• Title/Summary/Keyword: Computer-simulation

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Development of $^{166}Ho$-Stent for the Treatment of Esophageal Cancer (식도암 치료용 $^{166}Ho$-Stent 개발)

  • Park, Kyung-Bae;Kim, Young-Mi;Kim, Kyung-Hwa;Shin, Byung-Chul;Park, Woong-Woo;Han, Kwang-Hee;Chung, Young-Ju;Choi, Sang-Mu;Lee, Jong-Doo
    • The Korean Journal of Nuclear Medicine
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    • v.34 no.1
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    • pp.62-73
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    • 2000
  • Purpose: Esophageal cancer patients have a difficulty in the intake of meals through the blocked esophageal lumen, which is caused by an ingrowth of cancer cells and largely influences on the prognosis. It is reported that esophageal cancer has a very low survival rate due to the lack of nourishment and immunity as the result of this. In this study a new radioactive stent, which prevents tumor ingrowth and restenosis by additional radiation treatment, has been developed. Materials and Methods: Using ${\ulcorner}HANARO{\lrcorner}$ research reactor, the radioactive stent assembly ($^{166}Ho$-SA) was prepared by covering the metallic stent with a radioactive sleeve by means of a post-irradiation and pre-irradiation methods. Results: Scanning electron microscopy and autoradiography exhibited that the distribution of $^{165/166}Ho\;(NO_3)$ compounds in polyurethane matrix was homogeneous. A geometrical model of the esophagus considering its structural properties, was developed for the computer simulation of energy deposition to the esophageal wall. The dose distributions of $^{166}Ho$-stent were calculated by means of the EGS4 code system. The sources are considered to be distributed uniformly on the surface in the form of a cylinder with a diameter of 20 mm and length of 40 mm. As an animal experiment, when radioactive stent developed in this study was inserted into the esophagus of a Mongrel dog, tissue destruction and widening of the esophageal lumen were observed. Conclusion: We have developed a new radioactive stent comprising of a radioactive tubular sleeve covering the metallic stent, which emits homogeneous radiation. If it is inserted into the blocked or narrowed lumen, it can lead to local destruction of the tumor due to irradiation effect with dilatation resulting from self-expansion of the metallic property. Accordingly, it is expected that restenosis esophageal lumen by the continuous ingrowth and infiltration of cancer after insertion of our radioactive stent will be decreased remarkably.

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Geoacoustic characteristics of Quaternary stratigraphic sequences in the mid-eastern Yellow Sea (황해 중동부 제4기 퇴적층의 지음향 특성)

  • Jin, Jae-Hwa;Jang, Seong-Hyeong;Kim, Seong-Pil;Kim, Hyeon-Tae;Lee, Chi-Won;Chang, Jeong-Hae;Choi, Jin-Hyeok;Ryang, Woo-Heon
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.6 no.2
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    • pp.81-92
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    • 2001
  • According to analyses of high-resolution seismic profiles (air gun, sparker, and SBP) and a deep-drill core(YSDP 105) in the mid-eastern Yellow Sea, stratigraphic and geoacoustic models have been established and seismo-acoustic modeling has been fulfilled using ray tracing of finite element method. Stratigraphic model reflects seismo-, litho-, and chrono-stratigraphic sequences formed under a significant influence of Quaternary glacio-eustatic sea-level fluctuations. Each sequence consists of terrestrial to very-shallow-marine coarse-grained lowstand systems tract and tidal fine-grained transgressive to highstand systems tract. Based on mean grain-size data (121 samples) of the drill core, bulk density and P-wave velocity of depositional units have been inferred and extrapolated down to a depth of the recovery using the Hamilton's regression equations. As goo-acoustic parameters, the 121 pairs of bulk density and P-wave velocity have been averaged on each unit of the stratigraphic model. As a result of computer ray-tracing simulation of the subsurface strata, we have found that there are complex ray paths and many acoustic-shadow zones owing to the presence of irregular layer boundaries and low-velocity layers.

