• BMB Reports
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• 제31권4호
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• pp.307-327
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• 1998

Cytochrome c peroxidase (CcP) is a yeast mitochondrial enzyme which catalyzes the reduction of hydrogen peroxide to water using two equivalents of ferrocytochrome c. The CcP/cytochrome c system has many features which make it a very useful model for detailed investigation of heme protein structure/function relationships including activation of hydrogen peroxide, protein-protein interactions, and long-range electron transfer. Both CcP and cytochrome c are single heme, single subunit proteins of modest size. High-resolution crystallographic structures of both proteins, of one-to-one complexes of the two proteins, and a number of active-site mutants are available. Site-directed mutagenesis studies indicate that the distal histidine in CcP is primarily responsible for rapid utilization of hydrogen peroxide implying significantly different properties of the distal histidine in the peroxidases compared to the globins. CcP and cytochrome c bind to form a dynamic one-to-one complex. The binding is largely electrostatic in nature with a small, unfavorable enthalpy of binding and a large positive entropy change upon complex formation. The cytochrome c-binding site on CcP has been mapped in solution by measuring the binding affinities between cytochrome c and a number of CcP surface mutations. The binding site for cytochrome c in solution is consistent with the crystallographic structure of the one-to-one complex. Evidence for the involvement of a second, low-affinity cytochrome c-binding site on CcP in long-range electron transfer between the two proteins is reviewed.

• KIEAE Journal
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• 제6권3호
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• pp.27-34
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• 2006

The recent emphasis on ecological urban development has led to the need to maintain a hydrologic cycle in urban areas. As such, this study proposes decentralized rainwater management, a concept of onsite rainwater management that involves the utilization, infiltration, detention, and retention of rainwater. The main objective of this research is to estimate the proportion of decentralized rainwater management that is needed. From the research that was conducted in this study, it was found that the total runoff quantity increases by 10-20% after district lands are developed, when the probable rate of precipitation every 10 years is within this range. Thus, the runoff rate can be reduced by 10~20% of the total runoff quantity through decentralization. On the other hand, in the scale of housing complex development, the total runoff quantity increases by as much as 10~40% due to the changes in the rate of the impervious surface area. If 10-40% of the total runoff quantity was processed through decentralized rainwater management, the rate of infiltration, detention, retention, and runoff in precipitation prior to development could be recovered.

• KIEAE Journal
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• 제5권3호
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• pp.17-24
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• 2005

Until today, rainwater management was processed without disposing the peak discharge, which was due to rainfall, to provide stability against flood damage. In this process, the natural hydrologic cycle changed quickly, and because of this, some problems that could harm human beings and the environment arose. These problems need to be addressed accordingly. One of the proposals was to carry out decentralized rainwater management through a natural hydrologic cycle on site, including utilization, infiltration, detention, and retention of rainwater. This study aims to set the direction of applicable decentralized rainwater management to housing complex in Korea. Therefore, spacial properties in urban housing complexes were analysed such as the impervious area-to-land ratio, the green area-to-land ratio, artificial land-to-land ratio etc. As the result of this study, when a housing complex was small and developed by reconstruction, the impervious area, artificial land, the green area in the artificial land-to-land ratio were high. So, direction of decentralized rainwater management of these housing complexes is available to utilize and detain rainwater. On the other hand, those of big housing complexes in land development district were low relatively. So, direction of decentralized rainwater management of these housing complexes is available to infiltrate and evaporate rainwater.

• 한국의류학회지
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• 제44권5호
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• pp.950-968
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• 2020

This study derives the modern characteristics of the paisley ornament through an analysis of the paisley ornament shown in fashion since the 2010s based on a theoretical review of the paisley ornament used in Kashmir India shawls for artistic inspiration in the fashion-textile field. It classified the paisley ornament in fashion since the 2010s into types of 'basic structure of body and coif', 'abnormal paisley ornament shapes', 'complex structure of paisley ornament', 'complex structure with other motif', 'a pair of symmetrical reflection motif', 'regular of repetitive arrangement', 'complex arrangement of irregularity and regularity' and 'free arrangement of irregularity'. A comparative analysis with the historical paisley ornament shows that paisley ornaments have contemporary characteristics like 'Bisector structure of centerline in criterion of the body', 'Composite structure of extended 1-repeat', and 'Free structure of engineered placement'. A modern design was inspired by the historical art forms; however, it was used in free utilization of motifs and patterns in terms of size, direction, proportion and space. These were the expression of a design identity that originated from the aesthetic ability and career of a designer as well as the technology of computer programs for the improvements in time and cost efficiency.

