• Title/Summary/Keyword: Continuous flow system

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Immobilization of Photobacterium Phosphoreum for Monitoring of Toxic Substances

  • Uck-Han Chun;Jun
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.2 no.2
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    • pp.141-146
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    • 1997
  • A new sensing system based on the immobilization of luminescent batcteria, Photobacterium phosphoreum, was proposed for continuous real-time monitoring of polluants. The response curves demonstrate that Photobacterium phosphoreum immobilized on the strontium alginate was very sensitive to seven reference chemicals used. The significant inhibitory concentrations for bioluminescence emission were 5 ppm for Pb(NO3)2, NiCl2, CdCl2, 50 ppm for NaAsO2, 0.1ppm for HgCl2, 0.5ppm for pentachlorophenol and less than 5ppm for SDS, respectively. The alginate mixed-cells (AMC) retained their luminescence during experimental period (29 days) under storage condition of -8$0^{\circ}C$. The variables affecting performance of continuous flow through monitoring (CFTM) were optimized in order to ensure stability and efficiency. The flow through cell with strontium-alginate immobilized luminescent bacteria was tested with salicylate and 4-nitrophenol and a rapid response of luminescence was recorded by time drive mode in bioluminescence spectrometer after exposure to both toxicants.

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Statistical Process Control System for Continuous Flow Processes Using the Kalman Filter and Neural Network′s Modeling (칼만 필터와 뉴럴 네트워크 모델링을 이용한 연속생산공정의 통계적 공정관리 시스템)

  • 권상혁;김광섭;왕지남
    • Journal of the Korean Society for Precision Engineering
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    • v.15 no.3
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    • pp.50-60
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    • 1998
  • This paper is concerned with the design of two residual control charts for real-time monitoring of the continuous flow processes. Two different control charts are designed under the situation that observations are correlated each other. Kalman-Filter based model estimation is employed when the process model is known. A black-box approach, based on Back-Propagation Neural Network, is also applied for the design of control chart when there is no prior information of process model. Performance of the designed control charts and traditional control charts is evaluated. Average run length(ARL) is adopted as a criterion for comparison. Experimental results show that the designed control chart using the Neural Network's modeling has shorter ARL than that of the other control charts when process mean is shifted. This means that the designed control chart detects the out-of-control state of the process faster than the others. The designed control chart using the Kalman-Filter based model estimation also has better performance than traditional control chart when process is out-of-control state.

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Two-Phase Jet Flow Characteristics in the Pure Oxygen Aeration System Using Two-phase Jet Nozzle (이상 제트 노즐을 사용한 순산소 폭기시스템의 이상유동 특성)

  • Jung, Chan-Hee;Lee, Kye-Bock
    • Journal of Energy Engineering
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    • v.18 no.4
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    • pp.258-263
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    • 2009
  • Jet Loop Reactor(JLR), in which a two-phase nozzle is installed, is the new design technique for the treatment of high concentration wastewater by accelerating of oxygen contacting between substrate and surrounding bacteria. This numerical study of the two phase jet flow was conducted to find the optimum design of JLR. It was shown that there was a minimum velocity in the nozzle for continuous circulation of wastewater. The optimum location and the size of the draft tube for continuous circulation were examined. It was certain that the smaller the air size is, the more the effect of the mixing increases. The relation between the mixing effect and the turbulence was confirmed.

Electrooxidation of tannery wastewater with continuous flow system: Role of electrode materials

  • Tien, Tran Tan;Luu, Tran Le
    • Environmental Engineering Research
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    • v.25 no.3
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    • pp.324-334
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    • 2020
  • Tannery wastewater is known to contain high concentrations of organic compounds, pathogens, and other toxic inorganic elements such as heavy metals, nitrogen, sulfur, etc. Biological methods such as aerobic and anaerobic processes are unsuitable for tannery wastewater treatment due to its high salinity, and electrochemical oxidation offers a promising method to solve this problem. In this study, raw tannery wastewater treatment using DSA® Ti/RuO2, Ti/IrO2 and Ti/BDD electrodes with continuous flow systems was examined. Effects of current densities and electrolysis times were investigated, to evaluate the process performance and energy consumption. The results showed that a Ti/BDD electrode is able to reach higher treatment efficiency than Ti/IrO2, and Ti/RuO2 electrodes across all parameters, excluding Total Nitrogen. The main mechanism of tannery wastewater oxidation at a Ti/BDD electrode is based on direct oxidation on the electrode surface combined with the generation of oxidants such as °OH and Cl2, while at DSA® Ti/RuO2 and Ti/IrO2 electrodes, the oxidation mechanisms are based on the generation of chlorine. After treatment, the effluents can be discharged to the environment after 6-12 h of electrolysis. Electrooxidation thus offers a promising method for removing the nutrients and non-biodegradable organic compounds in tannery wastewater.

