• Journal of Periodontal and Implant Science
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• v.32 no.4
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• pp.753-767
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• 2002

The purpose of this study was to evaluate histologically the effect of LiF-maleic acid added calcium aluminate(LM-CA) bone cement & CA-PMMA composite bone cement on the healing of calvarial defect in Sprague-Dawley rats. The critical size defects were surgically produced in the calvarial bone using the 8mm trephine bur. The rats were divided in three groups : In the control group, nothing was applied into the defect of each rat. LM-CA bone cement was implanted in the experimental group 1 and CA-PMMA composite bone cement was implanted in the experimental group 2. Rats were sacrificed at 2, 8 weeks after surgical procedure. The specimens were examined by histologic analysis, especially about the bone-cement interface and the response of surrounding tissue. The results are as follows; 1. In the control group, inflammatory infiltration was observed at 2 weeks. At 8 weeks, periosteum and duramater were continuously joined together in the defect area. But the center of defect area was filled up with the loose connective tissue. 2. In the experimental group 1, the bonding between implanted bone cement and the existing bone was seen, which more increased in 8 weeks than 2 weeks. Inflammatory infiltration and the dispersion of implanted bone cement particles were seen in both 2 weeks and 8 weeks. 3. In the experimental group 2, implanted bone itself had a dimensional stability and no bonding between implanted bone cement and the existing bone was seen in both 2 weeks and 8 weeks. Implanted bone cement was encapsulated by fibrous connective tissue. In addition, inflammatory infiltration was seen around implanted bone cement. On the basis of these results, when LM-CA bone cement or CA-PMMA composite bone cement was implanted in rat calvarial defect, LM-CA bone cement can be used as a bioactive bone graft material due to ability of bonding to the existing bone and CA-PMMA can be used as a graft material for augmentation of bone-volume due to dimensional stability.

• Journal of Periodontal and Implant Science
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• v.44 no.5
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• pp.242-250
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• 2014

Purpose: This study aimed to evaluate the effects of fibronectin and oxysterol immobilized on machined-surface dental implants for the enhancement of cell attachment and osteogenic differentiation, on peri-implant bone healing in the early healing phase using an experimental model in dogs. Methods: Five types of dental implants were installed at a healed alveolar ridge in five dogs: a machined-surface implant (MI), apatite-coated MI (AMI), fibronectin-loaded AMI (FAMI), oxysterol-loaded AMI (OAMI), and sand-blasted, large-grit, acid-etched surface implant (SLAI). A randomly selected unilateral ridge was observed for 2 weeks, and the contralateral ridge for a 4-week period. Histologic and histometric analyses were performed for the bone-to-implant contact proportion (BIC) and bone density around the dental implant surface. Results: Different bone healing patterns were observed according to the type of implant surface 2 weeks after installation; newly formed bone continuously lined the entire surfaces in specimens of the FAMI and SLAI groups, whereas bony trabecula from adjacent bone tissue appeared with minimal new bone lining onto the surface in the MI, AMI, and OAMI groups. Histometric results revealed a significant reduction in the BIC in MI, AMI, and OAMI compared to SLAI, but FAMI demonstrated a comparable BIC with SLAI. Although both the BIC and bone density increased from a 2- to 4-week healing period, bone density showed no significant difference among any of the experimental and control groups. Conclusions: A fibronectin-coated implant surface designed for cell adhesion could increase contact osteogenesis in the early bone healing phase, but an oxysterol-coated implant surface designed for osteoinductivity could not modify early bone healing around implants in normal bone physiology.

• Journal of Korean Society of Forest Science
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• v.99 no.1
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• pp.153-162
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• 2010

Abies holophylla Maxim. is a shade tolerant species that has potential to be used for continuous cover forestry system. Stand structure and natural regeneration of A. holophylla stands in Yong-In area located in the central part of Korea was investigated to estimate the self sustainability of A. holophylla plantation. Species composition, diameter at breast height (DBH) and height distribution of trees larger than 2 cm DBH were measured in ten stands in three study sites of Jeongsu-ri, Daedae-ri, and Hodong. Species and coverage of shrub layer, and A. holophylla seedlings were also investigated. While A. holophylla in non-managed stands (Jengsuri and Daedae-ri study sites) had the importance value of 40% and showed continuous diameter and age distribution, A. holophylla in Hodong site had narrow bell-shaped DBH distribution mostly concentrating between 25-35 cm DBH classes, and single canopy structure. Abies holophylla stands in Hodong have experienced occasional thinning and selective cutting. The correlation coefficient between age-DBH was significant but low ($R^2$=0.2, P=0.03), and similar aged A. holophylla had diverse DBH values. Continuos DBH distribution and multi-canopy structure of A. holophylla stands in Jeongsu-ri site show that natural regeneration of A. holophylla has been continuously occurred in this area. Seedling density of A. holophylla was between 2000 and 33000/ha, however, the number of trees in 2-5 cm DBH class was only 40-150 trees/ha, implying that the survival rate of seedlings is not high. Continuous natural regeneration and 0.6 cm/year of diameter growth rate of A. holophylla indicate that this area could be an appropriate habitat for this species, and A. holophylla plantation in this region seem to persist suggesting the possibility of managing the stands for continuous cover forestry system as well as selective harvesting practices.

