• Title/Summary/Keyword: Component Identification

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Computer-Aided Diagnosis for Pulmonary Tuberculosis using Texture Features Analysis in Digital Chest Radiography (질감분석을 이용한 폐결핵의 자동진단)

  • Kim, Dae-Hun;Ko, Seong-Jin;Kang, Se-Sik;Kim, Jung-Hoon;Kim, Chang-Soo
    • The Journal of the Korea Contents Association
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    • v.11 no.11
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    • pp.185-193
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    • 2011
  • There is no exact standard of detecting pulmonary tuberculosis(TB) in digital image of simple chest radiography. In this study, I experimented on the principal components analysis(PCA) algorithm in the past and suggested six other parameters as identification of TB lesions. The purpose of this study was to develop and test computer aided diagnosis(detection) method for the detection and measurement of pulmonary abnormalities on digital chest radiography. It showed comparatively low recognition diagnosis rate using PCA method, however, six kinds of texture features parameters algorithm showed similar or higher diagnosis rates of pulmonary disease than that of the clinical radiologists. Proposed algorithms using computer-aided of texture analysis can distinguish between areas of abnormality in the chest digital images, differentiate lesions having pulmonary disease. The method could be useful tool for classifying and measuring chest lesions, it would play a major role in radiologist's diagnosis of disease so as to help in pre-reading diagnosis and prevention of pulmonary tuberculosis.

Identification of dietary patterns in urban population of Argentina: study on diet-obesity relation in population-based prevalence study

  • Pou, Sonia Alejandra;del Pilar Diaz, Maria;De La Quintana, Ana Gabriela;Forte, Carla Antonella;Aballay, Laura Rosana
    • Nutrition Research and Practice
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    • v.10 no.6
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    • pp.616-622
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    • 2016
  • BACKGROUND/OBJECTIVES: In Argentina, obesity prevalence rose from 14.6% in 2005 to 20.8% in 2013. Although the number of studies on noncommunicable diseases and dietary patterns as a unique dietary exposure measure has increased, information on this topic remains scarce in developing countries. This is the first population-based study investigating the association between diet and obesity using a dietary pattern approach in Argentina. We aimed (a) to identify current dietary patterns of the population of $C{\acute{o}}rdoba$ city, (b) to investigate its association with obesity prevalence, and (c) to identify and describe dietary patterns from the subgroup of people with obesity. SUBJECTS/METHODS: The $C{\acute{o}}rdoba$ Obesity and Diet Study (CODIES) was conducted in $C{\acute{o}}rdoba$ city by using a random sample of n = 4,327 subjects between 2005 and 2012. Empirically derived dietary patterns were identified through principal component factor analysis. A multiple logistic regression analysis was used to investigate the association of dietary patterns with obesity. RESULTS: Four dietary patterns were identified, called "Starchy-Sugar", "Prudent", "Western", and "Sugary drinks". High scores for the "Western" pattern (with strongest factor loading on meats/eggs, processed meats, and alcohol) showed a positive association with obesity (OR: 1.33, 95% CI: 1.06-1.67, for third versus first tertile of factor score). "Meats/Cheeses" and "Snacks/Alcohol" patterns emerged in people with obesity. CONCLUSIONS: The findings suggest that high adherence to the "Western" pattern promoted obesity in this urban population. In addition, people with obesity showed characteristic dietary patterns that differ from those identified in the overall population.

The Development of Motivation Scale in the Visual Artistic Giftedness of the Elementary School Children (학동기 시각예술영재성 동기요인 검사도구 개발)

  • 이용애
    • Proceedings of the Korean Society for the Gifted Conference
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    • 2003.05a
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    • pp.109-126
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    • 2003
  • The Purpose of this study was to develop the instruments which can measure motivation as a component of Visual Artistic Giftedness with in elementary school period. This study prescribed the variable factors of measurement after abstract and classify the characteristics of Visual Artistic Giftedness through literature studies. And it produced instruments those are finally composed of 27 items through the preliminary test. They were evaluated in terms of content validity, construct validity, and reliability by implementing them to 679 elementary school children from the first to sixth grades Statistical analyses were carried out to verify the validities and reliability. Content validity was found to be satisfactory by expert’s evaluation on the test items. Construct validity was also found to be satisfactory through factor analyses which showed the four factors which the identification instruments were intended to measure such as, interest/ attitude/ taste, endurance/ concentration, curiosity/ imagination/ sensitiveness, aesthetic Concurrent validity was also found to be satisfactory with high coeffients of Barron-Welsh which were calculated as .76 in motivation, In conclusion, the instruments about motivation of Visual Artistic Giftedness during elementary school period developed by this study are highly reliable on its reliability and validity.

