• Journal of Preventive Medicine and Public Health
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• 제27권4호
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• pp.711-734
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• 1994

Among chemical agents in herbicides, dioxin (2, 3, 7, 8-tetrachloro dibenzo-$\rho$-dioxin : TCDD), a chemical contaminant in herbicides sprayed during the Vietnam War has been known to be the major agent causing toxic effects. Approximately 320,000 korean soldiers participated the Vietnam War from 1964 to 1974. Although the potential hazards of the herbicides among Korean veterans exposed were implicated, the problem had not been a public issue until 1991 when Korean veterans were informed U.S. companies, the herbicides manufacturer payed fund, from which a trust fund for New Zealand and Australian Class members were established in 1985. After a series of appeals and demonstration by the Korean Veterans demanding medical care and compensation for their serious health damages, a bill of medical care and compensation for herbicides victims was promulgated in March 1993 and become effective from May 1993, This study was carried out with two major objectives : the first to understand the health problems caused from the herbicides by reviewing literatures published, and the second to examine the nature and extent of health impacts among Korean veterans exposed and to develop valid study methods for the major study by interviewing and reviewing records on a part of veterans (638 persons) registered and completed medical examination in Seoul Veterans Administration Hospital from June to October 1993. The results obtained are as followings: 1. The literature review of 107 papers revealed that 1) Dioxin is teratogenic, carcinogenic and affects almost all organs including nervous, endocrine, and reproductive systems in animal experiments. 2) The diseases showing evidence of causal association were Hodgkin's disease, non-Hodgkin's disease, lung cancer, lymphoma, soft tissue sarcoma, chloroacne and polyneuropathy when judged on the basis of consistency in study results and biological plausibility. 2. Interview and medical record review study on 638 veterans, though limited validity owing to lack of control group, crude estimates of dioxin exposure levels (no biomarkers measurable), and uncertainty of diagnosis, showed that: 1) Most of the study subject's were in their 40's of age and had been dispatched to Vietnam during the period from $1965{\sim}1970$ around one year. 2) Most frequently complained symptoms in medical examination were motor weakness (32%), sensory abnormalities in extremities (23%), skin diseases (22%), and pain in extremities (20%) whereas in Interview they were more frequent in order of skin problem (44%), motor weakness (38%), sensory abnormalities and pain in extremities(17% and 19% each). Kappa indices on the same category of complaints between two sources of information were variable and relatively low. 3) On medical examination, only a part of the 638 subjects had initial impression (442 pts) and final diagnosis (218 pts) suggesting decision making on diagnosis appeared to be difficult even with all available modern medical technologies: in initial impression disorders from peripheral and central neuropathy were predominant whereas in final diagnosis various types of skin disorder were most frequent 4) When dose-response relationship between several conditions (from questionnaire) and arbitrary exposure scores were examined by CMH linear trend test, spontaneous abortion, sexual problems and health problem of offsprings showed statistically significant linear trends. However, pregnancy, accident and suicidal attempts did not show any relationship in this study capacity. 5) Among complaints, psychosis and neurosis (anxiety, phobia) in interview study, and memory disorder and psychosis in medical record study revealed linear trend. 6) Skin disorder was the only condition showing linear trend in initial impression and none in final diagnosis on medical examination. Even though objective to select out dioxin-related disease or group of diseases from this study was not achieved the research experiences provided firm basis for developing various methodological approaches. 3. From this preliminary study we concluded that a larger scale major epidemiologic study on health impacts of herbicides among Korean veterans exposed is not only Indispensible but also well designed study with more valid exposure information and diagnosis may be able to establish causal relationship between certain groups of diseases and exposure to the herbicides among Korean veterans.

