• 대한기계학회논문집B
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• 제35권11호
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• pp.1163-1168
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• 2011

압축착화 방식의 디젤엔진은 스파크점화 방식의 가솔린 엔진에 비하여 열효율이 높아 연비가 향상되고 그 결과 $CO_2$ 저감효과도 높다. 또한 디젤엔진은 점화계통 장치의 불필요 등 기존 엔진의 개조비용이 적어 세탄가가 높은 바이오연료의 적용엔진으로서 적합한 장점이 있다. 따라서 본 연구에서는 식물성 자트로파유, 대두유 2종의 바이오연료와 경유연료의 분무특성을 비교 분석하였다. 실험변수로서는 분사압력과 자트로파 연료의 경우는 혼합비율(BD3, BD5, BD20)을 달리하였다. 분사압력은 500bar, 1000bar, 1500bar 및 1600bar로 설정하고 분사기간은 500ms로 동일하게 하였다. 본 연구의 결과로서, 사용한 바이오디젤 연료의 종류 및 분사압력 변화에 대한 분무거동특성(분무각)의 변화는 뚜렷하지 않으나, 고압분사의 경우가 분무각이 약간 감소하는 결과를 얻을 수 있었다.

• Journal of Korean Biological Nursing Science
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• 제23권3호
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• pp.199-207
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• 2021

Purpose: The purpose of this study was to investigate effects of NXP031, an inhibitor of oxidation by specifically binding to the complex of DNA aptamer/vitamin C, on dopaminergic neurons loss and the reaction of microglia in an animal model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced subchronic Parkinson's disease (PD). Methods: A subchronic PD mouse model was induced via an intraperitoneal (IP) injection of MPTP 30 mg/kg per day for five days. NXP031 (vitamin C/aptamer at 200 mg/4 mg/kg) and vitamin C at 200 mg/kg were administered via IP injections at one hour after performing MPTP injection. This process was performed for five days. Motor function was then evaluated with pole and rotarod tests, after which an immunohistochemical analysis was performed. Results: NXP031 administration after MPTP injection significantly improved motor functions (via both pole and rotarod tests) compared to the control (MPTP injection only) (p<.001). NXP031 alleviated the loss of dopaminergic neurons in the substantia nigra (SN) and striatum caused by MPTP injection. It was found to have a neuroprotective effect by reducing microglia activity. Conclusion: NXP031 can improve impaired motor function, showing neuroprotective effects on dopaminergic neurons in the SN and striatum of MPTP-induced subchronic Parkinson's disease mouse model. Results of this study suggest that NXP031 has potential in future treatments for PD and interventions for nerve recovery.

• 환경위생공학
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• 제18권1호
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• pp.23-29
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• 2003

The effect of ozone oxidation on bio-degradability of leachate was studied. Ozone oxidation process was used as pre-treatment process to enhance performance of biological process in treating landfill leachate. Optimum ozone injection rate and contact time in this experiment was $160{\;}mg{\;}O_/{\ell}{\cdot}hr$ and 45 minutes, respectively. Bio-degradability was enhanced 5.08% by ozone oxidation. The ratio of ozone demand/DOC concentration was $0.049~0.091{\;}mg{\;}O_3/mg{\;}DOC$. The increase of bio-degradability depending on ozone injection rate(D) and contact time(T) can be expressed as follows ; The rate of bio-degradation of DOC was increased proportionally with the increase of ozone injection rate and contact time irrespective of landfill site age. The increase of bio-degradability by ozone addition was not satisfactory. It is hard to expect significant increase in bio-degradability by ozone treatment only. Thus, it is evaluated that ozone oxidation can not increase biodegradability significantly in concentrated wastewater composed of complex organic compound such as leachate.

• 한국유체기계학회 논문집
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• 제6권3호
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• pp.21-27
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• 2003

Dispersion of coolant jets in a film cooling flow field is the result of a highly complex interaction between the film cooling jets and the mainstream. In order to investigate the effect of blowing ratios on the film cooling of a turbine blade, cylindrical body model is used. Mainstream Reynolds number based on the cylinder diameter is $7.1{\times}10^4$. The effects of coolant flow rates are studied for blowing ratios of 0.7, 1.0, 1.3 and 1.7, respectively. The temperature distribution of the cylindrical model surface is visualized with infrared thermography (IRT). Results show that the film cooling performance could be significantly improved by the shaped injection holes. For higher blowing ratio, the spanwise-diffused injection holes are better due to the lower momentum flux away from the wall plane at the hole exit.