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Molecular Identification and Chemical Analysis of Aconiti Kusnezoffii Tuber on the Domestic Markets (국내 시장에서 유통되는 초오의 DNA 감별과 화학적 분석)

  • Jang, Hyeri;Joe, Kyeong-Hwa;Song, Kwangho;Lee, Kyoung Jin;Park, Sait Byul;Lee, Chaemin;Ha, In Jin;Lee, Kyungjin;Suh, Youngbae;Kim, Yeong Shik
    • Korean Journal of Pharmacognosy
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    • v.49 no.2
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    • pp.145-154
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    • 2018
  • Aconiti Kusnezoffii Tuber has been traditionally used to treat the symptoms of rheumatoid arthritis and joint pain. The main constituents are diterpenoid alkaloids such as benzoylmesaconine, benzoylaconine, mesaconitine, aconitine, and hypaconitine. In Korea, Aconiti Kusnezoffii Tuber is officially defined as the tubers of Aconitum kusnezoffii Reichb., A. ciliare Decasisne, and A. triphyllum Nakai. On the other hand, only the tuber of A. kusnezoffii is to be used in China. In order to identify the botanical origin of Aconiti Kusnezoffii Tuber circulated in Korea, we analyzed 24 samples of Aconiti Kusnezoffii Tuber obtained from local markets for comparative DNA analysis. The sequence analysis of nrRNA ITS 1 was useful to distinguish Aconitum species and revealed that the roots of A. karakolicum were circulated in Korean markets without discretion. HPLC quantitative analysis showed that aconitine was detected at the highest amount in A. karakolicum. Authentic diterpenoid alkaloids were coinjected for quantification of aconitine-type ingredients. All data were statistically grouped by Principal Component Analysis (PCA). This study suggests that both molecular and chemical analyses should be utilized for the standardization and the quality control for Aconiti Kusnezoffii Tuber.

Identification of Salmonella Pathogen Using Electronic Nose (전자코를 이용한 살모넬라 식중독균 판정)

  • Kim G.;Lee M. W.;Lee K. J.;Choi C. H.;Noh K. M.;Kang S,;Chang Y. C.
    • Journal of Biosystems Engineering
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    • v.30 no.2 s.109
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    • pp.121-126
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    • 2005
  • In this study, a commercial electronic nose system was used to detect contamination of Salmonella bacteria. Odors from growth media contaminated with Salmonella typhimurium, Salmonella enteritidis, or Escherichia coli were collected and analyzed to evaluate a possibility of rapid detection of pathogen. Odor chromatograph showed that S. typhimurium, S. enteritidis, and E. coli had 7,6, and 9 main peaks, respectively. Retention time and intensity of the peaks were distinct for different bacteria species. Principal component analysis (PCA) were also performed to clarify odor differences. Analysis results showed that the odors for uncontaminated growth medium were differently grouped from the odors of contaminated one. The odor from the bacteria growth identified with two principal components, PC 1 and PC2. In PCA figures, odor groups were moved from left to right of PC 1 with elapse of the bacteria growth time. The electronic nose system could detect odors of S. typhimurium, S. enteritidis, E. coli when their concentration were $1.85\times10^6\;cfu/g,\;2.25\times10^6\;cfu/g,\;and\;1.8\times10^5 cfu/g$, respectively.

Simplified Dynamic Modeling of Small-Scaled Rotorcraft (축소형 회전익 항공기의 간략화된 동적 모델링)

  • Lee, Hwan;Lee, Sang-Kee
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.33 no.8
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    • pp.56-64
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    • 2005
  • It is prerequisite that we have to fomulate the nonlinear mathematical modeling to design the guidance and control system of rotorcraft-based unmanned aerial vehicle using a small-scaled commercial helicopter. The small-scaled helicopters are very different from the full-scale helicopters in dynamic behavior such as high rotation speed and high frequency dynamic characteristics. In this paper, the formulation of the mathematical model of the small-scaled helicopter to minimize the complexity is presented by component and source build-up approach. It is linearized at the trim condition of hovering and forward flight and analyzed the flight modes. The results of this approach have general trends but a little difference. To verify this approach, it is necessary to compare this theoretical model with experimental results by system identification using flight test as a next research topic.

Detection and Analysis of the Artificial Underground Explosions in N. Korea using KSRS data. (KSRS 자료를 이용해서 북한의 인공지하폭발의 탐지 및 분석)

  • 김소구;이승규;마상윤;박용철
    • The Journal of Engineering Geology
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    • v.5 no.2
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    • pp.181-192
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    • 1995
  • The discrimination studies between earthquakes and underground nuclear explosions have been carried out by various seismologists(Nuttli and Kim, 1976; Dahiman and Israelson, 1977; Masse, 1981). The discrimination between local microearthquakes and artificial underground explosions(epicentral distance not greater than 400Km), however, has not been actively studied so far in the light of seismological aspects. Futhermore this kind of research has never been performed in Korea even if it is of great importance for IAEA (International Atomic Energy Agency) to clearly analyze the military nuclear power of North Korea at present. This research has been carried out by using some of the artificial underground explosions(about 100 events) have occurred in North Korea for the last six years. The azimuths, apparent incidence angles, epicentral distances and locations are determined using a single station of 3 - component data. The detection, location and identification are performed through the polarization and the bandpass filtering. This technique can be also applied to study the inhomogeneous crustal structure finding the converted waves.

