• Title/Summary/Keyword: Coronavirus-19

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COVID-19 Death and BCG Vaccination Programs Worldwide

  • Jirjees, Feras J.;Bashi, Yahya H. Dallal;Al-Obaidi, Hala J.
    • Tuberculosis and Respiratory Diseases
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    • v.84 no.1
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    • pp.13-21
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    • 2021
  • Several clinical trials are being conducted worldwide to investigate the protective effect of the bacillus Calmette-Guérin (BCG) vaccine against death in healthcare providers who are working directly with coronavirus disease 2019 (COVID-19) patients. Clinical studies suggested that certain live vaccines, particularly the BCG vaccine, could reduce the mortality due to other diseases caused by non-targeted pathogens, most probably through the nonspecific effects (heterologous effects). By the end of May 2020, the available information on the COVID-19 pandemic indicated the great effect of the BCG vaccine in reducing the number of COVID-19 death cases. The occurrence of death due to COVID-19 was found to be 21-fold lower in countries with a national BCG vaccination policy than in countries without such a policy, based on the medians of COVID-19 death case per 1 million of the population in these two groups of countries (p<0.001, Mann-Whitney test). Therefore, it can be concluded that the early establishment of a BCG vaccination policy in any country is a key element in reducing the number of COVID-19 and tuberculosis death cases.

A Study and Analysis of COVID-19 Diagnosis and Approach of Deep Learning

  • R, Mangai Begum
    • International Journal of Computer Science & Network Security
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    • v.22 no.9
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    • pp.149-158
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    • 2022
  • The pandemic of Covid-19 (Coronavirus Disease 19) has devastated the world, affected millions of people, and disrupted the world economy. The cause of the Covid19 epidemic has been identified as a new variant known as Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV2). It motives irritation of a small air sac referred to as the alveoli. The alveoli make up most of the tissue in the lungs and fill the sac with mucus. Most human beings with Covid19 usually do no longer improve pneumonia. However, chest x-rays of seriously unwell sufferers can be a useful device for medical doctors in diagnosing Covid19-both CT and X-ray exhibit usual patterns of frosted glass (GGO) and consolidation. The introduction of deep getting to know and brand new imaging helps radiologists and medical practitioners discover these unnatural patterns and pick out Covid19-infected chest x-rays. This venture makes use of a new deep studying structure proposed to diagnose Covid19 by the use of chest X-rays. The suggested model in this work aims to predict and forecast the patients at risk and identify the primary COVID-19 risk variables

Chest CT Imaging Features of the Pulmonary Sequelae in Four Patients with COVID-19 (COVID-19 환자의 네 증례에서 폐 후유증에 대한 흉부 CT 소견)

  • Tae-Eun Kim;Su Young Kim;Byung Hoon Lee
    • Journal of the Korean Society of Radiology
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    • v.83 no.2
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    • pp.378-386
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    • 2022
  • With the ongoing coronavirus disease 2019 (COVID-19) pandemic, there is an increasing interest in the sequelae and care in recovered patients. Although the long-term sequelae of COVID-19 are still unknown, recently published reports suggest that some of the patients have persistent symptoms and show radiologic abnormalities after discharge. Herein, we present cases of four patients with previous COVID-19 infection manifesting pulmonary sequelae, including pulmonary fibrosis or organizing pneumonia pattern with persistent dyspnea after recovery.

Viral load and rebound in children with coronavirus disease 2019 during the first outbreak in Daegu city

  • Chu, Mi Ae;Jang, Yoon Young;Lee, Dong Won;Kim, Sung Hoon;Ryoo, Namhee;Park, Sunggyun;Lee, Jae Hee;Chung, Hai Lee
    • Clinical and Experimental Pediatrics
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    • v.64 no.12
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    • pp.652-660
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    • 2021
  • Background: Viral load and shedding duration are highly associated with the transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. However, limited studies have reported on viral load or shedding in children and adolescents infected with sudden acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Purpose: This study aimed to investigate the natural course of viral load in asymptomatic or mild pediatric cases. Methods: Thirty-one children (<18 years) with confirmed SARS-CoV-2 infection were hospitalized and enrolled in this study. Viral loads were evaluated in nasopharyngeal swab samples using real-time reverse transcription polymerase chain reaction (E, RdRp, N genes). cycle threshold (Ct) values were measured when patients met the clinical criteria to be released from quarantine. Results: The mean age of the patients was 9.8 years, 18 (58%) had mild disease, and 13 (42%) were asymptomatic. Most children were infected by adult family members, most commonly by their mothers. The most common symptoms were fever and sputum (26%), followed by cough and runny nose. Nine patients (29%) had a high or intermediate viral load (Ct value≤30) when they had no clinical symptoms. Viral load showed no difference between symptomatic and asymptomatic patients. Viral rebounds were found in 15 cases (48%), which contributed to prolonged viral detection. The mean duration of viral detection was 25.6 days. Viral loads were significantly lower in patients with viral rebounds than in those with no rebound (E, P=0.003; RdRp, P=0.01; N, P=0.02). Conclusion: Our study showed that many pediatric patients with coronavirus disease 2019 (COVID-19) experienced viral rebound and showed viral detection for more than 3 weeks. Further studies are needed to investigate the relationship between viral rebound and infectiousness in COVID-19.

