• Title/Summary/Keyword: Continuous flow

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Cerebroprotective Effect of Nociceptin on Transient Focal Cerebral Ischemia in Rats

  • Lee Seung Yoon;Lee Won Suk;Choi Chang Hwa
    • Biomedical Science Letters
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    • v.11 no.2
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    • pp.201-209
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    • 2005
  • This study aimed to investigate the cerebroprotective effect of nociceptin on transient focal cerebral ischemia in Sprague-Dawley rats by determining the changes in regional cerebral blood flow (rCBF) and the infarct size. Right middle cerebral artery (MCA) was occluded for 2 hours, and thereafter was followed by reperfusion by an intraluminal monofilament technique. An open cranial window was made on the right parietal bone for determination of continuous changes in rCBF by laser-Doppler flowmetry. The infarct size was morphometrically determined using the 2,3,5-triphenyltetrazolium chloride technique. In normal rats, nociceptin ($0.01\~100\;nmol/kg$, Lv.) increased rCBF and decreased cerebral arterial resistance in a dose-dependent manner. Systemic arterial blood pressure was little affected by nociceptin at the doses of 0.01 and 0.1nmol/kg, but dose-dependently reduced at the doses of 1 nmol/kg or more. In transient cerebral ischemic rats, nociceptin ($0.01\~0.1$ nmol/kg, i.p.) significantly attenuated the postischemic cerebral hyperemia, and progressively increased rCBF. The improving effect of nociceptin on the postischemic rCBF response was markedly blocked by pretreatment with $[Nphe^1]nociceptin(1-13)NH_2$ (1 nmol/kg, i.p.), a selective nociceptin receptor antagonist, but not by naloxone ($3{\mu}mol/kg$, i.p.), a selective opioid receptor antagonist. The cerebral infarct size was significantly reduced by nociceptin ($0.01\~0.1$ nmol/kg) administered i.p. 5 min after MCA occlusion in transient cerebral ischemia of 2-hour MCA occlusion and 22-hour reperfusiion. It is suggested that nociceptin improves the postischemic cerebral hemodynamics and thereby has a cerebroprotective effect in transient focal cerebral ischemia.

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A Study on the Continuity Expressed in Modern Fashion Design - Focusing on the Continuance Theory of H. Bergson and the Continuity theory of J. Deleuze - (현대 패션 디자인에 나타난 연속성 연구 - 베르그송의 지속 이론과 들뢰즈의 연속성 이론을 중심으로 -)

  • Yang, Hee-Young;Yang, Sook-Hi
    • Journal of the Korean Society of Costume
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    • v.58 no.2
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    • pp.15-33
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    • 2008
  • Continuity and discontinuity is a relative concept, and there are various categories of the continuity and discontinuity in our circumference. Generally, characteristics of postmodernism including between the difference and the variety have being regarded as a discontinuity. Concept of the continuity includes between the quantitative continuity and the qualitative continuity qualitative continuity has organic characteristic, which encourages creating something permanently through the flowing of the time. Therefore, this thesis has studied like this complex social condition and various relationships expressed in modern fashion focusing on permanently creative movements and behaviors equal to the 'continuance' theory of Herni Bergson and 'continuity' theory of Jill Deleuze. This thesis classifies characteristics of the qualitative continuity into spatiotemporal and spatial continuity, and subdivides into 3 sets: perceptual continuity, spatial continuity, transferring continuity of physical experience, immaterial informational continuity, and fluid continuity with environment. Continuous viewpoint, which accepts the existing elements and allows them to flow liberally, should be present more appropriative thinking direction in explaining the complex situation expressed in the modern fashion, rather than discontinuous viewpoints focused on the only changing moment.

Characteristics of Non-point Source Runoff in Housing and Industrial Area during Rainfall (강우시 주택 및 공단지역의 비점오염원 유출특성)

  • Kim, Kang Suk;Park, Jong Seok;Hong, Hyeon Seung;Rhee, Kyoung Hoon
    • Journal of Wetlands Research
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    • v.14 no.4
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    • pp.581-589
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    • 2012
  • Non-point source pollutant is exerting a serious influence on the water quality, since the characteristics of stormwater runoff is varied by the land usage pattern of an area and a basin, and all sorts of pollutants on the earth in rainfall flow into the urban stream. This study estimated EMC of each pollutant to investigate the characteristics of stormwater runoff by separating the urban area as the housing area and industrial area. As a result of the analysis, the first flush effect occurred in the non-point source pollutant of housing area and industrial area, as the runoff concentration gradually reduces after it rapidly increases in the initial rainfall, and in case of the non-point source pollutant the control of first stage rain-water. It is considered to require the continuous follow-up study such as the scale of long-term rainfall event and water quality data, land usage pattern by GIS method, database of topography and geological features, and so forth.

