• Title/Summary/Keyword: Compliance chamber

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Development of the Pulsatile Pump System for a Perfusion Bioreactor (관류형 바이오리액터를 위한 박동 펌프 시스템 개발)

  • Kim, Hak-Jun;Kim, Sun-Hong;Chung, Ho-Yun;Yun, Won-Soo
    • Journal of the Korean Society for Precision Engineering
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    • v.28 no.4
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    • pp.526-533
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    • 2011
  • This research is about the pulsatile pump system utilized in the perfusion bioreactor for the in vitro human tissue culture. A pulsatile pump system which can be applied to the culture of the vascular tissues including blood vessel is developed by using the idea of human heart's blood pumping into organs as followings: culture chamber, a pressurizing device which generates laminar pulsatile flow by controlling the x-sectional area of the culture media delivering tubing, a compliance chamber which supplies the pressuring device with a constant pressure, and a peristaltic pump which circulates the culture media in a circuit ranging from the culture chamber to the compliance chamber. The developed pulsatile pump system shows that a physiology of the human heart's blood pumping including pulsatile pressure waveform of systolic-diastolic pressure is well represented. Not only time domain but also frequency domain characteristics of pulsatile pump system which are necessary for the vascular tissue culture such as pulsatile pressure waveform's shape, the frequency, and the magnitude can be easily generated and manipulated by using the proposed system.

Development of Cardiovascular Simulator with Control of Pulse Pressure for Pulse Wave Study (맥압조절이 가능한 맥파 연구용 심혈관계 시뮬레이터 개발)

  • Lee, Ju-Yeon;Kim, Jeauk U.;Shin, Sang-Hoon
    • Journal of the Institute of Electronics and Information Engineers
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    • v.51 no.10
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    • pp.204-209
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    • 2014
  • The purpose of this study is to produce a simulator that can control a pulse pressure keeping the pulse wave transfer phenomenon. For this, the elastic tube is combined with a compliance chamber for the vessel part. The simulator is comprised of four parts; a pressure generation part with slider-crank mechanism, a vessel part with resistance controller, water reservoirs and a measurement part. The changes of waveform depending on the location of a chamber is examined to determine the position of a chamber. The effects of a chamber on the pulse pressure and the pulse wave transfer phenomenon were investigated. It showed that the simulator which had the chamber in upstream of tube produces pressure wave, being more similar to the clinical waveform than in downstream of tube. Furthermore, with the chamber, the simulator generates a pulse pressure, being more similar to the normal physiological values than without one. The chamber had little effect on the pulse wave velocity.

Stability of the axially compliant fixed scroll in scroll compressors (스크롤 압축기에서 축방향 순응하는 고정부재의 안정성)

  • Kim, H.J.;Lee, W.H.
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.9 no.2
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    • pp.93-103
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    • 1997
  • This study presents a way of improving the stability of fixed scroll in scroll compressors. For the scroll compressor whose fixed scroll is designed to move in the axial direction for the axial compliance, the fixed scroll is under the influence of the overturning moment produced by internal gas forces. Unless the overturning moment is properly compensated by the moments of reaction forces at the suspension of the fixed scroll to the compressor frame, the fixed scroll would exhibit wobbling motion, increasing gas leakage through the gap induced by the wobbling of the fixed scroll between the two scroll members. The conditions on which the wobbling motion can be suppressed have been found analytically; The axial position of the fixed scroll suspension should be made within a certain range. The upper limit of this range is the axial location for the o-rings which are inserted between the fixed scroll and the back pressure chamber to promote sealing for the gas in the back pressure chamber. And the lower limit is mainly determined by the magnitude of the axial sealing force. As long as the axial sealing force is not negative over all crank angles, the lower limit is not above the mid-height of the scroll wrap. Larger axial sealing force lower the lower limit.