Brief Summary on Nursing Studies regarding COVID-19

  • Hyun, Sookyung
    • International Journal of Advanced Culture Technology
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    • v.9 no.2
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    • pp.47-55
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    • 2021
  • The coronavirus disease 2019 (COVID-19) pandemic continuously influences on the health and well-being of people and communities worldwide. The purpose of this study was to explore the published research articles in the fields of nursing and health during the COVID-19 pandemic. The research design is an exploratory study. Samples are the abstracts of the articles from a literature database, PubMed, that were published from January 1st, 2020 to April 15th, 2021. We used a MeSH term, 'nursing' and "COVID-19" to retrieve articles that are related to COVID-19. Five hundred and fifty-five articles were retrieved. Two hundred and sixteen articles were excluded as they were not met the inclusion criteria. The total number of articles used in this study was three hundred and thirty-nine. The average number of articles published during the data collection period was 21.9. Seven topics were discovered from the abstracts of the articles: COVID-19 management and guidance; Perinatal COVID-19 and breastfeeding; Nurse; Health service and support; Patient care; Research; and Education and experience. This study revealed some interesting topics from the articles related to COVID-19 and provided some sense of research areas that may be interesting and allow us to develop important research questions about nursing science and nursing practice.

The Effect on the Immune System in the Human Body Due to COVID-19: An Insight on Traditional to Modern Approach as a Preventive Measure

  • Sutradhar, Jugal;Sarkar, Bapi Ray
    • Journal of Pharmacopuncture
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    • v.24 no.4
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    • pp.165-172
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    • 2021
  • The COVID-19, the most infectious pandemic disease arising due to SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) has caused huge issues globally. In this review, we discuss the impact of COVID-19 on the immune system of the human body and the protective mechanisms of the host immune system opposing viral infections. Here, we summarize the effect of the pandemic of the novel coronavirus disease on the immune system such as sleep and Behavioral Immune System (BIS) together with consideration of researcher's observation points of view. We draw particular attention to recent up-to-date reports concerning COVID-19 drugs as well as information about the landscape document for COVID-19 vaccines released by WHO (World Health Organization), and some adverse events of COVID-19 vaccination. Additionally, can take part in the preventive appraise in opposition within this pandemic severe COVID-19 infections disease may affect some outcome in physical exercise, physical movement, healthy diets, and good nutrition are significant for supporting the immune systems and summarize AYUSH (Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy) Indian medicinal systems guidelines for immunity boosting procedures during COVID-19 pandemic.

A Case of False Negativity With COVID-19 Diagnostic Test in Total Laryngectomee (코로나바이러스 감염증-19 진단검사에 위음성을 보인 후두전절제 환자 1예)

  • Beag, Moon Seung;Kwon, Hyeok Ro;Kim, Seung Woo
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.33 no.1
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    • pp.54-57
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    • 2022
  • The coronavirus disease (COVID-19) by severe acute syndrome coronavirus-2 (SARS-CoV-2) occurs the unprecedented pandemic during recent two years and the WHO declared a global pandemic of COVID-19 in March 2020. The most common sampling sites in COVID-19 test are the oropharynx and nasopharynx. We recently encountered a total laryngectomee who had a positivity COVID-19 diagnostic test from the tracheostoma, on the other hand, false negativity from the nasal cavity. The meaning of this case is that accurate screening test could be achieved by performing a test through the tracheostoma as well as nasal cavity or oropharynx. We also would like to discuss the accurate testing methods of patients whose airflow has distorted due to surgery, the management method of these patients, and the need of further research in the COVID-19 pandemic period with relevant literature reviews.

Clinical and Radiologic Findings of COVID-19 Pneumonia: South Korean Experience from Three Cases (코로나바이러스감염증-19의 임상적 소견 및 영상의학적 소견: 세 증례를 통한 한국의 경험)

  • Hyung Ju Lee;Jung Won Moon;Ji Young Woo;Yoo Na Kim
    • Journal of the Korean Society of Radiology
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    • v.81 no.3
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    • pp.583-590
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    • 2020
  • Coronavirus disease 2019 (COVID-19) is spreading rapidly around the world. Several articles have so far reported on radiological findings of COVID-19 pneumonia. Herein, we present three cases of COVID-19 pneumonia in South Korea, and provide clinical information as well as chest radiograph and chest CT findings.