• Development and Reproduction
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• v.2 no.2
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• pp.165-171
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• 1998

p62 is a novel cytoplsmic protein that binds to SH2 domain of p56$^{lck}$, lymphocyte-specific protein tyrosine kinase, and the expression of p62 was observed in most tissues. In addition p62 interacts with various proteins including ubiquitin and atypical PKC isoform, indicating its diverse biological role in different tissues. However, little is known about functional connection between p62 and its binding proteins. In the present study, a novel cellular protein, p62 has been shown to bind to 14-3-3 $\tau$ isoform that is specific for T cells. Moreover, overexpression of p62 in T cells caused to delay onset of UV-induced apoptosis characterized by DNA fragmentation and breakdown of poly (ADP-ribose) polymerase (PARP). Lately, 14-3-3 proteins have been shown to mediate survival signal via interacting proapoptotic Bad protein in the Iymphocyte. These results suggested the presence of p62-mediated regulatory mechanism during apoptosis in T cells, in which activation-induced apoptotic signal could be interfered by p62 and 14-3-3 protein.n.

• Journal of Information Technology Applications and Management
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• v.15 no.4
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• pp.159-188
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• 2008

This study suggests strategies which can enable to creation of new opportunities of competitive advantages while operating a long lasting and consistent business with major trading partners, based on interorganizational information systems (IOISs) specially established and installed for interorganizational transactions. Nowadays, IOISs based mechanism having been widely expanded as a conventional business infrastructure for the interorganizational transactions and/or exchanges, it is customary difficult to obtain any strongly sound advantage over the competitors who have adopted even the simplest deployment of the IOIS mechanisms. In this connection, this study intends to investigate the interorganizational collaborative activities conducted by under the auspicious of IOISs, focused on the prospect of the exploitation of IOISs rather than the implementation of the IOISs. In this study, we, firstly, suggest the concept of Electronic Collaboration which can be defined by the collaborative activities conducted by IOISs, compared to the ones conducted on off-line. In addition, we suggest the Electronic Collaboration as a multi-dimensional concept, constituted by three sub-constructs, the Electronic Information Sharing (EIS), the Electronic Joint Activity (EJA), and the construction of the Electronic Relational Knowledge Store (ERKS). Secondly, we empirically verify the effects of relational and environmental determinants on the Electronic Collaboration. In this study, the relational determinants relate to the variables created in interorganizational relationship like Trust, Influence, Relational Specific Asset-asset invested for the transaction-, and Continuity of the relationship. On the other hand, the environmental determinants relate to the variables surrounding the relationship which are difficult to control. We consider Product Complexity, Technological Uncertainty, and Market Variability as the domain of the environmental determinants. To test our hypotheses, we conducted both paper-based survey and online-based survey. After refining the data with missing responses, a total of 150 data was used for analysis. The results were as follows : Firstly, it is statistically significant that the Electronic Collaboration is composed of EIS, EJA, and ERKS. In particular, the results imply that the firms are able to accumulate relational knowledge base as well as to exchange information or knowledge, and to conduct joint activities through effort to further expand the Electronic Collaboration. Secondly, we have verified the individual effects of the relational and the environmental determinants on the Electronic Collaboration. Product Complexity has been revealed as the most influential variable affecting the Electronic Collaboration. Next, Interorganizational Trust and Technological Uncertainty, in that order, have been seen to have significant effects on the Electronic Collaboration. In other words, when products or services seem to be difficult to standardize, and the core technologies seem to rapidly change, the need for the Electronic Collaboration increase. In addition, the observation dictates that the interorganizational trust turns out to be a critical variable in building a relationship and in seeking further collaboration. The results, further, illustrate that the environmental determinants are relatively more effective than the relational determinants, which is not consistent with a few prior researches relational determinants emphasized. It is because this study doesn't consider the size of the firm. A few researchers have given an emphasis on the relational determinants like trust and influence, especially from the perspective of small firms in interorganizational relationship. However, in our study, where all the sizes of the firms are contained, electronic collaboration is considerably affected by the environmental determinants.

• Journal of Korea Multimedia Society
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• v.7 no.9
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• pp.1208-1218
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• 2004

Nowadays the information exchange based on XML such as B2B electronic commerce is spreading. Therefore a systematic and stable management mechanism for storing the exchanged information is needed. For this goal there are many research activities for centering on relational databases the connection between XML application and databases. But when XML data which has hierarchical structure is stored as relational databases which are expressed as relational information, a set of 2-dimensional table, there is a limitation essentially. Accordingly the modeling methodology for storing such structured information in the form of object-relational databases is needed. In order to build good quality application systems, modeling is an important first step. In 1997, the OMG adopted the UML as its standard modeling language. Since industry has warmly embraced UML, its popularity should become more important in the future. So a design methodology based on UML is needed to develop efficient XML applications. In this paper, we propose a unified design methodology for XML applications based on object-relational database using UML. To reach these goals, first we propose a systematic three step methodology to extract UML, second we introduce a XML modeling methodology to design W3C XML schema using UML and third we propose a data modeling methodology for object-relational database schema to store exchanging XML data efficiently.

