• Journal of Chest Surgery
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• v.29 no.9
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• pp.1031-1035
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• 1996

International Ass ciation for the Study of Lung Cancer(IASLC) recommended the following classification of small cell lung carcinoma(SCLC) : (1) Small cell carcinoma (2) Mixed small cell/large cell carcinoma (3) Combined small cell carcinoma. Combined small cell carcinomas contain a squamous cell carcinoma or adenocarcinoma component. The prognostic significance of these elements is not known, but since the frequency and extent of non-small cell elements are considerably greater in posttherapy and autopsy tissues, it is possible that the non-SCLC elements are more resistant to therapy than the SCLC cells. Metaplasia & dysplasia of the bronchial surface epithelium are frequently observed in the bronchial biopsy specimens that contain small cell carcinoma of the lung. We report a case of combined small cell carcinoma with squamous element associated with microinvasive squamous cell carcinoma of the bronchial surface epithelium in 68 year old male patient, stage was IIIa. The two lesion are not connected n serial sections.

• Journal of the Institute of Convergence Signal Processing
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• v.7 no.3
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• pp.95-101
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• 2006

A face detection plays an important role in face recognition, video surveillance, and human computer interaction. In this paper, we propose a progressive threshold method to detect human faces in real time. The consecutive face images are acquired from camera and transformed into YCbCr color space images. The skin color of the input images are separated using a skin color filter in the YCbCr color space and some candidated face areas are decided by connected component analysis. The intensity equalization is performed to avoid the effect of many circumstances and an arbitrary threshold value is applied to get binary images. The eye area can be detected because the area is clearly distinguished from others in the binary image progressive threshold method searches for an optimal eye area by progressively increasing threshold from low values. After progressive thresholding, the eye area is normalized and verified by back propagation algorithm to finalize the face detection.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.29 no.4
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• pp.359-365
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• 2011

This study aims at filtering ALS points into ground and non-ground effectively through labeling and window based algorithm by utilizing 2D adjacency based on scan line. Firstly, points adjacency is constructed through minimal search based on scan line. Connected component labeling algorithm is applied to classify raw ALS points into ground and non-ground by utilizing the adjacency structure. Then, some small objects are removed by morphology filtering, and isolated ground points are restored by IDW estimation. The experimental results shows that the method provides good filtering performance( about 97% accuracy) for diverse sites, and the overall processing takes less time than converting raw data into TIN or raster grid.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.47 no.3
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• pp.61-69
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• 2010

This paper presents an efficient object selection algorithm by analyzing and detecting of human activity. Generally, when people point any something, they will put a face on the target direction. Therefore, the direction of the face and fingers and was ordered to be connected to a straight line. At first, in order to detect the moving objects from the input frames, we extract the interesting objects in real time using background subtraction. And the judgment of movement is determined by Principal Component Analysis and a designated time period. When user is motionless, we estimate the user's indication by estimation in relation to vector from the head to the hand. Through experiments using the multiple views, we confirm that the proposed algorithm can estimate the movement and indication of user more efficiently.

• Journal of International Society for Simulation Surgery
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• v.1 no.1
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• pp.37-40
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• 2014

Purpose For living donor liver transplantation, liver segmentation is difficult due to the variability of its shape across patients and similarity of the density of neighbor organs such as heart, stomach, kidney, and spleen. In this paper, we propose an automatic segmentation of the liver using multi-planar anatomy and deformable surface model in portal phase of abdominal contrast-enhanced CT images. Method Our method is composed of four main steps. First, the optimal liver volume is extracted by positional information of pelvis and rib and by separating lungs and heart from CT images. Second, anisotropic diffusing filtering and adaptive thresholding are used to segment the initial liver volume. Third, morphological opening and connected component labeling are applied to multiple planes for removing neighbor organs. Finally, deformable surface model and probability summation map are performed to refine a posterior liver surface and missing left robe in previous step. Results All experimental datasets were acquired on ten living donors using a SIEMENS CT system. Each image had a matrix size of $512{\times}512$ pixels with in-plane resolutions ranging from 0.54 to 0.70 mm. The slice spacing was 2.0 mm and the number of images per scan ranged from 136 to 229. For accuracy evaluation, the average symmetric surface distance (ASD) and the volume overlap error (VE) between automatic segmentation and manual segmentation by two radiologists are calculated. The ASD was $0.26{\pm}0.12mm$ for manual1 versus automatic and $0.24{\pm}0.09mm$ for manual2 versus automatic while that of inter-radiologists was $0.23{\pm}0.05mm$. The VE was $0.86{\pm}0.45%$ for manual1 versus automatic and $0.73{\pm}0.33%$ for manaual2 versus automatic while that of inter-radiologist was $0.76{\pm}0.21%$. Conclusion Our method can be used for the liver volumetry for the pre-surgery planning of living donor liver transplantation.

• The Journal of the Korean dental association
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• v.53 no.5
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• pp.360-367
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• 2015

Purpose : The purpose of this study was to evaluate the effect of amount of cantilever in intra-crown according to implant fixture position on mechanical strength of internal conical joint type implant. Materials and Methods : Internal conical joint type implant fixture, abutment screw, abutment was connected and gold alloy prostheses were fabricated and cemented on abutment. For fatigue fracture test, the specimens were loaded to the 350 N, 2,000,000 cycle on 3, 4, 5, and 6 mm off-center of gold alloy prostheses. The fracture pattern of implant component was observed. Results : No fatigue fracture found on 3 and 4 mm group. But initial crack pattern found on 3 specimens of 4 mm group. Fatigue fracture found on all specimens of 5 mm group. But complete fracture was not observed. One specimen of 6 mm group fracture completely. Implant fixture fracture wax not observed. Conclusion : The mechanical failure of implant prostheses increased with the loading area farther from center of implant fixture. To reduce mechanical problem of internal joint type implant, surgical and prosthetic consideration is needed.

