• Journal of mucopolysaccharidosis and rare diseases
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• 제5권1호
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• pp.29-33
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• 2021

Prader-Willi Syndrome (PWS) is a neurodevelopmental genomic imprinting disorder involving a lack of gene expression from the paternal chromosome 15q11-q13 region. This is typically due to paternal 15q11-q13 deletions (in approximately 60% of cases), maternal uniparental disomy 15, or when both 15s are from the mother (about 35% of cases). An imprinting center controls the expression of imprinted genes in the chromosome 15q11-q13 region. PWS is a neurodevelopmental disorder characterized by mental retardation and distinct physical, behavioral, and psychiatric features. Characteristic behavioral disturbances in PWS include excessive interest in food, skin picking, difficulty with a change in routine, temper tantrums, obsessive and compulsive behaviors, and mood fluctuations. Individuals with PWS typically have intellectual disabilities (borderline to mild/moderate mental retardation) and exhibit a higher overall level of behavior disturbances compared to individuals with similar intellectual disabilities. This condition severely limits social adaptations and quality of life. Different factors have been linked to the intensity and form of these behavioral disturbances, but there is no consensus regarding the cause. Consequently, there is still controversy surrounding management strategies and there is a need for new data. PWS is a multisystem disorder. Family members, caregivers, physicians, dieticians, and speech-language pathologists all play an important role in the management and treatment of symptoms in an individual with PWS. Here we analyze behavioral problems in children and adults with PWS by age and review appropriate management and treatment strategies for these symptoms.

• Journal of Yeungnam Medical Science
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• 제38권1호
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• pp.19-26
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• 2021

Adhesive capsulitis of the shoulder joint is a common disease characterized by pain at the insertional area of the deltoid muscle and decreased range of motion. The pathophysiological process involves fibrous inflammation of the capsule and intraarticular adhesion of synovial folds leading to capsular thickening and contracture. Regarding the multidirectional limitation of motion, a limitation in external rotation is especially prominent, which is related to not only global fibrosis but also to a localized tightness of the anterior capsule. Ultrasound and magnetic resonance imaging studies can be applied to rule out other structural lesions in the diagnosis of adhesive capsulitis. Hydraulic distension of the shoulder joint capsule provides pain relief and an immediate improvement in range of motion by directly expanding the capsule along with the infusion of steroids. However, the optimal technique for hydraulic distension is still a matter of controversy, with regards to the infusion volume and rupture of the capsule. By monitoring the real-time pressure-volume profile during hydraulic distension, the largest possible fluid volume can be infused without rupturing the capsule. The improvement in clinical outcomes is shown to be greater in capsule-preserved hydraulic distension than in capsule-ruptured distension. Moreover, repeated distension is possible, which provides additional clinical improvement. Capsule-preserved hydraulic distension with maximal volume is suggested to be an efficacious treatment option for persistent adhesive capsulitis.

• Journal of Korean Neurosurgical Society
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• 제65권2호
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• pp.173-179
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• 2022

Disabilities can emerge due to traumatic spinal fractures. In terms of sacrococcygeal spine, because of its unique anatomic structure with minimal movement, the possibility for it to have a disability is relatively low. In Korea, unlike most disability criteria, private insurance companies acknowledge angular deformities caused by vertebral fractures as disabilities according to their degree, so there were several cases where patients required compensation, arguing angular deformity caused by sacrococcygeal fracture, which in some cases led to legal conflicts. Except the Act Welfare of Persons with Disabilities which recognizes only severe angular deformity affecting internal organs as disability and the industrial accident disability evaluation which does not recognize coccygeal fracture as disability but rarely recognizes sacral vertebra deformity equivalent to compressive deformation, there is little or no case where angular deformity is recognized as disability. Given the impairment evaluation standards in social insurance, McBride system, American Medical Association (AMA) guides, and newly proposed standards by the Korean Academy of Medical Sciences (KAMS), the most contentious point in the general terms and conditions of private insurance is spinal deformity. To overcome controversy over disability evaluation, the private insurance sector is now applying criteria for axial skeleton to sacrococcygeal vertebrae through revision of standards. Under these circumstances, it is fair to recognize sacrococcygeal fracture as impairment in terms of the pelvis only when the fracture leaves serious deformity and neurological symptoms with clear relevancy. Though it may not be easy to develop accurate disability evaluation standards, improvement is necessary to remove any irrationalities and make the standards as objective as possible.