• Magazine of the Korean Society of Agricultural Engineers
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• v.10 no.1
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• pp.1377-1387
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• 1968

In order to measure runoff and soil losses produced in a small test plot during rainfall, it is usually insufficient to use a tank only, necessitating the combined use of a main tank and a subsidiary tank. Accordingly. exact measurement largely depends on how to connect those two measuring tanks. The main purpose of this thesis is to improve the connecting parts of two measuring tanks so as to assure exact measurement of runoff and soil losses. In this experiment, two types of main tank, i. e. A-type and B-type, were used. A-type is a square tank having a flume at its end. At the flume, ten apertures are provided by using metal columns so as to be able to catch one tenth of total muddy flow discharging at the end of the flume, One tenth of total flow is led to the subsidiary tank through a slot sampler fixed to an aperture. B-type differes in that its flume does not have apertures and slot sampler is fixed directly to the end of the flume, other features being the same as those of A-type. Discharge volumes were measured by using weighing tanks and compared. The effect of baffle screen provided in the flume was also observed in connection with exact measurements. In order to keep main tank and its flume in a horizontal position, bolts and nuts mechanism was used. Vertical and horizontal screens were provided in the main to prevent coarse sands coming into the flume. The conclusion derived through this experiment is as follows: (1) The discharge through slot sampler at each aperture is almost the same for A-type. However, it is slightly more than one tenth of total discharge volume. (2) In case that baffle screen is provided in the flume of A-type tank, the discharge volume of slot sampler is less than that of the same type without screen. (3) For B-type tank, slot sampler discharge increases as slot sampler nears toward the center of flume. (4) When baffle screen is provided in the flume of B-type, slot sampler discharge is less than that of the same type without screen, and this phenomenon is more apparent as compared with A-type. (5) In case that the slot width of slot sampler for B-type is one inch, slot sampler discharge exceeds one tenth of total discharge volume. (6) When the slot width for B-type is 15/16 inch and slot sampler is fixed 3/8 inch apart from either flume wall, slot sampler discharge is approximately equal to one tenth of total discharge volume.

• Journal of Microbiology and Biotechnology
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• v.27 no.6
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• pp.1078-1089
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• 2017

Biofilm formation of Staphylococcus aureus is one of its mechanisms of drug resistance. Anti-biofilm screening of 106 compounds from marine-derived fungi displayed that 12 compounds inhibited S. aureus biofilm formation by >50% at the concentration of $100{\mu}g/ml$, and only secalonic acid D (SAD) and B inhibited by >90% at $6.25{\mu}g/ml$ without inhibiting cell growth after 24-h incubation. Meanwhile, it was found that the double bond between C-1 and C-10 of citrinin derivatives and the C-C connection position of two chromone monomers may be important for their anti-biofilm activities. Moreover, SAD slightly facilitated biofilm eradication and influenced its architecture. Furthermore, SAD slowed the cell growth rate in the preceding 18-h incubation and differentially regulated transcriptional expression of several genes, such as agr, isaA, icaA, and icaD, associated with biofilm formation in planktonic and biofilm cells, which may be the reason for the anti-biofilm activity of SAD. Finally, SAD acted synergistically against S. aureus growth and biofilm formation with other antibiotics. These findings indicated that various natural products from marine-derived fungi, such as SAD, could be used as a potential biofilm inhibitor against S. aureus.

• The Journal of the Korea Contents Association
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• v.4 no.4
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• pp.123-131
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• 2004

Internet is absolutely contributed to information technology revolution nowadays. Internet services such as voice and data, etc. are provided home or small office via home gateway. The development of communication equipment via home gateway is implemented rapidly, and its product various. This paper presents the design and implementation of the VoIP equipment including the telephone function based on the embedded environment and being connected to the home gateway and the PC because of taking 2-ethernet LAN ports. As developing environment, the STLC1502 developed at ST Microelectronics as single chip solution, VxWorks as RTOS, and C language as coding mechanism are used. The verification of the developed systems for the voice test is carried out for the gatekeeper via Internet. The performance parameter is considered as the call processing capacity measuring the time of the call setup and clearing, and the data processing capacity for the file transfer. As a call setup and clearing is about 95ms, the call processing capacity is about 10 calls per second. The data processing capacity is 5.7Mbps in case of file transfer of server and client environment. Therefore the performance result is satisfied in the aspect of the call processing time and the data transfer time in Internet.

