• International Journal of Contents
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• 제6권3호
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• pp.10-14
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• 2010

Researchers in Korea and elsewhere have carried out a wide variety of important research activities in their respective fields, producing valuable research results. For such diverse research results to be shared and exchanged among researchers working in the same discipline and research subject there needs to be a community environment based on free utilization of information. Against this backdrop, this study seeks to classify and reprocess the reference/factual content owned by the KISTI (Korea Institute of Science and Technology Information), a state-run distributor of information on science and technology, by the different research subjects. It also seeks to develop and provide a community model based on the concepts of open archiving and open access for the researchers specialized in the related fields of research. This community model is developed focusing on the research results from the field of bioscience, where the most extensive studies are currently being conducted. To develop the community model, this study: (a) surveys the current status of the content owned by KISTI; (b) analyzes the patterns and characteristics of biological scientific content among the KISTI-owned content; and (c) designs a web platform where researchers can freely upload/download research results.

• 한국미생물·생명공학회지
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• 제47권2호
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• pp.195-200
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• 2019

The purpose of this study was to investigate the melanogenesis inhibiting activity of the ethanol extract from Polygonum amphibium L. Firstly, the n-hexane (Hx), chloroform ($CHCl_3$), ethyl acetate (EA), n-butanol (BuOH), and water (Water) fractions were isolated from the P. amphibium L. ethanol extract. The efficacy of melanogenesis was found to significantly decrease via the EA and BuOH fractions when compared to the control in B16F10 cells. EA particularly showed the lowest melanin content in B16F10 cells when compared to all the other extracts. Concentration-dependent inhibition of melanin synthesis was also observed in the EA fraction at concentrations below $50{\mu}g/ml$, which did not exhibit cytotoxicity in B16F10 cells. Notably, the expression of three key proteins (tyrosinase, tyrosinase-related protein-1 (TRP-1), and TRP-2), which are involved in melanogenesis, were significantly decreased via the EA fraction. EA also inhibited body pigmentation in vivo in a zebrafish model. Overall, we demonstrated melanogenesis suppression using the EA fraction from P. amphibium L., which could be a potential candidate for an antimelanogenesis agent.

• Journal of Nutrition and Health
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• 제30권10호
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• pp.1160-1169
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• 1997

The purpose of this research was to investigate the effects of caffeine and calcium levels on calcium utilization in female rats of different ages. Calcium utilization was compared in female rats of different age( 4 weeks and 12 months) fed various levels of caffeine(0 and 7 mg/100g body weight) and calcium (50, 100 and 200% of requirement) for 3 weeks. Feed intake of the caffeine groups were lower than that of the no-caffeine groups. body weight gain was lowest in the high-caffeine and low-calcium group. Serum calcium levels of young rats were higher than those of adult rats. There were no significant differences in tibial calcium content among the caffeine and calcium -groups. Fecal calcium excretion increased as the level of dietary calcium was increased. Urinary calcium excretion increased as the levels of caffeine and dietary calcium were increased. With increasing levels of dietary calcium , daily calcium retention was accelerated, but apparent calcium absorbability was diminished. The results of this study suggest that caffeine consumption promotes urinary calcium excretion. However, increase in dietary calcium resulted in higher calcium retention . These findings indicate that high caffeine consumption may increase dietary calcium requirements. Therefore, it could be suggested that the supplementation of dietary calcium may counteract the negative effect of caffeine intake on calcium utilization.

