• Title/Summary/Keyword: Coordinated Control

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Bone regeneration and graft material resorption in extraction sockets grafted with bioactive silica-calcium phosphate composite (SCPC) versus non-grafted sockets: clinical, radiographic, and histological findings

  • Adel-Khattab, Doaa;Afifi, Nermeen S.;el Sadat, Shaimaa M. Abu;Aboul-Fotouh, Mona N.;Tarek, Karim;Horowitz, Robert A.
    • Journal of Periodontal and Implant Science
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    • v.50 no.6
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    • pp.418-434
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    • 2020
  • Purpose: The purpose of the present study was to evaluate the effect of silica-calcium phosphate composite (SCPC) granules on bone regeneration in extraction sockets. Methods: Ten patients were selected for a split-model study. In each patient, bone healing in SCPC-grafted and control ungrafted sockets was analyzed through clinical, radiographic, histomorphometric, and immunohistochemical assessments 6 months postoperatively. Results: A radiographic assessment using cone-beam computed tomography showed minimal ridge dimension changes in SCPC-grafted sockets, with 0.39 mm and 1.79 mm decreases in height and width, respectively. Core bone biopsy samples were obtained 6 months post-extraction during implant placement and analyzed. The average percent areas occupied by mature bone, woven bone, and remnant particles in the SCPC-grafted sockets were 41.3%±12%, 20.1%±9.5%, and 5.3%±4.4%, respectively. The percent areas of mature bone and woven bone formed in the control ungrafted sockets at the same time point were 31%±14% and 24.1%±9.4%, respectively. Histochemical and immunohistochemical analyses showed dense mineralized bundles of type I collagen with high osteopontin expression intensity in the grafted sockets. The newly formed bone was well vascularized, with numerous active osteoblasts, Haversian systems, and osteocytes indicating maturation. In contrast, the new bone in the control ungrafted sockets was immature, rich in type III collagen, and had a low osteocyte density. Conclusions: The resorption of SCPC granules in 6 months was coordinated with better new bone formation than was observed in untreated sockets. SCPC is a resorbable bone graft material that enhances bone formation and maturation through its stimulatory effect on bone cell function.

The Literature Review on the Relation between the Modulation of Arousal and the Suck/Swallow/Breathe(SSB) Synchrony (각성조절과 빨기/삼키기/숨쉬기의 조화(Suck/Swallow/Breathe Synchrony)와의 연관성에 관한 고찰)

  • Kim, In-Sun;Lee, Ji-Young;Hwang, Jee-Young
    • The Journal of Korean Academy of Sensory Integration
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    • v.1 no.1
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    • pp.61-72
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    • 2003
  • The suck/swallow/breathe(SSB) synchrony, serving as the earlist primary motor mechanism, is the rhythmical, coordinated pattern of sucking, swallowing and breathing. The development of an intact SSB is an important precursor for further sensorimotor and cognitive development including speech and language development, state regulation, postural control, feeding, eye/hand coordination and social/emotional development. Arousal means a neurological mechanism for preparing one's body to orienting stimulus. Its levels are regulated with an interaction of the reticular formation, the limbic system, the hypothalamus and the autonomic nervous system. General strategies such as blowing, sucking, chewing, munching and licking to effectively modulate arousal state are related to SSB. The SSB synchrony is an important treatment principle for children with sensory integration disorder and problems with the modulation of arousal. The purpose of this article is to review concepts of SSB synchrony and the underlying relation between the modulation of arousal and SSB synchrony.

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Application of Cost-Volume-Profit Analysis in Decision-Making by Public Universities in Vietnam

  • LE, Oanh Thi Tu;TRAN, Phong Thi Thu;TRAN, Thuan Van;NGUYEN, Cong Van
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.6
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    • pp.305-316
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    • 2020
  • This paper aims to examine the application of cost-volume-profit (CVP) analysis by public universities in Vietnam. In the context where Vietnam is gradually transferring financial autonomy to public universities, the conduct of a CVP analysis in relation to these public universities is particularly urgent. Research samples were collected in 2018 and 2019 by surveying Vietnamese public universities. After collection, the data is synthesized by excel file, conformity check, data cleansing and data analysis on SPSS software by tools such as Frequency statistics, price statistics, and means. The results show that: (1) universities used the CVP analysis in decision-making, (2) information related to the CVP analysis used for decision-making by administrators remained simplistic and lacked cost-control details, and (3) the application of the CVP analysis by university administrators for decision-making was neither comprehensive nor coordinated. The findings also show that, given the current conditions in Vietnam, increasing the governance in public universities is essential, as is contributing to reducing costs, increasing universities'income, providing the best service to students, and improving the quality of training. The study calls for the flexible application of the CVP analysis, which will provide information to help managers at Vietnamese public universities make the best decisions.

