• 동의신경정신과학회지
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• 제15권1호
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• pp.27-41
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• 2004

This study was performed to evaluate the effects of Jowiseungchungtang and fluoxetine in the chronic mild stress(CMS) model of depression in rats. Chronic exposure to mild unpredictable stress was found to depress the consumption of sucrose solution in rats for 5 weeks. These CMS-treated rats were stratified into Jowiseungchungtang group, fluoxetine group and vehicle group. And control rats were also stratified into other CMS-treated group. The change of the consumption of sucrose solution was measured, and open field test were performed to investigate the anti-depression effect of Jowiseungchungtang and fluoxetine. The results were as follows : 1. The consumption of sucrose solution was significantly reversed in Jowiseungchungtang-treated group at 7 week, but there was no significant change in other groups. 2. CMS schedule decreased body weight. Jowiseungchungtang group and fluoxetine group showed significant decrease of body weight after 6 weeks. 3. In open field test, Jowiseungchungtang group and fluoxetine group showed no significant change of exploratory activity.

• 사상체질의학회지
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• 제15권1호
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• pp.109-117
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• 2003

There have been several the reports that the mechanism of Sasang consititution might be understood in the level of genes. Previous study of the authors showed that HLA types and constitutional information had significant relationships. One hundred subjects who showed Taeum characteristics were selected in the present study. HLA-A, HLA-B, HLA-DRB1, ACE, ${\beta}-IIAR$, ${\beta}-IIIAR$, UCP-1, and ALDH2 polymorphisms were analyzed. Also, ACE, ${\beta}-IIAR$, ${\beta}-IIIAR$, UCP-1, and ALDH2 analyses were performed on the 100 samples of previous study who showed Taeyang characteristics. Despite of several significant differences of HLA allele frequencies between Taeum-inclined group and normal control group, this significance level was not sufficient ro support the association between constitution and HLA genes, because of the raised alpha error rate. The polymorphisrns of ACE, ${\beta}-IIAR$, ${\beta}-IIIAR$, UCP-1, and ALDH2 genes did not show relationship between Taeyang-inclined and Taeum-inclined groups, whereas BMI showed difference between Taeyang-inclined and Taeum-inclined groups. ALDH2 in Taeyang-inclined group confirmed the protective role of ALDH2*2 allele against alcoholism.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2005년도 춘계학술발표대회 개요집
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• pp.276-278
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• 2005

Bridge constructed recently is preferred to have a long span and a simple structure detail considering not only functions as bridge but scenic beauty, maintenance, construction term and life cycle cost, etc. Therefore, it demands a high quality steel like a thick plate steel and a high performance steel. A TMCP steel produced by theme-mechanical control process is now spotlighted due to the weldability for less carbon equivalent. It improved at strength and toughness in microstructure. Resently the SM570-TMC steel, a high strength TMCP steel whose tensile strength is 600MPa, is developed and applied to steel structures. But, for the application of this steel to steel structures, it is necessary to elucidate not only the material characteristics but also the mechanical characteristic of welded joint. In this paper, we investigated the characteristics of residual stresses generated by welding of SM570-TMC steels through an experimental study

• 한국재료학회지
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• 제12권5호
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• pp.363-368
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• 2002

we proposed the use of $Si_2H_ 6/H_2$ chemistry for selective silicon epitaxy growth by low-pressure chemical vapor deposition(LPCVD) in the temperature range $600~710^{\circ}C$ under an ultraclean environment. As a result of ultraclean processing, an incubation period of Si deposition only on $SiO_2$ was found, and low temperature epitaxy selective deposition on Si was achieved without addition of HCI. Total gas flow rate and deposition pressure were 16.6sccm and 3.5mtorr, respectively. In this condition, we selectively obtained high-quality epitaxial Si layers of the 350~1050$\AA$ thickness. In older to extend the selectivity, we kept high pressure $H_2$ environment without $Si_2H_6$ gas for few minutes after first incubation period and then we conformed the existence of second incubation period.

• 융합신호처리학회논문지
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• 제10권2호
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• pp.127-131
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• 2009

디지털 도파관 모델은 파동 방정식의 일반해를 이용하여 진행파를 표현하고 이 진행파의 파동이동을 지연 라인으로 나타낸다. 일반적인 도파관 모델에서의 단일 지연은 샘플링 시간 간격을 의미하지만, 공간 기준 도파관 모델의 단일 지연은 샘플링된 공간의 거리를 의미한다. 이러한 차이점으로 인해 파동의 이동 거리를 직접적으로 조절할 수 있는 공간기준 도파관 모델이 비브라토 음과 같이 피치가 변하는 음을 합성할 수 있다고 알려져 있다. 본 논문에서는 지연라인의 길이의 비로서 피치가 변하는 음을 합성할 수 있는 시간 기준 디지털 도파관 모델을 제안하고 기존의 공간 기준 도파관 모델과의 성능을 비교하였다.

