• 한국임상수의학회지
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• 제28권6호
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• pp.562-565
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• 2011

2008년 1월부터 2010년 3월까지 만성 각막 상피 결손증으로 서울대학교 부속 동물병원에 내원한 환자 27마리 (25두: 단안, 2두: 양안)를 대상으로 점안마취 하에 격자 각막 절개법을 적용하였다. 처치 후 7-14일 간격으로 재진하였으며, 형광염색 시 음성이고, 각막 표면이 안정화될 때까지 반복 처치하였다. 이중 86.2%에 해당하는 25안에서 각막 궤양이 치유되었으며, 평균 치유기간은 $15.92{\pm}9.19$일 (7-39일)이었다. 병변이 악화되거나 각막 절개법을 최초로 시행 후 6주가 지나도 병변이 치유되지 않는 4안의 경우, 전신마취 하에 각막 절개법 및 제 3 안검 플랩을 적용하였으며, 2주 후 플랩을 제거했을 때, 병변이 모두 치유된 것을 확인하였다. 따라서, 각막 절개법은 만성 각막 상피 결손증에 유용한 치료법이라고 사료되며, 반복적인 처치에도 재발하거나 시술의 성공률을 높이기 위해서는 각막절개법과 제 3 안검 플랩을 함께 실시할 것이 추천된다.

• 한국임상수의학회지
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• 제28권5호
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• pp.533-537
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• 2011

13살 암컷 시츄 (증례 1) 와 10살 암컷 요크셔테리어 (증례 2) 가 각막 내피세포 변성증에 의한 각막궤양으로 내원하였다. 안검사 상에서 증례 2의 우안은 각막 외측에 국소적인 각막 부종이 확인되었고, 나머지 3 안에서는 전체 각막에서 부종이 확인되었다. 두 증례 모두 좌안에서 결막 충혈, 국소적인 각막 색소 침착, 각막 신생혈관화, 상피하수포가 관찰되었고, 형광 염색 시 양성 반응이 확인되었다. 각막열성형술은 증례 1 에서, 좌안의 전체 각막에, 증례 2에서, 좌안의 전체 각막과 우안의 각막부종 부위에 실시하였다. 증례 2 에서, 술 후 각막 치유를 촉진시키기 위해 일시적으로 양안 안검 봉합을 실시하여, 11일간 유지하였다. 각막 궤양은 증례 1 에서, 25일째, 증례 2 에서, 11 일째 완전히 치유되었다. 증례 1은 술 후 15 개월, 증례 2는 술 후 10 개월간 각각 각막궤양이 재발되지 않았다. 각막 색소 침착이 수술 전보다 진행되었으나, 그 외 임상적으로 중요한 부작용은 관찰되지 않았다. 각막 내피세포 변성증에 의한 궤양의 경우, 지속성 또는 재발성 양상으로 진행하여 심층 각막궤양 및 포도막염과 같은 속발증이 병발하는 경우가 많다. 그러므로, 본 증례에서 보고한 바와 같이 각막열성형술은 각막내피세포변성증에 의한 각막궤양에 효과적인 치료법으로 생각된다.

• 대한수의학회지
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• 제63권2호
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• pp.20.1-20.4
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• 2023

A 10-year-old, spayed female, Maltese dog presented with a 2-day history of severe left eye squint. Slit-lamp biomicroscopy showed a deep corneal defect stained into a doughnut shape together with hypopyon in the anterior chamber. Based on these results, a diagnosis of descemetocele and uveitis in the left eye was made. Deep keratotomy combined with a nictitating membrane flap effectively resolved the descemetocele without complications. The surgical procedures performed on this patient were easy and effective, and could be used as an alternative to graft surgery for descemetocele treatment.

• 한국임상수의학회지
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• 제22권3호
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• pp.278-280
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• 2005

A four-year-old intact female poodle was referred with a history of ocular discharge and corneal ulcer to Veterinary Medical Teaching Hospital of Seoul National University. The dog was diagnosed severe keratoconjunctivitis sicca (dry eye) on bilateral eye. As the dog was not response to the ophthalmic medication, acupuncture treatment was applied to the dog. After 2 months from treatment, the dog was completely recovered from keratoconjunctivitis sicca. It is suggested that traditional veterinary medicine might be effective alternative therapy for the patient with keratoconjunctivitis sicca.