Application Consideration of Machine Learning Techniques in Satellite Systems

  • Jin-keun Hong
    • International journal of advanced smart convergence
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    • v.13 no.2
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    • pp.48-60
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    • 2024
  • With the exponential growth of satellite data utilization, machine learning has become pivotal in enhancing innovation and cybersecurity in satellite systems. This paper investigates the role of machine learning techniques in identifying and mitigating vulnerabilities and code smells within satellite software. We explore satellite system architecture and survey applications like vulnerability analysis, source code refactoring, and security flaw detection, emphasizing feature extraction methodologies such as Abstract Syntax Trees (AST) and Control Flow Graphs (CFG). We present practical examples of feature extraction and training models using machine learning techniques like Random Forests, Support Vector Machines, and Gradient Boosting. Additionally, we review open-access satellite datasets and address prevalent code smells through systematic refactoring solutions. By integrating continuous code review and refactoring into satellite software development, this research aims to improve maintainability, scalability, and cybersecurity, providing novel insights for the advancement of satellite software development and security. The value of this paper lies in its focus on addressing the identification of vulnerabilities and resolution of code smells in satellite software. In terms of the authors' contributions, we detail methods for applying machine learning to identify potential vulnerabilities and code smells in satellite software. Furthermore, the study presents techniques for feature extraction and model training, utilizing Abstract Syntax Trees (AST) and Control Flow Graphs (CFG) to extract relevant features for machine learning training. Regarding the results, we discuss the analysis of vulnerabilities, the identification of code smells, maintenance, and security enhancement through practical examples. This underscores the significant improvement in the maintainability and scalability of satellite software through continuous code review and refactoring.

Computational Fluid Dynamic Analysis for Improving the Efficiency of Desulfurization System for the Wet Flue Gas (습식 배연탈황 시스템의 효율 향상을 위한 전산해석)

  • Hwang, Woo-Hyeon;Lee, Kyung-Ok
    • Journal of the Korea Society of Computer and Information
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    • v.19 no.2
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    • pp.161-171
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    • 2014
  • In this paper the flow dynamics of the flue gas equipment in the desulfurization system was numerically analyzed by simulating the problems for the turbulent and combustion flow from Induced Draft Fan(I.D.Fan) outlet to Booster Up Fan(B.U.Fan) inlet using the commercial CFD software of CFD-ACE+ in CFDRC company for Computational Fluid Dynamic Analysis. The guide vane of this section was examined for the minimum pressure loss and the uniform flow dynamic to B.U.Fan with the proper velocity from I.D,Fan exit to B,U,Fan inlet section at the boiler both the maximum continuous rating and the design base. The guide vanes at I,D.Fan outlet and B.U.Fan inlet were removed and modified by numerical simulation of the CFD analysis. The flue gas at the system had the less pressure loss and the uniform flow dynamics of the flow velocity and flow line by comparing with the old design equipment.

Changes in Susceptibility of Killifish (Oryzias latipes) to Three Pesticides with Growth (농약에 대한 송사리 생육단계별 감수성의 변화)

  • Shin, Chun-Chul;Lee, Sung-Kyu;Kim, Young-Bae;Kim, Young-Hwa;Roh, Jung-Koo
    • Korean Journal of Environmental Agriculture
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    • v.6 no.1
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    • pp.50-60
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    • 1987
  • Sensitivity, expressed in the $96h-LC_{50}$ determined with continuous flow system, was compared for eight developmental stages of Oryzias latipes with butachlor, diazinon and fenitrothion. Significance of the laboratory determined $96h-LC_{50}$ in real field situation was evaluated for butachlor using outdoor model agrosystem. In the laboratory tests, the most sensitive stage was post-larva stage IV(7 days after hatching) with $96h-LC_{50}$ of 0.14, 1.4, and 1.6ppm for butachlor, diazinon and fenitrothion, respectively, whereas the least sensitive stage was early embryo stage(1 day after fertilization), and then the susceptibility was somewhat stable after 21days after hatching. In the model agrosystem test, the highest concentration of 0.53ppm of butachlor in water was obtained at the 2nd day after application. The stages IV and VIII showed mortality of over 50% at 96 hours after application. It is concluded that the conventional use of butachlor in the field would cause significant adverse effect on O. latipes. It is suggested that sensitivity test at the early life stages with fish is an important part of the ecotoxicological assessment of chemicals.

