• 대한음성학회:학술대회논문집
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• 대한음성학회 2003년도 5월 학술대회지
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• pp.75-78
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• 2003

In this paper, we describe a cross-morpheme pronunciation variation model which is especially useful for constructing morpheme-based pronunciation lexicon for Korean LVCSR. There are a lot of pronunciation variations occurring at morpheme boundaries in continuous speech. Since phonemic context together with morphological category and morpheme boundary information affect Korean pronunciation variations, we have distinguished pronunciation variation rules according to the locations such as within a morpheme, across a morpheme boundary in a compound noun, across a morpheme boundary in an eojeol, and across an eojeol boundary. In 33K-morpheme Korean CSR experiment, an absolute improvement of 1.16％ in WER from the baseline performance of 23.17％ WER is achieved by modeling cross-morpheme pronunciation variations with a context-dependent multiple pronunciation lexicon.

• 한국언어정보학회지:언어와정보
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• 제14권1호
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• pp.1-24
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• 2010

The complexity of comparative constructions in each language has given challenges to both theoretical and computational analyses. This paper first identifies types of comparative constructions in Korean and discusses their main grammatical properties. It then builds a syntactic parser couched upon the typed feature structure grammar, HPSG and proposes a context-dependent interpretation for the comparison. To check the feasibility of the proposed analysis, we have implemented the grammar into the existing Korean Resource Grammar. The results show us that the grammar we have developed here is feasible enough to parse Korean comparative sentences and yield proper semantic representations though further development is needed for a finer model for contextual information.

• Molecules and Cells
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• 제43권7호
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• pp.591-599
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• 2020

Complex cell-to-cell communication underlies the basic processes essential for homeostasis in the given tissue architecture. Obtaining quantitative gene-expression of cells in their native context has significantly advanced through single-cell RNA sequencing technologies along with mechanical and enzymatic tissue manipulation. This approach, however, is largely reliant on the physical dissociation of individual cells from the tissue, thus, resulting in a library with unaccounted positional information. To overcome this, positional information can be obtained by integrating imaging and positional barcoding. Collectively, spatial transcriptomics strategies provide tissue architecture-dependent as well as position-dependent cellular functions. This review discusses the current technologies for spatial transcriptomics ranging from the methods combining mechanical dissociation and single-cell RNA sequencing to computational spatial re-mapping.

• Clinical and Experimental Pediatrics
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• 제55권1호
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• pp.6-10
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• 2012

Human puberty is a complex, coordinated biological process with multiple levels of regulations. The timing of puberty varies greatly in children and is influenced by both environmental and genetic factors. The key genes of pubertal onset, $KISS1$, $GPR54$, $GNRH1$ and $GNRHR$, may be major causal factors underlying gonadotropin-releasing hormone-dependent precocious puberty (GDPP). Two gain-of-function mutations in $KISS1$ and $GPR54$ have been identified recently as genetic causes of GDPP. $GNRH1$ and $GNRHR$ are also gene candidates for GDPP; however no mutations have been identified in these genes. Presently potential genetic causes like $LIN28B$ continues to appear; many areas of research await exploration in this context. In this review, I focus primarily on the genetic causes of GDPP.

• Anatomy and Cell Biology
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• 제56권1호
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• pp.16-24
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• 2023

Endothelial cells (EC) are the anatomical boundaries between the intravascular and extravascular space. Damage to ECs is catastrophic and induces endothelial cell dysfunction. The pathogenesis is multifactorial and involves dysregulation in the signaling pathways, membrane lipids ratio disturbance, cell-cell adhesion disturbance, unfolded protein response, lysosomal and mitochondrial stress, autophagy dysregulation, and oxidative stress. Autophagy is a lysosomal-dependent turnover of intracellular components. Autophagy was recognized early in the pathogenesis of endothelial dysfunction. Autophagy is a remarkable patho (physiological) process in the cell homeostasis regulation including EC. Regulation of autophagy rate is disease-dependent and impaired with aging. Up-regulation of autophagy induces endothelial cell regeneration/differentiation and improves the function of impaired ones. The paper scrutinizes the molecular mechanisms and triggers of EC dysregulation and current perspectives for future therapeutic strategies by autophagy targeting.

• Structural Engineering and Mechanics
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• 제90권5호
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• pp.459-466
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• 2024

Eringen's nonlocal thermoelasticity theory is used to study wave propagations in a rotating two-temperature thermoelastic half-space with temperature-dependent properties. Using suitable non-dimensional variables, the harmonic wave analysis is used to convert the partial differential equations to ordinary differential equations solving the problem. The modulus of elasticity is given as a linear function of the reference temperature. MATLAB software is used for numerical calculations. Comparisons are carried out with the results in the context of the dual-phase lag model for different values of rotation, a nonlocal parameter, an inclined load, and an empirical material constant. The distributions of physical fields showed that the nonlocal parameter, rotation, and inclined load have great effects. When a nonlocal thermoelastic media is swapped out for a thermoelastic one, this approach still holds true.

• Journal of applied mathematics & informatics
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• 제2권2호
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• pp.21-46
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• 1995

Congestion and memory occupancy in computer system may be reduced further if new jobs are admitted only when the num-ber of jobs queued at CPU is below CPU run queue cutoff (RQ). In this paper we prove that response time of a job is invariant with respect to RQ if jobs do not communicate each other. We also demonstrate this invariance property numerically using marix-geometric methods and present an approximate method for the delay due to context switch-ing under time slicing. The approximation suggests that time slicing with constant overhead yields a throughput similar to an FCFS system without overhead.

• Journal of Astronomy and Space Sciences
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• 제15권1호
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• pp.65-68
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• 1998

We construct the X-ray light curves of the W UMa type contact binary SS Arietis(HD12929) from the EXOSAT data in HEASARC data archive. The phase dependent X-ray light curves obtained by using the ephimeris of Kaluzny & Pojmanski of SS Ari is modulated on the orbital phase as in the case of other W UMa type binaries. Although a detailed analysis of these data is impossible because of the very low X-ray light curves in the context of the radiation in the corona region of W UMa type stars.

• 한국동물학회:학술대회논문집
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• 한국동물학회 2003년도 한국생물과학협회 학술발표대회
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• pp.196.1-196
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• 2003

No Abstract, See Full Text

• Journal of the Korean Statistical Society
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• 제31권3호
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• pp.343-357
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• 2002

This paper proposes a method for producing smooth and positive estimates of the intensity function of an inhomogeneous Poisson process based on the shrinkage of wavelet coefficients of the observed counts. The information projection is used in conjunction with the level-dependent thresholds to yield smooth and positive estimates. This work is motivated by and demonstrated within the context of a problem involving gamma-ray burst data in astronomy. Simulation results are also presented in order to show the performance of the information projection estimators.