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Effects of a Four-week Clothing Program for Improving Vascular Compliance on Heat Tolerance (혈압 관리를 위한 4주간의 착의훈련이 고혈압 전단계자의 내열성에 미치는 영향)

  • Choi, Jeong-Wha;Park, Joon-Hee
    • The Korean Journal of Community Living Science
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    • v.22 no.3
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    • pp.445-454
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    • 2011
  • This study was performed on 5 prehypertensive male participants to investigate the effects of the clothing program for improving the vascular compliance on heat tolerance. The clothing program means the alternate stimulation of the temperature using clothes. The participants wore two different garments with $1.5^{\circ}C$ difference in the temperature inside clothing in a climatic chamber ($18.8{\pm}0.2^{\circ}C$, $38{\pm}3%RH$) alternately for 4 weeks. Heat tolerance tests were conducted in the climatic chamber of $35.2{\pm}0.5^{\circ}C$, $54{\pm}3%RH$ before and after the clothing program. The results were as follows. The $\overline{T}$sk, Tr and heart rate were lower in the post test than in the pre test (p<.01). The whole body and local sweat rates as well as systolic and diastolic blood pressures had reduced the tendencies in the post test. Participants felt less wet and more comfortable in the post test than in the pre test(p<.01). These results showed that the clothing program through the alternate stimulation of the temperature positively affected the improvement of heat tolerance.

A New Method for Enhancement of Right-Left Pump Output Balance in the Totally Implantable Artificial Heart (완전이식형 인공심장의 좌,우 심박출량 균형의 개선에 관한 연구)

  • Choe, Won-U;Kim, Hui-Chan;Kim, Won-Gon;No, Jun-Ryang;Kim, In-Yeong;Min, Byeong-Gu
    • Journal of Biomedical Engineering Research
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    • v.19 no.4
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    • pp.385-391
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    • 1998
  • A new balancing method of atrial pressures balancing for the moving actuator total artificial heart(TAH) without an extra compliance chamber was developed. The asymmetric operation of the pendulous moving actuator have made it possible to compensate the left and right pump output difference by utilizing the interventricular air space as an internal compliance chamber in a pump housing. Furthermore, the balancing performance between left and right pump outputs is increased through the improvement of the flexibility of part of the polyurethane housing. However, the increase of the flexibility of the pump housing causes a little loss of the cardiac output due to the reduction of active filling property. In this paper., a good condition between the balance and pump output performance is evaluated by adjusting the air volume in the interventricular space through a series of in vitro experiments. This new pump was implanted in a sheep weighting 63kg, and it survived for 3 days and the average cardiac output during postoperative days was about 4.2 L/mim with the atrial pressures under 15 mmHg.

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A Study on the Design of Back Pressure for Automotive Scroll Compressor

  • Koo, In-Hwe;Lee, Geon-Ho
    • International Journal of Air-Conditioning and Refrigeration
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    • v.17 no.1
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    • pp.1-6
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    • 2009
  • The optimum design of back pressure chamber is one of the most important factors in designing scroll compressors because it has a great influence on the efficiency and other design parameters. The design process can be divided into 2 parts. One is obtaining the optimum pressure of the chamber and keeping it in constant value. The other is finding out the minimum inflow rate of medium with which back pressure chamber is filled. In this study we are focused on the first step. At first we added a simple structure that can change back pressure without reassembling compressor. It makes possible to obtaining optimum back pressure. Then we designed an equipment that the back pressure control valve assembly could be independently tested with. Spring was redesigned to decrease stiffness variation. Also sealing mechanism of back pressure control valve was improved to more effective way. As a result, it was verified that in a real mode test back pressure variation could be retained in 2.3% with discharge pressure and operating frequency varied. In addition the integrated structure of back pressure control valve is expected to contribute to effective manufacturing process.

