• Korean Journal of Veterinary Service
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• v.39 no.1
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• pp.41-49
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• 2016

In the present study, fast and robust methods for the next generation sequencing (NGS) were developed for analysis of PRRSV full genome sequences, which is a positive sensed RNA virus with a high degree of genetic variability among isolates. Two strains of PRRSVs (VR2332 and VR2332-R) which have been maintained in our laboratory were used to validate our methods and to compare with the sequence registered in GenBank (GenBank accession no. EF536003). The results suggested that both of strains had 100% coverage with the reference; the VR2332 had the coverage depth from minimum 3 to maximum 23,012, for the VR2332-R from minimum 3 to maximum 41,348, and 22,712 as an average depth. Genomic data produced from the massive sequencing capacities of the NGS have enabled the study of PRRSV at an unprecedented rate and details. Unlike conventional sequence methods which require the knowledge of conserved regions, the NGS allows de novo assembly of the full viral genomes. Therefore, our results suggested that these methods using the NGS massively facilitate the generation of more full genome PRRSV sequences locally as well as nationally in regard of saving time and cost.

• Journal of Positioning, Navigation, and Timing
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• v.6 no.4
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• pp.211-221
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• 2017

Ellipsodially referenced survey (ERS) is considered as one of the challenging issues in the hydrographic surveys due to the fact that the bathymetric data collected by this technique can be readily transformed either to the geodetic or the chart datum by application of some geoscientific models. Global Navigation Satellite Systems (GNSS) is a preferred technique to determine the ellipsoidal height of a vessel reference point (RP) because it provides cost-effective and unprecedentedly accurate positioning solutions. Especially, the GNSS-derived heights include heave and dynamic draft of a vessel, so as for the reduced bathymetric solutions to be potentially free from these corrections. Although over the last few decades, differential GNSS (DGNSS) has been widely adopted in the bathymetric surveys, it only provides limited accuracy of the vertical component. This technical barrier can be effectively overcome by adopting the so-called GNSS carrier phase (CPH) based techniques, enhancing accuracy of the height solution up to few centimeters. From the positioning algorithm standpoint, the CPH-based techniques are categorized under absolute and relative positioning in post-processing mode; the former is precise point positioning (PPP) correcting errors by the global or regional models, the latter is post-processed kinematic positioning (PPK) that uses the differencing technique to common error sources between two receivers. This study has focused on assessment of achievable accuracy of the ellipsoidal heights obtained from these CPH-based techniques with a view to their applications to hydrographic surveys where project area is, especially, few tens to hundreds kilometers away from the shore. Some field trials have been designed and performed so as to collect GNSS observables on static and kinematic mode. In this paper, details of these tests and processed results are presented and discussed.

• Korean Journal of Occupational Health Nursing
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• v.11 no.1
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• pp.44-51
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• 2002

Purpose: Surgical Site Infection(SSI) is the third most common cause of nosocomial infection, so that it results in serious socioeconomic impact such as extra hospitalization, mortality and health care cost. The aim of this study was to analyses the SSI that based on the degree of wound contamination and patient risk index after general surgery and to generate a reference data for the effective management and reducing SSI. Method: From July, 1999 to June, 2000, 1080 cases which presented with surgical site infection after general surgery at S hospital in chunchon city were included in this study. The data were collected by review of the medical records retrospectively. The collected data, in accordance with the test purpose, is analyzed by SPSS/PC+ program, using real numbers, percentage, $X^2$ test, Pearson's correlation and stepwise logistic regression. Result: The overall wound infection rate was 4.7%(51 cases out of 1,080). The infection rate of clean wounds was 1.4%. Surgical site infection rate for patient risk index scores of 0, 1, 2 and 3 was 1.9%, 8.0%, 13.1% and 20.0%, respectively and increased significantly according to patient risk index(p=.000). Sixteen of the fifty one(31.4%) surgical site infections were found during an outpatient visit after discharge. Multivariate analysis, identified two independent variables : duration of postoperation stay(p=.000), age(p=.037). The most frequent isolated organisms were Pseudomonas aeruginosa(21%) and Staphylococcus aureus(21%). Also Staphylococcus aureus were all MRSA(Methicillin Resistant S. aureus). Conclusion: In this study, SSI was analysed according to the degree of wound contamination and patient risk index after general surgery. The data that obtained from this study is expected that it would be available for surveillance and control of SSI.

