• 한국전산유체공학회:학술대회논문집
• /
• 한국전산유체공학회 2003년도 The Fifth Asian Computational Fluid Dynamics Conference
• /
• pp.179-180
• /
• 2003

• 한국원자력학회:학술대회논문집
• /
• 한국원자력학회 2002년도 추계학술발표회요약집
• /
• pp.112-112
• /
• 2002

• 대한설비공학회지:설비저널
• /
• 제26권4호
• /
• pp.282-289
• /
• 1997

• 태양에너지
• /
• 제13권2_3호
• /
• pp.120-132
• /
• 1993

본 연구의 목적은 터어빈 회전차를 모델로한 복합회전형 히이트파이프의 전열특성을 실험과 유한요소의 해석법에 의하여 연구한 것이다. 입열량과 회전수에 따른 Nu, Re, Pr 그리고 무차원 응축액막두께가 변수로 사용되었다. 해석과 실험치는 거의 유사한 경향으로 일치하였으며, 연구결과는 복합히이트파이프 성능예측을 하는데 도움을 주었다. 복합회전형 히이트파이프에서의 열저항은 응축액막두께가 감소함에 따라 응축부의 열전달은 급격히 증가하였고, 응축액막두께는 복합회전형 히이트파이프의 전열 특성에 가장 큰 영향을 주었다. 주어진 Pr에서 Re가 변화함에 따라 무차원 응축액막두께가 일정한값으로 나타났고,무차원 응축액막두께는 회전수의 역수의 제곱근에 비례하였다. 본 연구의 해석적 방법에 의해서 Nu=A$({\delta}({\omega}/v)^{-1/2}Re^B)$라는 식을 구했고, 이때 A=0.963, B=0.5025의 값을 얻었다.

• Environmental Analysis Health and Toxicology
• /
• 제30권
• /
• pp.14.1-14.7
• /
• 2015

Objectives Cigarette smoking is associated with carcinogenesis owing to the mutagenic and genotoxic effects of cigarette smoke. The aim of this study was to evaluate the mutagenic and genotoxic effects of Korean cigarettes using in vitro assays. Methods We selected 2 types of cigarettes (TL and TW) as benchmark Korean cigarettes for this study, because they represent the greatest level of nicotine and tar contents among Korean cigarettes. Mutagenic potency was expressed as the number of revertants per ${\mu}g$ of cigarette smoke condensate (CSC) total particulate matter whereas genotoxic potency was expressed as a concentration-dependent induction factor. The CSC was prepared by the International Organization for Standardization 3308 smoking method. CHO-K1 cells were used in vitro micronucleus (MNvit) and comet assays. Two strains of Salmonella typhimurium (Salmonella enterica subsp. enterica ; TA98 and TA1537) were employed in Ames tests. Results All CSCs showed mutagenicity in the TA98 and TA1537 strains. In addition, DNA damage and micronuclei formation were observed in the comet and MNvit assays owing to CSC exposure. The CSC from the 3R4F Kentucky reference (3R4F) cigarette produced the most severe mutagenic and genotoxic potencies, followed by the CSC from the TL cigarette, whereas the CSC from the TW cigarette produced the least severe mutagenic and genotoxic potencies. Conclusions The results of this study suggest that the mutagenic and genotoxic potencies of the TL and TW cigarettes were weaker than those of the 3R4F cigarette. Further study on standardized concepts of toxic equivalents for cigarettes needs to be conducted for more extensive use of in vitro tests.

• Toxicological Research
• /
• 제26권4호
• /
• pp.329-337
• /
• 2010

Inhaled inorganic dusts, such as coal, can cause inflammation and fibrosis in the lungs, known as pneumoconiosis. Diagnosis of pneumoconiosis depends on morphological changes by radiological findings and functional change by pulmonary function test (PFT). Unfortunately, current diagnostic findings are limited only to lung fibrosis, which is usually irreversibly progressive. Therefore, it is important that research on potential and prospective biomarkers for pneumoconiosis should be conducted prior to initiation of irreversible radiological or functional changes in the lungs. Analytical techniques using exhaled breath condensate (EBC) or exhaled gas are non-invasive methods for detection of various respiratory diseases. The objective of this study is to investigate the relationship between inflammatory biomarkers, such as EBC pH or fractional exhaled nitric oxide ($FE_{NO}$), and pneumoconiosis among 120 retired coal miners (41 controls and 79 pneumoconiosis patients). Levels of EBC pH and FENO did not show a statistically significant difference between the pneumoconiosis patient group and pneumoconiosis patients with small opacity classified by International Labor Organization (ILO) classification. The mean concentration of $FE_{NO}$ in the low percentage $FEV_1$ (< 80%) was lower than that in the high percentage (80% $\leq$) (p = 0.023). The mean concentration of $FE_{NO}$ in current smokers was lower than that in non smokers (never or past smokers) (p = 0.027). Although there was no statistical significance, the levels of $FE_{NO}$ in smokers tended to decrease, compared with non smokers, regardless of pneumoconiosis. In conclusion, there was no significant relationship between the level of EBC pH or $FE_{NO}$ and radiological findings or PFT. The effects between exhaled biomarkers and pneumoconiosis progression, such as decreasing PFT and exacerbation of radiological findings, should be monitored.

