• Title/Summary/Keyword: Complete excision

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Complete genome sequence of Flavisolibacter tropicus LCS9T, a radiation resistant bacterium (방사선 내성 세균 Flavisolibacter tropicus LCS9T의 완전한 게놈 서열)

  • Kim, Myung Kyum;Sohn, Eun-Hwa;Jung, Hee-Young;Srinivasan, Sathiyaraj
    • Korean Journal of Microbiology
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    • v.54 no.1
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    • pp.87-89
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    • 2018
  • Flavisolibacter tropicus $LCS9^T$ was isolated from a soil sample collected from tropical zone within the Ecorium of the National Institute of Ecology in Seocheon, central-western Korea. In this study, we report the complete genome sequence of the bacterium Flavisolibacter tropicus $LCS9^T$, which possesses a circular chromosome comprised of 5, 940,863 bp with the G + C mol content of 41.5%. The genome sequence annotation showed that the complete genome includes 5,075 genes, 337 pseudogenes, and 59 rRNA genes. The radiation resistance genes such as excinuclease UvrABC complex and UvdE were present in the genome.

Benign Adenomyoepithelioma of the Breast: Imaging Characteristics (유방의 양성 선근상피세포종: 영상 특징)

  • So Ra Shin;Eun Young Ko;Boo-Kyung Han;Eun Sook Ko;Ji Soo Choi;Haejung Kim
    • Journal of the Korean Society of Radiology
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    • v.84 no.2
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    • pp.398-408
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    • 2023
  • Purpose This study aimed to evaluate the radiological and clinical characteristics of benign adenomyoepitheliomas of the breast. Materials and Methods Over the last 20 years, 120 patients were histologically diagnosed with breast adenomyoepithelioma (AME) at our institution. We excluded 43 patients who were incidentally diagnosed during mastectomy for breast cancer, 28 who underwent percutaneous biopsy without further excision, and 8 who had biopsy-confirmed benign AME and were found to have another pathology after complete excision. We retrospectively reviewed the clinical records and radiological findings of the remaining 41 patients with histologically diagnosed benign breast AMEs after complete excision. Results All 41 patients underwent US; 38 underwent mammography (MG) and US; and 18 underwent MG, US, and MRI. MG detected 38 cases with a round or oval shape (56%), and mass (89%), were non-circumscribed (62%), hyperdense (53%), and without microcalcifications (95%). Breast US revealed suspicious masses (98%) with a non-circumscribed margin (66%), hypoechogenicity (43%), and intratumoral vascularity (63%). All lesions on breast MRI showed suspicious masses (100%) with ill-defined margins (61%), and 84% showed wash-out kinetics. Benign AMEs showed suspicious features of Breast Imaging Reporting and Data System (BI-RADS) category 4 or 5 in 83%-95% of the MG, US, and MRI. Sixteen of the 41 cases were misdiagnosed on the initial core needle biopsy and two were diagnosed as malignancy. Conclusion Benign breast AME often shows suspicious radiological features mimicking a malignant mass on MG, US, and MRI. Differentiating benign AME from other pathologies might be difficult on core needle biopsy, and complete excision is needed for a correct diagnosis.

A Case of Pilomatrixoma after Split Thickness Skin Graft (식피술 후 발생한 모기질종 1례)

  • Choi, Jae Hoon;Park, Sung Gyu;Lee, Jin Hyo
    • Archives of Plastic Surgery
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    • v.33 no.6
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    • pp.753-756
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    • 2006
  • Purpose: Pilomatrixoma is a benign, usually asymptomatic tumor. It presents clinically as a solitary superficial subcutaneous nodule measuring between 0.5 cm and 5 cm in diameter on the head or upper extremeties and has not been reported after skin graft. The objective of this article is to report our experience in treating pilomatrixoma which occurred after split thickness skin graft on the lower extremity. Methods: A 56-year-old female was treated in August 2005 with a $0.5{\times}0.5cm$ firm subcutaneous nodule at recipient site of split thickness skin graft on the left medial thigh. The tumor was successfully removed by complete excision and histologic examination was followed. Results: The diagnosis was pilomatrixoma which was characterized by a dual population of proliferating basophilic cells and diagnostic shadow cells. Conclusion: The tumor was successfully treated by complete resection. The authors report this very rare case of pilomatrixoma which occurred at recipient site of split thickness skin graft.