• KIEAE Journal
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• v.14 no.2
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• pp.77-86
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• 2014

Plenty of efforts have been made in the traditional architecture of Korea, Hanok, to develop various elements such as restoration, the introduction of new design, and energy-saving while systemic setups on standard and evaluation of eco-friendly energy design of Hanok are lacking. If we evaluate energy performance based on current standards without reflecting unique features of Hanok on the system, Hanok will be included in the very low grade among the residential buildings being included in the approval system of eco-friendly architecture or the unique features will be modified and the burden of increased construction cost. Therefore, this study is to prepare the basic reference for the introductory evaluation system by evaluating the energy performance level of NEO-Hanok based on the current building energy rating system. The result for NEO-Hanok based on the building energy rating system, we propose the rating standard with scorecard elements of NEO-Hanok by considering the necessity of identity and standard for NEO-Hanok. As a result of infiltration test to check the tightness, it was measured as 10.81 times/h (50 ACH). As we switch from the main insulation for the wall from the glass wool 64k(0.035W/mk) to rigid polyurethane foam first class first unit (0.024W/mk), the result was slightly increased from the first demand quantity rating yield $249.8kWh/m^2{\cdot}yr$ to $235.0kWh/m^2{\cdot}yr$. Current certificate system is focused more on the heating load than the cooling load, it is disadvantageous for Hanok, which has less cooling energy consumption in summer. The rating result from the target building study is level 4.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.51 no.4
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• pp.210-220
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• 2002

We analysised the effect of harmonics on electric machines of substation power system barred on quantitatively measured harmonics and proposed the methods for prevention of harmonics through checking on transformer, rectifier and cable's capacities against harmonics with reference to KEPCO's electricity service standard. In order to analysis harmoninics of silicon rectifier that is power source in DC substation, computer simulations for a substation with TR of high voltage distribution switchboard are performed. Simulation results show that the total harmonic distortion factor becomes smaller for TR primary and receiving points in order rather than silicon rectifier which is harmonic generation source so that the harmonics generated frets each rectifier are outflowed to power supply and high voltage distribution switchboard The result of higher distortion factors of voltage and current for rectifier with 100% load than those with 50 % and 30% indicates that the waveform of voltage and current for the real substation power system at the office-going and the closing hours with heavy loads might be more distorted. As proposed methods for harmonic reduction, the conventional 6 pulse-type for substation is required to be replaced by 12 pulse-type for reduction of 5th and 7th harmonics. The active filter rather than the passive filter is more effective due to severe variance of rectifier loads, but the high cost is price to be paid. In view of installation area and costs, the use of 12 pulse-type transformer is desirable and then the parallel transformer and the rectifier within the substation must be replaced at the same time. Other substations with parallel feeder can use 6 pulse-type transformer.

• Smart Structures and Systems
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• v.26 no.1
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• pp.89-102
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• 2020

Shape memory alloy (SMA)-based Superelasticity-assisted Slider (SSS) is proposed as an engineering solution to practically exploit the well-accepted advantages of both sliding isolation and SMA-based recentering. Self-centering capability in SSS is provided by austenitic SMA cables (or wire ropes), recently attracting a lot of interest and attention in earthquake engineering and seismic isolation. The cables are arranged in various novel and conventional configurations to make SSS versatile for aseismic design and retrofit of structures. All the configurations are detailed with thorough technical drawings. It is shown that SSS is applicable without the need for Isolation Units (IUs). IUs, at the same time, are devised for industrialized applications. The proof-of-concept study is carried out through the examination of mechanical behavior in all the alternative configurations. Force-displacement relations are determined. Isolation capabilities are predicted based on the decreases in seismic demands, estimated by the increases in effective periods and equivalent damping ratios. Restoring forces normalized relative to resisting forces are assessed as the criteria for self-centering capabilities. Lengths of SMA cables required in each configuration are calculated to assess the cost and practicality. Practical implementation is realized by setting up a small-scale IU. The effectiveness of SSS under seismic actions is evaluated using an innovative computer model and compared to those of well-known Isolation Systems (ISs) protecting a reference building. Comparisons show that SSS seems to be an effective IS and suitable for earthquake protection of both structural and non-structural elements. Further research aimed at additional validation of the system are outlined.

