• Transactions on Electrical and Electronic Materials
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• 제16권2호
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• pp.65-69
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• 2015

Low level laser therapy (LLLT) has facilitated an improvement in acupuncture treatment. In this study, we stimulated Shaochong (HT9), Dadun (LR1), Shaohai (HT3), and Yingu (KI10) acupoints with pulsed laser diodes 532 nm [green laser] and 658 nm [red laser] in rats with induced middle cerebral artery occlusion(MCAO). The animals were divided into 6 groups: intact control; MCAO control without LLLT; LLLT with red laser at HT9·LR1 and HT3·KI10 (RR); LLLT with green laser at HT9·LR1 and HT3·KI10 (GG); LLLT with green laser at HT9·LR1 and red laser at HT3·KI10 (GR); and LLLT with red laser at HT9·LR1 and green laser at HT3·KI10 (RG). We evaluated the immunohistochemical changes in the hippocampal CA1 region, and complete blood count changes. Compared to the MCAO control group, the RG group showed a significant decrease in Bax and cytochrome c levels in the hippocampus, and a significant increase in hemoglobin level, hematocrit, total white blood cell, neutrophil, lymphocyte, monocyte, and erythrocyte counts.

• 산업경영시스템학회지
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• 제39권3호
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• pp.56-63
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• 2016

For air express service providers offering various express delivery services such as overnight delivery and next-business day delivery services, establishing quickly cargo loading plans is one of important issues owing to the characteristics of air express business, i.e., a short amount of time is available to complete all cargo loading operations before flight departure after receiving air express containers, pallets and bulks. On the other hand, one of major concerns in the air cargo loading planning is to make a plan that insures the stability of an aircraft to avoid take-off, flight, and landing accidents. To this end, this paper considers an air cargo loading planning problem, which is the problem of determining locations in the aircraft cargo space where air containers, pallets and bulks to be loaded while insuring the aircraft stability, motivated from DHL and Air Hong Kong. The objective of the problem is to maximize the total revenue gained from loading air express containers, pallets and bulks. To solve the problem, this paper suggests a simulated annealing algorithm to overcome impracticality of the integer programming model developed by a previous study requiring excessive computation time. The results of computational experiments show that the heuristic algorithm is a viable tool for establishing express cargo loading plans as giving robust and good solutions in a short amount of computation time. Scenario analyses are performed to investigate the effect of the current activities of air express carriers on the revenue change and to draw practical implications for air express service providers.

• 한국발생생물학회:학술대회논문집
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• 한국발생생물학회 2003년도 제3회 국제심포지움 및 학술대회
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• pp.24-25
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• 2003

The zebrafish (Danio rerio) is now the pre-eminent vertebrate model system for clarification of the roles of specific genes and signaling pathways in development. I will talk about positional cloning of two developmental mutants in zebrafish. The first mutant is headless: The vertebrate organizer can induce a complete body axis when transplanted to the ventral side of a host embryo by virtue of its distinct head and trunk inducing properties. Wingless/Wntantagonists secreted by the organizer have been identified as head inducers. Their ectopic expression can promote head formation, whereas ectopic activation of Wnt signalling during early gastrulation blocks head formation. These observations suggest that the ability of head inducers to inhibit Wntsignalling during formation of anterior structures is what distinguishes them from trunk inducers that permit the operation of posteriorizing Wnt signals. I describe the zebrafish headless (hdl) mutant and show that its severe head defects are due to a mutation in T-cell factor-3 (Tcf3), a member of the Tcf/Lef family. Loss of Tcf3 function in the hdl mutant reveals that hdl represses Wnt target genes. I provide genetic evidence that a component of the Wntsignalling pathway is essential in vertebrate head formation and patterning. Second mutant is mind bomb: Lateral inhibition, mediated by Notch signaling, leads to the selection of cells that are permitted to become neurons within domains defined by proneuralgene expression. Reduced lateral inhibition in zebrafish mib mutant embryos permits too many neural progenitors to differentiate as neurons. Positional cloning of mib revealed that it is a gene in the Notch pathway that encodes a RING ubiquitin ligase. Mib interacts with the intracellular domain of Delta to promote its ubiquitylation and internalization. Cell transplantation studies suggest that mib function is essential in the signaling cell for efficient activation of Notch in neighboring cells. (중략)

• 한국산업정보학회논문지
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• 제19권1호
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• pp.53-60
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• 2014