• Journal of Periodontal and Implant Science
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• v.32 no.1
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• pp.89-112
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• 2002

The earliest reports of the use of electrical energy to directly stimulate bone healing seem to be in 1853 from England, the techniques involved the introduction of direct current into the non-united fracture site percutaneously via metallic needles, with subsequent healing of the defect. One endpoint of the periodontal therapy is to generate structure lost by periodontal diseases. Several procedural advances may support regeneration of attachment, however, regeneration of alveolar bone does not occur consistently. Therefore, factors which stimulate bone repair are areas for research in periodontal reconstructive therapy. Effects of cytokines or growth factors on bone repair are examples of such areas. Another one is electrical current which occurs in bone naturally, so that such bone may be particularly susceptible to electrical therapy. The purposes of this study were to observe the effects of electrical stimulation on the normal periodontium, to determine whether the electricity is the useful means for periodontal regeneration or not. Forty rats weighted about 100 gram were used and divided into 4 groups, the first group, there was no electrical stimulation with the connection of electrodes only. In the second group, there was stimulated by the 10 mA during 10 minutes per a day, in the third group was stimulated by the 25 mA , and the fourth by the 50 mA. At 3, 5, 10 and 15 days post-appliance , two rats in each group were serially sacrificed. and the maxillae and the mandible processed to paraffin, and the specimens were prepared with Hematoxylin-Eosin stain for the light microscopic evaluation. The results of this study were as follows : 1. There was the distinct reversal line on the lingual alveolar crest, whereas a little changes in the labial alveolarcrest to the duration and amount of currents. 2. In 50 mA group, the cells were highly concentrated at the apex of anterior teeth, and was observed the necrotic tissue. In posterior root apex, the hypercementosis was appeared, and newly formed cementum layer has been increased continuously with the time. 3. The periodontal ligament fiber and Sharpey's fiber were arranged in order, and the bone trabeculae were increased as the experiment proceeded by, relatively the bone marrows were decreased. 4. In the pulp tissue, the blood vessels were increased with blood congestion in the experimetal specimens remarkably, and the dentinal tubules were obstructed . 5. The osteoblasts in alveolar bone proper had been showed highly activity, and also observed the formation of bone trabeculea. In the conclusion, it was suggested that the electrical stimulation has influence on the periodontium and the pulp tissue. However, there might be the injurious effects.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.39 no.6
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• pp.571-585
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• 2021

Various studies have analyzed urban decline at a universal level using the general characteristics of declining cities. However, urban decline at the city level should be considered because this decay occurs based on the unique attributes of a particular city. In addition, since this phenomenon occurs and spreads in microspaces, studies should consider smaller spatial units continuously. This study aims to develop an urban decline measurement model that considers regional characteristics to analyze the urban decline of Ulsan Metropolitan City over time and space. The index value of Ulsan, compared to the national average, is calculated and reflected in the weight to reflect regional characteristics in the model. In addition, after analyzing urban decline by administrative dong units, we also performed analysis by counting district units using spatial hierarchical structure to demonstrate evaluation on smaller unit spaces. As a result of analyzing urban decline patterns by associating the index calculated using the model with the social phenomenon of Ulsan Metropolitan City, urban decline formed clusters and spread to adjacent regions over time. In addition, results confirmed that external factors such as new towns and urban regeneration projects affect urban decline. By illustrating the degree of urban decline proposed measurement model used in this study, it is possible to present the priority of areas required for urban regeneration projects. Results are also helpful to test the effectiveness of completed or presently-implemented urban regeneration projects.

