• 한국정보처리학회논문지
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• 제7권12호
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• pp.3874-3884
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• 2000

정보검색시스템은 색인어와 질의어가 정확히 일치하지 않더라도 사용자 질의에 적합한 문서를 검색할 수 있어야 한다. 그러나, 색인어와 질의어간의 용어 불일치는 검색성능의 개선에 심각한 장애요소로 작용해 왔다. 따라서, 본 논문에서는 문서 코퍼스의 단어들간에 자동 용어 정규화를 수행하고, 용어 정규화의 산물을 한국어 정보검색 시스템에 적용하는 방안을 제시한다. 용어 불일치를 완화하기 위해 두가지 용어 정규화, 동치부류와 공기단어 클러스터를 수행한다. 첫째, 음역어, 절차오류, 그리고 동의어를 위해 문맥 유사도를 이용하여 동치부류로 구축하는 작업이다. 둘째, 상호정보와 단어 문맥의 조합을 이용하여 단어 유사도를 계산하고 문맥 기반 용어를 정규화한다. 그런 다음, K-means 알고리즘을 이용하여 자율 클러스터링을 수행하고 공기단어 클러스터를 구축한다. 본 논문에서는 이러한 용어 정규화의 산물들을 용어 불일치를 완화하기 위해 질의어 확장과정에서 사용한다. 다시 말해서 동치부류와 공기단어 클러스터는 새로운 용어로 질의를 확장하는 자원으로서 사용된다. 이러한 질의확장으로 사용자는 질의어에 음역어를 추가하여 질의어를 포괄적으로 만들거나 특정어를 추가하여 질의어를 세밀하게 만들 수 있다. 질의어 확장을 위해 두 가지 상호보완적인 방법인 용어 제시와 용어 적합성 피드백을 이용한다. 실험 결과는 제안된 시스템이 의미적 용어 불일치를 완화할 수 있고, 적절한 유사도 값을 제공할 수 있음을 보여준다. 결과적으로 제안한 시스템이 정보 검색 시스템의 검색 효율을 향상시킬 수 있음을 알 수 있다.

• International Journal of Computer Science & Network Security
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• 제21권8호
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• pp.71-78
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• 2021

The relevance of research provides the necessity to identify the basic problems in the public governance sphere and information technology relations, forasmuch as understanding such interconnections can indicate the consequences of the development and spreading information technologies. The purpose of the research is to outline the issues of applying information technologies in public governance sphere. 500 civil servants took part in the survey (Ukraine). A two-stage study was conducted in order to obtain practical results of the research. The first stage involved collecting and analyzing the responses of civil servants on the Mentimeter online platform. In the second stage, the administrator used the SWOT-analysis system. The tendencies in using information technologies have been determined as follows: the institutional support development; creation of analytical portals for ensuring public control; level of accountability, transparency, activity of civil servants; implementation of e-government projects; changing the philosophy of electronic services development. Considering the threats and risks to the public governance system in the context of applying information technologies, the following aspects generated by societal requirements have been identified, namely: creation of the digital bureaucracy system; preservation of information and digital inequality; insufficient level of knowledge and skills in the field of digital technologies, reducing the publicity of the state and municipal governance system. Weaknesses of modern public governance in the context of IT implementation have been highlighted, namely: "digitization for digitalization"; lack of necessary legal regulation; inefficiency of electronic document management (issues caused by the imperfection of the interface of reporting interactive forms, frequent changes in the composition of indicators in reporting forms, the desire of higher authorities to solve the problem of their introduction); lack of data analysis infrastructure (due to imperfections in the organization of interaction between departments and poor capacity of information resources; lack of analytical databases), lack of necessary digital competencies for civil servants. Based on the results of SWOT-analysis, the strengths have been identified as follows: (possibility of continuous communication; constant self-learning); weaknesses (age restrictions for civil servants; insufficient acquisition of knowledge); threats (system errors in the provision of services through automation); opportunities for the introduction of IT in the public governance system (broad global trends; facilitation of the document management system). The practical significance of the research lies in providing recommendations for eliminating the problems of IT implementation in the public governance sphere outlined by civil servants..

• 정보처리학회논문지B
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• 제12B권6호
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• pp.697-702
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• 2005

주제 중심 웹 문서 수집기는 검색엔진에서 최신의 웹 문서 색인을 유지하는 대안방안으로 부상하고 있다. 그러나 주제 중심 웹 문서 수집기는 비 관심문서에서 연결된 관심문서들을 수집할 수 없는 문제점을 가지고 있다. 이러한 문제점은 문서의 구조적 특징을 고려하지 않아서 발생한다. 특히 문서분석 방법인 문서의 발생 횟수 및 역문헌 발생빈도는 이러한 문제를 야기하는 주요 원인이 된다 주제 중심 웹 문서 수집기의 성능을 향상하기 위해서 본 논문에서는 국소 정보기반의 문서 분할법을 제안한다. 본 논문에서는 문서를 하이퍼링크 주변의 문맥을 고려한 특징 정보들을 사용하여 여러 소각의 문서로 나눈다. 본 논문에서 제안하는 주제 중심 웹 문서 수집기는 나누어진 문서들을 이용하여 하이퍼링크가 관심문서를 가리키는 것인지를 판단하여 문서를 수집할 것인지를 판단한다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.3735-3740
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• 2015

