• 한국정보과학회논문지:소프트웨어및응용
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• 제32권9호
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• pp.835-846
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• 2005

제품계열(Product Line)은 핵심자산(Core Asset)을 서로 공유하는 제품들의 집합이며, 제품계열 공학(Product Line Engineering, PLE)은 제품계열을 특화(Instantiation) 할 수 있는 원리, 기술, 메커니즘과 프로세스들의 집합이다. PLE는 여러 유사한 제품들간에 공유할 수 있는 핵심자산을 만들고, 그 핵심자산을 특정 제품에 맞게 실체화 시켜서 제품을 만든다. 모델 기반 아키텍처(Model Driven Architecture, MDA)는 자동화 도구를 이용하여 모델로부터 구현으로 구체화하는 접근 방법이다. 그러므로, 핵심자산을 MDA의 플랫폼 독립적인 모델(PIM)로 정의하여 구현까지 자동화한다면, 두 개발 방법의 장점을 극대화 할 수 있다. 하지만, 핵심자산을 표현하는 UML 프로파일은 현재까지 없으며, PLE의 핵심자산 및 제품 조림의 자동화 생산을 위한 PIM 명세 기법의 연구가 부족하다. 본 논문에서는 PLE기술과 MDA 기술을 접목하기 위해 PIM 수준의 핵심자산 명세 기법을 제안한다. 핵심자산을 명세하기 위해 아키텍처 명세, 컴포넌트 명세, 워크플로우 명세, 알고리즘 명세, 결정 모델 명세 기법을 제안한다. 본 논문의 명세 기법은 PLE, MDA 기술을 사용하여 제품의 생산성, 적용성, 유지보수성 및 품질 향상을 지원한다.

• Nuclear Engineering and Technology
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• 제45권6호
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• pp.767-790
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• 2013

MAAP4 is a computer code that can simulate the response of a light water reactor power plant during severe accident sequences, including actions taken as part of accident management. The code quantitatively predicts the evolution of a severe accident starting from full power conditions given a set of system faults and initiating events through events such as core melt, reactor vessel failure, and containment failure. Furthermore, models are included in the code to represent the actions that could mitigate the accident by in-vessel cooling, external cooling of the reactor pressure vessel, or cooling the debris in containment. A key element tied to using a code like MAAP4 is an uncertainty analysis. The purpose of this paper is to present a MAAP4 based analysis to examine the sensitivity of a key parameter, in this case hydrogen production, to a set of model parameters that are related to a Level 2 PRA analysis. The Level 2 analysis examines those sequences that result in core melting and subsequent reactor pressure vessel failure and its impact on the containment. This paper identifies individual contributors and MAAP4 model parameters that statistically influence hydrogen production. Hydrogen generation was chosen because of its direct relationship to oxidation. With greater oxidation, more heat is added to the core region and relocation (core slump) should occur faster. This, in theory, would lead to shorter failure times and subsequent "hotter" debris pool on the containment floor.

• Bulletin of the Korean Chemical Society
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• 제28권4호
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• pp.561-566
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• 2007

Adenosine kinase (AK) is a ubiquitous intracellular enzyme, which catalyzes the phosphorylation of adenosine (ADO) to adenosine monophosphate (AMP). AK inhibitors have therapeutic potential as analgesic and antiinflammatory agents. A chemical feature based pharmacophore model has been generated from known AK inhibitors (26 training set compounds) by HypoGen module implemented in CATALYST software. The top ranked hypothesis (Hypo1) contained four features of two hydrogen-bond acceptors (HBA) and two hydrophobic aromatics (Z). Hypo1 was validated by 124 test set molecules with a correlation coefficient of 0.905 between experimental and estimated activity. It was also validated by CatScramble method. Thus, the Hypo1 was exploited for searching new lead compounds over 238,819 chemical compounds in NCI database and then the selected compounds were screened based on restriction estimated activity and Lipinski's rules to evaluate their drug-like properties. Finally we could obtain 72 new lead candidates and the two best compound structures from them were posted.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2001년도 하계종합학술대회 논문집(2)
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• pp.117-120
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• 2001

This paper presents a HW/SW co-design environments and its validation for development of virtual component on the 32-bit RISC core which is used in the design of Information-Appliance-On-a-Chip. For the experimental environment, we developed the cycle-accurate instruction set simulator based on SE3208 RISC core of ADChips. To verify the function of RISC core at the cycle level, we implemented the verification environment by grafting this simulator on the Seamless CVE which is a commercial co-verification environment.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2012년도 전력전자학술대회 논문집
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• pp.625-626
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• 2012

A coupled magnetic resonance system (CMRS) using compact coil sets with core driven by a class-E inverter was proposed. The source and load coils of conventional CMRS were replaced with two coils containing core so that the system can be quite compact in size and easy to design due to a resonance frequency for all resonant tanks regardless of coupling factor. Experiments for 500 kHz switching frequency show 40% system efficiency.