• 한국환경과학회지
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• 제31권7호
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• pp.579-592
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• 2022

Much controversy has been generated over whether the ecological restoration project in Korea is faithful to the basic approach of ecological restoration compared to projects aimed at creating parks or green spaces. This study was aimed at understanding the level of awareness of practitioners in the planting design method, which is recognized as relatively important in landscape architecture and ecological restoration. The proficiency of practitioners in planting design techniques for ecological restoration projects was investigated and analyzed in seven areas: overall planting design awareness, plant species selection method, planting tree sizes, planting density, use of native species, vegetation climatic zone, soil environment, and weed control. There was no statistically significant difference between the group who thought they were experts in the field of ecological restoration and the group who thought they were experts in the field of parks and green spaces. Moreover, there was no statistically significant difference between the degree of work performance, that is, the group whose main industry was ecological restoration, the group that performed relatively more ecological restoration work, and the group that rarely performed it. Therefore, to apply desirable ecological restoration techniques in the future and to clearly differentiate between the approach in the field of parks and green spaces, the appropriate tree size or planting density selected in the ecological restoration planting design stage must be chosen. To this end, the awareness of expert groups must be improved and related laws, systems, and guidelines must be revised.

• 한국문헌정보학회지
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• 제56권3호
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• pp.291-312
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• 2022

본 연구는 도서관명의 변화 분석을 통해 도서관계의 주요한 변화를 밝히고자 하였다. 2015년부터 2020년까지 국가도서관통계시스템에 등록된 도서관명을 이용하여 변화의 유형과 특징을 분석하였다. 분석결과, 5년 동안의 도서관명 변화 과정 속에서 총 211건의 변화를 발견하였고 이들을 7가지 유형으로 구분하였다. 분석과정을 통해 도서관계에서의 운영주체 논란과 청소년서비스에 대한 관심 증가, 도서관 주제 특성화, 공모전을 통한 도서관명 결정 등이 주요한 특징으로 나타났다.

• International Journal of Advanced Culture Technology
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• 제10권4호
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• pp.117-125
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• 2022

Along with the uprising of sustainability issues in the field of business and management, firms increasingly strategize and mobilize resources towards sustainability related activities and processes much more than ever. Together with this phenomenon, the concept of corporate sustainability has been noticed much more by scholars and practitioners from diverse fields. However, differently with an expectation, it is undoubted that there is a small controversy when we treat the issues related to its definition, antecedents, consequences, processes and so on. Based on this kind of understanding, this study tries to suggest and advance a new approach to the corporate sustainability based on the premises of social capital theory for social relations, which explains the role of institutions, and norms that shape firms 'social interactions. Main argument is that firm's voluntary, progressive, and proactive activities for sustainability issues can be understood as the firm's social capital building processes. Though there are a little existing study dealing with this issue, this study has a difference with them by proposing social capital building issues based on firm's real activities. Finally, case analyses based on a new approach are suggested and the theoretical considerations with some limitations are explained.

• 한국IT서비스학회지
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• 제21권6호
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• pp.73-89
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• 2022

After COVID-19, the percentage of digital consumption has soared. Meanwhile, as the online platform market grows in size and digital commerce is activated, controversy over the "dark pattern" that induces consumers to do unintended things online continues. Dark patterns are deceptive design patterns that cause consumer rights and financial damage and can result in damaging fair market competition. As a result, the need to regulate dark patterns is raised not only by overseas regulators but also in Korea, and there are growing calls for strengthening consumer protection against dark patterns, with amendments to related laws being proposed by the National Assembly. On the other hand, there is no agreed definition of dark pattern from a normative point of view, and there is a concern that even legitimate advertising marketing activities of companies may be regulated, so a review of dark pattern regulatory measures is required. In this study, dark patterns were reviewed from a normative point of view and appropriate regulatory measures were analyzed. In particular, the problem of the dark pattern can be applied in a way that the market regulates and controls itself in consideration of the characteristics of the online platform. This study reviewed the possibility of self-regulation for dart patterns and proposed the role of each subject.