• Asia pacific journal of information systems
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• 제17권4호
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• pp.61-95
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• 2007

Small-and-medium sized enterprises(SMEs) represent quite a large proportion of the industry as a whole in terms of the number of enterprises or employees. However researches on information system so far have focused on large companies, probably because SMEs were not so active in introducing information systems as larger enterprises. SMEs are now increasingly bringing in information systems such as ERP(Enterprise Resource Planning Systems) and some of the companies already entered the stage of ongoing use. Accordingly, researches should deal with the use of information systems by SME s operating under different conditions from large companies. This study examined factors and mechanism inducing faithful appropriation of information systems, in particular integrative systems such as ERP, in view of individuals` active feedback-seeking behavior. There are three factors expected to affect end users` feedback-seeking behavior for faithful appropriation of information systems. They are management support, peer IT champ support, and IT staff support. The main focus of the study is on how these factors affect feedback-seeking behavior and whether the feedback-seeking behavior plays the role of mediator for realizing faithful appropriation of information systems by end users. To examine the research model and the hypotheses, this study employed an empirical method based on a field survey. The survey used measurements mostly employed and verified by previous researches, while some of the measurements had gone through minor modifications for the purpose of the study. The survey respondents are individual employees of SMEs that have been using ERP for one year or longer. To prevent common method bias, Task-Technology Fit items used as the control variable were made to be answered by different respondents. In total, 127 pairs of valid questionnaires were collected and used for the analysis. The PLS(Partial Least Squares) approach to structural equation modeling(PLS-Graph v.3.0) was used as our data analysis strategy because of its ability to model both formative and reflective latent constructs under small-and medium-size samples. The analysis shows Reliability, Construct Validity and Discriminant Validity are appropriate. The path analysis results are as follows; first, the more there is peer IT champ support, the more the end user is likely to show feedback-seeking behavior(path-coefficient=0.230, t=2.28, p<0.05). In other words, if colleagues proficient in information system use recognize the importance of their help, pass on what they have found to be an effective way of using the system or correct others' misuse, ordinary end users will be able to seek feedback on the faithfulness of their appropriation of information system without hesitation, because they know the convenience of getting help. Second, management support encourages ordinary end users to seek more feedback(path-coefficient=0.271, t=3.06, p<0.01) by affecting the end users' perceived value of feedback(path-coefficient=0.401, t=6.01, p<0.01). Management support is far more influential than other factors that when the management of an SME well understands the benefit of ERP, promotes its faithful appropriation and pays attention to employees' satisfaction with the system, employees will make deliberate efforts for faithful appropriation of the system. However, the third factor, IT staff support was found not to be conducive to feedback-seeking behavior from end users(path-coefficient=0.174, t=1.83). This is partly attributable to the fundamental reason that there is little support for end users from IT staff in SMEs. Even when IT staff provides support, end users may find it less important than that from coworkers more familiar with the end users' job. Meanwhile, the more end users seek feedback and attempt to find ways of faithful appropriation of information systems, the more likely the users will be able to deploy the system according to the purpose the system was originally meant for(path-coefficient=0.35, t=2.88, p<0.01). Finally, the mediation effect analysis confirmed the mediation effect of feedback-seeking behavior. By confirming the mediation effect of feedback-seeking behavior, this study draws attention to the importance of feedback-seeking behavior that has long been overlooked in research about information system use. This study also explores the factors that promote feedback-seeking behavior which in result could affect end user`s faithful appropriation of information systems. In addition, this study provides insight about which inducements or resources SMEs should offer to promote individual users' feedback-seeking behavior when formal and sufficient support from IT staff or an outside information system provider is hardly expected. As the study results show, under the business environment of SMEs, help from skilled colleagues and the management plays a critical role. Therefore, SMEs should seriously consider how to utilize skilled peer information system users, while the management should pay keen attention to end users and support them to make the most of information systems.