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The Effects of amino acid balance on heat production and nitrogen utilization in broiler chickens : measurement and modeling

  • Kim, Jj-Hyuk;MacLeod, Murdo G.
    • Proceedings of the Korea Society of Poultry Science Conference
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    • 2004.11a
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    • pp.80-90
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    • 2004
  • Three experiments were performed to test the assumption that imbalanced dietary amino acid mixtures must lead to increased heat production (HP). The first experiment was based on diets formulated to have a wide range of crude protein (CP) concentrations but a fixed concentration of lysine, formulated to be the first-limiting amino acid. In the second (converse) experiment, lysine concentration was varied over a wide range while CP content was kept constant. To prevent the masking of dietary effects by thermoregulatory demands, the third experiment was performed at 30 $^{\circ}C$ with the diets similar to the diets used in the second experiment. The detailed relationships among amino acid balance, nitrogen (N) metabolism and energy (E) metabolism were investigated in a computer-controlled chamber calorimetry system. The results of experiments were compared with the predictions of a computerised simulation model of E metabolism. In experiment 1. with constant lysine and varying CP, there was a 75 % increase in N intake as CP concentration increased. This led to a 150 % increase in N excretion. with no significant change in HP. Simulated HP agreed with the empirically determined results in not showing a trend with dietary CP. In experiment 2, with varying lysine but constant CP, there was a 3-fold difference in daily weight gain between the lowest and highest lysine diets. HP per bird increased significantly with dietary lysine concentration. There was still an effect when HP was adjusted for body weight differences, but it failed to maintain statistical significance. Simulated HP results agreed in showing little effect of varying lysine concentration and growth rate on HP. Based on the results of these two experiments, the third experiment was designed to test the response of birds to dietary lysine in high ambient temperature. In experiment 3 which performed at high ambient temperature (30 $^{\circ}C$), HP per bird increased significantly with dietary lysine content, whether or not adjusted for body-weight. The trend was greater than in the previous experiment (20 $^{\circ}C$).

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Energy-Efficient Division Protocol for Mobile Sink Groups in Wireless Sensor Network (무선 센서 네트워크에서 이동 싱크 그룹의 분리를 지원하기 위한 라우팅 프로토콜)

  • Jang, Jaeyoung;Lee, Euisin
    • KIPS Transactions on Computer and Communication Systems
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    • v.6 no.1
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    • pp.1-8
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    • 2017
  • Communications for mobile sink groups such as rescue teams or platoons bring about a new challenging issue for handling mobility in wireless sensor networks. To do this, many studies have been proposed to support mobile sink groups. When closely looking at mobile sink groups, they can be divided into (multiple) small groups according to the property of applications. For example, a platoon can be divided into multiple squads to carry out its mission in the battle field. However, the previous studies cannot efficiently support the division of mobile sink groups because they do not address three challenging issues engendered by the mobile sink group division. The first issue is to select a leader sink for a new small mobile sink group. The efficient data delivery from a source to small mobile sink groups is the second issue. Last, the third issue is to share data between leader sinks of small mobile sink groups. Thus, this paper proposes a routing protocol to efficiently support the division of mobile sink groups by solving the three challenging issues. For the first issue, the proposed protocol selects a leader sink of a new small mobile sink group which provide a minimum summation of the distance between the new leader sink and the previous leader sink and the distance from the new leader sink to all of its member sinks. For the efficient data delivery from a source to small mobile sink groups in the second issue, the proposed protocol determines the path to minimize the data dissemination distance from source to small mobile sink group by calculating with the location information of both the source and the leader sinks. With regard to the third issue, the proposed protocol exploits member sinks located among leader sinks to provide efficient data sharing among leaders sinks by considering the location information of member sinks. Simulation results verified that the proposed protocol is superior to the previous protocol in terms of the energy consumption.