• Proceedings of the Korean Society of Plant Pathology Conference
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• 2003.10a
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• pp.76.1-76
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• 2003

The coat protein (CP) of Turnip crinkle virus (TCV) is organized into 3 distinct domains, R domain (RNA-binding) connected by an arm, 5 domain and P domain. We have previously shown that the CP of TCV strongly suppresses RNA silencing, and have mapped N-terminal R domain of which is also the elicitor of resistance response in the Arabidopsis ecotype Di-17 carrying the HRT resistance gene. In order to map the region in the TCV CP that is responsible for silencing suppression, a series of CP mutants were constructed, transformed into Agrobacterium, coinfiltrated either with HC-Pro (the helper component proteinase of tobacco etch potyvirus) known as a suppressor of PTGS or GFP constructs into leaves of Nicotiana benthmiana expressing GFP transgenically. In the presence of HC-Pro, all CP mutants were well protected, accumulating mutant CP mRNAs and their proteins even 5 days post-infiltration (DPI). In the presence of GFP, some mutant constructs which showed the accumulation of CP mutants and GFP mRNAs at early stage but eventually degraded at 5 DPI. Only a mutant which carrying 4 amino acid deletion of R domain was tolerable to maintain suppressing activity, suggesting that the suppressing activity is not directly related with the eliciting activity. A transient assay also revealed that the mutants synthesized their proteins, suggesting that a full length of CP sequences and its intact structure are required to stabilize CP, which suppresses the RNA silencing.

• Journal of Power System Engineering
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• v.20 no.4
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• pp.32-37
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• 2016

This paper proposes two measurement methods for injured rate of fish surface using color image segmentation method based on K-means clustering algorithm and Otsu's threshold algorithm. To do this task, the following steps are done. Firstly, an RGB color image of the fish is obtained by the CCD color camera and then converted from RGB to HSI. Secondly, the S channel is extracted from HSI color space. Thirdly, by applying the K-means clustering algorithm to the HSI color space and applying the Otsu's threshold algorithm to the S channel of HSI color space, the binary images are obtained. Fourthly, morphological processes such as dilation and erosion, etc. are applied to the binary image. Fifthly, to count the number of pixels, the connected-component labeling is adopted and the defined injured rate is gotten by calculating the pixels on the labeled images. Finally, to compare the performances of the proposed two measurement methods based on the K-means clustering algorithm and the Otsu's threshold algorithm, the edge detection of the final binary image after morphological processing is done and matched with the gray image of the original RGB image obtained by CCD camera. The results show that the detected edge of injured part by the K-means clustering algorithm is more close to real injured edge than that by the Otsu' threshold algorithm.

• Korean Journal of Veterinary Research
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• v.55 no.3
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• pp.181-184
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• 2015

Ciliary rootlet coiled coil protein (CROCC), the structural component that originates from the basal body at the proximal end of the ciliary rootlet, plays a crucial role in maintaining the cellular integrity of ciliated cells. In the current study, we cloned Xenopus CROCC and performed the expression analysis. The amino acid sequence of Xenopus laevis was related to those of Drosophila, cow, goat, horse, chicken, mouse and human. Reverse transcription polymerase chain reaction analysis revealed that CROCC mRNA encoding a coiled coil protein was present maternally, as well as throughout early development. In situ hybridization indicated that CROCC mRNA occurred in the animal pole of embryo during gastrulation and subsequently in the presumptive neuroectoderm at the end of gastrulation. At tailbud stages, CROCC mRNA expression was localized in the anterior roof plate of the developing brain, pharyngeal epithelium connected to gills, esophagus, olfactory placode, intestine and nephrostomes of the pronephric kidney. Our study suggests that CROCC may be responsible for control of the development of various ciliated organs.

• JSTS:Journal of Semiconductor Technology and Science
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• v.10 no.3
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• pp.176- 184
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• 2010

A low-power inductorless 1:4 DEMUX and a 4:1 MUX for a 90 nm CMOS are presented. The DEMUX can be operated at a speed of 25 Gb/s with the power supply voltage of 1.05 V, and the power consumption is 8.9 mW. The area of the DEMUX core is $29\;{\times}\;40\;{\mu}m^2$. The operation speed of the 4:1 MUX is 13 Gb/s at a power supply voltage of 1.2 V, and the power consumption is 4 mW. The area of the MUX core is $30\;{\times}\;18\;{\mu}m^2$. The MUX/DEMUX mainly consists of differential pseudo-NMOS. In these MUX/DEMUX circuits, logic swing is nearly rail-to-rail, and a low $V_{dd}$. The component circuit is more scalable than a CML circuit, which is commonly used in a high-performance MUX/DEMUX. These MUX/DEMUX circuits are compatible with conventional CMOS logic circuit, and it can be directly connected to CMOS logic gates without logic level conversion. Furthermore, the circuits are useful for core-to-core interconnection in the system LSI or chip-to-chip communication within a multi-chip module, because of its low power, small footprint, and reasonable operation speed.