• Title/Summary/Keyword: Core2

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The Action of Hepatitis B Virus Enhancer 2-Core Gene Promoter in Non-Viral and Retroviral Vectors for Hepatocyte-Specific Expression

  • Rih, Jeong-Keun;Oh, Sang-Taek;Hwang, Deog-Su;Kim, Sun-Young;Yim, Jeong-Bin
    • BMB Reports
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    • v.30 no.4
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    • pp.269-273
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    • 1997
  • Heptocvte-specific expression induced by Hepatitis B virus (HBV) enhancer 2-core gene promoter was examined in various hepatocyte and non-hepatocyte cell lines. using non-viral and retroviral vector systems in which chloramphenicol acetyltransferase (CAT) is used as a reporter. The non-viral plasmid containing the HBV enhancer 2-core promoter exhibited 22 and 66% of CAT activities in hepatoma cell lines. HepG2 and Hep3B, respectively when compared with CAT activity expressed by CMV promoter. The CAT activities, however. were found to be marginal in other tested hepatoma cell lines as well as mouse primary hepatocytes and non-hepatocytes. The HBV enhancer 2 located upstream the CMV promoter did not affect the CMV promoter activity nor provided hepatocyte-specific expression. Transfection of retroviral plasmid DNA containing the HBV enhancer 2-core promoter as an internal promoter exhibited high and specific CAT expression in HepG2 and Hep3B cell lines but the activity value was 5 to 10 fold lower than the non-viral plasmid with identical promoter. These results suggest that the usage of HBV enhancer 2-core promoter for liver specific expression is limited to certain vectors and hepatocyte cell lines.

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A Study on Region Gateway-based Data Transmission in IoT Environment (IoT 환경에서의 지역 Gateway 기반 데이터 전송에 관한 연구)

  • Cho, Kyoung-Woo;Oh, Chang-heon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2017.10a
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    • pp.531-532
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    • 2017
  • OneM2M's domain is divided into Device, Network, and Application domain, and data generated from various devices is collected through IoT/M2M gateway, it is delivered to appropriate IoT/M2M Infrastructure through Core/Access Network. However, access to the Core/Access Network is also required if the device transmit data to an Infrastructure located within the same area. In this paper, it propose data transmission based on region gateway that judge and transmit local information of data by adding a concept of region network domain to oneM2M domain, prevent access to unnecessary Core/Access Network.

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Interfacial Electric Property of PVA/PVAc Particles (PVA/PVAc 입자의 계면 전기적 성질)

  • Lee, Ha-Na;Lee, Jae-Woong;Kim, Ji-Young;Lee, Won-Chul;Kim, Sam-Soo
    • Textile Coloration and Finishing
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    • v.20 no.6
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    • pp.8-17
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    • 2008
  • Poly (vinyl acetate) (PVAc) was used as a precursor of PVA/PVAc (skin/core) bicomponent. In order to investigate the possibility of PVA particles for electrical applications, PVA/PVAc particles were produced with an emulsifier, SDS (Sodium Dodecyl Sulfate) and an initiator, V-50 (2,2'-azobis(2-amidinopropane)digydrochloride). In this study, we investigated the electrical property of PVA/PVAc (skin/core) particles. The hydroxyl group of the PVA/PVAc (skin./core) was confirmed by the analysis of PVAc and PVA/PVAc (skin/core) using Fourier Transform Infrared Spectroscopy (FT-IR). The zeta-potential of the PVA/PVAc (skin/core) and PVAc has similarity; however, charge control agent (CCA) treated PVA/PVAc (skin/core) particles has lower zeta-potential than untreated PVA/PVAc particles. The zeta-potential (negative values) of the PVA/PVAc (skin/core) were enhanced in proportion to the increased concentration of CCA.

Experimental Estimation on Magnetic Friction of Superconductor Flywheel Energy Storage System

  • Lee, Jeong-Phil;Han, Sang-Chul;Park, Byeong-Choel
    • Journal of Magnetics
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    • v.16 no.2
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    • pp.124-128
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    • 2011
  • This study estimated experimentally the loss distribution caused by magnetic friction in magnetic parts of a superconductor flywheel energy storage system (SFES) to obtain information for the design of high efficiency SFES. Through the spin down experiment using the manufactured vertical shaft type SFES with a journal type superconductor magnetic bearing (SMB), the coefficients of friction by the SMB, the stator core of permanent magnet synchronous motor/generator (PMSM/G), and the leakage flux of the metal parts were calculated. The coefficients of friction by the stator core of PMSM/G in case of using Si-steel and an amorphous core were calculated. The energy loss by magnetic friction in the stator core of PMSM/G was much larger than that in the other parts. The level of friction loss could be reduced dramatically using an amorphous core. Energy loss by the leakage magnetic field was small. On the other hand, the energy loss could be increased under other conditions according to the type of metal nearby the leakage magnetic fields. In manufactured SFES, the rotational loss by the amorphous core was approximately 2 times the loss of the superconductor and leakage. Moreover, the rotational loss by the Si-steel core is approximately 3~3.5 times the loss of superconductor and leakage.

