• 제목/요약/키워드: Controlled clinical trials, randomized

검색결과 783건 처리시간 0.023초

Acupuncture Treatment for Shoulder Impingement Syndrome: A Review of Randomized Controlled Trials

  • Park, Jae Eun;Kim, Woo Young;Lee, Soo Jin;Oh, Da Yoon;Lee, Min Cheol;Jeon, Myung Kyu;Kim, Hyeon Jin;Ahn, Jae Young;Yang, Su Hyeon;Choi, Yun Young;Shin, Na Young;Nam, Hye Jin
    • Journal of Acupuncture Research
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    • 제38권3호
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    • pp.175-182
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    • 2021
  • To evaluate the effectiveness of acupuncture treatment for shoulder impingement syndrome (SIS) a literature review was conducted of randomized controlled trials (RCTs) where acupuncture was used as an intervention for patients diagnosed with SIS. Relevant clinical studies (N = 181) were retrieved from several databases based on the inclusion/exclusion criteria, and the interventions and results were analyzed. Six RCTs were selected to review based on the inclusion and exclusion criteria. In all 6 studies, the acupuncture treatment group showed significant positive changes in indicators evaluating pain, disability, and quality of life. A significant decrease in the evaluation indicators (Shoulder Pain and Disability Index, numeric rating scale, Visual Analogue Scale, Constant Murley Shoulder Assessment Score, patient's global assessment, and doctor's global assessment) and a significant increase in the questionnaire scores (UCLA, AL-score, EuroQol 5 Dimension Self-Report Questionnaire, and disabilities of the arm, shoulder, and hand) were observed. In addition, 1 study showed similar improvements in pain and quality of life measures in the acupuncture group and corticosteroid injection group. No major side effects were reported. Acupuncture may be an effective and safe treatment for SIS however, further RCTs are required.

국내 치매환자의 인지기능 향상을 위한 중재의 효과: 무작위 대조군 실험연구의 체계적 문헌고찰 (The Effect of Intervention on Improving Cognitive Function of Patients with Dementia in Korea : A Systematic Review of Randomized Controlled Trials)

  • 정재훈
    • 산업융합연구
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    • 제19권5호
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    • pp.91-102
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    • 2021
  • 본 연구는 국내 치매환자의 인지기능 향상을 위한 중재에 대한 특성과 효과를 분석하기 위해 무작위 대조군 실험연구에 대한 체계적 고찰을 시행하였다. 5개의 검색 데이터베이스를 사용하여 2010년 1월부터 2021년 6월까지 발표된 연구를 분석하였다. 총 1,104편의 연구가 검색되어 총 27편의 연구를 최종 분석하였다. 문헌의 질 평가는 Risk of bias(RoB)를 사용하였다. 인지기능 평가도구는 Mini-Mental Status Examination(MMSE)이 가장 많이 사용되었다. 인지기능 중재는 운동치료, 미술치료, 인지자극, 회상치료, 음악치료, 복합인지재활, 가상현실, 원예치료, 컴퓨터기반 인지훈련, 의도적 다감각자극, 미용치료, 요리활동, 한국적 익숙함이 적용되었다. 운동치료 2편, 가상현실 1편, 미용치료 1편을 제외하고 모든 연구에서 인지기능에 유의한 향상이 나타났다. 본 연구는 국내 치매환자의 인지기능에 대한 중재를 계획하고 실행하는데 임상적 근거를 제시하였다. 향후에는 연구방법의 질적 향상으로 체계적이고 치매의 특성에 맞는 다양한 중재 연구가 이루어져야 할 것이다.

국내에서 수행된 건강인 대상 침 관련 무작위 대조 임상연구에 대한 체계적 문헌 고찰 (Randomized Controlled Trials of Acupuncture for Healthy Volunteers in Korea: A Systematic Review)

  • 사공혜선;김현태;허인;신병철
    • 한방재활의학과학회지
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    • 제31권1호
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    • pp.137-147
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    • 2021
  • Objectives Domestic acupuncture research is being actively conducted in various fields. The aim of this study is to systematically analyze the current acupuncture randomized controlled trials (RCTs) conducted on healthy volunteers. Methods We searched RCTs by the search terms of (acupuncture & random & healthy) in 10 electronic databases and related journals. Then, we analyzed the characteristics and assessed the risk of bias by Cochrane tool. Results Finally, 49 acupuncture RCTs on health volunteers were included in our analysis. The purpose of research could be classified into five major categories: (1) checking the effects on physiological function, (2) comparing the effects of different acupuncture/acupuncture methods, (3) a study confirming improvement after inducing a specific condition, (4) a sham acupuncture study, and (5) a comparison of acupuncture sense. The Cochrane risk of bias was generally high, especially only 1 trial adopted allocation concealment (1/49, 2.0%) and 9 ones with assessor blinding (9/49, 18.4%). Conclusions Acupuncture RCTs in healthy subjects have confirmed various effects in various age/sex groups. However the research quality should be updated for future clinical research and to draw clear conclusion within rigorous methodology.