IEEE 802.15.4의 물리계층은 저속, 저전력, 저가격 기반의 LR-WPAN(Low-Rate Wireless Personal Area Network)의 물리계층으로 세계적으로 가장 많이 사용되고 있다. IEEE 802.15.4에 대한 기존의 많은 이론 연구들은 저전력 무선네트워크 환경에서의 에너지효율성, 전송처리율, 전송신뢰성에 대한 거시적 이해와 안목을 제공하는 중요한 결과들을 산출하고 있다. 이 논문에서는 이러한 이론연구에 실환경 요소를 보완하기 위해 MAC(Medium Access Control) 소프트웨어 구조부터 실제 네트워크 기반 성능분석에 이르는 실험연구를 수행한다. 연구에서는 수직분할 모델의 네트워킹 스택의 MAC 계층 기능으로 IEEE 802.15.4 MAC 스택을 구현하고 이를 네트워킹 스택에 통합하여 시험 분석을 수행한다. 이 연구에서 도출한 네트워크 소프트웨어 모델과 실험결과는 향후 IEEE 802.15.4 MAC 소프트웨어의 구현과 실용적인 네트워크 스택 환경에서의 성능에 참고자료로 활용될 수 있다.

• 산경연구논집
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• 제10권12호
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• pp.35-42
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• 2019

Purpose : This study examines The impact of human resource investment in internal control on stock price crash risk. Effective internal control ensures that information provided is complete and accurate, financial statements are reliable. By overseeing management, internal control systems can reduce agency costs between management and outside parties. In Korea, firms have to disclose information about internal control systems. The working experience of human resources in internal control systems is also provided for interested parties. If a firm hires more experienced internal control personnel, it can better facilitate the disclosure of information. Prior studies reported that information asymmetry between managers and investors increases future stock price crash risk. Therefore, the longer working experience internal control personnel have, the lower probability stock crashes have. Research design, data and methodology : This study analyzed the association between the working experience of internal control personnel and crash risk using regression analysis on KOSPI listed companies for fiscal years 2016 through 2017. The sample consists of 1,034 firm-years of non-financial firms whose fiscal year end on December 31. Career spanning data of internal control personnel was collected from internal control reports. The professionalism(IC_EXP) was measured as the logarithm of the average working experience of internal control personnel in months. Negative conditional skewness(NSKEW) and down-to-up volatility (DUVOL) are used to measure firm-specific crash risk. Both measures are based on firm-specific weekly returns derived from the expanded market model. Results : We find that work experience in internal control environment is negatively related to stock price crashes. Specifically, skewness(NSKEW) and volatility (DUVOL) are reduced when firms have longer tenure of human resources in internal control division. The results imply that firms with experienced internal control personnel are less likely to experience stock price crashes. Conclusions : Stock price crashes occur when investors realize that stock prices have been inflated due to information asymmetry. There is a learning effect when internal control processes are done repetitively. Thus, firms with more experienced internal control personnel could manage their internal control more effectively. The results of this study suggest that firms could decrease information asymmetry by investing in human resources for their internal control system.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1994년도 추계학술대회
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• pp.71-74
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• 1994

In cementless total hip arthroplasty(THA), an initial stability of the femoral component is mandatory to achieve bony ingrowth and secondary long term fixation. Bone ingrowth depends strongly on relative micromotion and stress distributions at the interface. Primary stability of the femoral component can be obtained by minimizing the magnitude of relative micromotions at bone-prosthesis interface, Hence an accurate evaluation of interface behavior and stress/strain fields in the bone implant system may be relevant for better understanding of clinical situations and improving THA design. However, complete evaluation of load transfer in the bone remains difficult to assess experimentally, Hence, recently finite element method (FEM) was introduced in orthopaedic research field to fill the gap due to its unique capacity to evaluate stress in structure of complex shape, loading and material behavior. The authors developed the 3-dimensional numerical finite element model which is composed of totally 1179 elements off and 8 node blick. We also analyzed the micromotions at the bone-stem interface and mechanical behavior of existing bone prosthesis for a loading condition simulating the single leg stance. The result indicates that the values of relative motion for this well fit Multilock stem were $150{\mu}m$ in maximum, $82{\mu}m$ in minimum, and the largest relative motion developed in medial region of proximal femur with anterior-posterior direction. The proximal region of the bone was much larger in motion than the distal region and the stress pattern shows high stress concentration on the cortex near the tip of the stem. These findings indicates that the loading in the proximal femoral bone in the early postoperative situation can produce micromotions on the interface and clinically cementless TEA patient should not be allowed weight bearing strictly early in the postoperative period.