Analysis of Quantization Noise in Magnetic Resonance Imaging Systems (자기공명영상 시스템의 양자화잡음 분석)

  • Ahn C.B.
    • Investigative Magnetic Resonance Imaging
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    • v.8 no.1
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    • pp.42-49
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    • 2004
  • Purpose : The quantization noise in magnetic resonance imaging (MRI) systems is analyzed. The signal-to-quantization noise ratio (SQNR) in the reconstructed image is derived from the level of quantization in the signal in spatial frequency domain. Based on the derived formula, the SQNRs in various main magnetic fields with different receiver systems are evaluated. From the evaluation, the quantization noise could be a major noise source determining overall system signal-to-noise ratio (SNR) in high field MRI system. A few methods to reduce the quantization noise are suggested. Materials and methods : In Fourier imaging methods, spin density distribution is encoded by phase and frequency encoding gradients in such a way that it becomes a distribution in the spatial frequency domain. Thus the quantization noise in the spatial frequency domain is expressed in terms of the SQNR in the reconstructed image. The validity of the derived formula is confirmed by experiments and computer simulation. Results : Using the derived formula, the SQNRs in various main magnetic fields with various receiver systems are evaluated. Since the quantization noise is proportional to the signal amplitude, yet it cannot be reduced by simple signal averaging, it could be a serious problem in high field imaging. In many receiver systems employing analog-to-digital converters (ADC) of 16 bits/sample, the quantization noise could be a major noise source limiting overall system SNR, especially in a high field imaging. Conclusion : The field strength of MRI system keeps going higher for functional imaging and spectroscopy. In high field MRI system, signal amplitude becomes larger with more susceptibility effect and wider spectral separation. Since the quantization noise is proportional to the signal amplitude, if the conversion bits of the ADCs in the receiver system are not large enough, the increase of signal amplitude may not be fully utilized for the SNR enhancement due to the increase of the quantization noise. Evaluation of the SQNR for various systems using the formula shows that the quantization noise could be a major noise source limiting overall system SNR, especially in three dimensional imaging in a high field imaging. Oversampling and off-center sampling would be an alternative solution to reduce the quantization noise without replacement of the receiver system.

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Analysis of Trading Performance on Intelligent Trading System for Directional Trading (방향성매매를 위한 지능형 매매시스템의 투자성과분석)

  • Choi, Heung-Sik;Kim, Sun-Woong;Park, Sung-Cheol
    • Journal of Intelligence and Information Systems
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    • v.17 no.3
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    • pp.187-201
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    • 2011
  • KOSPI200 index is the Korean stock price index consisting of actively traded 200 stocks in the Korean stock market. Its base value of 100 was set on January 3, 1990. The Korea Exchange (KRX) developed derivatives markets on the KOSPI200 index. KOSPI200 index futures market, introduced in 1996, has become one of the most actively traded indexes markets in the world. Traders can make profit by entering a long position on the KOSPI200 index futures contract if the KOSPI200 index will rise in the future. Likewise, they can make profit by entering a short position if the KOSPI200 index will decline in the future. Basically, KOSPI200 index futures trading is a short-term zero-sum game and therefore most futures traders are using technical indicators. Advanced traders make stable profits by using system trading technique, also known as algorithm trading. Algorithm trading uses computer programs for receiving real-time stock market data, analyzing stock price movements with various technical indicators and automatically entering trading orders such as timing, price or quantity of the order without any human intervention. Recent studies have shown the usefulness of artificial intelligent systems in forecasting stock prices or investment risk. KOSPI200 index data is numerical time-series data which is a sequence of data points measured at successive uniform time intervals such as minute, day, week or month. KOSPI200 index futures traders use technical analysis to find out some patterns on the time-series chart. Although there are many technical indicators, their results indicate the market states among bull, bear and flat. Most strategies based on technical analysis are divided into trend following strategy and non-trend following strategy. Both strategies decide the market states based on the patterns of the KOSPI200 index time-series data. This goes well with Markov model (MM). Everybody knows that the next price is upper or lower than the last price or similar to the last price, and knows that the next price is influenced by the last price. However, nobody knows the exact status of the next price whether it goes up or down or flat. So, hidden Markov model (HMM) is better fitted than MM. HMM is divided into discrete HMM (DHMM) and continuous HMM (CHMM). The only difference between DHMM and CHMM is in their representation of state probabilities. DHMM uses discrete probability density function and CHMM uses continuous probability density function such as Gaussian Mixture Model. KOSPI200 index values are real number and these follow a continuous probability density function, so CHMM is proper than DHMM for the KOSPI200 index. In this paper, we present an artificial intelligent trading system based on CHMM for the KOSPI200 index futures system traders. Traders have experienced on technical trading for the KOSPI200 index futures market ever since the introduction of the KOSPI200 index futures market. They have applied many strategies to make profit in trading the KOSPI200 index futures. Some strategies are based on technical indicators such as moving averages or stochastics, and others are based on candlestick patterns such as three outside up, three outside down, harami or doji star. We show a trading system of moving average cross strategy based on CHMM, and we compare it to a traditional algorithmic trading system. We set the parameter values of moving averages at common values used by market practitioners. Empirical results are presented to compare the simulation performance with the traditional algorithmic trading system using long-term daily KOSPI200 index data of more than 20 years. Our suggested trading system shows higher trading performance than naive system trading.