• Journal of Yeungnam Medical Science
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• 제9권1호
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• pp.29-43
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• 1992

1991년 5월 1일 부터 동년 8월 30일 사이에 영남대학교 의과대학 부속병원에서 위암 및 대장암으로 진단받은 환자 73명을 환자군으로, 건강진단을 받기 위해 동병원에 내원한 283명을 대조군으로 하여 셀레니움과 암과의 관련성을 보기 위한 환자-대조군 연구를 실시하였다. 환자군과 대조군의 성, 연령, BMI, 혈압, 혈청 총 콜레스테롤치, 음주, 흡연력을 조사하고 혈액과 손톱의 셀레니움 농도를 flameless furnace atomizer를 부착한 atomic absorption spectrophotometer를 이용하여 측정하였다. 환자군의 혈중 셀레니움 농도는 $143.6{\pm}10.8{\mu}g/l$로서 대조군의 $167.0{\pm}14.5{\mu}g/l$에 비해 유의하게 낮았으며(p<0.05), 발톱의 셀레니움 농도는 $1.04{\pm}0.62{\mu}g/g$로서 대조군의 $1.15{\pm}0.55{\mu}g/g$에 비해 낮게 나타났으나 통계적으로 유의하지는 않았다. 위암과 대장암사이의 혈중 및 발톱 셀레니움 농도의 차이는 유의하지 않았으며, 전이여부에 따른 셀레니움 농도의 차이도 유의하지 않았다. Multiple logistic regression analysis에 혈중 셀레니움 농도를 독립변수로 한 경우 혈중 셀레니움 농도($_aOR$: 0.888, 95% CI: 0.860-0.918)와 연령, BMI 및 혈청 총 콜레스테롤치가 유의한 변수로 나타났으며, 발톱 셀레니움 농도를 독립변수로 한 경우 연령($_aOR$ : 0.140, 95% CI: 1.085-1.199)만이 유의한 변수로 나타났으며 발톱 셀레니움 농도($_aOR$ : 0.870, 95% CI : 0.389-1.950)는 유의 하지 않았다. 이상의 성적은 셀레니움이 암의 발생을 억제한다는 가설과 일치하나 많은 예수, 다른 항산화작용 및 항암효과를 가지는 생화학물질들을 변수로 고려한 역학적 연구가 요망된다.

• 농약과학회지
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• 제13권3호
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• pp.190-196
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• 2009

소나무재선충 방제제로 등록되어 사용되고 있는 abamectin 1.8% 유제를 소나무와 잣나무에 나무주사 한 뒤 수체내에서 잔류량을 측정하였다. 소나무 수체 내에서 검출한계는 $0.05\;mg\;kg^{-1}$이었으며 회수율은 가지에서는 $0.5\;mg\;kg^{-1}$ 처리시 90.9%였으며 수간에서는 93.1%였다. 수고 15 m의 곰솔에서 나무주사 된 abamectin 1.8% 유제는 처리 150일 후 소나무재선충의 매개충인 솔수염하늘소의 섭식 부분인 모든 가지부분에서 0.29-$0.73\;mg\;kg^{-1}$이 검출되었다. 평균 흥고직경 12.6 cm의 곰솔 천연림에서 abamectin 1.8% 유제의 수체 내 잔류량을 조사 한 결과 개체목별로 차이가 많았다. 곰솔의 수간부분에서는 하부와 중부에서는 abamectin 수간주사 후 시간의 경과에 따라 잔류량이 감소하는 경향을 보였으며 상부에서는 주사 30일 후에 $1.84\;mg\;kg^{-1}$이 검출되어 처리 15일 후의 $0.65\;mg\;kg^{-1}$보다 많았으며 100일과 180일 이후에는 검출한계 이하로 검출되었다. 가지부분에서는 하부에서는 처리 180일 후에 $0.183\;mg\;kg^{-1}$이 검출되었으며 중부에서는 $0.173\;mg\;kg^{-1}$이 검출되었다. 흉고직경 20 cm, 수고 9 m의 잣나무에서 가지부분의 abamectin 평균 검출량은 $0.80\;mg\;kg^{-1}$이었으며 수간에서는 $0.30\;mg\;kg^{-1}$이었고, 흉고직경 15 cm, 수고 6 m의 잣나무에서는 가지부분 $0.67\;mg\;kg^{-1}$이 검출되었고, 수간에서는 $0.36\;mg\;kg^{-1}$이 검출되었다.