• Architectural research
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• v.16 no.4
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• pp.157-166
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• 2014

This research investigates the design process of free-form architecture to understand the design strategy and changing factors during the development phase and the cause for them. It is aimed to foresee the changing factors from the design process and to reduce design changes. It analyzes the design changes of free-form architecture based on projects with finalized documentation or under construction in South Korea. Many free-form shapes of the free-form architectures have to be adjusted to rigid-form in order to satisfy function and be economical to build. The research finds three patterns in design changes. First, from the factors for design changes: function, constructability, design, program add/subtract, efficiency, circulation; Function and Constructability are the higher factors compared with the rest. The two are the design changes suitable for actual usage and cost savings. Second, each project has different predominant factors for design changes as the degree of free-form is different. Contrary to initial expectation, the greater the degrees of free-form of the competition scheme, the higher the rate of Function among the factors for design changes. Constructability is higher when the degree of the free-form is less than others. It means that the lower the degree of the free-form, the more properly planned the space of the building is. Last, Constructability of free-form architecture is considered during the earlier design phase than definite-form, one by which the design changes by comparing 'Before fixed Space Program' (BSP) and 'After fixed Space Program' (ASP) design changes. The research would be helpful as a reference for setting up competition guidelines to reduce trial and error during the design process.

• Journal of the Korea Society of Computer and Information
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• v.8 no.4
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• pp.75-80
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• 2003

In this paper, we designed add current scan system basically. Although NDT system using AC method in now days had problem with limit of detection rate and limit of device organization, in this paper, we made up these problem so that designed device smaller than system used, reduction of cost of system organization and precision of measuring crack. Also, AC leakage flux system had high accuracy about minute crack in the surface and advantage of designing system easily so that we designed system for concerning about crack of surface. Furthermore, it can be able to detect exact crack of reference in wide area by using DSP320C31 chip to reduce the time of measuring crack.

• Design & Manufacturing
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• v.10 no.3
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• pp.14-19
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• 2016

Thermally or electrically conductive filler reinforced polymer composites are extensively being developed as the demand for light weight material increases rapidly in industiral applications need good conductivity such as heat sink of the electronics or light. Carbon or ceramic materials like graphite, carbon nanotube or boron nitride are typical conductive fillers with good thermal or electical conductivity. Using these conductive fillers, the polymer composites in the market show wide range of thermal conductivity from approximately 1 W/mK to 20 W/mK, which is quite enhanced considering the thermal conductivity lower than 0.5 W/mK for most polymeric materials. The practical use of these composites, however, is yet limited to specific applications because most composites are still not conductive enough or too difficult to process, too brittle, too expensive for higher conductivity. For practical use of conductive composite, the thermal conductivity required depending on the heat releasing mode are studied first for simplified unit cooling geometry to propose thermal conductivities of the composites for reasonable cooling performance comparing with the metal heat sink as a reference. Also, as a practical design for heat sink based on polymer composite, composite and metal sheet hybrid structures are investigated for LED lamp heat sink and audio amplication module housing to find that this hybrid structure can be a good solution considering all of the cooling performance, manufacturing, mechanical performance, cost and weight.

• Health Policy and Management
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• v.19 no.4
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• pp.98-120
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• 2009

The purpose of this study is to elicit preference for drug listing decision criteria and to estimate the ICER threshold in South Korea using the discrete choice experiment (DCE) method. To collect the data, a DCE survey was administered to a subject sample either educated in the principle concepts of pharmacoeconomics or were decision makers within that field. Subjects chose between alternative drug profiles differing in four attributes: ICER, uncertainty, budget impact and severity of disease. The orthogonal and balanced designs were determined through computer algorithm to take the optimal set of drug profiles. The survey employed 15 hypothetical choice sets. A random effect probit model was used to analyze the relative importance of attributes and the probabilities of a recommendation response. Parameter estimates from the models indicated that three attributes (ICER, Impact, Severity of disease) influenced respondents' choice significantly(p${\pm}$0.001). In addition, each parameter displayed an expected sign. The Lower the ICER, the higher the probability of choosing that alternative. Respondents also preferred low levels of uncertainty and smaller impact on health service budget. They were also more likely to choose drugs for serious diseases rather than mild or moderate ones. Uncertainty however is not statistically significant. The ICER threshold, at which the probability of a recommendation was 0.5, was 29,000,000 KW/QALY in expert group and 46,500,000 KW/QALY in industry group. We also found that those in our sample were willing to accept high ICER to get medication for severe diseases. This study demonstrates that the cost-effectiveness, budget impact and severity of disease are the main reimbursement decision criteria in South Korea, and that DCE can be a useful tool in analyzing the decision making process where a variety of factors are considered and prioritized.