• 대한안전경영과학회지
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• 제24권1호
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• pp.73-80
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• 2022

The purpose of this study is to present the direction of the plan to transform the residential complex into a space that can provide an open residential environment that can lead to social communication and exchange without being closed to the urban residential environment, especially in the apartment complex environment, which is becoming more dense. As a result of the Openness analysis of the 'Codan Shinonome Canal Court', the overall accessibility was good in terms of space utilization, and the openness was low in terms of the spatial composition, which is a physical environment due to the dense block type. When looking at the overall openness of the Codan Sinonome complex in terms of analysis by block, the corrected openness index (C.O.I) for all six blocks was 0.245, the corrected accessibility index (C.A.I) was 1.447 and the openness composite index (O.C.I) was assessed at 1.692. This was due to the formation of high-density block-type urban dwellings and the introduction of S-shaped streets and the layout of low-rise urban support facilities and commercial facilities. The Codan Sinonome Canal Court, which is considered an "open city residence," quantitatively confirmed that it embodies macro-space structure and human-scale space environment even in high-precision environments.

• Nuclear Engineering and Technology
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• 제53권2호
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• pp.393-398
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• 2021

Current risk assessment of Spent Nuclear Fuel (SNF) transportation has the problem of the incomplete risk factors consideration and the general particle diffusion model utilization. In this paper, the accident frequency calculation and the detailed simulation of the accident consequences are coupled by the integrated risk assessment method. The "man-machine-environment" three-dimensional comprehensive risk indicator system is established and quantified to characterize the frequency of the transportation accidents. Consideration of vegetation, building and turbulence effect, the standard k-ε model is updated to simulate radioactive consequence of leakage accidents under complex terrain. The developed method is applied to assess the risk of the leakage accident in the scene of the typical domestic SNF Road Transportation (SNFRT). The critical risk factors and their impacts on the dispersion of the radionuclide are obtained.

• 한국식품과학회지
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• 제35권2호
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• pp.266-271
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• 2003

CD의 inclusion complex 형성능을 이용하여 대표적인 polyphenol계 천연 항산화 물질인 quercertin 및 catechin을 안정화시키는 분자 캡슐화 기술을 연구하였다. 먼저 ${\alpha}-,\;{\beta}-$, 그리고 ${\gamma}-CD$의 quercetin 및 catechin의 포접능을 비교하였다. Quercetin/catechin-CD inclusion complex 형성을 DSC thermogram을 이용하여 확인하였다. 또한 ${\beta}-CD$와의 포접에 따른 저용해성 quercetin과 catechin의 물에 대한 용해도의 변화를 관찰한 결과 inclusion complex 형성 시 용해도가 증가하는 것을 관찰할 수 있었다. Inclusion complex의 온도 및 pH에 대한 안정성을 검토한 결과 inclusion complex가 원래의 물질보다 높은 항산화능을 유지하였으며 특히 catechin의 안정성이 크게 향상되었다. Catechin-CD inclusion complex의 식품보존제로서의 적합성을 지방산인 linoleic acid를 시료로 검토하기 위하여 저장 중 과산화물가의 변화를 측정한 결과 포접된 catechin이 보다 높은 항산화능을 보였다. 이와 같은 용해도 및 항산화능의 증가로 볼 때 quercetin/catechin-CD inclusion complex는 신선식품의 보존제로 효과적으로 활용될 수 있는 것으로 판단된다.