Context: Insulin-like growth factor peptides play important roles in regulating cell growth, cell differentiation, and apoptosis, and have been demonstrated to promote the development of colorectal cancer (CRC). Objective: To examine the association of insulin-related biomarkers including insulin-like growth factor-1 (IGF-1), insulin-like growth factor binding protein-3 (IGFBP-3) and C-peptide with CRC risk and assess their relevance in predictive models. Materials and Methods: The odds ratios of colorectal cancer for serum levels of IGF-1, IGFBP-3 and C-peptide were estimated using unconditional logistic regression models in 100 colorectal cancer cases and 100 control subjects. Areas under the receiving curve (AUC) and integrated discrimination improvement (IDI) statistics were used to assess the discriminatory potential of the models. Results: Serum levels of IGF-1 and IGFBP-3 were negatively associated with colorectal cancer risk (OR=0.07, 95%CI: 0.03-0.16, P for trend <.01, OR=0.06, 95%CI: 0.03-0.15, P for trend <.01 respectively) and serum C-peptide was positively associated with risk of colorectal cancer (OR=4.38, 95%CI: 2.13-9.06, P for trend <.01). Compared to the risk model, prediction for the risk of colorectal cancer had substantially improved when all selected biomarkers IGF-1, IGFBP-3 and inverse value of C-peptide were simultaneously included inthe reference model [P for AUC improvement was 0.02 and the combined IDI reached 0.166% (95 % CI; 0.114-0.219)]. Conclusions: The results provide evidence for an association of insulin-related biomarkers with colorectal cancer risk and point to consideration as candidate predictor markers.

• 의학교육논단
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• 제18권3호
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• pp.125-131
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• 2016

Recent changes in educational paradigms that emphasize the performance or outcomes of education are redefining how learning objectives are being described as 'learning outcomes' in various academic disciplines. Medical education is not an exception to this trend. However, it has come to our attention that the key concepts and appropriate descriptions of learning outcomes have not been well understood among educators and that this lack of understanding has hindered our efforts to implement the practice in the field. This study aims to provide a direction to establish and describe learning outcomes by examining previous studies that have focused on setting learning objectives as well as learning outcomes. Setting and describing learning outcomes starts from reflection on the approach of behavioral learning objectives, which overemphasizes learner's acquired knowledge, skills, and attitude in each classroom rather than actual performance. On the other hand, the learning outcome approach focuses on what the learner is able to do as a result of a learning experience. This approach is more learner-friendly and encourages students to lead and be responsible for their learning process. Learning outcomes can best be described when the relevance of actual contexts and the hierarchy of learning objectives are considered. In addition, they should be in the form of context, task, performance, and level, as well as be planned with proper assessment and feedback procedures. When these conditions are met, the learning outcome approach is beneficial to students as it presents a curriculum that is more open to learners. Despite these advantages of the learning outcome approach, there is a possible concern that setting the learning outcomes and describing them can restrict evaluation to lower cognitive skills if the concept of learning outcome is narrowly interpreted or is set too low. To avoid such narrow applications, it is important for educators to understand the comprehensiveness of the learning outcome setting and to consider long-term outcomes embedded in an organizational vision rather than only short-term behavioral outcomes.

• 한국지역지리학회지
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• 제23권2호
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• pp.257-268
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• 2017

우리나라 대표적인 임해형 산업지역으로 기능하고 있는 광양만권에 있는 여수시 순천시 광양시는 단일 생활권 도시권 경제권을 형성하고 있다. 이런 지역적 여건에서 일부 상공인과 전문가들이 3개 도시의 연합체 논의를 추동하고 있다. 이 연구는 광양만권 도시연합을 전문가 집단은 어떻게 인식 평가하는가를 분석한 것이다. 전문가 집단은 광양만권 발전 잠재력을 높게 인식하였고, 도시연합 타당성도 매우 긍정적으로 평가하였다. 여수 순천 광양의 도시연합에는 약 8.3년 정도 소요될 것으로 추정하였다. 도시연합을 성사시키기 위해서는 광양만권 발전 비전의 공유, 도시연합을 위한 주민의 이해와 동의가 선행 과제로 도출되었다.

