• 한국지하수토양환경학회지:지하수토양환경
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• 제6권4호
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• pp.13-23
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• 2001

본 연구는 중금속 오염지반의 정화를 목적으로, Electrokinetic(EK) 기법을 적용 할 때 지반 내에서 pH와 오염물 분포특성을 알아보았다. 시료 내에서의 EK 처리로 인한 납 제거 효과를 살펴본 결과 1V/cm의 전압경사 하에서 납은 음극으로 이동하여, 전극 간 시료의 80%정도 영역에서 제거율은 대략 75% 정도에 이르렀다. 그러나 이동된 납은 대부분이 음극영역에 침전되어 궁극적으로 음극수로 배출되어 제거되는 납의 양은 미미하였다. 이때, EK 정화처리는 시료의 대부분인 80% 정도에서 토양환경보전법 상의 규준치를 만족할 수 있으나, 음극쪽 20%지역은 별도의 향상기법을 적용하여 처리하는 기법이 필요하다.

• 수산해양교육연구
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• 제15권1호
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• pp.81-100
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• 2003

It is undeniable that IUU Fishing are threatening so many legal fishermen' economic livelihood, negatively impact on conservation and protection of the fishery stock and ecosystem itself. Especially, negative impact of IUU Fishing resulted from the increasing fishery activities on the high seas. The Korea case of Coastal and Off-shore Fisheries, difficulties in conserving and controlling the fishery stock was brought about. Simultaneously, it is the fact that there are so many damage such as the reduction of fish Stock management program's effect, dissatisfaction of legal fishermen, over-exploiting of fish stock. Related with this kind of problem, FAO had adopted "International Plan of Action to Prevent, Deter and Eliminate Illegal, Unreported and Unregulated Fishing(2001)". From this reason, Korea also needs to make actual efforts to prevent IUU Fishing. i.e. each nation should develop Korea action plan by Feb. 2004 and impliment it, report on implementation toward FAO. This Paper will review the definition of the IUU stipulated by "International Plan of Action on Illegal, Unreported and Unregulated Fishing" and study Korea cases of the IUU fishing. Finally, the analysis of Korea's implementation will be done, centering around the contents stated on the International Action Plan. The significance of this paper is to grope the political countermeasures against international movement of the IUU fishing prevention.

• 한국자동차공학회논문집
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• 제18권3호
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• pp.53-59
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• 2010

The Developing & Producing of Eco-Friendly vehicle have been more incremented, as People appreciate the importance of Earth Environment Conservation. The needs of Neighborhood Electric Vehicle(NEV) that suits Current people's short drive distance is incremented. In this Paper, we define Neighborhood Electric Vehicle through out National Highway Traffic Safety Administration of United States of America's regulation and explain motor and battery of primary constituents of that. We used MATLAB and ADVISOR 200 programs for Simulation, and propsed NEV's Model that tow people can be got in. In this Model, the battery is Lead-acid battery(72V, 85Ah) and the motor is 8kW permanent magnet synchronous motor(PM motor). We compared change of driving range of NEV through out non-changing speed Driving(10km/h, 20km/h, 30km/h, 40km/h) and Manhattan driving schedule.

• Molecules and Cells
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• 제41권1호
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• pp.35-44
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• 2018

Mitochondria are responsible for supplying of most of the cell's energy via oxidative phosphorylation. However, mitochondria also can be deleterious for a cell because they are the primary source of reactive oxygen species, which are generated as a byproduct of respiration. Accumulation of mitochondrial and cellular oxidative damage leads to diverse pathologies. Thus, it is important to maintain a population of healthy and functional mitochondria for normal cellular metabolism. Eukaryotes have developed defense mechanisms to cope with aberrant mitochondria. Mitochondria autophagy (known as mitophagy) is thought to be one such process that selectively sequesters dysfunctional or excess mitochondria within double-membrane autophagosomes and carries them into lysosomes/vacuoles for degradation. The power of genetics and conservation of fundamental cellular processes among eukaryotes make yeast an excellent model for understanding the general mechanisms, regulation, and function of mitophagy. In budding yeast, a mitochondrial surface protein, Atg32, serves as a mitochondrial receptor for selective autophagy that interacts with Atg11, an adaptor protein for selective types of autophagy, and Atg8, a ubiquitin-like protein localized to the isolation membrane. Atg32 is regulated transcriptionally and post-translationally to control mitophagy. Moreover, because Atg32 is a mitophagy-specific protein, analysis of its deficient mutant enables investigation of the physiological roles of mitophagy. Here, we review recent progress in the understanding of the molecular mechanisms and functional importance of mitophagy in yeast at multiple levels.

• 한국물환경학회지
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• 제21권4호
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• pp.305-313
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• 2005

In these days, water environment is getting threatened by a variety of toxic pollutants discharged from industries. However, environmental standards and regulations in Korea may be in straitened circumstances to protect the water environment from it. Therefore, the purpose of this review is to compare the management state of the toxic substances in water environment and to present the framework for deriving water quality criteria in USA and Japan. To conserve the water environment from the toxic pollutants more efficiently, the following considerations could be suggested in standards and regulation in Korea. Firstly, there should be consistency of regulated pollutants in drinking water quality standard, water quality standards and permissible wastewater discharge standards. Secondly, in case of deriving the water quality standards, it is required to consider the conservation of the aquatic ecosystem as well as the protection of human health. Finally, it is indispensable to make risk-based approach in management of toxic pollutants in water environment.