Reconstruction of Lower Extremities using Anterolateral thigh Perforator Free Flaps (전외측 대퇴부 천공지 유리피판을 이용한 하지 재건)

  • Kim, Tae Gon;Kang, Min Gu
    • Journal of Trauma and Injury
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    • v.20 no.2
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    • pp.119-124
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    • 2007
  • Purpose: Management of the soft tissue defect in the lower extremity caused by trauma has always been difficult. Coverage with local and free muscle flaps after complete surgical excision of necrotic soft tissue and bone is a major strategy for treatment. There is no doubt that muscle provides a good blood supply, thus improving bone healing and increasing resistance to bacterial inoculation. However, accompanying problems are seen in cases with shallow dead space. This research was conducted to assess the efficacy of raising anterolateral thigh flaps and transferring them to the defect after complete debridement of non-viable, infected, and scar tissue as an alternative way to use local or free muscle flaps. Methods: From March 2005 to October 2007, 18 cases of soft tissue defect on lower extremities were re-surfaced with an anterolateral thigh perforator free flap. Results: The follow-up period ranged from 1 to 31 months with a mean of 15.9 months. All flaps survived completely. Satisfactory aesthetic and functional results were achieved. Under a two-point discrimination test, 13 patients had sensory recovery from 11 mm to 20 mm after 6 months postoperatively. Conclusion: Reconstruction of the lower extremity with anterolateral thigh perforator free flaps after appropriate debridement is a good alternative way to use local or free muscle flaps.

Chondrosarcoma of Thoracic Spine - A case report - (제 12 흉추체에 발생한 일차적 연골 육종 (증례 보고))

  • Rhee, Seung-Koo;Kim, Ki-Won;Kim, Jeong-Ho
    • The Journal of the Korean bone and joint tumor society
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    • v.3 no.2
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    • pp.131-136
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    • 1997
  • Although chondrosarcoma is a common primary malignant bone tumor, its occurrence in the spine is very rare. It is also well known that even after complete removal of chondrosarcoma in bone, not a few recurrence is possible. Surgical cure of a spinal chondrosarcoma is even more difficult because total excision of chondrosarcoma is usually impossible in the spine. No patients with spinal chondrosarcoma surviving more than 18 years has been reported in literature. We are reporting one patient(32 year old housewife) with chondrosarcoma at the $12^{th}$ thoracic spine which was treated with complete corpectomy of the $12^{th}$ thoracic vertebral body and rib and cancellous bone graft fixed with plating. She was followed for more than 3 years without local recurrence or distant metastasis.

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The Clinical Manifestations of Lipoblastoma in Children (소아 Lipoblastoma의 임상 양상)

  • Nam, So-Hyun;Kim, Dae-Yeon;Kim, Seong-Chul;Kim, In-Koo
    • Advances in pediatric surgery
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    • v.13 no.2
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    • pp.179-186
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    • 2007
  • Lipoblastoma is a rare benign soft tissue tumor occurring in infancy and early childhood. It is characterized by fat lobules with varying degrees of maturity, multivaculoated lipoblasts, fibrocapillary networks and myxoid stroma. Lipoblastoma has a good prognosis with no metastases despite its potential for local invasion. From Jan, 1990 through April, 2007, 12 children underwent the operation for lipoblastoma, 7 boys and 5 girls, diagnosed at median 22 months (5 ~ 43 months). Median follow up was 6 year 7 months. Primary sites included back (n = 5), intraabdominal (n = 2) and one in each of buttock, chest wall, neck, nose and scalp. Tumors presented with a growing mass in 9 patients, abdominal distension in 2, and an incidental finding on chest radiography in one. Complete excisions were done in all patients. There was one recurrence in a patient with a scalp mass. After reoperation, he has been doing well without evidence of recurrence. Lipoblastoma has a favorable prognosis, but recurrence can occur even with complete excision. Regular follow up is necessary to detect recurrences.

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Complete genome sequence of Spirosoma montaniterrae DY10T isolated from gamma-ray irradiated soil (감마선 조사된 토양에서 분리된 박테리아 Spirosoma montaniterrae DY10T 의 완전한 게놈 서열)

  • Srinivasan, Sathiyaraj;Kang, Myung-Suk;Kim, Myung Kyum
    • Korean Journal of Microbiology
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    • v.53 no.1
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    • pp.61-63
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    • 2017
  • A Gram-negative, yellow-pigmented, long-rod shaped bacterium Spirosoma montaniterrae $DY10^T$ was isolated from a soil sample collected at Mt. Deogyusan, Jeonbuk Province, Republic of Korea. Cells showed extreme gamma radiation resistance with the $D_{10}$ value of 12 KGy. The complete genome sequence of strain $DY10^T$ is consist of a circular chromosome (5,797,678 bp) encoding 5,116 genes, 9 rRNA genes and 39 tRNA genes. The genomic features contain the key enzymes for gamma and UVC radiation.