• 임상간호연구
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• 제18권1호
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• pp.159-170
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• 2012

Purpose: This study was designed to examine the validity of the evidence-based guideline on pain developed by Registered Nurses Association of Ontario(RNAO) translated into Korean based on the experts' opinions. Methods: The panel consisted of experts of 60 registered nurses in surgical units, medical doctors and nursing managers who were experts in pain assessment and management. The validity of translated RNAO guideline was evaluated in terms of appropriateness, applicability, and utilization in current practice. Appropriateness and applicability of each recommendation were measured with 9 point scale, whereas utilization was measured by yes/no question. Data were analyzed by mean, standard deviation, and percent. The experts' opinions were analyzed by content analysis method. Results: In general, most of the recommendations in the guideline received above 7 point in appropriateness and applicability. However, above 20% of recommendations showed less than 50% of utilization rates in current practice. Conclusion: The reasons for low utilization of recommendations in current practice are in need for investigation. This study can be used for the development of guideline more acceptable in Korean health care settings and improve the quality of care for the abdominal surgery patients suffering from pain in Korea.

• BMB Reports
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• 제46권1호
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• pp.31-36
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• 2013

Heat shock proteins play an important role in plant stress tolerance and are mainly regulated by heat shock transcription factors (Hsfs). In this study, we generated transgenic rice over-expressing OsHsfA7 and carried out morphological observation and stress tolerance assays. Transgenic plants exhibited less, shorter lateral roots and root hair. Under salt treatment, over-expressing OsHsfA7 rice showed alleviative appearance of damage symptoms and higher survival rate, leaf electrical conductivity and malondialdehyde content of transgenic plants were lower than those of wild type plants. Meanwhile, transgenic rice seedlings restored normal growth but wild type plants could not be rescued after drought and re-watering treatment. These findings indicate that over-expression of OsHsfA7 gene can increase tolerance to salt and drought stresses in rice seedlings.

• 성인간호학회지
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• 제25권2호
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• pp.113-124
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• 2013

Purpose: Purposes of this study were to develop a reliable and valid checklist to assess and manage post-stroke dysphagia and to identify its utilization. Methods: The first step was to develop checklist through systematic literatures reviews, to test the content validity from 11 clinical experts, and to test the construct validity and the internal consistency from 97 patients with post-stroke dysphagia. The second step was to identify clinical use of the checklist from the same 97 patients. Results: A total of 18 items compromised the assessment checklist and 64 items for intervention checklist. Internal consistencies of assessment checklist and intervention checklist were .84 and .98, respectively. In both checklists, level of utilization of general appearance was the highest, while that of early signs of aspiration was the lowest. The utilization levels of two checklists were significantly higher among patients who were less than 60 years old, and had liquid diet, facial paralysis, and previous history of aspiration pneumonia. Conclusion: We found that the checklists were reliable and valid. Further study is needed to develop specific strategies to improve nurses' use of assessment and intervention checklists for post-stroke dysphagia.

• 동아시아경상학회지
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• 제10권2호
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• pp.105-113
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• 2022

Purpose - An increase in automation has been as a result of digital technologies. The data will be instrumental in the determination of the services that are more necessary so that more resources can be allocated for them. The purpose of the current research is to investigate how big data utilization will help increase the profitability in the industry 4.0 era. Research design, Data, and methodology - The present research has conducted the comprehensive literature content analysis. Quantitative approaches allow respondents to decide, but qualitative methods allow them to offer more information. In the next step, respondents are given data collection equipment, and information is collected. Result - The According to qualitative literature analysis, there are five ways in which big data utilization will help increase the profitability in the industry 4.0 era. The five solutions are (1) Better Customer Insight, (2) Increased Market Intelligence, (3) Smarter Recommendations and Audience Targeting, (4) Data-driven innovation, (5) Improved Business Operations. Conclusion - Modern companies have been seeking a competitive advantage so that they can have the edge over other companies in the same industries providing the same services and products. Big data is that technology that businesses have always wanted for an extended period of time to revolutionize their operations, making their businesses more profitable.

