• Journal of Naturopathy
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• v.11 no.2
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• pp.136-142
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• 2022

Background: We are necessarily considering changes in the parasite infection rate and methods in Korea from 1970 to the present from the perspective of natural healing. Purposes: This study was to investigate how the difference in the rate of reduction in infection rate has changed and progressed to the present. Methods: A literature review was conducted. Results: Until the 1970s, Korea had one of the highest parasite infection rates. The Parasitic Disease Prevention Act was enacted to control the infection rate in 1966. From 1969, the nationwide national parasite management project was conducted for all students twice a year to treat all parasitic eggs until 1995. In addition, the government commissioned the Korean Association for Parasite Eradication (KAPE) to conduct a national parasite infection survey eight times, from 1971 to 2012, every two years. As a result, the overall egg positive rate of parasite was 84.3% in 1971 but decreased to 2.6% in 2012. In addition, Ascaris lumbricoides, Paragonimus westermani, Taenia spp., and intestinal protozoa were significantly reduced nationwide. Conclusions: Successful control in Korea is judged to have achieved a successful effect by systematically managing national economic growth, social consensus on parasite eradication, improved professional parasite prevention guidelines, and supply of effective anthelminthics.

• Journal of the Korean Society for Marine Environment & Energy
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• v.12 no.4
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• pp.284-288
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• 2009

The International Convention for the Control and Management of Ships Ballast Water & Sediments was adopted by consensus at a diplomatic conference of IMO at 2004. To prepare the Ballast Water Management Convention, fundamental technologies such as treatment system, type approval, risk assessment and various technical informations for formulation of the regulation for national strategy shall be developed. The information item of voyage and discharge of ship's ballast water are gathered by visiting vessel and agent at port. Using the 97 results by ships type characteristic analysis on the relation between loading/unloading and discharge/uptake of ballast water, the amounts of discharge/uptake of ballast water at each port and all of country in Korea are predicted. Hence, It is apparent that the uptake of ballast water is predicted to about 70 million ton in total of Busan, Incheon, Kwangyang and Ulsan ports at 2006 which is over 3 times than discharges.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.4
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• pp.2355-2359
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• 2013

Vulva cancer is rare among all gynecological cancer worldwide, including Thailand, and mainly affects older women. Persistent high risk type infection of human papillomavirus (HPV) is the one important factor for developing cancer. In this study, we focused on HPV DNA investigation and type-specific distribution of HPV in 25 formalin-fixed paraffin-embedded (FFPE) samples collected from Thai women with vulva cancer histologically confirmed by the National Cancer Institute, Thailand, during 2003-2011. HPV DNA detection and genotyping were undertaken with polymerase-chain reaction and enzyme-immunoassay using GP5+/bio6+ consensus specific primers and digoxigenin-labeled specific oligoprobes, respectively. Human ${\beta}$-globin genes was used as the internal control. Our results showed that 44% (11/25) of all vulva cancer samples were HPV-positive. All of them are high risk HPV type infection, detected as single (63.64%, 7/11) and/or double infections (4/11, 36.36%). HPV 16 was the most common type identified in vulva cancer, followed by HPV 35, 33, 18 and 58. In conclusion, this study presented that HPV-16 is observed at the highest frequency in this cancer, similar to cervical cancer, with HPV 18 being less frequent. Although the sample size was small and could not represent overall incidence and prevalence in Thai women, these preliminary data for vulva cancer are of interest since they reinforce the necessity for HPV screening or vaccination in Thailand.

• Environmental Mutagens and Carcinogens
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• v.21 no.2
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• pp.89-94
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• 2001

Recently, single cell gel electrophoresis, also known as comet assay, is widely used for the detection and measurement of DNA strand breaks in vitro and in vivo in many toxicological fields such as radiation exposure, human monitoring and toxicity evaluation. As well defined, comet assay is a sensitive, rapid and visual method for the detection of DNA strand breaks in individual cells. Briefly, a small number of damaged cells suspended in a thin agarose gel on a microscope slide were lysed, unwinded, electrophoresed, and stained with a fluorescent DNA binding dye. The electric current pulled the charged DNA from the nucleus such that relaxed and broken DNA fragments migrated further. The resulting images which were subsequently named for their appearance as comets, were measured to determine the extent of DNA damages. However, some variations could be occurred in procedures, laboratories's conditions and kind of cells used. Hence, to overcome and to harmonize these matters in comet assay, International Workshop on Genotoxicity Test Procedure (IWGTP) was held with several topics including comet assay at Washington D.C. on March, 1999. In spite of some consensus in procedures and conditions in IWGTP, there are some problems still remained to be solved. In this respect, we attempted to set the practical optimal conditions in the experimental procedures such as lysis, unwinding, electrophoresis and neutralization conditions and so on. First of all, we determined optimal lysis and unwinding time by using 150 $\mu$M methyl methanesulfonate (MMS) which is usually used concentration. And then, we determined optimal positive control concentrations of benzo(a)pyrene (BaP) and MMS in the presence and absence of S9 metabolic activation system, respectively.