• Journal of KIISE:Information Networking
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• v.31 no.5
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• pp.501-510
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• 2004

While the Internet keeps its permeation into every aspect of human life, two things stand out. One is the requirement for high quality of services to support multimedia data service.'The other is the desire for ubiquitous network connection. Combining the two things makes the Internet possible in supporting multimedia communications for nomadic users on the locomotion. To support QoS communication for mobile users by applying RSVP to Mobile IP, RSVP Tunnel, which specifies building separately a RSVP session between the home agent and the foreign agent, was proposed. However, the RSVP Tunnel method breeds bandwidth overhead and association problems in tunnel because of duplicated RSVP messages use. To resolve these problems, in this paper, we propose the new encapsulation method, the RSVP-in-IP Encapsulation (RIPE) that can support QoS guaranteed service efficicntly in Mobile IP networks. The proposed method supports RSVP mobility to Mobile If tunneling mechanism efficiently without any additional session as the RSVP Tunnel scheme. Moreover it removes the critical problems of bandwidth overhead in a tunnel and association by duplicated messages. We compared the performance of our proposed scheme with RSVP Tunnel scheme in term of mean delay, mean data rate and bandwidth overhead in tunnel.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.24 no.9A
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• pp.1285-1294
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• 1999

In this paper we consider the performance of TCP video traffic over ABR with Long-Range Dependent VBR traffic. As compressed coded video traffics are increasing rapidly over Internet, lots of studies are being done for transmitting those traffics efficiently using limited network resources. We consider here the transmitting video service over ABR service in ATM networks, especially satellite networks. CBR or VBR services are suggested in transmitting the video traffic in ATM Forum TM 4.0. But ABR service connection, which is considered as appropriate service for data traffic, can be established with a small amount of bandwidth, MCR (Minimum cell rate). Furthermore ABR service can control the source's transmitting rate using feedback mechanism. Using this feature ABR service can be used in some applications which can control their quality of services corresponding to network loads. Compressed video sources with MPEG-2 are used for Long-Range Dependent VBR traffic here. We model the compressed video source to resemble the MPEG-2 transport streams. These compressed video traffic streams are consisted of three different frames, I-frame, P-frame, and B-frame. So when a network are overloaded, we can control the quality of service using this traffic features. TCP Traffics over ABR need large buffers in ATM switch to satisfy their QoS with background VBR traffics, which have high deviations in bandwidth. Furthermore satellite ATM networks with large feedback delay need large buffers corresponding RTT delay. The performance comparisons among EFCI and ER switch (ERICA+) switches in the network circumstances described above were shown in this paper. We also considered the case with ON-OFF VBR traffics.

• The KIPS Transactions:PartC
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• v.15C no.3
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• pp.157-166
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• 2008

The ubiquitous service environment is poor in reliability of connection and also has a high probability that the intrusion against a system and the failure of the services may happen. Therefore, It is very important to guarantee that the legitimate users make use of trustable services from the viewpoint of security without discontinuance or obstacle of the services. In this paper, we point out the problems in the standard Jini service environment and analyze the Jgroup/ARM framework that has been developed in order to help fault tolerance of Jini services. In addition, we propose a secure Jini service architecture to satisfy the security, availability and quality of services on the basis of the analysis. The secure Jini service architecture we propose in this paper is able to protect a Jini system not only from faults such as network partition or server crash, but also from attacks exploiting flaws. It provides security mechanism for dynamic trust establishment among the service entities. Moreover, our secure Jini service architecture does not incur high computation costs to merge the user service states because of allocation of the replica based on each session of a user. Through the experiment on a test-bed, we have confirmed that proposed secure Jini service architecture is able to guarantee the persistence of the user service states at the level that the degradation of services quality is ignorable.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.18 no.5
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• pp.708-720
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• 1993

The new preventive control mechanisms for traffic management in BISDN/ATM networks can be divided into Connection Admission Control(CAC), Usage Parameter Control (UPC), and Priority Control. Of these mechanism, Usage Parameter Control continuously monitors the parameters admitted in the network's entry point to guarantee quality of service of connections already admitted. Upon detecting traffic that violates the negotiated parameter, it takes the necessary control measures to prevent congestion. Among these traffic control methods, this paper focuses on the Usage Parameter Control method, and proposes and designs GRACE-LB(Guaranteed Rate Acceptance & Control Element-using Leaky Bucket) which improves upon existing UPC models. GRACE-LB modifies the previous LB model by eliminating the cell buffer, dividing the token Pool into two pools, Long-term pool, Short-term pool, and changing the long-term token generating form using 'Cycle Token' into the same bursty form as the traffic source. Through this, GRACE-LB achieves effective control of the Average Bit Rate(ABR) and burst duration of bursty multimedia traffic which previous LB models found difficult to control. Also, since GRACE-LB can e implemented using only simple operations and there are no cell buffers in it, it has the merit of being easily installed at any place.