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The Effect of Activated Nitrogen Species for Diffusion Rate during a Plasma Nitriding Process (플라즈마질화에서 발생기 질소와 질화 속도에 관한 연구)

  • Kim, Sang-Gweon;Kim, Sung-Wan;Brand, P.J.
    • Journal of the Korean Society for Heat Treatment
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    • v.23 no.3
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    • pp.150-155
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    • 2010
  • Generally, plasma nitriding process has composed with a nitriding layer within glow discharge region occurred by energy exchange. The dissociations of nitrogen molecules are very difficult to make neutral atoms or ionic nitrogen species via glow discharge area. However, the captured electrons in which a double-folded screen with same potential cathode can stimulate and come out some single atoms or activated ionic species. It was showed an important thing that is called "hat is a dominant component in this nitriding process?" in plasma nitriding process and it can take an effective species for without compound layer. During a plasma nitriding process, it was able to estimate with analyzing and identification by optical emission spectroscopy (OES) study. And then we can make comparative studies on the nitrogen transfer with plasma nitriding and ATONA process using plasma diagnosis and metallurgical observation. From these observations, we can understand role of active species of nitrogen, like N, $N^+$, ${N_2}^+$, ${N_2}^*$ and $NH_x$-radical, in bulk plasma of each process. And the same time, during DC plasma nitriding and other processes, the species of FeN atom or any ionic nitride species were not detected by OES analyzing.

Screening of Quinone Reductase Inducers from Agricultural Byproducts Using Mouse Hepatoma Cell Line (Mouse hepatoma 세포를 이용한 농산부산물로부터 quinone reductase활성물질의 탐색)

  • Kim, Jong-Sang;Nam, Young-Jung;Kim, Joo-Won
    • Korean Journal of Food Science and Technology
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    • v.27 no.6
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    • pp.972-977
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    • 1995
  • The induction of phase II enzymes including quinone reductase [NAD(P)H dehydrogenase(quinone): NAD(P)H : (quinone acceptor) oxidoreductase, EC 1.6.99.2] is a major mechanism of whereby a large group of heterogeneous compounds prevent the toxic, mutagenic, and neoplastic effects of carcinogen. Using murine hepatoma cells(Hepalclc7 cells), quinone reductase(QR) inducers as the possible chemopreventive agents were screened from rice bran, wheat bran, soymilk residue, defatted soybean cake, defatted sesame and perilla residues. The 80% methanol extracts of defatted sesame and perilla residues induced quinone reductase significantly while the others did have little effect on the enzyme induction. Thin layer chromatography of the extracts showed that the fastest moving band(Rf=0.70) in the developing solvent of n-butanol : n-propanol : 2N ammonia(10 : 60 : 30) was responsible for the enzyme induction by the 80% methanol extracts of defatted sesame and perilla residues. Further identification of active component(s) is in progress.

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Function identification of bovine Nramp1 promoter and intron 1

  • Hao, Linlin;Zhang, Libo;Li, Mingtang;Nan, Wang;Liu, Songcai;Zhong, Jifeng
    • Animal cells and systems
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    • v.15 no.3
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    • pp.227-233
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    • 2011
  • The Nramp1/Slc11a1 locus encodes a proton-coupled divalent cation transporter, expressed in late endosomes/lysosomes of macrophages, that constitutes a component of the innate immune response to combat intracellular pathogens and it was shown to play an important role in regulating inherent immunity. The previously identified Z-DNA forming polymorphic repeat(GT)n in the promoter region of the human Nramp1 gene does act as a functional polymorphism influencing gene expression. Research has shown that INF-${\gamma}$, TNF-${\alpha}$, IL-$1{\beta}$ and bacteria LPS increase the level of Nramp1 expression. However, the molecular mechanism for Nramp1 gene regulation is unclear. In this research, bovine Nramp1 5'-flanking region (-1748~+769) was cloned and analyzed by bioinformatics. Then to find the core promoter and the cis-acting elements, deletion analysis of promoter was performed using a set of luciferase reporter gene constructs containing successive deletions of the bovine Nramp1 5'-flanking regions. Promoter activity analysis by the dual luciferase reporter assay system showed that the core promoter of Nramp1 was located at +58~-89 bp. Some positive regulatory elements are located at -89~-205 bp and -278~-1495 bp. And the repressor elements were in region -205~-278 bp, intron1 and -1495~-1748 bp. LPS-responsive regions were located at -1495~-1748 bp and -278~-205 bp. The present study provides an initial effort to explore the molecular mechanism of transcriptional activation of the bovine Nramp1 gene and should facilitate further studies to decode the complex regulatory process and for molecular breeding for disease resistance in bovines.