• Journal of Microbiology and Biotechnology
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• v.11 no.1
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• pp.131-137
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• 2001

Previous work has identified that only the catabolite responsive element A (creA; previously called cre-2) out of two potential cre sequences (cre-1: nucleotide +160 to +173 and cre-2: +173 to +186), recognized within the coding region of the xylanaseA gene (xynA) of Bacillus stearothermophilus No.236, was actually, was actually involved in the carbon catabolite repression(CCR) of xynA expression in B. subtilis. However, the level of CCR of xynA expression in the original B.stearothermophilus No.236 strain (70-fold repression). Therefore, to search for an additional cre element in the promoter region, the upstream region of the xynA gene was subcloned by chromosome walking, and as a result, another potential cre element (nucleotide -124∼-137; designated creB) was recognized in this region. The cre-like sequence revealed a high homology to the cre consensus sequence. The xylanase activity of B. subtilis MW15 bearing pWPBR14 (containing creA and creB) cultured in a medium containing xylose as the sole carbon source was about 7.7 times higher than that observed for the same culture containing glucose. B. subtilis MW15 bearing pWPBR23 (containing only creA) produced an activity about 2.4 times higher. This pattern of CCR was confirmed using derivatives of xynA::aprA fusion plasmids. Furthermore, a measurement of the amounts of the xynA transcript showed a similar pattern as that for the production of xylanase. In addition, the synthesis of xylanase in B. subtilis QB7115 [a catabolite control protein A (ccpA) mutant strain] carrying pWPBR14 was almost completely relieved from glucose repression. Together, these results lead to a conclusion that the CCR of the expression of the xynA gene is mediated by CcpA binding at creA and creB sites in B. subtilis.

• Health Policy and Management
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• v.1 no.1
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• pp.3-18
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• 1991

On the stage of transition from highly centralized government to local self-government in Korea, administrating practice characteristics of the directors of Health Centers is essentially required to be found. This study was conducted in order to find the administration patte군 of the directors of Health Centers in Korea and their opinion on the environment of health administration including personnel management regime for them. The materials were collected from 149 directors of Health Centers with a structured questionaire by mailing. The major findings of this study were as follows. 1. About two-thirds of the directors(69.1%) make plan through the consensus between public service perosonnel in programme department and them in budgt control department. And 75.0% of the directors maintain the planed by the predecessor. 2. More than two-thirds of the directors (71.1%) take subordinates opinion into consideration in case of the programmes facing objections. 3. When the directors face obstacles in pursuing health programmes they usually consult other public service personnel than inhabitants. 4. Only 10.8% of the directors were satisfied with the support of the Ministry of Internal Affairs for health administration while more than half of them were satisfied with the support of health institution in higher level. 5. The directors evaluated the job attitude of the public service personnel in low level as more favorable than that of there higher level public service personnel who work for central government. 6. Only 18.1% of the idrectors were satisfied with their saley. And more than half of them expect the promotion of their position. On the ground of this result the administration attitude of the directors of Health Centers would be evaluated as improved and as more positive than that of other public service personnel in health authorities. However, they are required to consult the inhabitants more frequently for health administration. An the public service personnel in high level who work for central government are required to improve their job attitude.