• Applied Biological Chemistry
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• 제19권2호
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• pp.99-103
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• 1976

경남북지방(慶南北地方)에서 많이 재배(栽培)되고 있는 품종중(品種中) 8품종(品種)의 삽시(澁?)를 선정(選定)하여 탈삽(脫澁)에 따른 가용성(可溶性) tannin의 변화(變化), 경도(硬度) 및 당(糖)의 변화(變化)와 아울러 탈삽후(脫澁後)의 품질변화(品質變化)에 대(對)하여 조사(調査)한 결과(結果)는 다음과 같다. 1. 가용성(可溶性) tannin의 함량(含量)은 사곡시(舍谷?), 의성반시(義城盤?) 청도반시(淸道盤?)의 순(順)으로 많았으며 탈삽소요일수(脫澁所要日數)는 단성시(丹城?)가 2.5일(日)로 가장 빨랐으며 사곡시(舍谷?)가 가장 늦은 4.5일(日)이었다. 2. 경도(硬度)는 사곡시(舍谷?), 청도반시(淸道盤?)가 가장 높았고 채취 시기가 늦은 품종(品種)일수록 점차 저하(低下)되었다. 3. 당(糖)의 함량(含量)은 고종시(高宗?)가 가장 높았으며 사곡시(舍谷?)가 낮았다. 그리고 탈삽경과중(脫澁經過中) 당(糖)의 변화(變化)는 점차(漸次) 감소(減少)하였다. 4. 탈삽후(脫澁後) 품질유지(品質維持), 청도반시(淸道盤?), 사곡시(舍谷?), 의성반시(義城盤?)의 3품종(品種)이 양호(良好)하였다.

• Animal Bioscience
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• 제36권6호
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• pp.943-952
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• 2023

Objective: For decades, LYD ([Landrace×Yorkshire] ♀×Duroc ♂) pigs are the most commonly-used commercial breed for meat production in Korea. Recently, due to the increasing demand for premium pork, the National Institute of Animal Science (Korea) has synthesized a novel pig breed named Woori Heukdon (WHD). This study aimed at comparing the carcass traits, meat yield and quality characteristics between the LYD and WHD pigs under identical rearing condition. Methods: The WHD and LYD pigs (n = 15 each) were reared under identical conditions and fed the same commercial diet until reaching recommended market weight (100 to 120 kg). After slaughter, the carcasses were evaluated for traits and meat yield, and the meat quality was assessed on shoulder butt and belly cuts. Results: Although no significant differences (p>0.05) occurred in slaughter weight between two pig types, WHD had a lower meat yield (by about 6 kg corresponding to approximately 7%) compared to the LYD pigs (p<0.05). The WHD had a higher fat content (by 4.26% and 13.52% in the shoulder butt and belly, respectively) compared to those of LYD pigs (p<0.05). The WHD meat showed a lower cooking loss and higher a* (redness) value (p<0.05). The WHD belly had a significantly (p<0.05) higher oleic acid content and concentrations of nonanal, octanal and decanal associated with fatty odor while, the LYD meat had a higher number of pyrazines associated with roasty odor. Regarding sensory quality, higher flavor, juiciness, and acceptability higher scores were given for the WHD meat than for the LYD meat (p<0.05). Conclusion: Under identical rearing conditions the WHD exhibited a better meat quality and sensory properties. However, the use of this diet resulted in a high fat level that may be associated with high trimming loss for the WHD.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2002년도 봄 학술발표회 논문집
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• pp.903-908
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• 2002

The production of waste glasses has been increased with the development of industry. The utilization of waste glass for concrete can cause the concrete to be cracked and to be weakened due to an expansion by alkali-silica reaction(ASR). When used the fibers with waste glass, there is an effect on reduction of expansion and strength loss due to ASR between the alkali in the cement paste and the silica in the waste glass. In this study, we conducted basic experimental research to analyze the possibilities of recycling of amber waste glass as fine aggregates for steel fiber reinforced concrete. Test results of fresh concrete. slump is decreased because grain shape is angular and air content is increased due to involving small size particles so much in waste glasses. Also. tensile and flexural strengths increased as the content of steel fibers increased. In conclusion, the content of waste glass below 40% is reasonable and usage of pertinent admixture is necessary to obtain workability or air content.