80μW/MHz 0.68V Ultra Low-Power Variation-Tolerant Superscalar Dual-Core Application Processor

  • Kwon, Youngsu;Lee, Jae-Jin;Shin, Kyoung-Seon;Han, Jin-Ho;Byun, Kyung-Jin;Eum, Nak-Woong
    • IEIE Transactions on Smart Processing and Computing
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    • v.4 no.2
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    • pp.71-77
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    • 2015
  • Upcoming ground-breaking applications for always-on tiny interconnected devices steadily demand two-fold features of processor cores: aggressively low power consumption and enhanced performance. We propose implementation of a novel superscalar low-power processor core with a low supply voltage. The core implements intra-core low-power microarchitecture with minimal performance degradation in instruction fetch, branch prediction, scheduling, and execution units. The inter-core lockstep not only detects malfunctions during low-voltage operation but also carries out software-based recovery. The chip incorporates a pair of cores, high-speed memory, and peripheral interfaces to be implemented with a 65nm node. The processor core consumes only 24mW at 350MHz and 0.68V, resulting in power efficiency of $80{\mu}W/MHz$. The operating frequency of the core reaches 850MHz at 1.2V.

Development of a Core Set of Korean Soybean Landraces [Glycine max(L.) Merr.]

  • Cho, Gyu-Taek;Yoon, Mun-Sup;Lee, Jeong-Ran;Baek, Hyung-Jin;Kang, Jung-Hoon;Kim, Tae-San;Paek, Nam-Chon
    • Journal of Crop Science and Biotechnology
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    • v.11 no.3
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    • pp.157-162
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    • 2008
  • A total of 2,765 accessions were used as the initial set having both seed coat color and 100-seed weight data. As a result of molecular profiling using six SSR markers followed by stratification based on their usages, 335 accessions(12.1%) were selected by clustering based on UPGMA. Since 75 out of 335 accessions were mixed in phenotypic traits as a result of characterization, 260 accessions were finally set as a core set. This core set revealed nearly the same diversity compared with the other results on morphological traits of Korean soybean landraces. In total, 115 alleles(19.2 alleles per locus) were detected in the initial set and 79 alleles(13.2 alleles per locus) were detected in the core set. All 30 major alleles were present in the initial set and in the core set as well. In allele coverage, the core set was 71.4% of the initial set. These comparisons of number of alleles, gene diversity and coverage indicated that the core set represented the entire set well.

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A STUDY ON THE MATERIAL PROPERTIES OF VARIOUS COMPOSITE RESINS FOR CORE BUILD-UP (수종 코어용 복합레진 수복재의 물성에 관한 연구)

  • Shin, Soo-Il;Shin, Dong-Hoon
    • Restorative Dentistry and Endodontics
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    • v.29 no.2
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    • pp.191-199
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    • 2004
  • The purposes of this study were to estimate the material properties of the recently developed domestic composite resins for core filling material (Chemical, Dual A, Dual B;Vericom, Korea) and to compare them with other marketed foreign products (CorePaste, Den-Mat, USA;Ti-Core, Essential Dental Systems, USA;Support. SCI-Pharm. USA). Six assessments were made:working time. setting time. depth of polymerization. flexural strength. bonding strength. and marginal leakage. All items were compared to ISO standards. All domestic products satisfied the minimum requirements from ISO standards (working time:above 90 seconds. setting time:within 5 minutes). and showed significantly higher flexural strength than Core Paste. Dual A and B could. especially. reduce the setting time to 60 seconds when cured with $600mW/cm^2$ light intensity. All experimental materials showed 6 mm depth of polymerization. Bond strengths of Ti-Core and Dual B materials were significantly higher than the other materials. Furthermore. three domestic products and Ti-Core could reduce the microleakage effectively.

