• BMB Reports
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• 제39권3호
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• pp.240-246
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• 2006

The base compositional correlations that hold among various coding and noncoding regions of the canine genome have been analysed. The distribution pattern of genes, on the basis of $GC_3$ composition, shows a wide range similar to that observed in human. However the occurrence of maximum number of genes was observed in the range of 65-75% of $GC_3$ composition. The correlation between the coding DNA sequences of canine with the different noncoding regions (introns and flanking regions) is found to be significant and in many cases the degree of correlation show similarity to human genome. We found that these correlations are not limited to the GC content alone, but is holding at the level of the frequency of individual bases as well. The present study suggests that canines ideally belong to the predicted 'general mammalian pattern' of genome composition along with human beings.

• Communications for Statistical Applications and Methods
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• 제29권4호
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• pp.453-469
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• 2022

The study of immune cellular composition has been of great scientific interest in immunology because of the generation of multiple large-scale data. From the statistical point of view, such immune cellular data should be treated as compositional. In compositional data, each element is positive, and all the elements sum to a constant, which can be set to one in general. Standard statistical methods are not directly applicable for the analysis of compositional data because they do not appropriately handle correlations between the compositional elements. In this paper, we review statistical methods for compositional data analysis and illustrate them in the context of immunology. Specifically, we focus on regression analyses using log-ratio transformations and the alternative approach using Dirichlet regression analysis, discuss their theoretical foundations, and illustrate their applications with immune cellular fraction data generated from colorectal cancer patients.

• 한국가금학회지
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• 제25권1호
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• pp.11-19
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• 1998

This study was conducted to estimate the heritabilities and genetic correlations on egg weight and egg compositional traits for breeding plan and selection in Korean native chicken. Data analyzed were the records of 46,908 eggs from 430 layers produced from 180 dam and 26 sire families, from April, 1994 to September, 1995. On egg weight and egg compositional traits at 1st egg, 300 and 500 days of age, the egg weights were 41.489, 49.544 and 52.770g ; the albumin weights were 25.953, 29.979 and 31.288g; the yolk weights were 11.091, 14.541 and 16.368g; shell weights were 4.472, 5.037 and 5.099g, respectively. The estimates of heritability of egg weights and egg compositional traits based on the variance of sires, dams and combined components at 300 days of age were 0.214, 0.226 and 0.720 for egg weight ; 0.307, 0.152 and 0.730 for albumin weight ; 0.124, 0.953 and 0.699 for yolk weight ; 0.047, 0.026 and 0.536 for shell weight. The genetic correlation coefficient between egg weight and albumen weight was 0.083~0.951 ; 0.310~0.507 between egg weight and yolk weight ; 0.242~0.523 between egg weight and shell weight ; 0. 237~0. 413 between albumen weight and yolk weight ; 0.232~0.449 between albumen weight and shell weight ; -0.264~0.239 between yolk weight and shell weight, respectively.

• 암석학회지
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• 제27권2호
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• pp.73-84
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• 2018

청송 북부에는 청송 암맥군, 중태산 병반과 갈평지 암주 등의 화성관입체를 산출한다. 청송 암맥군은 다양한 구과를 발달시키는 유문암질 암맥들로 구성된다. 암맥들의 분포는 갈평지 암주를 중심으로 기하학적으로 방사상 패턴을 나타낼 뿐만 아니라, 관입체들의 화학조성은 암맥군의 공급원을 지시한다. 여기서 우리는 3개 관입체로부터 28개의 시료에 대한 조성적 자료를 보고한다. 관입체들은 같은 유문암질 조성이지만, 조성대비에 의하면, 관입체 조성 간에 상당히 중첩된다. 특히 청송 암맥군은 암석 색깔에 의해 몇몇 암맥그룹으로 구분되고 조성 다양성을 나타내지만, 대체로 기타 관입암 조성과 중첩을 나타낸다. 중태산 병반은 청송 암맥군과 비교하면 알칼리, $K_2O$와 $Al_2O_3$이 더 풍부하며 $Fe_2O_3{^t}$, $TiO_2$과 REE가 더 고갈되어 있다. 이와 대조적으로, 갈평지 암주는 화학조성이 더 좁은 범위를 나타내며, 청송 암맥군과 흔히 예리한 조성중첩을 가진다. 이러한 조성대비에 의하면 갈평지 암주는 조성적으로 청송 암맥군의 공급원으로 판단되며 화산작용의 에피소드로 연결된다고 생각된다.

• Genomics & Informatics
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• 제14권4호
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• pp.234-240
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• 2016

Different mechanisms, including transcriptional and post transcriptional processes, regulate tissue specific expression of genes. In this study, we report differences in gene/protein compositional features between apoptosis involved genes selectively expressed in human tissues. We found some correlations between codon/amino acid usage and tissue specific expression level of genes. The findings can be significant for understanding the translational selection on these features. The selection may play an important role in the differentiation of human tissues and can be considered for future studies in diagnosis of some diseases such as cancer.

