• 융합신호처리학회논문지
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• 제1권1호
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• pp.7-14
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• 2000

최근 들어 초고속 정보통신기기 소자와 디지털 신호처리 기술에 힘입어 적응잡음제거 기술이 비약적인 발전을 이룩하게 되었다. 그러나 실제로 적응잡음제거, 에코제거 등의 여러 응용에서 만족할 만한 결과를 얻기 위해서는 수천이 넘는 적응필터계수가 요구된다. 계수의 수가 많은 적응 FIR 필터의 복잡한 계산 량을 줄이고 빠른 수렴을 얻기 위한 시도로 본 연구에서는 주파수영역 적응필터와 다중지연 주파수영역 적응필터 알고리즘을 실시간 처리 관점에서 서로 비교하였다. 긴 탭의 주파수영역 적응필터에서 발생하는 시간지연은 다중지연 주파수영역 적응필터를 적용하여 개선하려다. 또한 일반 적응잡음제거환경과 Cross talk 환경에 주파수영역 적응필터을 적용하여 그 알고리즘의 실시간 처리 가능성을 dSPACE 1103 보드를 통하여 확인하였다

• 여성건강간호학회지
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• 제18권1호
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• pp.49-61
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• 2012

Purpose: The purpose of this study was to examine the experiences of the use of external breast prostheses among breast cancer survivors in Korea. Methods: A qualitative descriptive study was conducted, using focus groups. Data were collected from breast cancer survivors who were patients of C women's hospital in Seoul, Korea. Data were analyzed using content analysis in order to identify significant themes. Results: Participants included forty breast cancer survivors who had mastectomy as a surgical treatment. Four themes emerged from the collected data were: 1) concern over the high price of external breast prosthesis, 2) irregular use of external breast prosthesis, 3) unsatisfied with mastectomy bra, and 4) wanting to hide or not to talk about using breast prosthesis openly. Conclusion: Since most participants reported irregular use and negative experiences related to external breast prosthesis or mastectomy bra use, healthcare workers should allow more time for proper fitting and counseling and consulting with breast cancer survivors. In addition, health care providers as well as family and friends should keep in mind that cancer survivors need support that can help them cope by using positive reframing. Furthermore, improvements in the coverage of costs and services are needed for these women. This would be helpful for breast prosthesis users.

• 한국재료학회:학술대회논문집
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• 한국재료학회 2009년도 추계학술발표대회
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• pp.4.1-4.1
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• 2009

The dream of futurists andtechnologists is to build complex, multifunctional machines so small that theycan only be seen with the aid of a microscope. The unprecedented technologyadvancements in miniaturizing integrated circuits on semiconductors, and theresulting plethora of sophisticated, low cost electronic devices demonstratethe impact that micro/nano scale engineering can have when applied only to thearea of electrical and computer engineering. Emerging research efforts indeveloping organic and inorganic nano materials together with using micro/nanofabrication techniques for implementing integrated multifunctional devices hopeto yield similar revolutions in other engineering fields. By cross linking theindividual engineering fields through micro/nano technology, various organicand inorganic materials and miniaturized system devices can be developed thatwill have future impacts in the IT and life science applications. Yet to buildthe complex micromachines and nanomachine of the future, engineering will needto develop the technology capable of seamlessly integrating these materials andsubsystems together at the micro and nano scales. The micromachines of thefuture will be “integrated nanosystems,” complex devices requiring the integration of multiple materials,phenomena, technologies, and functions at the same platform. To develop thistechnology will require great efforts in materials science and engineering, infundamental and applied sciences. In this talk, we will first discuss thenature of micro and nanotechnology research for IT and life sciences, and thenintroduce selected current activities in micro and nanotechnology research fororganic and inorganic materials and devices. The newly developed micro/nanofabrication processes and devices, combined with in-depth scientificunderstandings of materials, can lead to rapid development of next generationsystems for applications in IT and life sciences.

• 한국전자파학회논문지
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• 제15권11호
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• pp.1034-1042
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• 2004

본 논문에서는 64-QAM 디지털 무선중계 장치에 적용할 목적으로 주파수 선택적 페이딩 책 중의 하나인 아날로그 기울기 등화기의 이론적 모델, 구현 및 성능을 제시하였다. 또한 주파수 선택적 페이딩에 대해 기저대역 의 채널 모델링을 통해 I 및 Q 채 널의 상호간섭을 분석 하였고, 이 를 근거로 IF 대역에서 아날로그 기울기 등화기 구현을 위한 방법을 유도하였다. 페이딩을 받은 채널에 대해 기울기 등화기의 적용 유무에 따라 시간 및 주파수 영역에서 각각 신호의 영향을 살펴보았다. 그리고 무선중계 장치의 성능을 나타내는 시그너쳐(signature)를 통해 비트 오율 $10^{-3}$ 기준으로 신호 대역폭의 가장자리에서 약 6.2 dB 개선됨을 보였다.

• 식물병연구
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• 제23권3호
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• pp.212-227
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• 2017

Pseudomonas chlororaphis O6, isolated from the roots of dryland, field-grown commercial wheat in the USA, enhances plant health and therefore it is used in agriculture as a biofertilizer and biocontrol agent. The metabolites produced by this pseudomonad stimulate plant growth through direct antagonism of pathogens and by inducing systemic resistance in the plant. Studies upon P. chlororaphis O6 identify the pathways through which defined bacterial metabolites generate protection against pathogenic microbes, insects, and nematodes. P. chlororaphis O6 also triggers plant resistance to drought and salinity stresses. The beneficial determinants are produced from bacterial cells as they form biofilms during root colonization. Molecular control these processes in P. chlororaphis O6 involves the global regulatory Gac/Rsm signaling cascade with cross-talk between other global regulatory pathways. The Gac/Rsm regulon allows for coordinate phasing of expression of the genes that encode these beneficial traits among a community of cells. This review provides insights on the Gac/Rsm regulon in expression of beneficial traits of the P. chlororaphis O6 which can contribute to help yield enhancement and quality in agricultural production.