• 통상정보연구
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• 제16권5호
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• pp.249-273
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• 2014

본 연구는 우리나라의 무역업체를 대상으로 실시한 설문조사를 통해 지금까지 추진해 온 FTA에 대한 우리 무역업계의 평가를 살펴보고 활용에 있어 애로요인을 파악함으로써 지원정책에 대한 시사점과 대응방안을 모색하고자 하였다. 설문조사에 따르면 대부분의 무역업체는 FTA를 활용해 본 경험이 있었으며, FTA를 활용한 무역업체의 대부분은 FTA가 기업경영 및 수출입 확대에 도움이 되었다고 평가하였다. 그러나 응답기업 중에는 FTA를 활용해 본 경험이 없다고 응답한 기업도 상당수 있었으며, 활용한 경험이 있는 기업들도 복잡한 원산지규정과 실질적 정보부족 등으로 FTA를 활용하는데 어려움이 있음을 밝히고 있다. 따라서 FTA의 활용도를 높이기 위한 노력의 필요성이 제기되었고, 지원정책 또한 업계가 필요로 하는 실질적인 정책으로의 전환이 요구되었다. 또한 무역업계는 향후 체결될 FTA에 대해 가능한 동아시아 거대 경제권과의 FTA 체결을 선호하였으며, FTA가 기업경영에 실질적 도움이 되는 방향에서 추진되기를 희망하였다.

• 보건행정학회지
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• 제17권2호
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• pp.33-51
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• 2007

The disabled population is a vulnerable group, having very complex medical conditions, but little is known about differences in the level of access by type of disability. This study was performed to investigate the differences of health care utilization by the type of disability. The database was constructed from registry of the disabled and health insurance and medical aid claims data submitted to the Korea Health Insurance Cooperation during in the year 2003. The disability classified three groups according to the Disabled Welfare Act; physically disability with external dysfunction, physically disability with organic disease, and mentally disability. There were huge differences in health care utilization by the type of disability. For the inpatient care, those with a mental disability were more likely to utilize health care services in terms of average visit number of medical facilities and visit days per case, but the treatment amount per case was the highest in physically disabled with organic disease. For the outpatient care, those who the physically disabled with organic disease were more likely to utilize health care services in terms of average visit number of medical facilities, treatment amount per case, and the treatment days per case. Also, those who physically disabled with organic disease were more likely to utilize general hospital for both inpatient and outpatient care, and spent more out-of-pocket expenditure. As the number of persons with disabilities rises, the need to consider new approaches to protecting their health grows increasingly. Especially, Korean health care system should be refined to be more responsive to the needs of the type of disability.

• 헤리티지:역사와 과학
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• 제51권2호
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• pp.58-77
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• 2018

남원지역은 대가야와 백제라는 커다란 세력이 부딪치기도 하고 교류하기도 하면서 형성된 문화가 복합적인 양상을 드러내는 곳이다. 즉, 남강의 상류에 해당하는 운봉 아영고원 일대에는 대가야계 고총이 집중적으로 조영되지만 소가야의 흔적이 보이고 백제의 위세품이 부장되며, 섬진강유역의 남원시 서부 일대에는 5세기 후반 이후 일부 가야계 문물이 보이고 분구묘 계통의 고분이 축조되면서 복합적인 양상을 보이지만 6세기 이후 백제화 과정이 뚜렷해진다. 그런데 이 지역의 성장 과정을 대가야와 백제만의 시각으로 보아서는 실체에 접근하기 어렵다. 최근 토착세력의 분구묘도 조사되고 있으므로 앞으로는 토착 세력의 성장 기반, 백제 왕권과 대가야세력과의 관계를 이용한 현지 세력의 성장 과정에 초점을 맞춰 조사하고 분석할 필요도 있다. 이처럼 고분은 고대사회의 남원을 파악하는 데 중요한 실마리이다. 고분을 통해 지역의 정체성을 확립하고 적절히 보존 및 활용하기 위해서는 우선 현상 파악을 위한 기초조사가 이루어져야 한다. 그리고 고분의 성격을 파악하기 위한 조사와 연구가 필요하다. 이를 바탕으로 지역민에게 고분군의 중요성을 알려 보존 및 활용 활동에 함께 참여하도록 해야 한다. 보존 및 활용은 가장 상위의 복합형을 지향해야 하겠지만 제대로 기초조사조차 이루어지지 않은 현상에 기초하여 단계적으로 개선해 나가야 할 것이다. 이를 위해서는 남원시에 이와 관련된 조직과 예산이 항시적으로 배분되어야 한다.