Process Algebra Based Formal Method for SDN Application Verification (SDN 응용 검증을 위한 프로세스 알지브라 기반 정형 기법)

  • Shin, Myung-Ki;Yi, Jong-Hwa;Choi, Yunchul;Lee, Jihyun;Lee, Seung-Ik;Kang, Miyoung;Kwak, Hee Hwan;Choi, Jin-Young
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39B no.6
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    • pp.387-396
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    • 2014
  • Recently, there have been continuous efforts and progresses regarding the research on diverse network control and management platforms for SDN (Software Defined Networking). SDN is defined as a new technology to enable service providers/network operators easily to control and manage their networks by writing a simple application program. In SDN, incomplete or malicious programmable entities could cause break-down of underlying networks shared by heterogeneous devices and stake-holders. In this sense, any misunderstanding or diverse interpretations should be completely avoided. This paper proposes a new framework for SDN application verification and a prototype based on the formal method, especially with process algebra called pACSR which is an extended version of Algebra of Communicating Shared Resources (ACSR).

Bi-axial texture analysis of Ni substrate for superconducting coated conductor using R2R XRD (R2R XRD를 이용한 초전도박막선재용 기판의 이축배향 특성 분석)

  • Ha, Hong-Soo;Yang, Ju-Saeng;Kim, Ho-Sup;Ko, Rock-Kil;Song, Kyu-Jung;Ha, Dong-Woo;Oh, Sang-Soo;Joo, Jin-Ho
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2005.11a
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    • pp.22-23
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    • 2005
  • In order to increase the critical current of coated conductor, highly Bi-axially textured substrates are required. Texture uniformity of substrate is also important to fabricate high quality superconducting coated conductor because the amount of current flow along the coated conductor is limited by the defects such as bad textured area. Therefore, we need to evaluate the distribution of texture of Ni substrate along the length before buffer layer deposition on Ni tape. R2R(reel-to-reel) XRD system was used to measure the texture of long Ni substrate continuously. $\theta-2\theta$ scan of 10 m long Ni tape was measured and indicates that some of Ni(111) planes equally remain on Ni(002) textured substrate. The results of continuous Ni(220) $\Phi$-scan indicate that average FWHM is 9$^{\circ}$ within $\pm$1.

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Implementation of Location-Aware VOD Service supporting User Mobility in Ubiquitous Spaces (편재형 공간에서 사용자 이동성을 지원하는 위치 인식 VOD서비스의 구현)

  • Choi Tae Uk;Chung Ki Dong
    • Journal of KIISE:Information Networking
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    • v.32 no.1
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    • pp.80-88
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    • 2005
  • In ubiquitous spaces, a user wants to be provided with a VOD service while moving one space to another freely. Since the traditional VOD system is dependent on user location, the VOD server transmits video data to a single client during a session. If the user moves to another space, he/she should close the old session and make a new request for the same video. However, the location-aware VOD system supports user mobility by closing and opening the session automatically. That is, the VOD system automatically perceives the movement of a user and allows the server to change the data flow so that a client near the user can receive the video data. This paper proposes a location-aware VOD service architecture and a session handoff scheme to provide a mobile user with continuous video delivery and implements a location-aware VOD prototype system based on Jini and Java. In experiment, we show that the proposed handoff scheme has a smaller handoff delay than the other handoff scheme.

Is Early Spinal Cord Stimulation in Patients with Complex Regional Pain Syndrome Necessary? -A case report- (복합부위통증증후군 제I형 환자에서 조기 척수자극술이 필요한가? -증례보고-)

  • Min, Hyoung Ki;Han, Kyung Ream;Lee, Sang Eun;Kim, Kyoung Tae;Kim, Chan
    • The Korean Journal of Pain
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    • v.19 no.2
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    • pp.223-227
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    • 2006
  • Complex regional pain syndrome (CRPS) is clinically characterized by pain, abnormal regulation of blood flow and sweating, edema of skin and subcutaneous tissues, sensory and motor disturbances, and trophic changes of the skin. A 21-year-old man was suffering from pain and swelling in his right hand and forearm. His arm had been in splints for 3 weeks following an extension injury of the right fingers and wrist, with the pain having developed 2 weeks after the splinting. He was treated with various nerve blocks including continuous epidural infusion, thoracic sympathetic block and peripheral nerve blocks, and squeezing his edematous region under general anesthesia as well as intravenous lidocaine and ketamine infusions. However, all of the performed treatments had no effect on the patient's pain or hand swelling. As a next line therapy, spinal cord stimulation should be considered because of intractable severe pain and swelling to almost all other modalities of therapy. We therefore performed an early intervention of spinal cord stimulation for the patient with refractory CRPS type I 5 months after the onset of pain and have got an excellent result.