A Study On the Improvement of Atrial Pressures Balancing Performance of Total Artificial Heart (완전이식형 인공심장의 심방압 균형성능의 개선에 관한 연구)

  • Choi, Won-Woo;Park, Seong-Keun;Jo, Yung-Ho;Choi, Jae-Soon;Lee, Dong-Joon;Kim, Hee-Chan;Min, Byoung-Goo
    • Proceedings of the KOSOMBE Conference
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    • v.1995 no.11
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    • pp.216-218
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    • 1995
  • A new atrial pressures balancing method for moving actuator total artificial heart(TAH) without an extra compliance chamber is developed. The structural characteristics of the pendulous moving actuator have made it possible to compensate the left and right pump output difference by utilizing the interventricular air space as an internal compliance chamber in a pump housing. Furthermore, the balancing performance is increased through the improvement of the flexibility of part of the polyurathane housing. However, the increase of the flexibility of the housing causes a little loss of the cardiac output due to the reduction of active filling performance. In this paper, a good condition between the balance and pump output performance is evaluated by adjusting the air volume in the interventricular space through a series of in vitro experiment.

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Analysis of the Relation Between Micro-Speaker with the Back Holes and the Ducted Speaker-System (후면기공을 갖는 마이크로스피커와 덕트형 스피커시스템사이의 연관성 해석)

  • Rhee, Esther;Oh, Sei-Jin
    • The Journal of the Acoustical Society of Korea
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    • v.26 no.3
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    • pp.115-122
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    • 2007
  • In this study, the property and the structure of micro-speaker had been firstly shown to be treated as a ducted speaker-system, which was consisted of the unit and the ducted enclosure. With the decrease of total hole area. the resonance frequency of micro-speaker was decreased due to increasing the stiffness or reducing the compliance. The behavior of resonance frequency relative to the total hole area was exactly agreed with that of the square root of compliance. With decreasing the total hole area. the effective chamber volume was increased, but the reference sound pressure level was exponentially reduced in the low and middle frequency range.

Effect of Number and Condition of Reflection Site on Pulse Wave (반사 지점의 개수와 조건이 맥파에 미치는 영향)

  • Lee, Min-Woo;Jang, Min;Shin, Sang-Hoon
    • Journal of Biomedical Engineering Research
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    • v.41 no.1
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    • pp.8-13
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    • 2020
  • To develop cardiovascular simulator capable of implementing pulse waves similar to the human body, accurate information about reflection wave is required. However, the conclusion is still not clear and various discussions are underway. In this study, the pulse wave velocity of the tube used in the experiment was first determined by measuring the pressure waves at two points in a single tube system with the experimental device to implement the pulse wave transmission of blood vessels, and the superposition time and characteristics of the reflection wave were confirmed. After that, an air chamber was set at the reflection site, and the effect of the change of air volume on the reflection wave was investigated. Finally, the effect of the number of branches connected to a single tube on the reflection wave was investigated. The superposition time of the reflection wave can be controlled by the air volume of the air chamber, and the magnitude of the reflection wave is influenced by the number of reflection sites that generate the reflection wave. The results of this study may be of practical assistance to simulator researchers who want to implement pulse wave similar to clinical data. It is expected that the more results similar to clinical are provided, the greater the scope of the simulator's contribution to clinical cardiovascular research.

On the Stability of the Axially Compliant Fixed Scroll Member in Scroll Compressors

  • Hyun Jin Kim
    • International Journal of Air-Conditioning and Refrigeration
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    • v.10 no.1
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    • pp.40-49
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    • 2002
  • Floating fixed scroll adopted for tip sealing enhancement in a scroll compressor is always under the influence of tipping moment produced by internal gas forces. Unless the tipping moment is property compensated by some restoring moment, the fired scroll would suffer tipping movement, degrading the compressor performance. The condition on which the tipping movement of the fixed scroll can be suppressed has been investigated analytically. For no tipping movement, the floating fixed scroll should be suspended on the main frame at proper level. The upper limit of the stable suspension is the axial location of the o-rings adopted for a back pressure chamber sealing on the rear side of the fixed scroll, and the lower limit is the mid-height of the scroll wrap.