these results, it is necessary to develop a educational strategy for enhancing science learning motivation of technical school students. We will discuss the direction of science education for technical high school based on our findings.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.2
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• pp.304-314
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• 2020

This cross-sectional descriptive study investigated the influence of romantic relationships' characteristics, self-esteem and sexual autonomy on limerence in dating relationships among female college students who had or were currently engaged in a dating relationship. The data was collected through self-reported structured questionnaires from 167 female Korean college students using convenient sampling methods from November 25, 2012 to December 20, 2012. The data was analyzed using t-tests, one-way analyses of variance, Scheffe's test, Pearson's correlation coefficients, and multiple linear regression analysis with the IBM SPSS 23.0 program. The results showed that a significant difference was found in limerence according to the frequency of experiencing romantic breakup (F=4.16, p=.003), and limerence in dating relationships was negatively correlated with self-esteem (r=-.31, p<.001) and sexual autonomy (r=-.21, p=.006). Self-esteem and the frequency of romantic breakups explained 20% of limerence in dating relationships among the participants (F=8.03, p<.001). Therefore, as a strategy to solve the problems related to limerence during the period of dating, cognitive and educational interventions are needed to strengthen the self-esteem and sexual autonomy of college students who have had a high number of separations. In addition, early screening of college students with risk factors for limerence and providing problem-solving based counseling will help improve their psychological health.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.1
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• pp.355-367
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• 2018

The purpose of this study was to identify the predictors of the quality of life in community dwelling vulnerable older women with chronic joint pain. A cross-sectional study was conducted on 234 participants registered at a visiting health care service in the public health center of C-city. The structured questionnaire were used to collect data on the general characteristics, pain rating index, pain intensity, perceived health status, functional independence, sleep pattern, depression, and quality of life from February 16 to March 13, 2017. The data were analyzed using a t-test, ANOVA, Pearson's correlation coefficients, and hierarchical multiple regression analysis. The significant factors of the quality of life including general characteristics were depression (${\beta}=-.60$, p<.001), pain intensity scale (${\beta}=-.15$, p=.007), health insurance type (${\beta}=.15$, p=.001), perceived health status (${\beta}=.14$, p=.007), duration of pain (${\beta}=-.10$, p=.019), marital status (${\beta}=.10$, p=.024), and functional independence (${\beta}=.09$, p=.036). These factors accounted for 63.1% of the total variance in the quality of life. The findings suggest that a public healthcare program on managing depression is effective in improving the quality of life in community dwelling older women with chronic joint pain. Public health nurses should intervene in nursing care for economically vulnerable aged and pain management based on a precise assessment from the beginning of pain.

• Journal of Pharmaceutical Investigation
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• v.32 no.2
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• pp.119-125
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• 2002

A rapid, selective and reproducible high-performance liquid chromatographic method has been developed for the determination of terazocin in human plasma. Terazocin plus the internal standard, prazocin hydrochloride, were extracted from alkalified plasma with tert-butylmethyl ether, back-extracted into 0.05% phosphoric acid. Fifty ${\mu}l-portions$ of extract were injected onto a octadecylsilane column and eluted with a mixture of acetonitrile, water and triethylamine (30 : 70 : 0.1 v/v, adjusted to pH 5.0 with dilute phosphoric acid) at a flow rate of 1.0 ml/min. The fluorescence intensity of column eluents was monitored at excitation wavelength of 250 nm and emission wavelength of 370 nm. No interference peaks were observed. The practical limit of quantitation was 5 ng/ml for terazocin. The average intraday and interday coefficients of variation were 4.15 and 3.54%, respectively. Also intraday and interday precisions over the range $5{\sim}60\;ng/ml$ were $0.49{\sim}2.92\;and\;0.38{\sim}5.12%$, respectively. The bioequivalence of two terazosin tablets, the $Hytrine^{\circledR}$ (Il Yang Pharmaceutical Co., Ltd.) and the $Teratonin^{\circledR}$ (Sam-A Pharmaceutical Co., Ltd.), was evaluated according to the guideline of Korea Food and Drug Administration (KFDA). Sixteen healthy male volunteers $(24.6{\pm}2.0\;years\;old)$ were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After one tablet containing 2 mg of terazosin was orally administered, blood was taken at predetermined time intervals and the concentration of terazosin in plasma was determined with a HPLC method using spectrofluorometric detector. AUC was calculated by the linear trapezoidal method. $C_{max}\;and\;T_{max}$ were compiled from the plasma drug concentration-time data. Analysis of variance (ANOVA) was utilized for the statistical analysis of the parameters. The results showed that the differences in $AUC_t,\;C_{max}\;and\;T_{max}$ between the two preparations were 0.21 %, 5.53% and 8.82%, respectively. The powers $(1-{\beta})\;for\;AUC_t,\;C_{max}\;and\;T_{max}$ were >99%, 97.49%, and 33.26%, respectively. Minimum detectable differences $({\Delta},\;%)\;at\;{\alpha}=0.1\;and\;1-{\beta}=0.8$ and the 90% confidence intervals were all less than ${\pm}20%$ except for $T_{max}.\;AUC_t\;and\;C_{max}$ met the criteria of KDFA for bioequivalence, indicating that $Teratonin^{circledR}$ tablets are bioequivalent to $Hytrine^{circledR}$ tablets.