Gracilis pull-through flap for the repair of a recalcitrant recto-vaginal fistula

  • Mok, Wan Loong James;Goh, Ming Hui;Tang, Choong Leong;Tan, Bien Keem
    • Archives of Plastic Surgery
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    • v.46 no.3
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    • pp.277-281
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    • 2019
  • Recto-vaginal fistulas are difficult to treat due to their high recurrence rate. Currently, no single surgical intervention is universally regarded as the best treatment option for recto-vaginal fistulas. We present a case of recurrent recto-vaginal fistula surgically treated with a gracilis pull-through flap. The surgical goals in this patient were complete excision of the recto-vaginal fistula and introduction of fresh, vascularized muscle to seal the fistula. A defunctioning colostomy was performed 1 month prior to the present procedure. The gracilis muscle and tendon were mobilized, pulled through the freshened recto-vaginal fistula, passed through the anus, and anchored externally. Excess muscle and tendon were trimmed 1 week after the procedure. Follow-up at 4 weeks demonstrated complete mucosal coverage over an intact gracilis muscle, and no leakage. At 8 weeks post-procedure, the patient resumed sexual intercourse with no dyspareunia. At 6 months post-procedure, her stoma was closed. The patient reported transient fecal staining of her vagina after stoma reversal, which resolved with conservative treatment. The fistula had not recurred at 20 months post-procedure. The gracilis pull-through flap is a reliable technique for a scarred vagina with an attenuated recto-vaginal septum. It can function as a well-vascularized tissue plug to promote healing.

Preoperative chemoradiotherapy followed by local excision in clinical T2N0 rectal cancer

  • Shin, Young Seob;Yoon, Yong sik;Lim, Seok-Byung;Yu, Chang Sik;Kim, Tae Won;Chang, Heung Moon;Park, Jin-hong;Ahn, Seung Do;Lee, Sang-Wook;Choi, Eun Kyung;Kim, Jin Cheon;Kim, Jong Hoon
    • Radiation Oncology Journal
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    • v.34 no.3
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    • pp.177-185
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    • 2016
  • Purpose: To investigate whether preoperative chemoradiotherapy (PCRT) followed by local excision (LE) is feasible approach in clinical T2N0 rectal cancer patients. Materials and Methods: Patients who received PCRT and LE because of clinical T2 rectal cancer within 7 cm from anal verge between January 2006 and June 2014 were retrospectively analyzed. LE was performed in case of a good clinical response after PCRT. Patients' characteristics, treatment record, tumor recurrence, and treatment-related complications were reviewed at a median follow-up of 49 months. Results: All patients received transanal excision or transanal minimally invasive surgery. Of 34 patients, 19 patients (55.9%) presented pathologic complete response (pCR). The 3-year local recurrence-free survival and disease free-survival were 100.0% and 97.1%, respectively. There was no recurrence among the patients with pCR. Except for 1 case of grade 4 enterovesical fistula, all other late complications were mild and self-limiting. Conclusion: PCRT followed by an LE might be feasible as an alternative to total mesorectal excision in good responders with clinical T2N0 distal rectal cancer.

Subungual Exostosis of the Foot (족부의 조갑하 외골종)

  • Ahn, Jong-Chul;Shin, Duk-Seop;Shon, Oog-Jin;Choi, Joon-Hyuk
    • The Journal of the Korean bone and joint tumor society
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    • v.5 no.1
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    • pp.56-62
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    • 1999
  • Purpose : This study was conducted to analyze the clinical materials and treatment results of 13 cases of subungual exostosis. Materials and Methods : Thirteen subungual exostoses of the foot treated from January 1991 to December 1997 were studied. We analyzed the clinical data and results of treatment to identify the clinical characteristics of this disease. We investigated the location, shape and relation of exostosis to phalanx with simple x-ray of the foot to identify the radiological characteristics. All the cases were sent to pathologic examination after resection to determine the pathological characteristics. Results : The results of physical examination on presentation were various. Most cases were located at the dorsomedial side of the distal phalanx and were involved in the toe nail. Eleven cases were located at great toes and one each at the 2nd and 3rd toe. Causes of exostosis were not clear, but 2 cases were related to trauma. For the type of exostosis, 7 cases were sessile and 6 were stalk type. On histologic examination, 9 cases showed a cartilaginous portion with overlying proliferating fibrous tissue and underlying bone formation. There was a gradual maturation of spindle cell proliferation from cartilage to cancellous bone. The cartilage was moderately cellular with some pleomorphism, but true anaplasia was not present. Conclusion : The clinical presentation and findings of simple x-rays were most helpful in diagnosing subungual exostosis. Complete excision of the mass achieved complete relief of symptoms and recovery without recurrence in all cases.

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