• Tuberculosis and Respiratory Diseases
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• v.56 no.4
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• pp.393-404
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• 2004

Background : Nucleic acid hybridization has become an essential technique in the development of our understanding of gene structure and function. The quantitative analysis of hybridization has been used in the measurement of genome complexity and gene copy number. The filter hybridization assay is rapid, sensitive and can be used to measure RNAs complementary to any cloned DNA sequence. Methods : The authors assessed the accuracy, linearity, correlation coefficient and specificity of the hybridization depending on the added dose(0, 1, 5, and $10{\mu}g$) of non-specific rat spleen RNA to hybridization of surfactant protein A mRNA. Filter hybridization assays were used to obtain the equation of standard curve and thereby to quantitate the mRNA quantitation. Results : 1. Standard curve equation of filter hybridization assay between counts per minute (X) and spleen RNA input (Y) was Y=0.13X-19.35. Correlation coefficient was 0.98. 2. Standard curve equation of filter hybridization assay between counts per minute (X) and surfactant protein A mRNA transcript input (Y) was Y=0.00066X-0.046. Correlation coefficient was 0.99. 3. Standard curve equation of filter hybridization assay between counts per minute (X) and surfactant protein A mRNA transcript input (Y) after the addition of $1{\mu}g$ spleen RNA was Y=0.00056X-0.051. Correlation coefficient was 0.99. 4. Standard curve equation of filter hybridization assay between counts per minute (X) and surfactant protein A mRNA transcript input (Y) after the addition of $5{\mu}g$ spleen RNA was Y=0.00065X-0.088. Correlation coefficient was 0.99. 5. Standard curve equation of filter hybridization assay between counts per minute (X) and surfactant protein A mRNA transcript input (Y) after the addition of $10{\mu}g$ spleen RNA was Y=0.00051X-0.10. Correlation coefficient was 0.99. Conclusions : Comparison of cpm/filter in a linear range allowed accurate and reproducible estimation of surfactant protein A mRNA copy number irrespective of the addition dosage of non-specific rat spleen RNA over the range $0-10{\mu}g$.

• The Journal of the Acoustical Society of Korea
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• v.23 no.8
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• pp.570-575
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• 2004

In the underwater acoustic systems. we can receive signals and retrieve information about a target by using a beamforming method. The most important thing in the beamforming is finding the way to optimize the mainlobe beamwidth and the sidelobe level to the desired value. One of the prominent results of beamforming method. which has been studied. is Philip's weighting function method(1) . Philip's method adaptively adjusts its weights of array to meet the desired mainlobe beamwidth and sidelobe level. It is very similar to the design method in adaptive filter. However. this method cannot easily bring us to the desired sidelobe level due to complementary relation between mainlobe beamwidth and sidelobe level. In this paper, we propose a new algorithm using partial constrained adaptation. This method makes us circumvent the above problem and meet the specification of design easily. The proposed algorithm presents a Pattern synthesis that designer can easily control the mainlobe beamwidth and the sidelobe level to the desired value while calculation time to converge is decreasing.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.11
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• pp.1413-1420
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• 2018

The VR / AR market has grown significantly due to the development of virtual reality and augmented reality in the core technology field of the 4th Industrial Revolution. Since VR is basically focused on space and time, and the human brain is very sensitive to temporal events, it is important to make accurate I / O interface technology, one of the virtual reality technologies, not to affect the brain's cognitive ability. VR depends on the technology of the hardware such as the display and the sensor for biometric signal recognition. In this paper, in order to prevent the sensitive brain from affecting the sensor device in consideration of hardware dependency of VR, it is necessary to make various corrections to lower the motion to photon (MTP) to 20m / s or less experiments on the method and filtering were carried out.

• International Journal of Control, Automation, and Systems
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• v.3 no.4
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• pp.509-523
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• 2005

We are developing a novel framework, PRIDE (PRediction In Dynamic Environments), to perform moving object prediction (MOP) for autonomous ground vehicles. The underlying concept is based upon a multi-resolutional, hierarchical approach which incorporates multiple prediction algorithms into a single, unifying framework. The lower levels of the framework utilize estimation-theoretic short-term predictions while the upper levels utilize a probabilistic prediction approach based on situation recognition with an underlying cost model. The estimation-theoretic short-term prediction is via an extended Kalman filter-based algorithm using sensor data to predict the future location of moving objects with an associated confidence measure. The proposed estimation-theoretic approach does not incorporate a priori knowledge such as road networks and traffic signage and assumes uninfluenced constant trajectory and is thus suited for short-term prediction in both on-road and off-road driving. In this article, we analyze the complementary role played by vehicle kinematic models in such short-term prediction of moving objects. In particular, the importance of vehicle process models and their effect on predicting the positions and orientations of moving objects for autonomous ground vehicle navigation are examined. We present results using field data obtained from different autonomous ground vehicles operating in outdoor environments.

