• Title/Summary/Keyword: Copper/low k

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Mechanisms of Cadmium Carcinogenicity in the Gastrointestinal Tract

  • Bishak, Yaser Khaje;Payahoo, Laleh;Osatdrahimi, Alireza;Nourazarian, Alireza
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.1
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    • pp.9-21
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    • 2015
  • Cancer, a serious public health problem in worldwide, results from an excessive and uncontrolled proliferation of the body cells without obvious physiological demands of organs. The gastrointestinal tract, including the esophagus, stomach and intestine, is a unique organ system. It has the highest cancer incidence and cancer-related mortality in the body and is influenceed by both genetic and environmental factors. Among the various chemical elements recognized in the nature, some of them including zinc, iron, cobalt, and copper have essential roles in the various biochemical and physiological processes, but only at low levels and others such as cadmium, lead, mercury, arsenic, and nickel are considered as threats for human health especially with chronic exposure at high levels. Cadmium, an environment contaminant, cannot be destroyed in nature. Through impairment of vitamin D metabolism in the kidney it causes nephrotoxicity and subsequently bone metabolism impairment and fragility. The major mechanisms involved in cadmium carcinogenesis could be related to the suppression of gene expression, inhibition of DNA damage repair, inhibition of apoptosis, and induction of oxidative stress. In addition, cadmium may act through aberrant DNA methylation. Cadmium affects multiple cellular processes, including signal transduction pathways, cell proliferation, differentiation, and apoptosis. Down-regulation of methyltransferases enzymes and reduction of DNA methylation have been stated as epigenetic effects of cadmium. Furthermore, increasing intracellular free calcium ion levels induces neuronal apoptosis in addition to other deleterious influence on the stability of the genome.

Effect of Printing Qualities on the Resonant Frequencies of Printed UHF RFID Tag Antennas (인쇄 UHF RFID 태그 안테나의 인쇄 품질에 따른 공진 주파수의 영향)

  • Kim, Chung-Hwan;Lee, Yong-Shik;Kim, Young-Guk;Kim, Dong-Soo
    • Journal of the Korean Society for Precision Engineering
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    • v.25 no.11
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    • pp.90-94
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    • 2008
  • Recently, a great deal of research is focused on the printed electronics. One of their mainly concerned products is printed RFID tag. RFID technology has attracted researchers and enterprises as a promising method for automatic identification, and they are expected to replace conventional bar codes in inventory tracking and management. The key to successful RFID technology lies in developing low-cost RFID tags and the first step in applying printing technology to RFID systems is to replace antennas that are conventionally produced by etching copper or aluminum. However, due to the printing quality variations, errors, and lower conductivity, the performance of the printed RFID antennas is lower than that of antennas manufactured by conventional etching methods. In this paper, the effect of variations in the printing conditions on the antenna performance is investigated. Three levels for each condition parameter is assumed and effect on the resonant frequency are examined experimentally based on orthogonal array. The most serious factor that affects the resonant frequency of the antenna is the non-uniformity of the edge and the resonant frequency is found to be lower as the non-uniformity increases.

Fabrication and Characteristics of 150ℓ Class Hydrogen Tank Using Hydrogen Storage Alloy (수소저항합금을 이용한 150ℓ급 수소저장용기의 제작과 특성에 관한 연구)