• 한국정보처리학회논문지
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• 제4권12호
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• pp.3159-3174
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• 1997

본 논문은 매우 방대하고 복잡한 실시간 소프트웨어를 이해하기 위한 하나의 방법론과 도구의 개발 연구에 대하여 보고한다. 대부분 본 논문의 저자에 의하여 개발된 이 방법론과 도구는 ARSU(Architecture-based Real-time Software Understanding)과 SRE(Software Re/reverse-engineering Environment)이다. 재공학과정중에 실시간 소프트웨어의 이해한다는 것은 방대한 규모와 복잡성 때문에 일반적으로 매우 어려운 일이다. 그러나 이러한 어려움을 극복하기 위하여 본 논문에서는 architecture에 근거하여 구조적 ${\cdot}$ 기능적 ${\cdot}$ 행위적 측면에서 3차원적인 이해를 가능하게 한다. 이 방법을 통하여 실시간 소프트웨어를 점진적이며 체계적으로 재${\cdot}$역공학할 수 있게 한다. 첫째, 구조적인 관점은 부모－자식간의 관계에 기초한 상하 층충적으로 이루어진 소프트웨어의 전체적 구조, 그리고 명세와 알고리즘 뷰들을 통하여 관측할 수 있다. 여기에서 구조를 구성하는 기본단위는 SWU(Software Unit)이며 이 SWU는 특정 기준에 준하여 추출된다. 이 구조는 상하 또는 그 역방향으로 소프트웨어를 항해(navigation) 할 수 있게 한다. 이는 소프트웨어에 대한 개요와 상세에 관한 정보를 분리하여 상호간에 연관성이 있게 보여준다. 구조의 어떤 단계, 즉 어떤 추상화 단계에서라도 소프트웨어에 대한 기능적 ${\cdot}$ 행위적 대한 정보를 얻을 수 있게 한다. 둘째, 기능적 뷰는 자료와 제어의 흐름, 입력과 출력, 정의와 사용, 변수와 참조 등을 보여준다. 이 뷰의 각 사항들은 소프트웨어에 대한 특정 기능 정보를 제공하여 준다. 셋째, 행위적 뷰는 상태도, IEL(interleaved event list) 등을 들 수 있다. 이 뷰는 소프트웨어에 대한 실행시 동적 성질을 보여준다. 이 뷰들 외에도 각 측면과 뷰들을 위한 기능, 접속, 주석, 코드 등의 다수의 서류들이 제공된다. 본 연구의 가장 큰 장점은 구조를 항해하면서 여러 차원의 정보를 추상화하거나 세부적으로 확장할 수 있는 기능이다. 이러한 기능들은 이러한 실시간 소프트웨어를 이해 할 수 있는 토대를 마련해 준다. 그리고 이러한 장점은 재사용 가능한 요소를 체계적으로 식별하거나 검증할 수 있게 한다.

• Korean Chemical Engineering Research
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• 제58권3호
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• pp.325-345
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• 2020

본 연구에서는 다매체 퓨가시티 모델을 기반으로 Volatile organic compounds (VOCs) 방지기술의 인체위해성·환경성·경제성 평가를 수행하여 석유화학 산업단지 내 VOCs 저감을 위한 최적가용기법(Best available technology, BAT)을 선정하였다. 다매체 퓨가시티 모델을 이용하여 U-city에 소재한 석유화학 산업단지에서 배출되는 VOCs 중 Benzene, Toluene, Ethylbenzene, Xylene (BTEX)의 다매체 거동 특성과 잔류농도 분포를 예측하였다. 매체 통합 인체위해성 평가 및 민감도 분석을 이용해 BTEX의 물질별 인체위해성을 예측하고 주요 영향 변수를 규명하였으며, 다매체 환경시스템 내 잔류농도 기준의 환경성 평가와 비용-편익 경제성 평가를 수행하여 우수환경관리기법군(BAT군)을 선정하였다. BTEX의 다매체 거동 분석 결과, 토양 매체에서 높은 잔류 분포 특성(60%, 61%, 64%, 63%)을 보였으며, Xylene은 모든 다매체 환경에서 가장 높은 잔류성을 보였다. BAT후보군 중에서 흡수법은 가장 높은 인체위해성을 보여 BAT 선정에서 제외하였으며, 민감도 분석 결과 대기 매체에서의 물질 반감기와 경로별 노출계수가 인체위해성과 높은 상관성이 있는 것으로 판단되었다. 환경성 평가와 비용-편익 경제성 평가를 고려하여, 재생 열산화법, 재생 촉매산화법, 바이오 필터법, UV 산화법, 활성탄 흡착법을 석유화학 산업단지 내 VOCs 저감을 위한 BAT군으로 선정하였으며, 본 연구에서 제시한 매체통합적 접근 방식의 BAT 선정 방법론은 사업장에서 오염물질 저감을 위한 최적의 배출시설 선정과 통합환경관리제도 운영에 기여할 수 있을 것으로 기대된다.