• 한국학교ㆍ지역보건교육학회지
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• 제2권1호
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• pp.19-30
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• 2001

Korea has experiencing outbreaks of food borne illnesses since school feeding programs had been introduced to students. In order to prevent food borne diseases, preventive measures applicable to Korean school system were reviewed. The conclusions are summarized as follows; 1. Raw materials should be purchased through reliable sources in order to ensure the quality of food stuffs in the aspect of food safety and hygiene. 2. The potential causes of food borne illnesses should be carefully identified and control system should be established in order to monitor critical points. 3. Temperature of refrigeration should be monitored and controled continuously in order to safeguard the quality of foods. 4. National and local governments have to provide adequate equipment and utensils to the food establishments of school systems, and public health authorities have to make evaluation of the facilities periodically. The food handlers should be trained in safe food handling and the ways how to prevent food borne illnesses.

• Macromolecular Research
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• 제17권3호
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• pp.192-196
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• 2009

Recently, the multi-screening of target materials has been made possible by the development of the surface plasmon resonance (SPR) imaging method. To adapt this method to biochemical analysis, the multi-patterning technology of protein microarrays is required. Among the different methods of fabricating protein microarrays, the microfluidic platform was selected due to its various advantages over other techniques. Microfluidic devices were designed and fabricated with polydimethylsiloxane (PDMS) by the replica molding method. These devices were designed to operate using only capillary force, without the need for additional flow control equipment. With these devices, multiple protein-patterned sensor surfaces were made, to support the two-dimensional detection of various protein-protein interactions with SPR. The fabrication technique of protein microarrays can be applied not only to SPR imaging, but also to other biochemical analyses.

• 지구물리
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• 제9권2호
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• pp.129-134
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• 2006

Recently, spillways are need to control stable water level for supporting main dams because of floods by unusual change of weather such as Typhoon Rusa. This study has been focused on the amount of leakage through the rock mass distributed fractures and joints under the opened emergency spillway. It is very important to evaluate the amount of leakage as these affect stability of spillway by interaction between effective stress and pore pressure. The commercial program MAFIC has been used for analyzing groundwater flow in fractured rock mass. The results showed that the values of range, average and deviation of leakage were 2.85∼3.79×10-1, 3.32×10-1 and 1.70×10-2 m3/day/m2 respectively. Secondary, we have estimated the effect of grouting after the transmissivity(Tf) of joint 1 as main pathway of leakage known from above results was changed from 1.78×10-7 to 1.59×10-9 m2/s. The results showed that the values of range, average and deviation of leakage were 7.80×10-4∼1.53×10-3, 1.18×10-3 and 1.32×10-4 m3/day/m2 respectively. As the result, the amount of leakage after grouting has been decreased by a ratio of 1 to 277.

• Integrative Medicine Research
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• 제6권1호
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• pp.12-18
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• 2017

Cryopreservation is a process that preserves organelles, cells, tissues, or any other biological constructs by cooling the samples to very low temperatures. The responses of living cells to ice formation are of theoretical interest and practical relevance. Stem cells and other viable tissues, which have great potential for use in basic research as well as for many medical applications, cannot be stored with simple cooling or freezing for a long time because ice crystal formation, osmotic shock, and membrane damage during freezing and thawing will cause cell death. The successful cryopreservation of cells and tissues has been gradually increasing in recent years, with the use of cryoprotective agents and temperature control equipment. Continuous understanding of the physical and chemical properties that occur in the freezing and thawing cycle will be necessary for the successful cryopreservation of cells or tissues and their clinical applications. In this review, we briefly address representative cryopreservation processes, such as slow freezing and vitrification, and the available cryoprotective agents. In addition, some adverse effects of cryopreservation are mentioned.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2019년도 춘계학술대회
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• pp.193-196
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• 2019

Digital Game design with educational purposes and User Experience measurement via game analytics has been extensively covered in literature, however non-digital games such as tabletops in education and its corresponding educational impact have limited research. In this paper, we propose a guideline to create non-digital educational games from scratch and evaluate them based on the know-how of developers and the investigation of scholars who have studied the engagement factors related to the digital games and applied their findings to non-digital games. Along with the guideline we provide an actual implementation, a game called HXGN_766, meant to serve as scaffolding of computational thinking and rudimentary Python programing concepts. We believe both, guideline and game, can be a useful reference for those interested on game design, educational content design, game quality control check, and unplugged computer science activities. This is the first in a series of papers where the game design concept, the evaluation methodology and the game itself will be presented with more detail.