• Title/Summary/Keyword: Correlated Flow

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Interictal rCBF SPECT, MRI and Surgical Outcome of Intractable Temporal Lobe Epilepsy (난치성 측두엽간질의 발작간 뇌혈류 SPECT, MRI와 수술성과 비교)

  • Zeon, Seok-Kil;Joo, Yang-Goo;Lee, Sang-Doe;Son, Eun-Ik;Lee, Young-Hwan
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.3
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    • pp.307-312
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    • 1994
  • Interictal single photon emission computed tomography of regional cerebral blood flow (rCBF SPECT) in 18 intractable temporal lobe epilepsy patients(8 male and 10 female patients: average 23.5 years old) were compared with 2.0 T magnetic resonance imaging (MRI). And surgical outcome was analysed with the findings, symptom duration and lateralization of temporal lobe. Preoperatively rCBF SPECT was done in all 18 patients with intravenous injection of 740 MBq 99mTc-HMPAO. MRI was also done preoperatively in 13 patients. Surgical outcome was classified by Engel's outcome classification(four-part classification recommended at the first Palm Desert conference). rCBF SPECT detected correctly lateralising abnormality of temporal lobe hypoperfusion in 13/18(72.2%), contralateral temporal lobe hypoperfusion in 2/18(11.1%) and showed no def-inite abnormality in 3/18(16.7%). The positive predictive value of unilateral temporal lobe hypoperfusion was 87%. MRI detected correct localising abnormality in 8/13(61.5%), such as hippocampal atrophy(7/13), asymmetric temporal horn(6/13), anterior temporal lobe atrophy(1/13), increased signal intensity from hippocampus(1/13) and calcific density(1/13), and no abnormal finding was noted in 5/13(38.5%). There was no false positive findings and the positive predictive value of MRI was 100%. Only 2 cases showed same lateralization findings in rCBF SPECT and MRI. There was no significant correlation between symptom duration and no abnormal findings on SPECT or MRI. Surgical outcome showed class I in 15/18(83.3%), and class II in 2/18(11.1%). One case of no abnormal finding in both SPECT and MRI showed class III surgical outcome. No class IV surgical outcome was noted. Surgical outcome, lateralization of epileptic focus in temporal lobe and abnormal findings in rCBR SPECT or MRI were not significantly correlated.

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Determination of Brain Death by $^{99m}Tc$ DTPA and $^{99m}Tc$ HMPAO Images ($^{99m}Tc$ DTPA와 $^{99m}Tc$ HMPAO를 이용한 뇌사결정)

  • Kim, Jong-Kyu;Sohn, Hyung-Sun;Kim, Sung-Hoon;Yang, Woo-Jin;Lee, Sung-Yong;Chung, Soo-Kyo;Park, Seog-Hee;Kim, Choon-Yul;Bahk, Yong-Whee;Shinn, Kyung-Sub
    • The Korean Journal of Nuclear Medicine
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    • v.29 no.1
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    • pp.15-21
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    • 1995
  • To evaluate availability of cerebral radionuclide imaging for diagnosis of brain death, we examined 25 patients with a suspected clinical diagnosis of brain death. 8 patients were studied by $^{99m}Tc$ DTPA and 15 patients were studied by $^{99m}Tc$ HMPAO (Hexamethyl propyleneamine oxime). Seven patients with $^{99m}Tc$ DTPA studies revealed absence of cerebral blood flow and sagittal sinus activity. All of 15 patients with $^{99m}Tc$ HMPAO studies revealed complete absence of cerebral perfusion. The results of the cerebral radionuclide studies of brain death correlated with other clinical conditions, such as intracranial pressure(ICP), EEG, transcranial doppler sonography(TCDS), and neurologic examination. The ICP of 8 patients, who are confirmed by brain death with $^{99m}Tc$ HMPAO study are elevated in all cases. In conclusion, cerebral radionuclide imaging for diagnosis of brain death is available. $^{99m}Tc$ HMPAO imaging is unequivocal, easily interpreted, well reflect the physiologic state of increased ICP, and provides adequate assessment of posterior fossa activity. In addition, the SPECT imaging with $^{99m}Tc$ HMPAO produces more accurate results due to it's superiority of image contrast and proper localization of radiopharmaceutical distribution than conventional planar imaging.