• 한국환경성돌연변이발암원학회지
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• 제23권1호
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• pp.35-40
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• 2003

Polycyclic aromatic hydrocarbons (PAH) are frequently detected in food, water, soil, and sediment and are widespread environmental pollutants formed by the incomplete combustion of fossil fuels, woods and other organic matter. PAHs are considered to be probable human carcinogens. The mechanism of action of PAHs has been studied extensively, however it is not clear how PAHs turn on CYP1A1 in human breast cancer. Our laboratory have been studied the effect of PAHs in the human breast cancer cell MCF7. In this study, we examined the ZR-75-1 human breast cancer cells as a new system to evaluate bioactivity of PAHs. ZR-75-1 human breast cancer cell line responses to estrogen and progesteron. We have been able to estbilish long term culture system of this cells then used for the study to observe the effect of PAHs. We demonstrate that PAHs induced the CYP1A1 promoter and 7-ethoxyresolufin O-deethylase (EROD) activity in a concentration-dependant manner. RT-PCR analysis indicated that PAHs significantly up-regulate the level of CYP1A1 mRNA. Some of PAHs showed stronger stimulatory effect on CYP1 gene expression than TCDD. Apparently, ZR-75-1 cells have Aryl hydrocarbon receptors, therefore it would be good experimental tool to study the cross-talk between PAHs and steroid actions.

• Nutritional Sciences
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• 제6권1호
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• pp.12-19
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• 2003

The measurement of the total antioxidant capacity (TAC) of human plasma has been widely applied in nutritional science, for example to evaluate the antioxidant contribution of dietary components and to study, although indirectly, the bioavailability of dietary antioxidants. Several methods have been proposed for the measurement of TAC, most of them based on the ability of plasma to withstand the oxidative damage induced by aqueous radicals. Although plasma contains both hydrophilic and lipophilic antioxidants that interact through extensive cross-talk in most of the methods employed for the TAC measurement, the hydrophilic antioxidants such as ascorbic acid, uric acid, and protein thiols mainly contribute to the total antioxidant plasma capacity (almost 70%) while lipophilic antioxidants embedded in the lipoproteins (carotenoids, a-tocopherol, ubiquino1-10) participate only in a negligible amount (less than 5%). The present paper reviews the analytical methods used to assess the TAC and in particular focuses on new approaches that are capable of distinguishing the antioxidant capacity of both the aqueous and lipid compartments of plasma. The general principle of the method as well as some in vitro and ex vivo applications will be discussed within the text.

• Biomolecules & Therapeutics
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• 제25권1호
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• pp.44-56
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• 2017

Insulin resistance is characterized by the reduced ability of insulin to stimulate tissue uptake and disposal of glucose including cardiac muscle. These conditions accelerate the progression of heart failure and increase cardiovascular morbidity and mortality in patients with cardiovascular diseases. It is noteworthy that some conditions of insulin resistance are characterized by up-regulation of the sympathetic nervous system, resulting in enhanced stimulation of ${\beta}$-adrenergic receptor (${\beta}$AR). Overstimulation of ${\beta}$ARs leads to the development of heart failure and is associated with the pathogenesis of insulin resistance in the heart. However, pathological consequences of the cross-talk between the ${\beta}$AR and the insulin sensitivity and the mechanism by which ${\beta}$AR overstimulation promotes insulin resistance remain unclear. This review article examines the hypothesis that ${\beta}$ARs overstimulation leads to induction of insulin resistance in the heart.

• 한국소음진동공학회논문집
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• 제14권12호
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• pp.1279-1286
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• 2004

This paper continues companion paper, part I : measurement and analysis. As shown in companion Paper, information and energy in monaural signal is quite different from that of binaural signal. In this paper, difference between monaural and binaural signal of transportation noise are investigated in subjective response test. We executed hearing screening test before giving a subject response test and excluded subjects who had physical hearing loss. An annoyance response test was conducted using headphone to avoid cross-talk effect in binaural testing. Percentage of highly annoyed under binaural signal reproduction is higher than percentage of highly annoyed under monaural signal reproduction. Result implies binaural reproduction technique is proper for a study of human response to short-term noise exposure in a headphone simulated-environment.

• Asian Pacific Journal of Cancer Prevention
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• 제15권16호
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• pp.6485-6488
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• 2014

Research over the years has progressively and sequentially provided near complete resolution of regulators of the DNA repair pathways which are so important for cancer prevention. Ataxia-telangiectasia mutated kinase (ATM), a high-molecular-weight PI3K-family kinase has emerged as a master regulator of DNA damage signaling and extensive cross-talk between ATM and downstream proteins forms an interlaced signaling network. There is rapidly growing scientific evidence emphasizing newly emerging paradigms in ATM biology. In this review, we provide latest information regarding how oxidative stress induced activation of ATM can be utilized as a therapeutic target in different cancer cell lines and in xenografted mice. Moreover, crosstalk between autophagy and ATM is also discussed with focus on how autophagy inhibition induces apoptosis in cancer cells.