• ETRI Journal
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• 제37권1호
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• pp.118-127
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• 2015

The power consumption of 3D many-core processors can be reduced, and the power delivery of such processors can be improved by introducing voltage island (VI) design using on-chip voltage regulators. With the dramatic growth in the number of cores that are integrated in a processor, however, it is infeasible to adopt per-core VI design. We propose a 3D many-core processor architecture that consists of multiple voltage clusters, where each has a set of cores that share an on-chip voltage regulator. Based on the architecture, the steady state temperature is analyzed so that the thermal characteristic of each voltage cluster is known. In the voltage scaling and task scheduling stages, the thermal characteristics and communication between cores is considered. The consideration of the thermal characteristics enables the proposed VI formation to reduce the total energy consumption, peak temperature, and temperature gradients in 3D many-core processors.

• 한국정보통신학회논문지
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• 제5권6호
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• pp.1083-1088
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• 2001

본 연구에서는 내부도메인 멀티캐스트 라우팅 프로토콜중의 하나인 CBT(core-based tree) 프로토콜에서 발생하기 쉬운 코어라우터로의 트래픽 집중 철상을 해결하기 위해 지정코어라우터에 트래픽 폭주가 발생했을 때 멀티캐스트 그룹 가입자로 하여금 동적으로 코어를 변경할 수 있도록 하는 방안을 제시한다.

• Nuclear Engineering and Technology
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• 제34권2호
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• pp.117-131
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• 2002

Core disruptive accidents have been investigated at Korea Atomic Energy Research Institute(KAERI) as part of the work to demonstrate the inherent and ultimate safety of conceptual design of the Korea Advanced Liquid Metal Reactor(KALIMER), a 150 MWe pool- type sodium cooled prototype fast reactor that uses U-Pu-Zr metallic fuel. In this study, a simple method and associated computer program, SCHAMBETA, was developed using a modified Bethe-Tait method to simulate the kinetics and thermodynamic behavior of a homogeneous spherical core over the period of the super-prompt critical power excursion induced by the ramp reactivity insertion. Calculations of the energy release during excursions in the sodium-voided core of the KALIMER were subsequently performed using the SCHAMBETA code for various reactivity insertion rates up to 100 S/s, which has been widely considered to be the upper limit of ramp rates due to fuel compaction. Benchmark calculations were made to compare with the results of more detailed analysis for core meltdown energetics of the oxide fuelled fast reactor. A set of parametric studies were also performed to investigate the sensitivity of the results on the various thermodynamics and reactor parameters.

• 소성∙가공
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• 제16권7호
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• pp.530-537
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• 2007

This paper is concerned with the analysis of plastic deformation of bimetal co-extrusion process. Two sets of material combination have been adopted for analysis, i.e. combinations of Cu/Al and Fe/Al. In the first set of material combination, the selected materials are AA 1100 aluminum alloy as hard material and CDA 110 as soft one. This type of material selection is to examine the effect of hard core and soft sleeve and vice versa on the deformation pattern in terms of plastic zone and velocity discontinuity along the contact surface between construction materials. Four different cases of co-extrusion process in terms of material combination and interference bonding were simulated to investigate the effect of material arrangement between core and sleeve, and of bonding on the plastic zones and velocity discontinuity. In the other set of material combination, model materials used as core and sleeve were AA 1100 and AISI 1010, which are relatively soft and hard, respectively. Process parameters except diameter ratio of core to sleeve material such as semi-die angle, reduction in area in global sense and die comer radius have been set constant throughout the simulation to concentrate our effort on the analysis of influence of diameter ratio on deformation behavior such as deformation zone, surface expansion, exit velocity discontinuity between composite materials, and extrusion forces.

• Bulletin of the Korean Chemical Society
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• 제31권11호
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• pp.3333-3340
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• 2010

A three dimensional pharmacophore model was generated for the molecules which are responsible for anti-inflammatory activities targeting Interleukin-2 inducible tyrosine kinase (Itk). 16 structurally diverse molecules were selected as training set to generate the hypotheses using Discovery Studio v2.1. The best hypothesis, Hypo1, comprises two hydrogen bond acceptor (HBA), one hydrophobic aromatic (HA), one ring aromatic (RA) and shows high cost difference (63.71), high correlation coefficient (0.97) as well as low RMS deviation (0.81). Hypo1 has been further validated toward a test set, decoy set and Fischer's randomization method. Furthermore, Hypo1 was used to screen NCI and Maybridge databases. Finally, 2 hit molecules were identified as potential leads against Itk, which may be useful for future drug development.