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Characteristics of Accumulated Soil Carbon and Soil Respiration on Vegetation in Namhangang Basin (남한강 수변역식생의 토양탄소축적량과 토양호흡 특성)

  • Jung, Jisun;Yi, Joonseok;Lee, Jaeho;Shim, Kyomoon;Lee, Jaeseok
    • Korean Journal of Environmental Biology
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    • v.32 no.4
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    • pp.363-370
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    • 2014
  • Various ecosystem carry out fundamental function of material circulation and energy flow through interrelationship with many environmental factors. Therefore, it is crucial to scientifically understand the value of nature to deduce correlation between environmental factor and change of ecosystem function. In this study, we determined the accumulated ecosystem carbon and characteristics of soil respiration on grassland vegetation in Namahangang basin in Namhangang Basin. It was found that the rate of soil respiration was highly correlated with the soil temperature in all communities. The measured soil respiration rates were $1,539mgCO_2\;m^{-2}h^{-1}$, $1,200mgCO_2\;m^{-2}h^{-1}$, $1,215mgCO_2\;m^{-2}h^{-1}$ in Miscanthus sacchariflorus, Phragmites japonica, Salix koreensis communities, respectively. Also, carbon quantities accumulated in litter and soil layers were $40.6tCha^{-1}$ (1.9+38.7), $46.9tCha^{-1}$ (43.0+3.9), $31.2tCha^{-1}$ (28.9+2.3) in M. sacchariflorus, P. japonica, S. koreensis communities, respectively.

Growth Characteristics of Blue-green Algae (Anabaena spiroides) Causing Tastes and Odors in the North-Han River, Korea (북한강 수계에서 이취미를 유발하는 남조류(Anabaena spiroides)의 증식 특성)

  • You, Kyung-A;Byeon, Myeong-Seop;Youn, Seok-Jea;Hwang, Soon-Jin;Rhew, Doug-Hee
    • Korean Journal of Ecology and Environment
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    • v.46 no.1
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    • pp.135-144
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    • 2013
  • Blue-green algae blooms occurred during early winter in the North-Han River, Korea. Among blue-green algae, Anabaena spiroides were observed for approximately 33 consecutive days, between 28 November and 30 December, 2011. A. spiroides emerged from Lake Uiam to Lake Paldang, depending on the flow of the river has spread downstream. Changes of physical water environment like rising water temperature and increasing hydraulic retention time influenced the A. spiroides bloom. The A. spiroides bloom showed a very rapid increase in cell density, and a slow decrease: the cell density increased to a maximum of $11,325cells\;mL^{-1}$ in Lake Paldang (st. 5), and was completely disappeared after the water temperature dropped below $4^{\circ}C$. A decrease in water temperature was the most influential factor among all environmental parameters, for the reduction of A. spiroides cell density. The A. spiroides bloom was accompanied with the occurrence of very high concentrations of the odor metabolite geosmin. Geosmin reached the peak value of $1,640ng\;L^{-1}$ in Lake Paldang (st. 4). The geosmin concentration was very strongly correlated with cell numbers of A. spiroides.

Relationship between fish assemblages community and Streamline complexity (어류군집 특성과 하안형태복잡도와의 관계)

  • Kim, Jin-Ah;Lee, Sang-Woo;Hwang, Gil-Son;Kim, Chulgoo
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.15 no.2
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    • pp.19-29
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    • 2012
  • Numerous studies suggested that fish assemblage structure reflects the status of stream ecosystems. The status of streams integrity, including various trophic levels, water quality and habitat degradation, can be assessed by fish assemblages. In this study, we investigated the relationships between fish assemblages and streamline geometry of streams. Previous studies suggested that geomorphologic parameter can be a critical factor of permeability between adjacent two systems. From a landscape ecological perspective, edges may partially control the flow rate of energy between two adjacent systems. Thus, the Streamline geometry can be a geomorphologic parameter that exhibits the integrity of stream. We selected the Nakdong river for study areas, which is one of major rivers and the longest (525 km) River in South Korea. We used the revised IBI representing overall ecological characteristics of Korean fish assemblages and eight sub-assessment criteria of IBI, collected from 82 sampling sites in the Nakdong River. For calculating the Streamline geometry, we measured fractal dimension index that generally used in biology, ecology and landscape ecology. We used the digital land-use/land-cover map and generated a 1-km buffer for each sampling site and refined the shape of the Streamlines. Pearson correlation analyses were performed between Streamline geometry and IBI and sub-assessment criteria of IBI. The results show that IBI and eight sub-assessments of fish are significantly correlated with geometry of Streamline. The fractal dimension of Streamline geometry were related with IBI (r = 0.48) and six sub-assessments of IBI, including total number of native fish and native species, the number of riffle benthic species, sensitive species, tolerant species and native insectivore. Especially, the number of tolerant species(r = -0.52) and native insectivore(r = 0.52) show strong correlation with geometry of Streamline. These results indicate that lower Streamline geometry can result in poor fish assemblages, while higher geometry of Streamline can enhance fish assemblages by potentially supplying insects and better habitat conditions. We expect the results of our study to be useful for stream restoration and management. However, we see the necessity of study investigating the mechanisms how Streamline geometry affect fish assemblages.