• Genomics & Informatics
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• 제6권2호
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• pp.72-76
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• 2008

Hypoxia-inducible factor $1{\alpha}\;(HIF1{\alpha})$ is a transcription factor that plays a key role in the adaptation of cells to low oxygen stress and oxygen homeostasis. The oxygen-dependent degradation (ODD) domain of $HIF1{\alpha}$ is responsible for the negative regulation of $HIF1{\alpha}$ in normoxia. The interactions of the $HIF1{\alpha}$ ODD domain with partner proteins such as von Hippel-Lindau tumor suppressor (pVHL) and p53 are mediated by two sequence motifs, the N- and C-terminal ODD(NODD and CODD). Multiple sequence alignment with $HIF1{\alpha}$ homologs from human, monkey, pig, rat, mouse, chicken, frog, and zebrafish has demonstrated that the NODD and CODD motifs have noticeably high conservation of the primary sequence across different species and isoforms. In this study, we carried out molecular dynamics simulation of the structure of the $HIF1{\alpha}$ CODD motif in complex with the p53 DNA-binding domain (DBD). The structure reveals specific functional roles of highly conserved residues in the CODD sequence motif of $HIF1{\alpha}$ for the recognition of p53.

• Environmental Engineering Research
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• 제18권2호
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• pp.65-69
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• 2013

Despite the most severe weather and geological conditions, Korean people in earlier times were successful in maintaining sustainable water supplies because they understood the importance of rainwater management, and developed technologies and a philosophy which were needed to live under such circumstances. Recently, the Korean people have suffered frequent incidence of flood damage and drought, and have gradually started to remind themselves of the lessons of the past, which can be described as proactive, multipurpose rainwater management. Most of the problems associated with water and energy can be solved by the integration of rainwater management practices. The concept of multipurpose rainwater management and two examples of its practice are discussed. One is a design for a multipurpose rainwater tank which has been used in a building project, and is based on Korean philosophy. Secondly, a regulation was promulgated recently in Seoul that requires the building of rainwater tanks in new buildings over a certain size. The primary purpose is for the prevention of flooding, but water conservation is a secondary intention. Two examples of proactive rainwater management are discussed, one being public involvement in rainwater management, and the second being the rainwater piggy bank microcredit project. In order to maintain sustainability, to meet the requirements of the Millennium Development Goals, and to be prepared for the effects of climate change, it is expected that multipurpose and proactive rainwater management will be a very effective approach for both developing countries and developed countries. A worldwide network of scientific researchers, as well as a great number of professions, has suggested the promotion of rainwater management.

• Molecules and Cells
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• 제26권3호
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• pp.228-235
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• 2008

Thiol-dependent redox systems are involved in regulation of diverse biological processes, such as response to stress, signal transduction, and protein folding. The thiol-based redox control is provided by mechanistically similar, but structurally distinct families of enzymes known as thiol oxidoreductases. Many such enzymes have been characterized, but identities and functions of the entire sets of thiol oxidoreductases in organisms are not known. Extreme sequence and structural divergence makes identification of these proteins difficult. Thiol oxidoreductases contain a redox-active cysteine residue, or its functional analog selenocysteine, in their active sites. Here, we describe computational methods for in silico prediction of thiol oxidoreductases in nucleotide and protein sequence databases and identification of their redox-active cysteines. We discuss different functional categories of cysteine residues, describe methods for discrimination between catalytic and noncatalytic and between redox and non-redox cysteine residues and highlight unique properties of the redox-active cysteines based on evolutionary conservation, secondary and three-dimensional structures, and sporadic replacement of cysteines with catalytically superior selenocysteine residues.

• 한국태양에너지학회 논문집
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• 제31권1호
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• pp.23-30
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• 2011

International cooperation to reduce greenhouse gas emissions is expected to provide a big crisis and a great opportunity at the same time for our industry that heavily consumes energy. To cope actively with the international environmental regulation, such as the Framework Convention on Climate Change, quantitative measurement of the volume of greenhouse gases emitted by various industries and quantitative prediction of the greenhouse gas emissions of the future are becoming more important than anything else at the national level. This study aims to propose the calculation process of carbon dioxide($CO_2$) emission for building in life cycle. This paper describes and compares 9 different tool for environmental load estimation with LCA. This study proposed the calculation process for quantitatively predicting and assessing $CO_2$ emissions during the life cycle of buildings based on the life cycle assessment(LCA). The life cycle steps of buildings were divided into the design/supervision, new construction, repair, renovation, use of operating energy in buildings, maintenance, and reconstruction stage in the life cycle inventory analysis and the method of assessing the environmental load in each stage was proposed.

• Animal cells and systems
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• 제3권1호
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• pp.1-7
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• 1999

Gonadotropin-releasing hormone (GnRH) was originally isolated as a hypothalamic peptide that regulates reproduction by stimulating the release of gonadotropins. Using comparative animal models has led to the discovery that GnRH has a more ancient evolutionary origin. Durinq evolution GnRH peptide underwent gene duplication and structural changes to give rise to multiple molecular forms of GnRHs. Mammalian GnRH initially considered to be the sole molecular form, is now grouped as a family of peptides along with GnRH variants determined from representatives in all classes of vertebrates. Vertebrate species including primates and humanshave more than one GnRH variant in individual brains; a unique GnRH form in the forebrain and chicken IIGnRH in the midbrain. Furthermore, several species of bony fish have three molecular variants of GnRH: salmon GnRH sea-bream GnRH and chicken II GnRH. Also, it has been shown that in addition to the olfactory placodes and the midbrain, there is a third embryonic source of GnRH neurons from the basal diencephalon in birds and fish, which might be true for other vertebrates. Therefore, comparative animal models like fish with discrete sites of expression of three molecular variants of GnRH in individual brains, could provide insight into novel functions of GnRH variants, conservation of gene regulation, and mechanisms governing reproduction in vertebrates.