• 한국농공학회지
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• 제38권5호
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• pp.74-84
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• 1996

Dynamic loading of structures often causes excursions of stresses well into the inelastic range and the influence of geometric changes on the dynamic response is also significant in many cases. Therefore, both material and geometric nonlinearity effects should be considered in case that a dynamic load acts on the structure. For developing a program to analyze the dynamic response of an axisymmetric shell in this study, the material nonlinearity effect on the dynamic response was formulated by the elasto-viscoplastic model highly corresponding to the real behavior of the material. Also, the geometrically nonlinear behavior is taken into account using a total Lagrangian coordinate system, and the equilibrium equation of motion was numerically solved by a central difference scheme. A complete finite element program has been developed and the results obtained by it are compared with those in the references 1 and 2. The results are in good agreement with each other. As a case study of its application, the developed program was applied to a dynamic response analysis of a nuclear reinforced concrete containment structure. The results obtained from the' numerical examples are summarized as follows : 1. The dynamic magnification factor of the displacement and the stress were unrelated with the concrete strength. 2. As shown by the results that the displacement dynamic magnification factor were form 1.7 to 2.3 and the stress dynamic magnification factor from 1.8 to 2.5, the dynamic magnification factor of stress were larger than that of displacement. 3. The dynamic magnification factor of stress on the exterior surface was larger than that on the interior surface of the structure.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제3권8호
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• pp.309-314
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• 2014

물체의 360도 방향에서 다수의 RGB-D(RGB-Depth) 카메라를 이용하여 깊이영상을 획득하고 3차원 모델을 생성하기 위해서는 RGB-D 카메라 간의 3차원 변환관계를 구하여야 한다. 본 논문에서는 구형 물체를 이용하여 4대의 RGB-D 카메라 사이의 변환관계를 간편하게 구할 수 있는 시점보정(view calibration) 방법을 제안한다. 기존의 시점보정 방법들은 평면 형태의 체크보드나 코드화된 패턴을 가진 3차원 물체를 주로 사용함으로써 패턴의 특징이나 코드를 추출하고 정합하는 작업에 상당한 시간이 걸린다. 본 논문에서는 구형 물체의 깊이영상과 사진영상을 동시에 사용하여 간편하게 시점을 보정할 수 있는 방법을 제안한다. 우선 하나의 구를 모델링 공간에서 연속적으로 움직이는 동안 모든 RGB-D 카메라에서 구의 깊이영상과 사진영상을 동시에 획득한다. 다음으로 각 RGB-D 카메라의 좌표계에서 획득한 구의 3차원 중심좌표를 월드좌표계에서 일치되도록 각 카메라의 외부변수를 보정한다.

• Journal of Computational Design and Engineering
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• 제1권4호
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• pp.272-288
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• 2014

This paper presents a two-step, semi-automated method for reconstructing a three-dimensional (3D) shape of the prostate from a 3D transrectal ultrasound (TRUS) image. While the method has been developed for prostate ultrasound imaging, it can potentially be applicable to any other organ of the body and other imaging modalities. The proposed method takes as input a 3D TRUS image and generates a watertight 3D surface model of the prostate. In the first step, the system lets the user visualize and navigate through the input volumetric image by displaying cross sectional views oriented in arbitrary directions. The user then draws partial/full contours on selected cross sectional views. In the second step, the method automatically generates a watertight 3D surface of the prostate by fitting a deformable spherical template to the set of user-specified contours. Since the method allows the user to select the best cross-sectional directions and draw only clearly recognizable partial or full contours, the user can avoid time-consuming and inaccurate guesswork on where prostate contours are located. By avoiding the usage of noisy, incomprehensible portions of the TRUS image, the proposed method yields more accurate prostate shapes than conventional methods that demand complete cross-sectional contours selected manually, or automatically using an image processing tool. Our experiments confirmed that a 3D watertight surface of the prostate can be generated within five minutes even from a volumetric image with a high level of speckles and shadow noises.

• 한국응용곤충학회지
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• 제48권1호
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• pp.45-51
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• 2009

본 연구의 목적은 쌀 저장창고에서 추출기를 이용하여 해충의 밀도를 추정하기 위한 축차추출법을 개발하는데 있다. 쌀 저장창고에서는 쌀을 주로 1톤의 톤백에 저장하는데, 현미로 저장되는 경우 어리쌀바구미 성충과 화랑곡나방 유충은 모두 부의 이항분포를 보였다. 축차추출법은 표본 추출 단위당 방제 시작 밀도를 0.1(현미 1 kg당 5마리), 비처리 밀도를 0.05(현미 1 kg당 2.5마리) 그리고 I($\alpha$), II형($\beta$) 오류를 0.3으로 설정하여 순차적 확률비 검정(sequential probability ratio test (SPRT))을 통해 개발하였다. 이러한 결과들은, SPRT법을 사용함으로써, 관리자들이 단지 20회의 표본 추출로도 잘못된 판단의 위험을 최소화하면서 의사결정을 할 수 있다는 것을 보여준다.