Relations of Nutrient Concentrations on the Seasonality of Algal Community in the Nakdong River, Korea (낙동강 조류군집의 계절적 변화와 영양염 농도와의 관계)

  • Yu, Jae Jeong;Lee, Keung Lak;Lee, Hye Jin;Hwang, Jeong Wha;Lyu, Heuy Seong;Shin, La Young;Park, A Reum;Chen, Se Uk
    • Journal of Korean Society on Water Environment
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    • v.31 no.2
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    • pp.110-119
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    • 2015
  • The construction of the eight large weirs in the Nakdong River, the second largest river in Korea, caused big changes in the physical environment of the water system. Algal communities and their correlations with environmental factors, mainly nutrients were studied at five weir areas in the Nakdong River from 2010 to 2013. Water quality, hydrodynamics and algal composition were investigated. Results showed that flow velocities were reduced compared with that before weir construction near the areas where are located in the mid and upstreams of the Nakdong River. A seasonal algal community succession was observed and it was mainly correlated with temperature and phosphorus. Diatoms were dominated from winter to spring months and massive diatomic blooms of Stephanodiscus sp. occurred early in March during survey period. Cyanobacterial blooms of Microcystis sp. occurred from July to September 2013 and was preceded by the lower total phosphorus concentration of $0.05mg\;L^{-1}$. The correlations between total phosphorus concentrations and algal abundances were not significant during the survey periods. However, significant correlation with cyanobacteria was found in the period of weir construction after only at the GG survey site and blooms periods of 7 times in the survey sites, and its correlation coefficients were 0.53 (p<0.001) and 0.42 (p<0.01) respectively. When algal bloom was observed, partially low nutrient concentration was observed in the Nakdong River. In conclusion, partially low nutrient concentration which may result from algal bloom was observed, and we presume it caused the reduction of algal abundunces.

Apoptotic Cell Death of Human Leukemia U937 Cells by Essential Oil purified from Schisandrae Semen (오미자 종자 정유에 의한 인체백혈병 U937 세포의 apoptosis 유도)

  • Choi, Yung Hyun
    • Journal of Life Science
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    • v.25 no.2
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    • pp.249-255
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    • 2015
  • Schisandrae fructus [Schizandra chinensis (Turcz.) Baillon] is a medicinal herb widely used for treating various inflammatory and immune diseases in East Asian countries. The Schisandrae Semen essential oil (SSeo) from this plant has pharmacological activities, including antioxidant, antimicrobial, and antitumoral activities. Nevertheless, the biological activities and underlying molecular mechanisms of the potential anti-cancer effects of this oil remain unclear. In the present study, we investigated the potential inhibition of apoptosis signaling pathways by SSeo in human leukemia U937 cells and evaluated the underlying molecular mechanism. Exposure to SSeo resulted in a concentration-dependent growth inhibition due to apoptosis, which was verified by DNA fragmentation, the presence of apoptotic bodies, and an increase in the sub-G1 ratio. Induction of apoptotic cell death by SSeo was correlated with the down-regulation of members of the inhibitor of apoptosis protein (IAP) family (including X-linked inhibitor of apoptosis protein (XIAP), cIAP-1, and surviving) and anti-apoptotic Bcl-2, and with up-regulation of death receptor (DR) 4 and DR5, depending on dosage. SSeo treatment also induced Bid truncation, mitochondrial dysfunction, proteolytic activation of caspase-3, -8 and -9, and concomitant degradation of activated caspase-3 target proteins such as poly (ADP-ribose) polymerase. Taken together, these findings suggest that SSeo may be a potential chemotherapeutic agent for use in the control of human leukemia cells. Further studies are needed to identify its active compounds.