  • Kang, Kll-Ku;Gang, Sei-Sun;Kwon, Ho-Young;Lee, Rhim-Youl
    • Transactions of the Korean hydrogen and new energy society
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    • v.13 no.2
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    • pp.110-118
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    • 2002
  • The hydrogen storage vessel having a good heat conductivity along with a simple structure and a low cost for these alloys was designed and manufactured, and then its characteristic properties were studied in this study. The various parts in hydrogen storage vessel consisted of copper pipes and stainless steel of 250 mesh reached the setting temperature after 4~5 minutes, which indicated that storage vessel had a good heat conductivity that was required in application. And also the storage vessel had a good property of hydrogen transport considering that the reaction time between hydrogen and rare-earth metal alloys in storage vessel was found to be within 10 min at $18^{\circ}C$ under 10 atmospheric pressure. It showed that the average capacity of discharged hydrogen volume was found to be $120{\ell}$ for $MmNi_{4.5}Mn_{0.5}$ under discharging conditions of $40^{\circ}C{\sim}80^{\circ}C$ at a constant flow rate of $5{\ell}$/min. It was found that the optimum discharging temperature for obtaining an appropriate pressure of 3atm was determined to be $60^{\circ}C$ for $MmNi_{4.5}Mn_{0.5}$ hydrogen storage alloy.

Phytoremediation of Cu-contaminated Soil and Water by Commelina communis

  • Kim, Sung-Hyun;Lee, In-Sook
    • The Korean Journal of Ecology
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    • v.28 no.1
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    • pp.7-13
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    • 2005
  • In the present study, we investigated the tolerance of Commelina communis to growth in Cu-contaminated soil and water We examined the germination rate, root and shoot growth of seedlings, fresh biomass in soil and water, and ability to eliminate Cu. We found that C. communis eliminated 41% of Cu in soil containing 50 mg Cu/kg and removed over 50% of Cu from water containing 100 mg Cu/L Cu. In addition, the plants could accumulate 90 mg Cu/g when grown in soil containing 50 mg Cu/kg and 140 mg Cu/g when grown in soil containing 100 mg Cu/kg thus higher levels of Cu removal were observed in soils containing higher Cu concentrations. In water, the maximal accumulation rate was 4.9 mg Cu/g root and 1.2 mg Cu/g shoot in water containing 20 mg Cu/L, and 7 days after exposure, Cu absorption saturated. Further, the growth rate of C. communis was not affected by up to 100 mg Cu/kg in the soil. Therefore, the phytotoxic effect of Cu on plants increased as the concentration of Cu was raised, although to different extents depending on whether the Cu was in soil or water. Overall, Cu removal from soil by C. communis was most effective at 100 mg Cu/kg in soil and 10 mg Cu/L in water. Finally, we identified two peaks of Cu-binding ligands in C. communis. Which is a high molecular weight peak (HMWL) at 60 kDa (Fraction 17 to 25) and a Cu binding peptide peak at <1 kDa (Very low molecular weight ligand: VLMWL). Cu-binding peptide (Cu-BP) was observed to have an amino acid composition typical of phytochelations.

Fabrication of Microwave PECVD with Linear Antenna for large-scale deposition processing, and Analysis of Ar plasma characteristics using Electrostatic Probe and Temperature Characteristics (대면적 증착용 선형 초고주파 플라즈마 장치 제작 및 정전 탐침법을 이용한 Ar 플라즈마 특성 분석과 온도 특성 분석)

  • Han, Moon-Ki;Seo, Kwon-Sang;Kim, Dong-Hyun;Lee, Ho-Jun
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.64 no.3
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    • pp.422-428
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    • 2015
  • A 2.45GHz microwave plasma source with a linear antenna has been developed for low temperature large scale deposition processing. Microwave power is transmitted through WR340 waveguide and a copper rod, linear antenna, is located in a quartz tube. The power matching is effectively achieved by a linear antenna is located at ${\lambda}_g/4$ or $3{\lambda}_g/4$ from the end of WR340 waveguide. The Ar plasma was generated along the surface of quartz tube and a clear standing wave pattern with nearly 10cm wavelength was observed at Ar pressure of 200mTorr and 200W input power. The electron density and electron temperature were investigated by using the electrostatic probe. The electron density and electron temperature were highly measured near the surface of quartz tube. Ar plasma density along the quartz tube is mostly uniform despite standing wave set-up and antenna of long length. A uniform temperature was measured at 10~40cm distance from the end quartz tube and 5cm distance from the surface of quartz tube.