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Development of Long Term Flow Duration Curves for the Management of Total Maximum Daily Loads - in the Nakdong River Basin - (수질오염총량관리 단위유역 장기유황곡선 구축 -낙동강수계를 대상으로-)

  • Kim, Gyeong hoon;Kwon, Heon gak;Ahn, Jung min;Kim, Sanghun;Im, Tae hyo;Shin, Dong seok;Jung, Kang-Young
    • Journal of Environmental Science International
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    • v.26 no.8
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    • pp.939-953
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    • 2017
  • For the development of flow duration curves for the management of 41 Total Maximum Daily Load (TMDL) units of the Nakdong River basin, first, an equation for estimating daily flow rates as well as the level of correlation (correlation and determination coefficients) was extrapolated through regression analysis of discrete (Ministry of Environment) and continuous (Ministry of Land, Infrastructure and Transportation) measurement data. The equation derived from the analysis was used to estimate daily flow rates in order to develop flow duration curves for each TMDL unit. By using the equation, the annual flow duration curves and flow curves, for the entire period and for each TMDL unit of the basin, were developed to be demonstrated in this research. Standard flow rates (abundant-, ordinary-, low- and drought flows) for major flow duration periods were calculated based on the annual flow duration curves. Then, the flow rates, based on percentile ranks of exceedance probabilities (5, 25, 50, 75, and 95%), were calculated according to the flow duration curves for the entire period and are suggested in this research. These results can be used for feasibility assessment of the set values of primary and secondary standard flow rates for each river system, which are derived from complicated models. In addition, they will also be useful for the process of implementing TMDL management, including evaluation of the target level of water purity based on load duration curves.

Implantable Drug Delivery Systems-Design Process

  • Vincent, Croquet;Benolt, Raucent;Onori, Mauro
    • International Journal of Precision Engineering and Manufacturing
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    • v.7 no.4
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    • pp.40-46
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    • 2006
  • The market of programmable implantable pumps has bound to a monopolistic situation, inducing high device costs, thus making them inaccessible to most patients. Micro-mechanical and medical innovations allow improved performances by reducing the dimensions. This affects the consumption and weight, and, by reducing the number of parts, the cost is also affected. This paper presents the procedure followed to design an innovative implantable drug delivery system. This drug delivery system consists of a low flow pump which shall be implanted in the human body to relieve pain. In comparison to classical known solutions, this pump presents many advantages of high interest in both medical and mechanical terms. The first section of the article describes the specifications which would characterize a perfect delivery system from every points of view. This concerns shape, medication, flow, autonomy, biocompatibility, security and sterilization ability. Afterwards, an overview of existing systems is proposed in a decisional tree. Positive displacement motorized pumps are classified into three main groups: the continuous movement group, the fractioned translation group and the alternative movement group. These systems are described and the different problems which are specific to these mechanisms are presented. Since none of them fully satisfy the specifications, an innovation is justified.. The decisional tree is therefore extended by adding new principles: fractioned refilling and fractioned injection within the fractioned translation movement group, spider guiding system within the alternative translation movement group, rotational bearing guided device and notch hinge guided device in the alternative rotation movement group.

Continuos-Flow culture of Hepatocytes in Sugar-derivatized poly (lactide-co-glycolide) Scaffolds Prepared by Gas-foaming/salt-leaching Method

  • Yun, Jun-Jin;Park, Tae-Gwan
    • 한국생물공학회:학술대회논문집
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    • 2000.04a
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    • pp.141-144
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    • 2000
  • Highly open porous polymer matrices are required for high density cell seeding, efficient nutrient, and oxygen supply to the cells cultured in the three dimensional matrices. However, there are severe problems of mass transfer limitations within the cell/scaffolds culture system. Thus we hypothesize that continuos-flow culture conditioning of cells with the scaffolds may improve the cell viability and the differentiated function. In this study, we fabricated porous PLGA scaffolds by using gas-foaming/salt-leaching method as previous described. Viscous PLGA gel paste contains ammonium bicarbonate particulates, acting as a gas-foaming agent as well as a salt-leaching porogen, were cast into Teflon mold and dried. Ammonium bicarbonate salt upon contact to an acidic aqueous solution evloves gaseous ammonia and carbon dioxide by itself. And we conjugated galactose moiety [AGA; $N-(aminobuty1)-O-{\beta}-D-galactopyranosyl-(1{\rightarrow}4)-D-glucoamide]$ to the terminal end group of a PLGA to increase the cell adhesion and matain the differentiated function of hepatocytes. Cell-seeded scaffolds were secured in a flow bioreactor chamber and exposed to continuous flow at 5 ml/min. As a result of our study, the high yield of hepatocytes attachment was accomplished by increasing the concentration of PLGA-AGA conjugate in polymer scaffolds and cells in the scaffolds under continuos flow condition maintained a high level of viability and albumin secretion rate of cultured hepatocytes showed a higher level that of control groups.

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