Software Reliability Growth Modeling in the Testing Phase with an Outlier Stage (하나의 이상구간을 가지는 테스팅 단계에서의 소프트웨어 신뢰도 성장 모형화)

  • Park, Man-Gon;Jung, Eun-Yi
    • The Transactions of the Korea Information Processing Society
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    • v.5 no.10
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    • pp.2575-2583
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    • 1998
  • The productionof the highly relible softwae systems and theirs performance evaluation hae become important interests in the software industry. The software evaluation has been mainly carried out in ternns of both reliability and performance of software system. Software reliability is the probability that no software error occurs for a fixed time interval during software testing phase. These theoretical software reliability models are sometimes unsuitable for the practical testing phase in which a software error at a certain testing stage occurs by causes of the imperfect debugging, abnornal software correction, and so on. Such a certatin software testing stage needs to be considered as an outlying stage. And we can assume that the software reliability does not improve by means of muisance factor in this outlying testing stage. In this paper, we discuss Bavesian software reliability growth modeling and estimation procedure in the presence of an imidentitied outlying software testing stage by the modification of Jehnski Moranda. Also we derive the Bayes estimaters of the software reliability panmeters by the assumption of prior information under the squared error los function. In addition, we evaluate the proposed software reliability growth model with an unidentified outlying stage in an exchangeable model according to the values of nuisance paramether using the accuracy, bias, trend, noise metries as the quantilative evaluation criteria through the compater simulation.

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A Way for Creating Human Bioclimatic Maps using Human Thermal Sensation (Comfort) and Applying the Maps to Urban and Landscape Planning and Design (인간 열환경 지수를 이용한 생기후지도 작성 및 도시·조경계획 및 디자인에의 적용방안)

  • Park, Soo-Kuk
    • Journal of the Korean Institute of Landscape Architecture
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    • v.41 no.1
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    • pp.21-33
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    • 2013
  • The purpose of this study is to find applicabilities of human bioclimatic maps, using human thermal sensation(comfort) in summer, with microclimatic in situ data and computer simulation results at the study site of downtown Daegu. This includes the central business district(CBD) area and two urban parks, the Debt Redemption Movement Memorial Park and the 2.28 Park, for urban and landscape planning and design. Climatic data and urban setting information for the analysis of human thermal sensation were obtained from in situ measurement and the geographic information system data. As a result, the CBD had higher air temperature than the parks when the wind speed was low. Relative humidities were opposite to the air temperature. Especially, same directional streets with local wind direction had lower air temperature than streets perpendicular to the wind direction. The most important climatic variable of human thermal sensation in summer was direct beam solar radiation. Also, creating shadow areas would be the most relevant method for modifying hot thermal environments in urban areas. The most effective method of creating shadow patterns was making a tree shadow over a pergola, and the second best one was making a tree shadow on the front of north directional building walls. Moreover, how to plant trees for creating shadow patterns was important as well as what kind of trees should be planted. The results of human thermal sensation were warm to very hot at sunny areas and neutral to warm at shaded ones. At the sunny areas, wide, squared shape areas had a little bit higher thermal sensation than those of narrow streets. The albedo change of building walls 0.15 and ground surface 0.1 could change 1/6 of a sensation level at the shaded areas and 1/3 at the sunny ones. These microclimatic approaches will be useful to find appropriate methods for modifying thermal environments in urban areas.