A Study on the Formation of Leader-Member's Interpersonal Trust Relationship and Member's Task Behavior (상사-부하간의 대인적 신뢰관계의 형성과 영향에 관한 연구)

  • 손기영
    • Journal of the Korea Society of Computer and Information
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    • v.4 no.1
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    • pp.92-98
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    • 1999
  • Interpersonal trust is the mutual "faithfulness" on which all social relationship ultimately depend and applicable to the relations among people rather than to their psychological states taken individually. Recent development in the organizational sciences reflect the importance of interpersonal trust relationships for sustaining individual and organizational effectiveness, researchers have recongnized trust's influence on coordination and control at both institutional and interpersonal levels of organization. Because economic action is embeded within networks of social relationships. researchers have argued that efficiency within complex systems of coordinated action is only possible when interdependent actors work together effectively. Thus, for managers and professionals in organizations, developing and maintaining trust relationship is especially import. The purpose of the present study is to investigate the mechanism of interpersonal trust in the organization. Especially, the major concern of this study is to verify role of interpersonal trust in the member's task behaviork behavior

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A Simulation-based Heuristic Algorithm for Determining a Periodic Order Policy at the Supply Chain: A Service Measure Perspective (공급사슬 내의 재고관리를 위한 모의실험에 기초한 발견적 기법: 봉사척도 관점)

  • Park, Chang-Kyu
    • IE interfaces
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    • v.13 no.3
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    • pp.424-430
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    • 2000
  • Supply chain management (SCM) is an area that has recently received a great deal of attention in the business community. While SCM is relatively new, the idea of coordinated planning is not. During the last decades, many researchers have investigated multi-stage inventory problems. However, only a few papers address the problem of cost-optimal coordination of multi-stage inventory control with respect to service measures. Even published approaches have a shortcoming in dealing with a delivery lead time consisted of a shipping time and a waiting time. Assumed that there is no waiting time, or that the delivery lead time is implicitly compounded of a shipping time and a waiting time, the problem is often simplified into a multi-stage buffer allocation and a single-stage stochastic buffer sizing problem at all installations. This paper presents a simulation-based heuristic algorithm and a comparison with others for the problem that cannot be decomposed into a multi-stage buffer allocation and a single-stage stochastic buffer sizing problem because the waiting time ties together all stages. The comparison shows that the simulation-based heuristic algorithm performs better than other approaches in saving average inventory cost for both Poisson and Normal demands.

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Coordination Under Price Protection, Mid/End Life Returns, and Quantity Discount for a Three-Level Supply Chain (가격보호 정책, 반품 정책과 물량할인 정책을 사용한 3단계 공급사슬의 협력방안)

  • Lee, Chang-Hwan
    • Journal of the Korean Operations Research and Management Science Society
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    • v.30 no.3
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    • pp.17-39
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    • 2005
  • The coordination of a three-level supply chain consisting of a supplier, a retailer, and a discount outlet (DCO) is studied here. We assume that the product is sold in two consecutive periods a Normal Sales Period (NSP) and a subsequent Clearance Salvage Period (CSP). A benchmark case is studied Initially in which the supply chain is coordinated by a s1n91e agent. Thus, the supplier the retailer, and the discount outlet design a common system that allows centralized decision making about stocking quantities, markdown time schedules, and policies on disposing of leftovers to deliver the greatest possible expected supply chain profit. Next, we consider a decentralized supply chain. Here, decisions are made without coordination. The objective is to maximize an individual party's expected profits. The focus of the study is on the following questions: what factors make the coordination an effective approach for the supply chain? How do we coordinate the supply chain so as to maximize the supply chain Joint expected profit? These and other related study issues are explored in this paper.