Effect of Zinc on the Suspended Growth Biological Wastewater Treatment (부유 성장식 생물학적 폐수처리에 미치는 아연의 영향)

  • Seo, Jeong-Beom;Hwang, Chang-Min
    • Journal of Korean Society of Environmental Engineers
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    • v.37 no.4
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    • pp.228-233
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    • 2015
  • This study was performed to examine the effect of zinc on the biodegradability, nitrification, denitrification and oxygen uptake rate (OUR) using batch reactor and continuous flow stirred tank reactor (CSTR) of anaerobic/anoxic/oxic ($A^2/O$). The results of this study can be summarized as follows. In the case of the effect of zinc on organic treatment, zinc had no effect up to 12 mg/L with batch reactor but biodegradability was lowered when it was above 3.0 mg/L with CSTR. Concerning the case on nitrification and removal of nitrogen, nitrification rate was lowered when zinc was above 6.0 mg/L with batch reactor and removal rate of nitrogen was lowered when zinc was above 3.0 mg/L with CSTR. Removal rate of phosphorus was lowered when it was above 6.0 mg/L zinc with batch reactor and above 3.0 mg/L zinc with CSTR. In the case of OUR, it decreased as microbial activity was affected when zinc concentration was above 3.0 mg/L in CSTR.

Phenol Removal Using Horseradish Peroxidase(HRP)-Mediated Polymerization Reaction in Saturated Porous Media (다공성 포화 매질에서 효소 중합반응을 이용한 페놀 제거)

  • Kim, Won-Gee;Lee, Seung-Mok
    • Journal of Korean Society of Environmental Engineers
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    • v.30 no.10
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    • pp.984-991
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    • 2008
  • This paper reports experimental results, demonstrating the feasibility of horseradish peroxidase(HRP) and H$_2$O$_2$ to reduce phenol transport in saturated porous media. A laboratory-scale packed column reactor(ID: 4.1 cm, sand-bed height 12 cm) column was utilized to simulate injection of HRP and H$_2$O$_2$ into an aquifer contaminated with phenol. Effluent concentrations of phenol and polymerization products were monitored before and after enzyme addition under various experimental conditions(enzyme dose: 0$\sim$2 AU/mL, [ionic strength]: 5$\sim$100 mM, pH: 5$\sim$9). The concentration of phenol in the column effluent was found to decrease by nearly 90% in the presence of HRP(2 AU/mL) and H$_2$O$_2$ in the continuous flow system at pH 7 and ionic strength 20 mM. The influent phenol was converted in the system to insoluble precipitate, which deposited in pore spaces. The remains were discharged as soluble oligomers. About 8% of total pore volume in column system was decreased by deposition of polymer produced.

Sediment Distribution of the Yeosu Sound on the Southern Coast of Korea Based on the 3.5 kHz Profiles (3.5 kHz 지층단면도에 나타난 여수해만의 퇴적물 분포)

  • 오진용;이연규;윤혜수;김성렬;최정민
    • Economic and Environmental Geology
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    • v.33 no.5
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    • pp.425-434
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    • 2000
  • The 3.5 KHz seismic survey was carried out for studying the distribution pattern of the unconsolidated sediments of the Yeosu Sound on the southern coast of the Korean Peninsula. Field data originally recorded in analog are converted and processed digitally to recover the high-resolution acoustic profiles. Across the north-south trending channel with the depth of 20~30 m, different seismic facies types are observed in the top section of sediments. The western part is characterized by the continuous high-amplitude subparallel reflectors within which the acoustic turbidity as a token of the presence of gas is commonly observed, whereas the counterpart largely shows poor reflectors and has shallow acoustic basement toward the north. The dissimilarity of the seismic expression across the channel can be interpreted as the result of the change of depositional environment caused by relative sea-level fluctuations of the late-Quaternary. During the last glacial period, the Yeosu Sound was exposed and eroded by the paleo-Seomjin River. By the following rapid rise of sea level, it was covered by the transgressive sand sheet. When the sea level reached near the present position, the muddy sediment has accumulated only in the western part of the Yeosu Sound as its depositional front has moved toward the north. It is partly caused by the asymmetrical tidal current in the Yeosu Sound where the flood near the bottom has stronger current flow and contains more suspended sediments.

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