• Journal of Nutrition and Health
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• 제31권6호
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• pp.1057-1065
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• 1998

Anthropometric and body compositional changes and the outcomes of the pregnancies of 90 healthy Korean women were investigated in a longitudinal study. Their weight increased from 51.3$\pm$5.9kg to 65.1$\pm$7.8kg during their pregnancies. The total weight gain was 13.8$\pm$4.5kg, and therefore, weekly weight gain was 340$\pm$110g during the entire period of the pregnancy. The weight gain was composed of approximately 50-60% fat mass and 40-50% fat-free mass. Skinfold thicknesses, both of triceps and subscapular, increased during the pregnancies. The fat mass calculated from skinfold thickness and that measured with bioelectrical impedance analysis went on increasing during the pregnancies. Although there was a considerable difference with respect to the fat mass observed using the three methods, fat mass gain was 5.0-6.1kg and fat-free mass gain was 4.0-5.3kg from the first trimester to the third trimester of pregnancies. There were significant correlations between maternal anthropometric parameters and indices of pregnancy outcomes. Especially, the infant's birth weight was associated with maternal pre-pregnancy weight and weight gains during the pregnancies. The infant's birth length was related to the maternal weight observed at term(p<0.05) and weight gain during the entire pregnancies (p<0.05) . Neither increase of fat mass nor fat-free mass affected the outcomes of pregnancy. These results show that maternal weight gain during pregnancy is led by increments of approximately above 50% fat mass. The fat mass increase seems to be larger in central areas than in subcutaneous areas. Maternal weight gain during pregnancy, especially during late pregnancy, is a factor affecting the birth weight and length of infant. On the basis of the body compositional changes, it can be predicted that the additional energy requirement for pregnancy in Korean women is more than 200-230 MJ (64,500-76,250kca1). (Korean J Nutrition 31(6) : 1057-1065, 1998)

• 자원환경지질
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• 제16권1호
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• pp.1-10
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• 1983

The Yeonhwa (I, II) and Keodo mines, neighboring in the middle part of the Taebaegsan mineral belt, contain three distinct classes of skarn deposits: the zinc-lead skarn at Yeonhwa (I, II), the iron skarn at Keodo south (Jangsan orebodies), and the copper skarn at Keodo north (78 orebodies). The present study characterizes the three classes of skarn deposits mainly in terms of skarn/ore associations examined from chemical compositional point of view, and applies existing quantitative phase diagrams to some pertinent mineral assemblages in these mines. At Yeonhwa I the Wolam I orebody shows a vertical variation in skarn minerals ranging from clinopyroxene/garnet zone on the lower levels through clinopyroxene (without garnet) zone on the intermediate levels, and finally to rhodochrosite veins on the upper levels and surface. Ore minerals, sphalerite and galena, associate most closely with the intermediate clinopyroxene zone. At Keodo, the Jangsan iron skarn hosted in quartz monzodiolite as a typical endoskarn, shows a skarn zoning, from center of orebody to outer side, magnetite zone, magnetite/garnet zone, garnet clinopyroxene zone, and clinopyroxene/epidote/plagioclase zone. The 78 copper skarn in the Hwajeol limestone indicates a zoning, from quartz porphyry side toward limestone side, orthoclase/epidote zone, epidote/clinopyroxene zone, and clinopyroxene/garnet zone; chalcopyrite and other copper sulfides tend to be in clinopyroxene/garnet zone. Mioroprobe analyses of clinopyroxenes and garnets from the various skarn zones mentioned above revealed that the Yeonhwa zinc/lead skarns are characterized by johansenitic clinopyroxene (Hd 25-78, Jo 15-23) and manganoan andraditic garnet (Ad 13-97, Sp 1-24), whereas the Jangsan iron skarn at Keodo by Mn-poor diopsidic clinopyroxene (Di 78-93, Jo 0.2-1.0) and Mn-poor grossularitic grandite (Gr 65-77, Sp 0.5-1.0). The 78 copper skarn at Keodo is characterized by Mn-poor diopsidic-salite (Di 66-91, Jo 0.2-1.1) and Mn-poor andraditic grandite(Ad 40-74, Sp 0.5-1.1). The compositional charateristics of iron, copper, and zinc-lead skarns in the Yeonhwa-Keodo mines are in good correlations with those of the foreign counterparts. Compiling a $T-XCO_2$ phase diagram for the Jangsan endoskarns, a potential upper limit of temperature of the main stage of skarn formation is estimated to be about $530^{\circ}C$, and a lower limit to be $400^{\circ}C$ or below assuming $XCO_2=0.05$ at P total=1kb. Applying a published log $fS_2$-log $fo_2$ diagram to the Keodo 78 and Yeonhwa exoskarns, it is revealed that copper sulfides and zinc-lead sulfides do not co-exist stably below log $fS_2=-4$ and log $fO_2=-23$ at $T=400^{\circ}C$ and ${\times}CO=1$ atm.