• Journal of Microbiology and Biotechnology
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• 제26권6호
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• pp.999-1010
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• 2016

Ganoderma lucidum BCCM 31549 has a long established role for its therapeutic activities. In this context, much interest has focused on the possible functions of the (1,3)-β-D-glucan (G) produced by these cultures in a stirred-tank bioreactor and extracted from their underutilized mycelium. In the existing study, we report on the systematic production of G, and its sulfated derivative (GS). The aim of this study was to investigate G and its GS from G. lucidum in terms of their antibacterial properties and cytotoxicity spectrum against human prostate cells (PN2TA) and human caucasian histiocytic lymphoma cells (U937). ¹H NMR for both G and GS compounds showed β-glycosidic linkages and structural similarities when compared with two standards (laminarin and fucoidan). The existence of characteristic absorptions at 1,170 and 867 cm^-1 in the FTIR (Fourier Transform Infrared Spectroscopy) for GS demonstrated the successful sulfation of G. Only GS exhibited antimicrobial activity against a varied range of test bacteria of relevance to foodstuffs and human health. Moreover, both G and GS did not show any cytotoxic effects on PN2TA cells, thus helping demonstrate the safety of these polymers. Moreover, GS showed 40% antiproliferation against cancerous U937 cells at the low concentration (60 μg/ ml) applied in this study compared with G (10%). Together, this demonstrates that sulfation clearly improved the solubility and therapeutic activities of G. The water-soluble GS demonstrates the potential multifunctional effects of these materials in foodstuffs.

• International Journal of Computer Science & Network Security
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• 제21권9호
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• pp.323-331
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• 2021

The relevance of the study implies the need to explain the main determinants of environmental policy, allowing countries to converge on a common working basis. The purpose of the research is to explore ways in which the environmental aspects of EU regions and territories can be shaped to apply to domestic environmental policy. A total of 997 representatives from the Ukrainian UTCs, who are involved in local environmental policy, participated in the survey. Results of the research. A hierarchy of regional environmental policy objectives has been identified. Three key principles of eco-policy development have been distinguished. The means of the innovative approach strategy implementation have been outlined (formation of the regional market of environmental services; organization of interaction between environmental agencies and market structures; establishment of environmental funds which finance environmental activities; implementation of the "collateral return" system; formation of a system of benefits and loans to enterprises that successfully implement the environmental policy). The means of the prognostic approach implementation strategy to the development of the region's environmental policy have been determined (the use of an orderly and successful long-term strategy of economic development of the region; obligatory consideration in the mechanisms strategy aimed at improvement of environmental management system of the region, interbranch impact of the projects implemented on the region's ecological situation; taking into consideration the economic and geographical peculiarities of the region, the necessary infrastructure, issues of the territorial location of the large enterprises in the region and their impact on the environment). The means of the traditional approach strategy implementation have been outlined (activity programs focused on solution of specific problems, rather than on the implementation of measures for environmental restoration and enhancement; nature conservation problems have interbranch, interdepartmental character due to unity of the region's ecosystem; tracking complexity of changing conditions (water basins, woodlands, air-mass transport), regional boundaries generally do not coincide with natural ecosystems boundaries). The practical significance of the study lies in providing recommendations for the implementation of certain aspects of Ukrainian UTC's environmental policy.

• 한국자기공명학회논문지
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• 제23권1호
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• pp.20-25
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• 2019

The transcription factor CP2c has been recently validated as an oncogenic protein that can serve as a promising target for anticancer therapy. We have recently documented that a recombinant protein corresponding to the putative DNA-binding region (residues 63-244) of CP2c adopted two different conformers, one of which is dominated by zinc binding. However, in the present study, a longer construct encompassing residues 63-302 appeared to form a single structural domain. This domain could be considered to adopt a functionally relevant fold, as the known specific binding of a dodecapeptide to this protein was evident. Hence, the residues 63-302 region rather than 63-244 can be regarded as a natively folded structural domain of CP2c. In addition, it was confirmed that zinc ions can bind to this putative DNA-binding domain of CP2c, which resulted in reduced stability of the protein. In this context, it is suggested that the mode of action of CP2c would resemble that of tumor suppressor p53.

• International Journal of Computer Science & Network Security
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• 제21권6호
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• pp.304-311
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• 2021

The relevance of the research involves outlining the need for modern professionals to acquire new competencies. In the conditions of rapid civilizational progress, in order to meet the requirements of the labor market in the knowledge society, there is a readiness for continuous training as an indicator of professional success. The purpose of the research is to identify the impact of various forms of application of information technologies for lifelong learning in order to provide the continuous self-development of each person without cultural or age restrictions and on the basis of rapid digital progress. A high level (96%) of need of the adult population in continuing education with the use of digital technologies has been established. The most effective ways to implement the concept of "lifelong learning" have been identified (educational camps, lifelong learning, mass open online courses, Makerspace activities, portfolio use, use of emoji, casual game, scientific research with iVR game, implementation of digital games, work in scientific cafes). 2 basic objectives of continuing professional education for adults have been outlined (continuous improvement of qualifications and obtaining new qualifications). The features of ICT application in adult education have been investigated by using the following methods, namely: flexibility in terms of easy access to ideas, solving various problems, orientation approach, functional learning, group or individual learning, integration of leisure, personal and professional activities, gamification. The advantages of application of information technologies for continuous education (economic, time, and adaptive) have been revealed. The concept of continuous adult learning in the context of digitalization has been concluded. The research provides a description of the structural principles of the concept of additional education; a system of information requests of the applicant, as well as basic technologies for lifelong learning. The research indicates the lack of comprehensive research in the relevant field. The practical significance of the research results lies in the possibility of using the obtained results for a wider acquaintance of the adult population with the importance of the application of lifelong learning for professional activities and the introduction of methods for its implementation in the educational policy of the state.