• Design & Manufacturing
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• 제12권3호
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• pp.36-41
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• 2018

Metal 3D printing is very useful for making the injection molds containing complex conformal cooling channels. The most important issue of the 3D printed molds is cost and life cycle. However, powder bed fusion (PBF) methods are vulnerable to fatigue loading because of the presence of pores and rough surfaces. In the present study, the fatigue test was performed to obtain fatigue analysis input data for predicting the durability of a 3D printed injection mold core. The metal 3D printer used to manufacture the specimen was OPM250L from Sodick, and the metal powder material was maraging steel. The ultrasonic fatigue testing method was adopted for the fatigue test. A key advantage of the ultrasonic fatigue method is that $10^8{\sim}10^9$ long cycle test data or more could be obtained within a relatively short period. Based on the results of the experiment, the effect of heat treatment was negligible. However, there was an apparent difference in durability depending on the presence or absence of the surface treatment.

• Environmental Analysis Health and Toxicology
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• 제14권1_2호
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• pp.13-19
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• 1999

Cisplatin is an inorganic complex formed by a central atom of platinum surrounded by chlorine and ammonia atoms in the cis position in the horizontal plane, Cisplatin is one of the most effective anticancer drug, widely used against various tumor such as testicular tumor, brain tumor, ovary tumor, bladder carcinoma, colon cancer etc. However its clinical use has been limited by nephrotoxicity, ototoxicity , gastrointestinal disturbances, myeloscrppression and allergic reactions. In these toxicities, dose related and cumulative nephrotoxicity is the major dose limit factor. So, to evaluate the protective effect of aspalactone on cisplatin nephrotoxicity in rats, both compounds were given intraperitoneally, Protective effects of aspalactone against nephrotoxicity of cisplatin were observed when aspalactone was administered to rats 1hr beforecisplatin injection. Hepatotoxicity induced by combination treatment of cisplatin and aspalactone was not observed. The present results indicate that aspalactone may provide protection against cisplatin nephrotoxicity, when it is given 1hr before cisplatin injection.

• 한국분말재료학회지
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• 제21권1호
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• pp.1-6
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• 2014

Medical technologies are gaining in importance because of scientific and technical progress in medicine and the increasing average lifetime of people. This has opened up a huge market for medical devices, where complex-shaped metallic parts made from biocompatible materials are in great demand. Today many of these components are already being manufactured by powder metallurgy technologies. This includes mass production of standard products and also customized components. In this paper some aspects related to metal injection molding of Ti and its alloys as well as modifications of microstructure and surface finish were discussed. The process chain of additive manufacturing (AM) was described and the current state of the art of AM processes like Selective Laser Melting and electron beam melting for medical applications was presented.

• 한국분말재료학회지
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• 제20권5호
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• pp.323-331
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• 2013

In this paper, two kinds of advanced powder processing techniques Metal Injection Molding (MIM) and Direct Laser Forming (DLF) are introduced to fabricate complex shaped Ti alloy parts which are widely used for medical and aerospace applications. The MIM process is used to strengthen Ti-6Al-4V alloy compacts by addition of fine Mo, Fe or Cr powders. Enhanced tensile strength of 1030 MPa with 15.1% elongation was obtained by an addition of 4 mass%Cr because of the microstructural modification and also the solution strengthening in beta phase. However, their fatigue strength was lower compared to wrought materials, but was improved by HIP. Subsequently, the effect of feeding layer height (FLH) on the characteristics of the DLF compacts was investigated. In the case of 100 ${\mu}m$ FLH, surface roughness was improved and nearly full density (99.8%) was obtained. Also, tensile strength of 1080 MPa was obtained, which is higher than the ASTM value.

• 전력전자학회논문지
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• 제8권2호
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• pp.199-210
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• 2003

본 논문에서는 계통연계형 태양광발전시스템의 고립운전방지를 위한 새로운 고리운전 검출기법을 연구한다. 이를 위하여 계통연계형 태양광발전시스템 및 고립운전시의 특성에 대하여 기술하였다. 또한 고립운전의 검출특성을 향상시키기 위한 새로운 검출기법을 제시하고 해석하였으며 검출시험을 위한 부하조건 선정을 위한 부하임피던스 곡선을 해석적으로 유포하였다 ACSL 시뮬레이션 및 실험을 통하여 제시한 고립운전 검출기법 및 해석결과를 검증하였다.

• 혜화의학회지
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• 제14권2호
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• pp.153-158
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• 2005

Objective : We performed this study to understand the trend of recent medical treatment on chronic prostatitis. Methods : We analyzed 20 manuscripts contributed to the Chinese medical journals from 1998 to 2004 that presenting report of recent medical treatment on chronic prostatitis. Results : The results are summarized as follows 1. In clinical cases, we investigate the cause of chronic prostitis was 'ha cho sup yol' 'ki wool' and 'hyul er'. also it combined complex causes. 2. Deep stimulation acu-therapy near prostate was more effective than other acu therapy. 3. External medical treatment was very efficient than other therapy that was rectal injection therapy, fumigation therapy etc. Conclusion : We conclusion that Rectal Injection therapy was clinical effect on chronic prostatitis.