• Clinical and Experimental Pediatrics
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• 제65권1호
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• pp.21-28
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• 2022

Crohn disease (CD) is a multifactorial inflammatory disorder that can affect all segments of the gastrointestinal (GI) tract but typically involves the ileum and/or colon. To assess patient prognosis and choose appropriate treatment, it is necessary to accurately evaluate the factors influencing poor outcomes, including disease phenotype. Pediatric CD involving the upper GI (UGI) tract has become increasingly recognized with the introduction of routine upper endoscopy with biopsies for all patients and the increased availability of accurate small bowel evaluations. Most clinical manifestations are mild and nonspecific; however, UGI involvement should not be overlooked since it can cause serious complications. Although controversy persists about the definition of upper GI involvement, aphthoid ulcers, longitudinal ulcers, a bamboo joint-like appearance, stenosis, and fistula are endoscopic findings suggestive of CD. In addition, the primary histological findings, such as focally enhanced gastritis and noncaseating granulomas, are highly suggestive of CD. The association between UGI involvement and poor prognosis of CD remains controversial. However, the unstandardized definition and absence of a validated tool for evaluating disease severity complicate the objective assessment of UGI involvement in CD. Therefore, more prospective studies are needed to provide further insight into the standardized assessment of UGI involvement and long-term prognosis of CD. Our review summarizes the findings to date in the literature as well as UGI involvement in CD and its clinical implications.

• International Journal of Computer Science & Network Security
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• 제22권11호
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• pp.1-10
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• 2022

This study aims to build a model is capable of classifying the categories of hadith, according to the reliability of hadith' narrators (sahih, hassan, da'if, maudu) and according to what was attributed to the Prophet Muhammad (saying, doing, describing, reporting ) using the supervised learning algorithms, with a view to discover a relationship between these classifications, based on the outputs of this model, which might be useful to avoid the controversy and useless debate on automatic classifications of hadith, using some of the statistical methods such as chi-square, information gain and association rules. The experimental results showed that there is a relation between these classifications, most of Sahih hadiths are belong to saying class, and most of maudu hadiths are belong to reporting class. Also the best classifier had given high accuracy was MultinomialNB, it achieved higher accuracy reached up to 0.9708 %, for his ability to process high dimensional problems and identifying the most important features that are relevant to target data in training stage. Followed by LinearSVC classifier, reached up to 0.9655, and finally, KNeighborsClassifier reached up to 0.9644.

• Journal of Information Technology Applications and Management
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• 제29권1호
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• pp.59-70
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• 2022

Recently, in platforms such as YouTube and Instagram, virtual characters resembling human life become the main characters, produce various contents, breathe with the public, and create the era of virtual humans. For example, existing game characters appear as virtual characters with unique AUs, or AI characters created by reflecting the public's preferences are actively communicating with the public through advertisements and SNS activities. As the consumption of video content through smart devices increases significantly in the post-corona era, virtual influencers are being used as all-round entertainers because there is little risk of personality controversy or production cost. there is a trend In this study, we investigated the characteristics of the case of being active as an influencer among the activities of a virtual character, and how the interactive aspect of the influencer appears by identifying the current situation through major cases. Combining this, based on the analysis of the influence of virtual influencers, the parts that producers should recognize are derived, and the differentiated characteristics of interactive virtual influencers are summarized. In addition, the difficulties of virtual influencers were investigated and problems were identified, and for the development of the content industry, a more favorable method for interaction was presented and suggestions were made to secure inner sincerity.