A Study on the Application Direction of Finite Element Analysis in the Field of Packaging through Research Trend Analysis in Korea (국내 연구 동향 분석을 통한 포장분야에서 유한요소해석의 적용 방향에 관한 고찰)

  • Lee, Hakrae;Jeon, Kyubae;Ko, Euisuk;Shim, Woncheol;Kang, Wookgun;Kim, Jaineung
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.23 no.3
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    • pp.191-200
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    • 2017
  • Proper packaging design can meet both the environmental and economic aspects of packaging materials by reducing the use of packaging materials, waste generation, material costs, and logistics costs. Finite element analysis(FEM) is used as a useful tool in various fields such as structural analysis, heat transfer, fluid motion, and electromagnetic field, but its application in the field of packaging is still insufficient. Therefore, the application of FEM to the field of packaging can save the cost and time in the future research because it is possible to design the package by computer simulation, and it is possible to reduce the packaging waste and logistics cost through proper packaging design. Therefore, this study investigated the FEM papers published in Korea for the purpose of helping research design using FEM program in the field of packaging in the future. In this paper, we analyzed the 29 papers that were directly related to the analysis of FEM papers published in domestic journals from 1991 to 2017. As a result, we analyzed the research topic, FEM program, and analysis method using each paper, and presented the direction that can be applied in future packaging field. When the FEM is applied to the packaging field, it is possible to change the structure and reduce the thickness through the stress and vibration analysis applied to the packaging material, thereby reducing the cost by improving the mechanical strength and reducing the amount of the packaging material. Therefore, in the field of packaging research in the future, if the FEM is performed together, economical and reasonable packaging design will be possible.

Preliminary Study on the MR Temperature Mapping using Center Array-Sequencing Phase Unwrapping Algorithm (Center Array-Sequencing 위상펼침 기법의 MR 온도영상 적용에 관한 기초연구)

  • Tan, Kee Chin;Kim, Tae-Hyung;Chun, Song-I;Han, Yong-Hee;Choi, Ki-Seung;Lee, Kwang-Sig;Jun, Jae-Ryang;Eun, Choong-Ki;Mun, Chi-Woong
    • Investigative Magnetic Resonance Imaging
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    • v.12 no.2
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    • pp.131-141
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    • 2008
  • Purpose : To investigate the feasibility and accuracy of Proton Resonance Frequency (PRF) shift based magnetic resonance (MR) temperature mapping utilizing the self-developed center array-sequencing phase unwrapping (PU) method for non-invasive temperature monitoring. Materials and Methods : The computer simulation was done on the PU algorithm for performance evaluation before further application to MR thermometry. The MR experiments were conducted in two approaches namely PU experiment, and temperature mapping experiment based on the PU technique with all the image postprocessing implemented in MATLAB. A 1.5T MR scanner employing a knee coil with $T2^*$ GRE (Gradient Recalled Echo) pulse sequence were used throughout the experiments. Various subjects such as water phantom, orange, and agarose gel phantom were used for the assessment of the self-developed PU algorithm. The MR temperature mapping experiment was initially attempted on the agarose gel phantom only with the application of a custom-made thermoregulating water pump as the heating source. Heat was generated to the phantom via hot water circulation whilst temperature variation was observed with T-type thermocouple. The PU program was implemented on the reconstructed wrapped phase images prior to map the temperature distribution of subjects. As the temperature change is directly proportional to the phase difference map, the absolute temperature could be estimated from the summation of the computed temperature difference with the measured ambient temperature of subjects. Results : The PU technique successfully recovered and removed the phase wrapping artifacts on MR phase images with various subjects by producing a smooth and continuous phase map thus producing a more reliable temperature map. Conclusion : This work presented a rapid, and robust self-developed center array-sequencing PU algorithm feasible for the application of MR temperature mapping according to the PRF phase shift property.

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