• 한국동물위생학회지
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• 제29권3호
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• pp.347-364
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• 2006

This study is concerned with assessment of diethylnitrosamine (DEN 0.01 %) induced liver cell carcinogenesis by measurement of changes preceding the development of neoplasms. Therefore, it was undertaken to investigate changes of liver-specific enzyme activities in Sprague-Dawley (SD) rats by ad libitum feeding of DEN. And also. the changes of hepatic morphology in SD rats were detected by haematoxylineosin stain and immunohistochemistry (PCNA). 5- Fluorouracil (5- FU) is one of the most widely used anticancer agents for digestive cancers including hepatocellular carcinoma, and is known to affect the cell cycle and induce apoptosis of cancer cells. In the present study, SD rats were given drinking water containing 0.01% diethylnitrosamine (DEN) for 8 weeks. Minor behavioral change, brittleness of hair and decreased amount of water and diet intake were observed in rats 4 weeks after DEN administration. The body and liver weights were significantly (p < 0.05) decreased in rats 11 weeks after DEN administration. The liver weight ratio to body weight was rather stable and not significantly decreased in the all treatment groups. The liver specific enzyme activities (AST, ALT, ${\gamma}$-GTP) were significantly increased in all treatment groups compared to control group (p < 0.05). Variable size of liver tumor and hepatomegaly were observed in rats treated with DEN after 10 weeks. Numerous vacuoles were seen on the midzonal and or peripheral areas of hepatic lobules. The large and polymorphological hepatocytes with eosinophilic cytoplasm or densely basophilic mitotic nucleoli were seen. Several proliferative small round cells were seen on vacuolated and necrotic areas in peripheral hepatic lobules or portal areas. PCNA-positive cells were seen on the vacuolated portal areas and peripheral areas of hepatic lobules in the areas of small round cells. We examined functional and morphological changes of livers by 5 - FU treatments on DEN -treated rat. The DEN -treated rats compared to 5 - FU -treated rats after DEN treatment for 8 weeks. The serum total protein and triglyceride were significantly (p < 0.05) decreased, and the liver enzyme activities of AST and ALT were significantly(p < 0.05) increased. After 8 weeks, in the non-5-FU -treated group, the size of liver tumor were varied and hepatomegaly were observed, hepatocellular vacuolization, necrosis and steatosis were observed on the midzonal and peripheral areas of hepatic lobules. The large and polymorphological hepatocytes were seen, the interlobular connective tissues were proliferated. PCNA positive cells were seen in the portal areas and peripheral areas of hepatic lobules in the non-5-FU-treated group. In hepatocytes, condensation of nuclear chromatin and vacuolization were observed, shape of the nuclei were irregular, the degraded nuclei and organelles were observed. The livers of rats in the 5 - FU treatment group were seen grossly brilliant, red-brown color, and the vacuolated and degenerated regions, hyperplastic nodules were not nearly observed. In the electron microscope, the cytoplasm of the hepatocytes contained a large number of mitochondria, rough endoplasmic reticulum, developed organelles surrounding nuclei. The above findings suggest that 5 - FU will be effective as anti -liver tumor drug.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제28권2호
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• pp.95-110
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• 2006