• Journal of Environmental Science International
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• v.15 no.12
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• pp.1119-1124
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• 2006

Height-growth analysis was used to examine forest structure and compare Pterocarya rhoifolia and Fraxinus spaethiana growth characteristics within and between each species in two P. rhoifolia-dominant and two F. spaethiana established contemporaneously in the sere, species vertical stratification 25 years after stand initiation was such that P. rhoifolia dominated the overstory but F. spaethiana the understory, including that P. rhoifolia grew about 4 times more rapidly Similarly, F. spaethiana dominated the overstory but not the understory, in a stand where it established mainly by itself, 25 years after Initiation. However, comparing the two different stands, P. rhoifolia overstory heights were about two times greater than F. spaethiana. This suggests that in a disturbance regime, forest regeneration is affected by height-growth patterns such that P. rhoifolia's ability to achieverapid height growth allows it to dominate where lights growth allows it to dominate where light resources are continuously abundant.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.8 no.2
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• pp.119-128
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• 2022

2-Dimensional inorganic nanoparticles with high surface area and ion-exchangeable properties have been continuously growing based on nanotechnology in the field of nanomedicine. Among one of the 2-D nanoparticles, layered double hydroxide (LDH) has been intensively explored as drug delivery due to its low toxicity, enhanced cellular permeability, and high drug loading capacity. Moreover, controllable chemical composition makes possible varying isomorphic layered materials for therapy and imaging of diseases. In this review, specific structural characteristics of LDH were introduced, and its potential for application as a biocompatible therapeutic agent and diagnostic one was addressed in nuclear medicine, one of promising fields in nanomedicine.

• Journal of Environmental Science International
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• v.17 no.11
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• pp.1255-1263
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• 2008

The efficiency of PP-g-AA and PP-g-St nonwoven fabric synthesized by photoinduced polymerization as an adsorbent for removal $NH_3-N$ from waste water was evaluated. The results evidently indicate that the adsorption capacities of $NH_3-N$ onto PP-g-AA nonwoven fabric were extremely superior to those onto sulfonated PP-g-St nonwoven fabric, PK and zeolite. PP-g-AA nonwoven fabric showed the maximum adsorption capacity of $NH_3-N$ at the degree of grafting of 80 wt.%. The adsorption behaviour of $NH_3-N$ onto PP-g-AA and sulfonated PP-g-St nonwoven fabric was controlled by an ion exchange reaction, and tended to be similar to both trends of Langmiur and Freundlish isotherm. Futhermore, PP-g-AA non-woven fabric could be regenerated more than 5 times by a simple washing with 0.1N HCl with no decrease of adsorption capacity and no degradation of physical properties. Also sulfonated PP-g-St nonwoven fabric could be regenerated by washing with 0.1N ${H_2}{O_4}$. However, their regeneration efficiency was significantly low because grafting layer acted as functional radical for adsorption was continuously desquamated in the adsorption or regeneration processes, which resulted in decrease of adsorption capacity and weight of adsorbent. All results obtained from this study indicate that the $NH_3-N$ removal capacity of PP-g-AA non-woven fabric was extremely superior to those of PP-g-St non-woven fabric, PK and zeolite.

• Transactions of the Korean Society of Automotive Engineers
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• v.13 no.2
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• pp.52-57
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• 2005

The increasing automobiles continue to cause air-pollution problem s worse than ever. In fact, many automobile research are involved in how to reduce exhaust emissions effectively specially in $NO_X$ and PM to comply with stringent emission standards, Euro V. This research emphasized on the development of continuous regeneration DPF technology which was one of promising removing technology of particulate matters because of its comparability and high applicability. In addition, this research discussed on some design points of view through correlation study by com paring the experimental data with computational results by the introduction of commercial codes such as CFD-ACE+ and KIVA-3V. The numerical simulation on the performance of continuous regeneration DPF apparatus and corresponding emission characteristics has been predicted well enough and verified with experimental results. The pressure and average temperatures are decreased to about 2.6% and 1.4% respectively under a full engine load condition mainly due to back pressures raised by diesel particulate filter. Pressure, temperature and heat releasing rates tend to decrease specially at higher engine load, but they are not affected at lower engine load regions.

• Journal of the Korean Society of Industry Convergence
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• v.23 no.4_2
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• pp.701-708
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• 2020

In this paper, we analyzed the optical properties of the LED module for dental care, which has the effect of promoting cell regeneration and scar treatment. The LED module is a U-shaped module suitable for the shape of teeth. It is manufactured with an LED module (632 nm) and an LED module (632 nm + 870 nm), analyzes the results of optical properties, sets the irradiation distance, irradiation time, and is effective in healing skin wounds. Evaluation was conducted. It was tested in 6 test groups according to the light irradiation conditions, and light was irradiated to the scar site every other day for 7 days, 1 day and 3 days. As a result, it was confirmed that the effect of scar treatment was the highest when the combined wavelength of 632 nm + 870 nm was irradiated in pulse mode than when the single wavelength was irradiated and the composite wavelength was continuously irradiated. In group C group irradiated with PW Mode: pulse mode (period 36 ms, pulse width 35 ms) using a composite wavelength with LED module (632 nm + 870 nm) than group A without light irradiation, the length of scar reduction was 19 %, the area of the scar was further reduced by 10%, and it was confirmed that it is effective in treating scars in the wound area.