• 한국임상수의학회지
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• 제27권5호
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• pp.610-613
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• 2010

체중 7.9 kg, 나이 8세의 수컷견이 좌측 안구의 돌출과 각막 부종 증세로 건국대학교 수의과대학 부속 동물병원에 내원하였다. 3년 전 좌안에 백내장 수술을 받은 병력이 있었다. 안과 검사상에서 좌안의 안압은 매우 높았으며 (47 mmHg), 눈부심반사는 음성이었다. 환축은 속발성 녹내장에 준하여 전신 및 국소적 약물 처치를 받았다. 약물 처치 후, 각막 부종은 감소되었으나, 좌안의 안압은 30-35 mmHg로 여전히 높은 상태를 보였다. 17개월 후, 환축은 우발적인 외상으로 인하여 전안방 출혈, 상공막 충혈과 각막 부종 상태를 보여 다시 내원하였다. 안구 외형을 보존하고 싶어하는 보호자의 요청에 따라 안구내 실리콘 보철물 삽입이 안구내용적출술을 통하여 실시되었다. 수술 3개월 후 좌안에 각막궤양이 발생하였으나, 약물 처치 후 호전되었다. 이후 1년까지 환축은 다른 합병증 없이 안정적인 상태를 보였다.

• 한국안광학회지
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• 제18권1호
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• pp.67-73
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• 2013

목적: 최근 시력 교정용 기구 및 주변용품들에 대한 미생물의 오염이 안과 질병요인으로 지목됨에 따라 시력 교정용 안경에 대한 세균의 오염 실태를 조사하였다. 방법: 초등학생 36명, 중학생 37명, 고등학생 30명, 대학생 10명, 노인 32명으로 총 145명의 안경으로부터 세균을 채취하여 분리 배양한 후 동정하였다. 결과: 시력 교정용 안경으로부터 검출된 세균은 총 17종으로 Bacillus cereus, Bacillus licheniformis, Bacillus sp., CNS, Enterococcus, Escherichia coli, Proteus sp., Pseudomonas sp., Serretia sp., Streptococcus sp., Staphylococcus epidermidis, Staphylococcus aureus, Streptococcus hemolyticus, Acinetobacter, Enterobacter cloacae, GNR, Pseudomonas aeruginosa이었다. 안과질환과 관련한 세균류는 각막염을 유발하는 Enterobacter cloacae, Pseudomonas aeruginosa, Staphylococcus epidermidis, 각막궤양을 유발하는 Pseudomonas sp., Staphylococcus aureus, 급성누낭염, 안와봉소염, 망막정맥주위염, 눈꺼풀테염을 유발하는 Staphylococcus aureus와 급성결막염 등을 유발하는 Streptococcus hemolyticus가 포함되었다. 결론: 시력 교정용 안경에서 고위험군 기회감염성 균류들이 다량으로 존재하는 것을 확인하였으며 이를 통한 감염에 따른 질병의 유발이 예측되므로 안경의 청결관리를 위한 대안이 필요하다고 사료된다.

• Parasites, Hosts and Diseases
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• 제42권3호
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• pp.93-119
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• 2004

Acanthamoeba and Naegleria are widely distributed in fresh water, soil and dust throughout the world, and cause meningoencephalitis or keratoconjunctivitis in humans and other mammals. Korean isolates, namely, Naegleria sp. YM-1 and Acanthamoeba sp. YM-2, YM-3, YM-4, YM-5, YM-6 and YM-7, were collected from sewage, water puddles, a storage reservoir, the gills of a fresh water fish, and by corneal washing. These isolates were categorized into three groups based on the mortalities of infected mice namely, highly virulent (YM-4), moderately virulent (YM-2, YM-5 and YM-7) and nonpathogenic (YM-3). In addition, a new species of Acanthamoeba was isolated from a freshwater fish in Korea and tentatively named Korean isolate YM-4. The morphologic characters of its cysts were similar to those of A. culbertsoni and A. royreba, which were previously designated as Acanthamoeba group III. Based on experimentally infected mouse mortality, Acanthamoeba YM-4 was highly virulent. The isoenzymes profile of Acanthamoeba YM-4 was similar to that of A. royreba. Moreover, an anti-Acanthamoeba YM-4 monoclonal anti-body reacted only with Acanthamoeba YM-4, and not with A. culbertsoni. Random amplified polymorphic DNA marker analysis and RFLP analysis of mitochondrial DNA and of a 188 small subunit ribosomal RNA, placed Acanthamoeba YM-4 in a separate cluster based on phylogenic distances. Thus Acanthamoeba YM-4 was identified as a new species, and assigned Acanthamoeba sohi. Up to the year 2002 in Korea, two clinical cases were found to be infected with Acanthamoeba spp. These patients died of meningoencephalitis. In addition, one case of Acanthamoeba pneumonia with an immunodeficient status was reported and Acanthamoeba was detected in several cases of chronic relapsing corneal ulcer, chronic conjunctivitis, and keratitis.