Toward Transparent Virtual Coupling for Haptic Interaction during Contact Tasks (컨택트 작업 시 햅틱 인터렉션의 투명성 향상을 위한 Virtual Coupling 기법의 설계)

  • Kim, Myungsin;Lee, Dongjun
    • The Journal of Korea Robotics Society
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    • v.8 no.3
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    • pp.186-196
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    • 2013
  • Since its introduction (e.g., [4, 6]), virtual coupling technique has been de facto way to connect a haptic device with a virtual proxy for haptic rendering and control. However, because of the single dependence on spring-damper feedback action, this virtual coupling suffers from the degraded transparency particularly during contact tasks when large device/proxy-forces are involved. In this paper, we propose a novel virtual coupling technique, which, by utilizing passive decomposition, reduces device-proxy position deviation even during the contact tasks while also scaling down (or up) the apparent inertia of the coordinated device-proxy. By doing so, we can significantly improve transparency between multiple degree of freedom (possibly nonlinear) haptic device and virtual proxy. In other to use passive decomposition, disturbance observer of [3] is adopted to estimate human force with some dead-zone modification to avoid "winding-up" force estimation in the presence of device torque saturation. Some preliminary experimental results are also given to illustrate efficacy of the proposed technique.

Building Corporate Information Governance to Prepare in Case of Litigation - Practical Implications of Sedona Conference Principles of Information Governance - (기업 소송에 대비한 정보거버넌스의 구축 방안 - 세도나 정보거버넌스 원칙을 중심으로 -)

  • Seol, Moon-Won
    • Journal of Korean Library and Information Science Society
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    • v.46 no.4
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    • pp.325-354
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    • 2015
  • Corporate information has great value, but also poses great risk. Information governance is an organization's coordinated, inter-disciplinary approach to satisfying information compliance requirements and managing information risks while optimizing information value. This study aims to suggest the directions of implementing information governance in business firms based on analyses of Sedona Conference Principles of Information Governance. After analysing and reformulating the principles into control standards, and they are investigated and interpreted in terms of practicing information governance.

A Smart Framework for Mobile Botnet Detection Using Static Analysis

  • Anwar, Shahid;Zolkipli, Mohamad Fadli;Mezhuyev, Vitaliy;Inayat, Zakira
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.14 no.6
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    • pp.2591-2611
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    • 2020
  • Botnets have become one of the most significant threats to Internet-connected smartphones. A botnet is a combination of infected devices communicating through a command server under the control of botmaster for malicious purposes. Nowadays, the number and variety of botnets attacks have increased drastically, especially on the Android platform. Severe network disruptions through massive coordinated attacks result in large financial and ethical losses. The increase in the number of botnet attacks brings the challenges for detection of harmful software. This study proposes a smart framework for mobile botnet detection using static analysis. This technique combines permissions, activities, broadcast receivers, background services, API and uses the machine-learning algorithm to detect mobile botnets applications. The prototype was implemented and used to validate the performance, accuracy, and scalability of the proposed framework by evaluating 3000 android applications. The obtained results show the proposed framework obtained 98.20% accuracy with a low 0.1140 false-positive rate.

Modulation of a Fungal Signaling by Hypovirus

  • Kim, Dae-Hyuk
    • The Plant Pathology Journal
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    • v.19 no.1
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    • pp.30-33
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    • 2003
  • The chestnut blight fungus, Cryphonectria parasitica, and its hypovirus aye a useful model system in the study of the mechanisms of hypoviral infection and its consequences, such as a biological control of fungal pathogens. Strains containing the double-stranded (ds) RNA viruses Cryphonectria hypovirus 1 show characteristic symptoms of hypovirulence and display hypovirulence-associated changes, such as reduced pigmentation, sporulation, laccase production, and oxalate accumulation. Interestingly, symptoms caused by hypoviral infection appear to be the result of aberrant expression of a number of specific genes in the hypovirulent strain. Several viral regulated fungal genes are identified as cutinase gene, Lac1, which encodes an extracellular laccase, Crp, which encodes an abundant tissue-specific cell-surface hydrophobin that mediates physical strength, and Mf2/1 and Mf2/2, which encode pheromone genes involved in poor sporulation in the presence of hypo-virus. Since the phenotypic changes in the fungal host are pleiotropic, although coordinated and specific, it has been suggested that the hypovirus disturbs one or several regulatory pathways (Nuss,1996). Accordingly, several studies have shown the implementation of a signal transduction pathway during viral symptom development. Although further studies are required, hypovirulence and its associated symptom development due to the hypoviral regulation of a fungal hetero-trimeric G-protein have been suggested. In addition, recent studies have shown the presence of a novel protein kinase gene cppk1 and its transcriptional upregulation by hypovirus. In this review, the presence of important components in signal transduction pathway, their putative biological function, and viral-specific regulation will be addressed.