A Study of Construction and Efficacy of Thermal Field-Flow Fractionation (열 장 흐름 분획장치의 제작과 효율성에 관한 연구)

  • Dai-Woon Lee;Wook-Hwan Heo;Jeon Sun-Joo;In-Ho Lee
    • Journal of the Korean Chemical Society
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    • v.36 no.3
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    • pp.419-427
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    • 1992
  • The performance of homemade thermal field-flow fractionation (ThFFF) and the optimization for separation are investigated in terms of retention parameters and selectivity using polystyrene standards. The ribbonlike channel was constructed by sandwiching two Mylar spacers between two highly polished copper bars which serve as channel walls. The hot bar was heated by two electrical cartridge heaters and the cold bar had holes through the entire length, allowing tap water as coolant to enter. It has been observed that the retention of polystyrenes increases as the temperature gradient increases. And the retention decreases as the cold wall temperature increases from 20 to $45^{\circ}C$. In comparison with size exclusion chromatography, ThFFF is more selective but has relatively low efficiency. It has been found that the plate height is proportional to the flow velocity and good estimates of polydispersities can be made directly from the ThFFF data.

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Comparative Study on the Efficiency of the Gas Discharge Lasers - Limiting Efficiency of Metal Vapor Lasers - (기체방전 레이저의 효율에 관한 연구 -금속증기레이저의 한계효율-)

  • 이재경
    • Korean Journal of Optics and Photonics
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    • v.4 no.1
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    • pp.47-56
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    • 1993
  • Practical efficiencies of pulsed gas discharge lasers utilizing vaporized Au, Ba, Cu, Fe, Mn, Pb, TI atoms are numerically optimized for a discharge pulse of 30 ns rise time at 5 kHz pulse repetition rate. Calculated optimum operating temperatures are close to the values at which the vapor pressure of each atom is about 1 Torr and are in good agreement with experimental values reported elasewhere. The optimum charging voltage was about 4 kV for all atomic vapor lasers except the TI laser. The calculated maximum efficiencies that have been discussed for possible limiting efficiencies for each laser were considerably higher than the reported experimental values. Especially, they were as high as 6.8% for Mn laser and 15% for Ba laser that were comparable to the 8.5% of copper vapor laser, from which considerably higher efficiencies can be expected for these two lasers experimentally. But, the present calculation shows a very low efficiency of 0.058% and requires an exceptional operating condition for the TI laser.

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The Effects of Mn-doping and Electrode Material on the Resistive Switching Characteristics of ZnOxS1-x Thin Films on Plastic

  • Han, Yong;Cho, Kyoungah;Park, Sukhyung;Kim, Sangsig
    • Transactions on Electrical and Electronic Materials
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    • v.15 no.1
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    • pp.24-27
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    • 2014
  • In this study, the effects of Mn-doping and the electrode materials on the memory characteristics of $ZnO_xS_{1-x}$ resistive random access memory (ReRAM) devices on plastic are investigated. Compared with the undoped Al/$ZnO_xS_{1-x}$/Au and Al/$ZnO_xS_{1-x}$/Cu devices, the Mn-doped ones show a relatively higher ratio of the high resistance state (HRS) to low resistance state (LRS), and narrower resistance distributions in both states. For the $ZnO_xS_{1-x}$ devices with bottom electrodes of Cu, more stable conducting filament paths are formed near these electrodes, due to the relatively higher affinity of copper to sulfur, compared with the devices with bottom electrodes of Au, so that the distributions of the set and reset voltages get narrower. For the Al/$ZnO_xS_{1-x}$/Cu device, the ratio of the HRS to LRS is above $10^6$, and the memory characteristics are maintained for $10^4$ sec, which values are comparable to those of ReRAM devices on Si or glass substrates.