Observational Characteristics of East Asian Monsoon during the Summers of 1993 and 1994 (1993, 1994년 여름철 동아시아몬순의 관측 특성)

  • Kim, Baek-Jo;Ryu, Chan-Su
    • Journal of the Korean earth science society
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    • v.23 no.4
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    • pp.369-379
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    • 2002
  • The characteristics of the East Asian summer monsoon circulation associated with the cool and wet summer of 1993 and the warm and dry summer of 1994 are investigated by analyzing the atmospheric circulations features in the upper and lower troposphere and by examining the global SST and associated tropical convective precipitation fields. The negative geopotential height anomalies at 500 hPa and 200 hPa in 1993 over East Asia, the central North Pacific, and the western United States were replaced by positive ones in 1994. In addition, the 200 hPa zonal wind anomaly averaged over the East Asian summer monsoon region is negatively correlated with the Korean summer temperature anomaly. The subtropical jet stream in 1993 was displaced into the central part of Korea well south of its normal position. The western Pacific subtropical high was shifted southward, and the East Asian summer rainfall and temperature was above-normal and below-normal, respectively due to the southwestward extension of a cold and dry polar airmass from the Sea of Okhotsk to the Est Sea. In contrast, the subtropical jet stream in 1994 was displaced well north of its normal position. The abrupt northward shift of the western Pacific subtropical high was accompanied with the rapid northward movement of the rain band of the East Asian summer monsoon rainfall. The anomaly patterns of the East Asia summer rainfall and temperature were opposite to those of 1993. Large sea surface temperature anomalies of opposite signs existed in the tropical Pacific with a mature El $Ni{\~{n}o$ in 1993 and a weak La $Ni{\~{n}a$ condition in 1994. The role of the anomalous convective precipitation in the western Pacific and the Indian Ocean related with the variations in the low-level cross-equatorial flow along the northwestern periphery of the Australian high and the Mascarene high is probably to influence a large-scale atmospheric circulation over the East Asia during both the years.

Analysis of Characteristics of Landslide Susceptibility in Rugged Mountain Range in the Korean National Park (산악형 국립공원지역의 산사태 발생과 취약지역 특성 분석)

  • Lee, Sung-Jae;Lee, Eun-Jai;Ma, Ho-Seop
    • Journal of Korean Society of Forest Science
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    • v.108 no.4
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    • pp.552-561
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    • 2019
  • In korea, debris-flow disasters are induced by typhoon and localized torrential rainfall annually. These disasters are particularly severe in the Korean national park due to its geomorphological characteristics. This study was conducted to analyze the landslide characteristics and forest environmental factors of landslide areas located in rugged mountain range in the Korean national park (Mt. Seorak, Mt. Jiri, and Mt. Sobaek). Overall, landslides occurred at 474 sites. The average area of the landslide scar among these sites was 1,212 ㎡. The average landslide sediment was 1,389 ㎥, average landslide length was 75 m, and the average width was 12.9 m. The landslides frequently occurred in regions with igneous rock and coniferous forest. In addition, slope gradient degree (31°-40°), slope gradient direction (N), vertical slope (concave), cross slope (concave), altitude (401-800 m), position (middle), stream order (first order), forest type (mixed), parent rock (igneous), and soil depth (<46 cm). The relationship between landslide soil volume and environmental factors showed positive correlation. The variables of vertical slope (complex), altitude (<1,201 m), and soil depth (<46 cm) correlated significantly at 1 % level.

A Study on Relationship Between Violation of Environmental Regulations and Firm's Characteristics (기업특성과 환경규제 위반의 관계 연구)

  • Kim, In-Su
    • Management & Information Systems Review
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    • v.31 no.4
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    • pp.33-56
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    • 2012
  • The purposes of this paper are analysed the relationship between environmental regulation and financial performance in Korea. The financial performance of listed companies and Outside Auditing firms was evaluated by logistic regression. First, R&D investment is proportionally correlated with the ability to comply with environmental regulations. It can be explained increase of investment in R&D causes enhancement of compliance of environmental regulations with development of environmental technology. Second, statistical significance is not observed between financial aspects such as current ratio, debt-to-equity ratio, cash flow, and operating profit margin and the ability to comply with environmental regulations. It indicates high financial performance could not directly lead investment for the ability of that. Third, in terms of structural aspects, firm size and employees have a reliable correlation with compliance with environmental regulations due to high attention of larger firms for PR, and IR, while capital intensity and gravity, and exports do not. Finally, violation of environmental regulations is not affect by the controlling shareholder ownership.

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