Concept Development of Core Protection Calculator with Trip Avoidance Function using Systems Engineering

  • Nascimento, Thiago;Jung, Jae Cheon
    • Journal of the Korean Society of Systems Engineering
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    • v.16 no.2
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    • pp.47-58
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    • 2020
  • Most of the reactor trips in Korean NPPs related to core protection systems were caused not because of proximity of boiling crisis and, consequently, a damage in the core, but due to particular miscalculations or component failures related to the core protection system. The most common core protection system applied in Korean NPPs is the Core Protection Calculator System (CPCS), which is installed in OPR1000 and APR1400 plants. It generates a trip signal to scram the reactor in case of low Departure from Nucleate Boiling Ratio (DNBR) or high Local Power Density (LPD). However, is a reactor trip necessary to protect the core? Or could a fast power reduction be enough to recover the DNBR/LPD without a scram? In order to analyze the online calculation of DNBR/LPD, and the use of fast power reduction as trip avoidance methodology, a concept of CPCS with fast power reduction function was developed in Matlab® Simulink using systems engineering approach. The system was validated with maximum of 0.2% deviation from the reference and the dynamic deviation was maximum of 12.65% for DNBR and 6.72% for LPD during a transient of 16,000 seconds.

EFFECT OF CORE-SHELL PARTICLES ON PHYSICAL PROPERTIES OF DENTAL COMPOSITES (고무상입자가 치과용 복합레진의 물리적 성질에 미치는 영향)

  • Choi, Kyoung-Kyu
    • Restorative Dentistry and Endodontics
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    • v.23 no.2
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    • pp.690-700
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    • 1998
  • Rubber-toughened particles which are used in the field of chemical engineering are used to increase the fracture toughness of thermoset resin. The application of Core-Shell particles, one of rubber-toughened particles, as a filler for dental composite or restoration have not been examined. The purpose of this study was to evaluate possible use of Core-Shell particles for dental composite, and the hypothesis was that additional toughening mechanisms are activated by the addition of Core-Shell particles. After blending 50vol% quartz with Bis-GMA/TEGDMA resin matrix, the experimental resins were made by the addition of Core-Shell particles with varied content level as 0, 2.5, 5, 7.5, 10, 12.5, 15, and 20wt%. Fracture toughness was determined on three-point bending specimen with single-edge notch according to ASTM-E 399. Also, flexural properties, that is, strength and modulus were measured by three-point bending testing. Fractogragh of fracture toughness specimen was observed using SEM (JEOL 6400 SEM, MA). The following results from this study were obtained ; 1. Fracture toughness of composite resin added 2.5wt% Core-Shell particles was significantly higher than control group ($p{\leq}0.05$). 2. Flexural properties were decreased with increasing Core-Shell particle content, which showed a correlation statistically ($p{\leq}0.05$). 3. A toughening mechanism such as lamination and microcrack was observed in specimen determined high fracture toughness. 4. The dispersion of Core-Shell itself and quartz filler particles was limited present high content of Core-Shell particles, which decreased a resulting mechanical properties of composites. These results suggest that adequate Core-Shell particles can be used to enhance mechanical properties included toughening for dental composites.

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Synthesis and Characterization of Au/TiO2 Nanoparticles with Core-shell Structure (Core-shell 구조의 Au/TiO2 나노 미립자의 합성 및 특성 평가)

  • ;Paul Mulvaney
    • Journal of the Korean Ceramic Society
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    • v.40 no.9
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    • pp.902-908
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    • 2003
  • Au/TiO$_2$ core-shell structure nanoparticles were synthesised by sol-gel process, and the morphology and crystallinity of TiO$_2$ shell were investigated by TEM and UV-Vis. absorption spectrometer. Au/TiO$_2$ core-shell structure nanoparticles could be prepared by the hydrolysis of TOAA (Titanium Oxide Acethylacetonate) in Au colloid ethanol solution with $H_2O$. The thickness of TiO$_2$ shell on the surface of Au particles was about 1 nm. To investigate the crystallinity of TiO$_2$ shell, UV light with 254 nm and radioactive lay of $^{60}$ CO were irradiated on the TiO$_2$ coated Au colloid ethanol solution. The surface plasmon phenomenon of Au nanoparticles appeared only when the radioactive lay was irradiated on the TiO$_2$ coated Au colloid ethanol solution. From these results, it was found that the TiO$_2$ shell was amorphous and the MUA (Mercaptoundecanoic Acid) layer on the Au particle for its dispersion didn't act as an obstacle to disturb the movement of electron onto the surface of Au particle.