Design and Modeling of the Embedded Meander line and Radial/T Stub for low-cost SOP (저가용 SOP를 위한 적층형 Meander와 Radial/T Stub의 설계와 모델링)

  • Cheon, Seong-Jong;Yang, Chang-Soo;Lee, Seung-Jae;Park, Jae-Yeong
    • Proceedings of the KIEE Conference
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    • 2006.07c
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    • pp.1591-1592
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    • 2006
  • 이동 및 정보통신 시스템이 소형화 및 고성능화됨에 따라 System OR Package (SOP) 기술의 연구개발이 주목을 받고 있다. 저가형 SOP를 위하여 가장 많은 연구가 다층인쇄회로 기판에 수동소자 및 전송선로를 내장시키는 것이다. 본 논문에서는, 8층 KB 기판에 Meander line과 Radial/T Stub 패턴을 Advanced Design System(ADS) simulation을 이용하여 설계 및 제작하고 분석함으로써 정확한 SOP 디자인 및 설계 방향을 제시하고자 한다. 설계변수-패턴의 length, width, spacing, 각도와 공정변수-1층/3층, 기판 재질(prepreg(PP)과 resin coated copper(RCC))을 두어 제작하여 그 특성을 비교하였다. Meander Line는 PP보다 RCC에서의 인덕턴스가 크고 높은 자가 공진주파수를 가졌고, 3층보다 1층에서의 인덕턴스가 안정적이었다. Radial/T Stub는 PP보다 RCC에서의 커패시턴스가 작으나, 높은 자가 공진 주파수로 커패시턴스가 안정적이었다. Meander Line은 RCC, 병렬 전송선로 간격-400um, 병렬 전송선로 길이-500um, 1층 설계 시, 인덕턴스-1.60nH, 자가 공진주파수-9.21GHz 특성이 가장 우수하고, Radial Stub는 RCC, $60^{\circ}$, 1층 설계 시, 커패시턴스-0.62pF, 자가 공진주파수-9.06GHz의 특성이 나타났고, T Stub는 RCC, Stub 길이-600um, Stub 너비-150um, 1층 설계 시, 커패시턴스 -0.38pF, 자가 공진주파수-10GHz이상으로 우수한 특성을 나타냈다.

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The Microstructure and Coarsening Behavior of Cr2O3 Dispersoid in ODS Cu Produced by Reactive Milling (반응성 밀링에 의해 제조된 Cr2O3 분산강화형 Cu 합금의 미세조직과 입자조대화)

  • Park, Eun-Bum;Hwang, Seung-Joon
    • Journal of the Korean Society for Heat Treatment
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    • v.31 no.4
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    • pp.171-179
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    • 2018
  • Copper powder dispersed with 4 vol.% of $Cr_2O_3$ was successfully produced by a simple milling at 210 K with a mixture of $Cu_2O$, Cu and Cr elemental powders, followed by Hot Pressing (HP) at 1123 K and 50 MPa for 2h to consolidate the milled powder. The microstructure of the HPed material was characterized by standard metallographic techniques such as XRD (X-ray Diffraction), TEM and STEM-EDS. The results of STEMEDS analysis showed that the HPed materials comprised a mixture of nanocrystalline Cu matrix and $Cr_2O_3$ dispersoid with a homogeneous bimodal size distribution. The mechanical properties of the HPed materials were characterized by micro Vickers hardness test at room temperature. The thermodynamic considerations on the heat of formation, the incubation time to ignite MSR (Mechanically induced Self-sustaining Reaction), and the adiabatic temperature for the heat of displacement reaction between the oxide-metal are made for the delayed formation of $Cr_2O_3$ dispersoid in terms of MSR suppression. The results of TEM observation and hardness test indicated that the relatively large dispersoids in the HPed materials are attributed to the significant coarsening for the high temperature consolidation; this leads to the low Vickers hardness value. Based on the thermodynamic calculation for the operating processes with a limited number of parameters, the formation kinetics and coarsening of the $Cr_2O_3$ dispersoid are discussed.