• 한국동물위생학회지
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• 제45권4호
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• pp.325-330
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• 2022

Distichiasis is one of the diseases commonly encountered in companion animals, and these abnormal eyelashes cause corneal ulcers, continuous eye irritation, eye pain, glare, epiphora, foreign body sensation and can cause corneal opacity and vision loss in severe cases. In this study, an eyelash epilation needle for animals was developed and applied to a real case, and the results were observed. In a case of corneal ulcer caused by distichiasis of a 2-year-old Shih Tzu, a high-frequency surgical instrument for animals was converted into an electric epilation needle to attempt a procedure to destroy the eyelash hair follicles on the upper eyelid. A epilation needle was developed to have a diameter of 0.1 mm and a length of 4 mm at the end of the handle of DOCTANZ 400, an electrosurgical instrument for animals only. In the procedure, 2~3 mm of an epilation needle was inserted into the hair follicle, and 1 watt of electric power was applied to the hair follicle for about 5 sec. to carry out electrolysis until white bubbles were generated around the meibomian glands thereby destroying the hair follicle. As a result, no eyelashes grew any longer in the treated area indicating that the treatment was successful. It is hoped that the method developed in this study will be applied so that it will be widely used as a treatment method for distichiasis in companion animals that can be frequently seen hereafter.

• 한국임상수의학회지
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• 제37권3호
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• pp.149-152
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• 2020

One-year-old male Cocker Spaniel dog was referred for the third eyelid enlargement and inflammation in the left eye (OS). It gradually swelled for 2 weeks after the cherry eye repair by conjunctival mucosa pocket procedure at a private animal clinic. Routine ophthalmic examinations including neuro-ophthalmic examination, Schirmer tear test, intraocular pressure and corneal fluorescein staining were all normal. No lesions were found on slit lamp biomicroscopy and indirect ophthalmoscopy except for third eyelid swelling in the OS. Ultrasonography revealed cystic structure within the OS nictitating membrane. Fluid from the cyst was aspirated and there were no microorganisms or neoplastic changes. Surgical intervention was performed under general anesthesia. On the day of the surgery, there was a deep corneal ulcer in the OS, which had not existed before. Ventral palpebral surface of the third eyelid was incised horizontally to the shaft of the T-shaped hyaline cartilage. And then, a full thickness of the cystic wall was incised and marsupialized. Additionally, a direct suture was performed on the ulcerated cornea. Topical and systemic antibiotics and anti-inflammatory drugs were prescribed. One month after the surgery, the third eyelid swelling and the discharge were improved. Marsupialization of the nictitating membrane cyst relieved the swelling of the third eyelid and inflammation. It could be a simple but effective surgical intervention for the cystic complication of conjunctival mucosa pocket procedure in dogs.

• 한국임상수의학회지
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• 제35권4호
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• pp.126-129
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• 2018

This study was performed to describe the outcome of pars plana retinopexy with perfluoro-n-octane (PFO)-silicone oil (SiO) exchange in dogs with rhegmatogenous retinal detachment in Seoul National University Veterinary Medical Teaching Hospital (SNU VMTH) from 2014 to 2017. Nine eyes of 8 dogs were included in this study. Medical records including signalment, history, duration from onset of blindness to surgical intervention, pre-operative findings, duration from surgery to regaining vision, and post-operative complications were evaluated. No eyes were visual before surgery. Duration from onset of blindness to surgical intervention was 2-30 days (median 8 days); duration from surgery to regain vision was 1-14 days (median 6 days); follow-up time was 15-1088 days (median 69 days). Post-operative complications were divided as temporary vs permanent conditions. Temporary complications were corneal ulcer, uveitis, retinal haemorrhage, glaucoma, subconjunctival leakage of SiO, and vitreal haemorrhage. Permanent complications were anterior chamber migration of SiO, retinal degeneration, corneal degeneration, re-detachment, and cataract. Six of 9 eyes regained functional vision, five of which remained visual throughout the follow-up time while the other one lost vision after 3 months because of uveitic glaucoma. In conclusion, pars plana retinopexy with PFO-SiO exchange provided fair outcome in 66.7% cases described in this study.