경도인지장애 노인의 우울증상을 위한 비약물적 중재 효과: 무작위 대조군 실험연구의 체계적 문헌고찰 (The Effect of Non-Pharmacological Intervention on Depressive Symptom in Elderly with Mild Cognitive Impairment : A Systematic Review of Randomized Controlled Trials)

  • 정재훈
    • 산업융합연구
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    • 제20권10호
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    • pp.39-49
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    • 2022
  • 본 연구는 국외 경도인지장애 노인의 우울증상을 위한 비약물적 중재에 대한 특성과 효과를 분석하기 위해 무작위 대조군 실험연구에 대한 체계적 고찰을 시행하였다. 3개의 검색 데이터베이스를 사용하여 2011년 1월부터 2021년 7월까지 출간된 문헌을 분석하였다. 총 1,455편의 문헌이 검색되어 총 11편의 문헌을 최종 분석하였다. 문헌의 질 평가는 Risk of bias(RoB)를 사용하였다. 우울증상 평가도구는 Geriatric Depression Scale(GDS)이 가장 많이 사용되었다. 분석된 문헌에서 사용된 중재는 요가, 심리사회적 중재, 인지훈련, 건강교육, 다중요소 중재, 게임훈련, 유산소/심폐물리치료, 미술치료, 음악회상 활동, 기억특이성 훈련, 인지자극, 수면교육이 적용되었다. 그 중 요가, 다중요소 중재, 게임훈련이 우울증상 개선에 효과적이었다. 본 연구는 경도인지장애 노인의 우울증상에 대한 중재계획 및 실행에서 임상적 근거를 제시하였다.

Analysis of Clinical Research Trends for Thread Embedding Acupuncture of Cervical Radiculopathy

  • Eun Sil, Heo;Hyun-Jong, Lee;Jung Hee, Lee;Sang Ha, Woo;Yun Kyu, Lee;Seong Hun, Choi;Jae Soo, Kim
    • Journal of Acupuncture Research
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    • 제39권4호
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    • pp.283-296
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    • 2022
  • In this study, the evidence of thread embedding acupuncture (TEA) in treating cervical radiculopathy in randomized controlled trials was investigated. We searched 16 databases up to August 22, 2022. Of the 2,644 studies retrieved, 22 randomized controlled trials (2,483 participants) were selected. Quality assessments were performed using Cochrane's risk-of-bias tool and RevMan 5.4 software. Outcome measures in the included studies typically showed TEA had a significant therapeutic effect compared with simple acupuncture and other remedies, and TEA was better than sham TEA. Catgut and polydioxanone had no difference in effectiveness, however, catgut was considered to be less safe. TEA was shown to be more therapeutic when inserted deeper into the skin. Ultrasound guided TEA was more effective and safer than conventional TEA, and using a flat blade needle was better than conventional needles for TEA. No serious adverse events were reported from using TEA, and only a few mild side effects were observed. However, the limited number and heterogeneity of the included studies, together with the unclear methodological quality, indicate that higher-quality studies need to be conducted to determine the effectiveness and safety of TEA for cervical radiculopathy.

대한한의학회지 및 대한한의학회 산하 정회원 학회의 학술진흥재단 등재지에 대한 비염 임상연구의 체계적 고찰 (A Systematic Review from the Journals under the Korean Oriental Medical Society)

  • 이규선;박동희;김계은;방지현;김재환;최준용;정희재;정승기
    • 대한한의학회지
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    • 제31권5호
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    • pp.1-11
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    • 2010
  • Objectives: This study aimed to evaluate any clinical studies regarding rhinitis published by the Korean Oriental Medical Society and its sub-societies for future rigorous clinical research. Methods: Every article relevant to rhinitis was initially obtained from journals of the Korean Oriental Medical Society and its sub-societies by electronic search at journal web sites or manual searches. Journals were limited to those registered with the Korea Research Foundation. From initial findings, two independent reviewers selected clinical articles and these articles were further analyzed separately by predefined criteria according to prospective and retrospective studies. For prospective studies, quality assessment was also conducted. Results: From 36 initially obtained articles, 17 were finally analyzed. 2 articles were randomized controlled studies, 6 articles were prospective whereas 9 were retrospective. In the prospective articles, there were no randomized controlled trials and the other non-randomized studies had no control group with several problems of quality regarding pre-calculated study size and unbiased assessment. None of the retrospective studies described rhinitis diagnosis objectively and outcome measures were either non-relevant to rhinitis or non-validated. Conclusions: Further well-designed randomized controlled studies for rhinitis are mandatory and more rigorous non-randomized controlled studies should be conducted.