The treatment for oral and maxillofacial carcinoma with chemotherapeutic agents is evaluated by many effective methods to reduce the tumor mass and cancer cell proliferation. However these chemotherapy have many serious side effects, such as bone marrow suppression, renal toxicity, G-I troubles. Therefore a possible approach to develop a clinically applicable chemotherapeutic agent is to screen anticancer activity of Taxol which is known to have very little side effect and have been used to breast cancer and ovarian carcinoma. Taxol is a new anti-microtubular anti-cancer agent extracted from the bark of the Pacific yew, Taxus brevifolia. Paclitaxel(Taxol) acts by promoting tubulin polymerization and over stabilizing microtubules agianst depolymerization. Despite the constant improvements of methods of the cancer treatment especially chemotherapy, the rate of cancer metastasis and recurrent are not decreased. Thus the investigation of new drug which have very little side effect and a possible clinically application continues to be a high priority. Considering that the Taxol have shown very effective chemotherapeutic agent with relatively low toxicity in many solid tumors, it deserves to evaluate its efficacy in oral squamous cell carcinoma. In this study, to investigate the in-vivo and in-vitro anti-cancer efficacy of Taxol in oral squamous cell carcinoma and lastly, the potency of Paclitaxel in the clinical application for oral cancer was evaluated. In vivo study, after HN22 cell line were xenografted in nude mice, the growth of tumor mass was observed, 3 mg/Kg taxol was injected intraperitoneally into nude mice containing tumor mass. The methods of these study were measurement of total volume of tumor mass, histopathologic study, immunohistochemical study, drug resistance assay, growth curve, MTT assay, flow cytometry, cDNA microarray in vivo and in vitro. The results were obtained as following. 1. The visual inspection of the experimental group showed that the volume of the tumor mass was slightly decreased but no significant difference with control group. 2. Ki-67 index was decreased at weeks 4 in experimental group. 3. Microscopic view of the xenografted tumor mass showed well differentiated squamous cell carcinoma and after Taxol injection, some necrotic tissue was seen weeks 4. 4. The growth curve of the tumor cells were decreased after 1day Taxol treatment. 5. According to the MTT assay, HN22 cell line showed relative drug resistancy above $5\;{\mu}g/ml$ concentrations of Taxol. 6. In drug resistance assay, the decrease of cell counts was seen relatively according to concentration. 7. In Flow cytometry, G2M phase cell arrests were seen in low concentration of the Taxol, while S phase cell arrests were seen in high concentration of the Taxol. 8. Using cDNA microarray technique, variable gene expression of ANGPTL4, TXNRD1, FAS, RRAGA, CTGF, CYCLINEA, P19, DUSP5, CEBPG, BTG1 were detacted in the oral squamous cell carcinoma cell after taxol treatment. In this study paclitaxel is effective against oral squamous cell carcinoma cell lines in vitro, but week effect was observed in vivo. So we need continuous study about anticancer effect of taxol in vivo in oral squamous cell carcinoma.

• 한국응용곤충학회지
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• 제18권1호
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• pp.1-10
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• 1979