• 한국환경생태학회지
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• 제31권5호
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• pp.433-443
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• 2017

식생자료의 종조성적 온전성(전형성과 대표성) 확보는 Z.-M. 학파의 정제된 식생자료(phytosociological $relev\acute{e}$)와 식물군락(plant community)을 이용하는 국가식생자원에 대한 통합적 관리의 주요 선행 과정이다. 본 연구의 목적은 특정 단위식생으로 모둠화된 식생자료의 종조성 균질성에 대한 질적 양적 평가 도구를 개발하는 것이다. 식생자료의 이질적 요소가 적용된 새로운 균질도, 현존균질도(actual homotoneity: $H_{act}$)와 최적균질도(optimal homotoneity: $H_{opt}$)를 제안하였다. 사례 식생형에서 식물상 변수들, 새로 개발한 균질도, 선행연구의 유사 균질도(Pfeiffer's homogeneity, basic homotoneity-coefficient, corrected homotoneity-coefficient, mean floristic similarity)와의 상관관계는 Spearman 순위 상관계수(Spearman's rank correlation coefficient)로 분석되었다. 현존균질도와 최적균질도는 각각 식생자료 간과 단위식생 간의 식물상 균질성 차이를 더욱 분명하게 드러내었다. 식생자료수로부터 가장 독립적인 균질도는 현존균질도였다. 오랜 교란 역사를 지닌 한반도의 현존식생 조건에서 최적균질도는 현존균질도에 대한 더욱 정교한 해석이 가능한 보완적 수단이 되었다. 현존균질도와 최적균질도는 국가 식생자원에 대한 일관성과 객관성을 포함하는 식생자료의 DB 구축을 위한 균질한 식생자료 선별에 기여할 것으로 기대되었다.

• 자원환경지질
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• 제23권1호
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• pp.35-57
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• 1990

This study has been carried out on the Pegmatites, Naedeogri Granites, Nonggeori Granites and Metasedimentary rocks in the middle area of Taebaeksan region to investigate the geochemical properties and possibility of productivity. Pegmatites are characterized by metamorphosed anatectic pegmatite and differentiated magmatic pegmatite, and are mixed type of rare-element pegmatite and mica-bearing pegmatite by the classification of Ginsburg(1979). The petrological type of the igneous rocks is thought to be calcalkali, subalkaline and peralumious. According to chemical variations against D. I., differentiation trends from Naedeogri and Nonggeori Granites through non-mineralized pegmatites to mineralized pegmatites are supposed. From the relationship between oxided and $SiO_2$, pegmatites and Nonggeori Granite have shown similar tendencies and bulk composition of pegmatites and similar to metasedimentary rocks near the intrusives. By judging the correlations of trace elements, it is elucidated that pegmatites adjacent to Naedeogri and Nonggeori Granites have been originated in magma differentiation from these granites and the others have been differentiated by remelting or partial melting from metasedimentary rocks. $Sp_5$, $Sp_8$, and $Sp_9$ pegmatites are considered as productive rocks, and $Sp_4$, $Sp_6$, $Sp_7$, $Sp_{10}$, $Sp_{11}$, and $Sp_{12}$ pegmatites and granites are supposed to have a weak productivity, in terms of element ratios related with Sn mineralizations. Tourmalines in productive pegmatites are formed under the circumstance of Li-poor granitoids and associated with pegmatites, and the others are seemed to be originated in metapelites and metapsammites which are not coexisting with an Al-saturating phase. Three types of chemical zoning are noticed in tourmalines: (1) apparently homogeneous compositional patterns, (2) a continuous core-to-rim zoning and, (3) a discontinuous core-to-rim zoning. From results of EPMA of tourmalines, Al, Mg and Ca increase closer to rim, while Fe decreases.

• 한국지역지리학회지
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• 제20권2호
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• pp.217-229
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• 2014

본 연구는 건강을 설명하는 지역 박탈 지표를 선별하고 이러한 지표들이 근린사회의 인구구성효과와 구분되는 독립적인 맥락효과를 지니는지 검증해 보았다. 이를 위하여 서울시를 대상으로 행정동 단위의 표준화사망비를 산출하여 소지역 건강불평등 실태를 분석하였고, 표준화사망비 격차를 설명하는 지역박탈 지표들을 선정하였다. 그리고 다수 준 모형을 통해 개인의 사회경제적 지위를 통제한 후 지역박탈 효과를 검증하였다. 분석 결과는 건강불평등의 지역 격차가 대부분 사회경제적 지위 요인을 반영할 뿐이며, 거주지 지역사회의 독립된 맥락효과는 미미한 것으로 나타났다. 분석에서 행정동별 표준화사망비 분포가 취약근린지수의 분포와 유사하고 더 나아가 공시지가, 하위교육수준, 복지수급자 비율, 여성가구주 가구의 개별 지표 분포와 유사한 패턴을 보이고 있는 것으로 나타나 전반적으로 인구집단의 취약성을 반영하는 것으로 보인다. 반면 빈곤 지역이 내생적으로 형성하는 건강문화나 보건의료접근성 등의 가능한 매개 요인들의 가능성은 인구 구성에 따른 빈곤과 결핍보다 상대적으로 저조할 것으로 보인다. 즉 건강의 지역별 격차는 다름 아닌 계층간 격차로 해석될 수 있다.