Pragmatic Clinical Studies: An Emerging Clinical Research Discipline for Improving Evidence-Based Practice of Cardiovascular Diseases in Asia

  • Dong Zhao;Chen Yao
    • Korean Circulation Journal
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    • 제52권6호
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    • pp.401-413
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    • 2022
  • Pragmatic clinical studies, an emerging clinical research discipline, include a wide range of studies that are largely embedded with routine clinical practice and aim to evaluate the comparative effectiveness and safety of different clinical intervention strategies. Increased availability and quality of electronic medical/health records drives the development of pragmatic clinical studies. In this review, we describe evolution of the conceptual framework of pragmatic clinical studies and share perspectives on the importance of pragmatic clinical studies in evidence-based practice for cardiovascular diseases, as a complement to conventional randomized controlled trials. We also highlight specific needs of pragmatic clinical studies in improving evidence-based practice for cardiovascular disease in Asian countries. The main challenges of pragmatic clinical studies are discussed briefly in this review.

지루 피부염 (Seborrheic Dermatitis)의 외세요법에 대한 최신 연구 동향 - 중국 무작위 대조군 임상연구를 중심으로 - (A Review of Clinical Studies for External Washing on Seborrheic Dermatitis - Focused on Chinese Randomized Controlled Trials -)

  • 류의성;이민영;장수비;최일신;김기봉;천진홍
    • 대한한방소아과학회지
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    • 제37권2호
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    • pp.28-42
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    • 2023
  • Objective This study aimed to analyze the efficacy and safety of external washing therapy for seborrheic dermatitis based on randomized controlled clinical studies in China. Methods We used the China National Knowledge Infrastructure (CNKI) as a data resource and conducted a search using the following key words: "Seborrheic Dermatitis" and "外洗" Seven randomized controlled clinical studies were identified and analyzed in this study. Results 1. The external washing treatment group showed significant changes in total efficiency, relapse rates, Quality of life, and Hamilton depression rating scale, compared with the control group. 2. The most commonly used herbal medicines were Sophorae Radix (苦蔘), Thujae Orientalis Folium (側柏葉), Impatiens balsamina L. (透骨草), Phellodendri Cortex (黃柏), and Stemonae Radix (百部根). Conclusions The results indicate that external washing treatment is effective for patients with seborrheic dermatitis. Futher research on external washing treatment of seborrheic dermatitis in the future may be useful.

소아 비출혈의 한약 치료에 대한 임상 연구 동향 - 2000년대 이후 발표된 중국 RCT 연구를 중심으로 - (Review of Clinical Studies of Herbal Medicine Treatment for Pediatric Epistaxis - Focused on Chinese Randomized Controlled Trials after 2000s -)

  • 박용석;신혜진;이지홍;장규태
    • 대한한방소아과학회지
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    • 제34권1호
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    • pp.48-60
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    • 2020
  • Objectives The purpose of this study is to investigate recent clinical studies on the effect of herbal medicine for pediatric epistaxis in China, and to seek better methods to treat and study for pediatric epistaxis in Republic of Korea. Methods We searched the clinical studies from the China Academic Journal (CAJ) in China National Knowledge Infrastructure (CNKI) by key words 鼻出血', '鼻衄', '衄血', '中藥', '中医藥', '本草', '湯', '丸', '散', '方','顆粒', '膠囊', '自擬', '外用', '膏 from January 2000 to November 2019. We analyzed the literature in regards to the treatment methods and results. Results Among the 1141 searched studies, 12 randomized controlled trials were selected and analyzed. In most of the studies, the effectiveness of herbal medicine on pediatric epistaxis was significantly high. The most commonly used herbs for oral administration were Rehmanniae Radix (生地黃), Scutellariae Radix (黃芩), Imperatae Rhizoma (白茅根). The most commonly used herbs for external applications were Notoginseng Radix (三七), Bletilla striata (白芨), Crinis Carbonisatus (血餘炭). Conclusions Herbal medicine treatment can help improve pediatric epistaxis. Additional studies need to be performed to solidify these findings. In addition to that, unified criteria for treatment of pediatric epistaxis should be established in Republic of Korea.

불안장애에 대한 침 치료 임상 연구의 체계적 고찰 (A Systematic Review of Clinical Studies on the Effects of Acupuncture on Anxiety Disorders)

  • 김경옥;김천중;서상일;김남열;김근우
    • 동의신경정신과학회지
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    • 제28권3호
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    • pp.249-262
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    • 2017
  • Objectives: The aim of this study was to investigate the clinical studies which focus on acupuncture's effect on anxiety disorder. Methods: We selected clinical studies through six databases. We then examined the characteristics of the selected studies and conducted an assessment for Risk of Bias (ROB). Results: Seventeen randomized-controlled trials were selected to determine the effects of acupuncture on anxiety disorders. We found that the risk of bias in most studies was unclear. The intervention of 7 seventeen randomized-controlled trials (RCT) was basic acupuncture, 8 RCT involved electric acupuncture, 2 RCT consisted of acupuncture and Moxibustion. Four of the 7 basic acupuncture RCTs and 5 of the 8 electric acupuncture RCTs had a significant effect on anxiety factors for anxiety disorders. Conclusions: Acupuncture treatment for anxiety disorders was found to be effective compared to the controls, or there was no difference in effectiveness compared to the controls. However, the quality of the included studies was low, and there only were a small number of studies. Therefore, well-designed studies and a greater number of the studies are needed.