1975년 수원 잠업시험장에서 분리한 흰불나방 핵다각체 바이러스 성상과 령기, 화기별 및 병원체 보존조건에 따른 병원성을 검정하기 위하여 핵다각체 바이러스를 현탁액 및 건조시켜 실온$(18.5^{\circ}C)$, 냉장$(5^{\circ}C)$, 냉동$(-80^{\circ}C)$에 각각 보존, 이병사체는 그대로 양지 음와 지에 보존하였고 야외에서의 병원성, 가잠에 대한 교우감염을 검정한 결과 다음과 같다. 1. 흰불나방 핵다각체는 4면체와 6면체로 크기는 약 $2.0{\mu}$이고 바이러스 입자는 간상형의 $2\~12$본으로 $33m\mu\times35m\mu$이었다. 2. 6각형의 흰불나방 중장핵다각체 바이러스는 중장의 핵에서만 발견되었다. 3. 령기별 $LD_{50.}$ 2,3,4 및 5령에 대해 $8.377\times10^4,\;4.974\times10^5,\;2.621\times10^6$ 및 $9.471\times10^6PIBs/ml$ 였으며 $1.45\times10^6\;PIBs/ml$에 대한 $LT_{50}$은 각각 9.6, 11.5, 12.0 및 17.3일 이었다. 4. 핵다각체 바이러스는 1화기 유충보다 2화기 유충에서 감수성이 높았다. 5. 핵다각체 보존은 둔화건조하여 냉동 및 냉장보존하거나 이병사체를 음지에 보존하는 것이 바이러스 활성도의 감소가 적었다. 6. 야외에서의 효과적인 살포농도는 $6.4\times10^7\;PIBs/ml$이며 이의 $LT_{50}$은 3령은 4.8일, 5령은 14.2일이었다. 7. 흰불나방 핵다각체 바이러스와 가잠의 핵다각체 바이러스는 상호 교우감염을 일으키지 않았다.

• Clinical and Experimental Pediatrics
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• 제46권11호
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• pp.1061-1066
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• 2003

목 적: 소아비만은 단기간에 전세계적으로 증가하였다. 이는 에너지 섭취 과다와 소모 부족으로 인한 에너지 불균형으로 여겨진다. 최근 다양한 종류의 음료 상품이 개발되면서 소아의 음료 섭취량이 늘고 있어 저자들은 소아비만에서 음료 섭취량을 파악하여 소아비만의 예방과 관리에 도움을 얻고자 본 조사를 실시하였다. 방 법: 2003년 5월에 서울시 송파구 내 초등학생 총 877명 (남녀비 1 : 1.02, 평균 나이 9.7세)을 대상으로 하였다. 신장과 체중을 측정하여 체질량지수를 산출하여 비만군, 과체중군, 정상군으로 나누었으며 설문지로 부모의 체질량지수, 사회경제적 요인, 3일간 섭취한 음식과 칼로리 및 음료 섭취량을 조사하였다. 음료는 우유, 요구르트 같은 기타 유제품, 탄산음료, 스포츠음료, 쥬스, 인공 착색 음료를 비롯한 기타 음료로 세분화하여 조사하였다. 음료는 우유, 요구르트 같은 기타 유제품, 탄산음료, 스포츠음료, 쥬스, 인공착색 음료를 비롯한 기타 음료로 세분화하여 조사하였다. 결 과 : 1) 대상아의 비만 유병률은 7.2%이었다. 2) 비만군의 어머니와 아버지의 체질량지수가 과체중군, 정상군에 비해서 유의하게 높았다(P<0.001). 3) 출생시 체중은 비만과 유의한 관련이 없었다(P=0.183). 가정의 월수입(P=0.266), 아버지의 학력(P=0.489), 어머니의 학력 (P=0.285)과 상관관계가 없었다. 4) 하루 총 칼로리 섭취량과 음식의 종류는 비만군, 과체중군, 정상군에서 유의한 차이가 없었다. 5) 7-9세 남아 비만군은 탄산음료, 스포츠 음료 섭취량이 다른 군에 비해 유의하게 많았다(P<0.001). 10-12세 남아 비만군은 총 음료 섭취량이 다른 군에 비해 유의하게 많았고(P=0.002), 인공 착색 음료를 비롯한 기타 음료 섭취에서 비만군이 다른 군에 비해 유의하게 많았다(P=0.012). 10-12세 여아 비만군은 기타 유제품 섭취에 있어 다른 군에 비해 유의하게 많았다 (P=0.002). 결 론 : 소아에서 음료의 과다 섭취는 비만으로 이어질 수 있다. 소아에서 음료 섭취를 조절하는 것이 최근 증가되는 비만의 유병률을 감소시킬 수 있는 한 가지 방법이 될 것으로 사료된다.