• Journal of The Korean Digital Architecture Interior Association
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• v.10 no.2
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• pp.21-30
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• 2010

Students in the field of architectural design, form and design of the new learning process, and in the design of a very premiere. Perhaps one way of theoretical training and strict discipline academy will probably already be familiar with. In addition to academic activities rather passive liberal arts students, learning basic academic skills than students, vocational students lag is most. However, these have been popular with young sensibility popular consensus here and he has the potential to move actively. This is very sporadic but does not control the many, it's even the potential fragmentation of consciousness, because they themselves do not know a lot of parts. Therefore, the power embodied in the design process and disclose the outside, it fits in the design field to produce results. And designed to improve learning ability and motivation to want to promote. Accordingly, this research through the following four methods to test the methodology on the basis of the results and try to find solutions to problems. (1) Outside the student's latent ability to express emotion should be. (2) Students' interests are actively utilized in the design classes. (3) Analysis of individual interests and ideas, and how to take advantage of the design process that is induced. (4) The final work should express your own personality into the design. Through this, students' academic motivation and a positive vision of the direction of design is proposed.

• Genomics & Informatics
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• v.5 no.4
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• pp.174-178
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• 2007

The earliest stages of mammalian embryogenesis are governed by the activity of maternally inherited transcripts and proteins. Cytoplasmic polyadenylation of selected maternal mRNA has been reported to be a major control mechanism of delayed translation during preimplantation embryogenesis in mice. The presence of cis-elements required for cytoplasmic polyadenylation (e.g., CPE) can serve as a useful tag in the screening of maternal genes partaking in key functions in the transcriptionally dormant egg and early embryo. However, due to its relative simplicity, UA-rich sequences satisfying the canonical rule of known CPE consensus sequences are often found in the 3'-UTR of maternal transcripts that do not actually undergo cytoplasmic polyadenylation. In this study, we developed a method to confirm the validity of candidate CPE sequences in a given gene by a multiplex comparison of 3'-UTR sequences between mammalian homologs. We found that genes undergoing cytoplasmic polyadenylation tend to create a conserved block around the CPE, while CPE-like sequences in the 3'-UTR of genes lacking cytoplasmic polyadenylation do not exhibit such conservation between species. Through this cross-species comparison, we also identified an alternative CPE in the 3'-UTR of tissue-type plasminogen activator (tPA), which is more likely to serve as a functional element. We suggest that verification of CPEs based on sequence conservation can provide a convenient tool for mass screening of factors governing the earliest processes of mammalian embryogenesis.

• Journal of the Korean Society of Physical Medicine
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• v.12 no.4
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• pp.139-146
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• 2017

PURPOSE: The purpose of this study was to systematically analyze the reliability and validity of the Korean-version of the balance assessment tools. METHODS: Two reviewers of this study independently evaluated the titles of articles and abstracts of studies published until December 2016 through electronic databases (RISS, NDSL, KISS, DBpia) using the keywords "Balance or posture or postural control or postural stability", "Test or assessment or measurement or outcome measure or assessment tool or measurement tool", "Korean version", "Reliability" and "Validity". Regarding the questions considered suitable for the purpose of this study, consensus was reached after reading the full text. Selecting journals suitable for the purpose of the study, they were analyzed as data. RESULTS: The reviewers selected nine papers suitable for the purpose of this study, and Korean-version of the balance assessment tools, included the Berg Balance Scale (BBS), Activities-specific Balance Confidence (ABC) scale, Postural Assessment Scale for Stroke (PASS), Motor Assessment Scale (MAS), Trunk Impairment Scale (TIS), Falls Efficacy Scale (FES), Tinetti-Balance scale, Fullerton Advanced Balance (FAB) scale, and Function In Sitting Test (FIST). Our study showed that the reliability and validity of the Korean-version of the balance assessment tools were high. CONCLUSION: The Korean-version of the balance assessment tools with high reliability and validity would enable physical therapists to make a more accurate evaluation of balance.

• Journal of the Korean association of regional geographers
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• v.14 no.3
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• pp.224-238
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• 2008

Traditional industrial complex in inner city has been getting stagnant and deteriorating because of the improvement of industrial structure and change of the city's spatial restructuralization. Third Industrial Complex is also characterized by the deterioration in the field such as the reduction of average number of the workers and the amount of production, the change of main types of business, subdivision of many parts, and the change of the price of land. Thus, local government is planning to change the complex into a high-tech industrial complex in the inner city. On the other hand, the companies which are undergoing the direct deterioration do not fully recognize the government plan to redevelop the complex, and there is no counter measure against the stagnation and deterioration. Therefore, the local government must have much time to discuss and have a consensus with the companies in the complex, and organize the control office which is able to mediate between the local government and the companies.