• Nuclear Engineering and Technology
• /
• 제23권3호
• /
• pp.299-305
• /
• 1991

복수기를 통한 해수유입은 증기발생기내에 부식환경을 조성시키게 한다. 이론적 분석을 통하여 복수기누설시에 해수증의 불순물인 염소가 2차계통내에 누적되는 경향을 영광원전을 모델로하여 평가하였다. 분석결과 해수누설시에 고농도의 염소가 증기발생기내에 누적되는 것으로 나타났으나, 이는 증기 발생기내의 수질을 산성분위 기로 조성시킬 것으로 판단되었다. 복수기의 최대허용 설계누설(0.5 gpm)시에는 증기발생기 취출수량을 최대로 늘리고, 복수기정화계통을 가동하더라도 증기발생기에 2.3 ppm 및 복수기집수정에 0.6 ppm의 염소가 누적되는 것으로 나타났다. 또한 증기발생기에서의 염소농축계수는 아래와 같이 전적으로 취출수량 및 정화계통효율에만 의존하는 것으로 나타났으며,（equation omitted）취출수 및 정화계통은 2차계통내의 불순물을 제거하는데 효과적인 것으로 평가되었다.

• Safety and Health at Work
• /
• 제5권2호
• /
• pp.91-96
• /
• 2014

Background: Chronic obstructive pulmonary disease (COPD) is an important cause of occupational mortality in miners exposed to coal mine dust. Although the inflammatory mediators involved in COPD have not been defined, many studies have shown that inflammatory mediators such as reactive oxygen and nitrogen species are involved in orchestrating the complex inflammatory process in COPD. Methods: To investigate the relevance of exhaled biomarkers of oxidative and nitrosative stress in participants with COPD, we determined the levels of hydrogen peroxide, malondialdehyde (MDA), and 3-nitrotyrosine (3-NT) in exhaled breath condensate (EBC) in 90 retired elderly coal miners (53 non-COPD and 37 COPD participants). Results: Mean levels of MDA (4.64 nMvs. 6.46 nM, p = 0.005) and 3-NT (3.51 nMvs. 5.50 nM, p = 0.039) in EBC were significantly higher in participants with COPD. The median level of MDA did show statistical difference among the COPD severities (p = 0.017), and the area under the receiver operating characteristic curve forMDA (0.67) for the diagnostic discrimination of COPD indicated the biomarker. The optimal cutoff values were 5.34 nM (64.9% sensitivity and 64.2% specificity) and 5.58 nM (62.2% sensitivity and 62.3% specificity) forMDA and 3-NT, respectively. The results suggest that high levels ofMDA and 3-NT in EBC are associated with COPD in retired elderly miners. Conclusion: These results showed that the elevated levels of EBC MDA and EBC 3-NT in individuals with COPD are biomarkers of oxidative or nitrosative stress.

• 콘크리트학회지
• /
• 제7권5호
• /
• pp.189-199
• /
• 1995

나프탈렌술폰산 축합물( NSF) 은 시멘트 콘크리트용 고유동화제로 널리 사용되어 왔으나 경시에 따른 슬럼프 손실이 크다는 단점을 가지고 있다. NSF의 단독사용에 따른 이러한 단점을 보완하고자 유동성 유지의 서방성 기능을 지닌 무수말레인산-아크릴산의 폴리카르본산계 공중합체( MA)를 합성하였다. 합성한 MA를 NSF와 일정비율로 혼합하고 시멘트 페이스트에 적용하여 유동성 및 경시에 다른 유동성 유지성능과 유변학적 거동, 재령별 몰탈의 압축강도를 측정하여 물성에 미치는 영향을 살펴보았다. NSF에 MA를 각각 10,20 wt%씩 첨가한 NM-2가 우수한 유동성 및 유지성능을 보였으며, 유변학적 특성에서도 경과시간에 따른 전단응력 및 점도의 증가현상이 NSF단독 첨가에 비하여 지연됨으로써 시멘트 페이스트의 급격한 슬럼프 손실이 억제됨을 보여주었다. 또한 이러한 특성들은 혼화제의 투입량 및 물-시멘트비( W/C) 의 증감에 의해서도 영향을 받고 있다.

• 한국약용작물학회:학술대회논문집
• /
• 한국약용작물학회 2011년도 춘계학술발표회
• /
• pp.266-267
• /
• 2011