• Journal of information and communication convergence engineering
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• v.8 no.1
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• pp.51-58
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• 2010

This paper proposes an edge adaptive color interpolation for an ultra-small HD-grade complementary metal-oxide semiconductor (CMOS) video sensor in camera phones that can process 720-p/30-fps videos. Recently, proposed methods with great image quality perceptually reconstruct the green component and then estimate the red/blue component using the reconstructed green and neighbor red and blue pixels. However, these methods require the bulky memory line buffers in order to temporally store the reconstructed green components. The edge adaptive color interpolation method uses seven or nine patterns to calculate the six edge directions. At the same time, the threshold values are adaptively adjusted by the sum of the color values of the selected pixels. This method selects the suitable one among the patterns using two flowcharts proposed in this paper, and then interpolates the missing color values. For verification, we calculated the peak-signal-to-noise-ratio (PSNR) in the test images, which were processed by the proposed algorithm, and compared the calculated PSNR of the existing methods. The proposed color interpolation is also fabricated with the 0.18-${\mu}m$ CMOS flash memory process.

• Journal of Sensor Science and Technology
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• v.28 no.6
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• pp.345-354
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• 2019

The 3D position of pedestrians is a physical quantity used in various fields, such as automotive navigation and augmented reality. An inertial navigation system (INS) based pedestrian dead reckoning (PDR), hereafter INS-PDR, estimates the relative position of pedestrians using an inertial measurement unit (IMU). Since an INS-PDR integrates the accelerometer signal twice, cumulative errors occur and cause a rapid increase in drifts. Various correction methods have been proposed to reduce drifts. For example, one of the most commonly applied correction method is the zero velocity update (ZUPT). This study investigated the characteristics of the existing INS-PDR methods based on shoe-mounted IMU and compared the estimation performances under various conditions. Four methods were chosen: (i) altitude correction (AC); (ii) step length correction (SLC); (iii) advanced heuristic drift elimination (AHDE); and (iv) magnetometer-based heading correction (MHC). Experimental results reveal that each of the correction methods shows condition-sensitive performance, that is, each method performs better under the test conditions for which the method was developed than it does under other conditions. Nevertheless, AC and AHDE performed better than the SLC and MHC overall. The AC and AHDE methods were complementary to each other, and a combination of the two methods yields better estimation performance.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.10
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• pp.2129-2135
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• 2011

The WLAN and WPAN systems employed on 2.4GHz ISM band wireless networks provide complementary services within the same environments. Coexistence between the networks will be impaired, if the mutual packets are uncertainty associated the timing or gaussian distance. This paper analyzes the impact of the mutual interference on the services performance and in order to minimize the effect of WPAN system signals on the WLAN system, proposed a method of suppressing the interference on the WLAN system. The analysis is illustrated by examining the symbol error rate versus signal to noise interference ratio in terms of the carrier frequency offset.

• Journal of the Korean Society for Precision Engineering
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• v.26 no.11
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• pp.138-145
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• 2009

A suspended membrane micro fluidic heat flux sensor that is able to measure the heat flow rate was designed and fabricated by a complementary-metal-oxide-semiconductor-compatible process. The combination of a thirty-junction gold and nickel thermoelectric sensor with an ultralow noise preamplifier, low pass filter, and lock-in amp has enabled the resolution of 50 nW power and provides the sensitivity of $11.4\;mV/{\mu}W$. The heater modulation method was used to eliminate low frequency noises from sensor output. It is measured with various heat flux fluid of DI-water to test as micro fluidic application. In order to estimate the heat generation of samples from the output measurement of a micro fluidic heat-flux sensor, a methodology for modeling and simulating electro-thermal behavior in the micro fluidic heat-flux sensor with integrated electronic circuit is presented and validated. The electro-thermal model was constructed by using system dynamics, particularly the bond graph. The electro-thermal system model in which the thermal and the electrical domain are coupled expresses the heat generation of samples converts thermal input to electrical output. The proposed electro-thermal system model shows good agreement with measured output voltage response in transient state and steady-state.

• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2003.04a
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• pp.171-180
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• 2003

The merging of different scales or multi-sensor image data is becoming a widely used procedure of the complementary nature of various data sets. Ideally, the merging method should not distort the characteristics of the high-spatial and high-spectral resolution data used. To present an effective merging method for survey of reclaimed land, this paper compares the results of Intensity Hue Saturation (IHS), Principal Component Analysis (PCA), Color Normalized(CN) and High Pass Filter(HPF) methods used to merge the information contents of the high-resolution (6.6 m) Electro-Optical Camera (EOC) panchromatic image of the first Korea Multi-Purpose Satellite 1 (KOMPSAT-1) and the multi-spectral Moderate Resolution Imaging Spectroradiometer (MODIS) image data. The comparison is made by visual evaluation of three-color combination images of IHS, PCA, CN and HPF results based on spatial and spectral characteristics. The use of a contrasted EOC panchromatic image as a substitute for intensity in merged images with MODIS bands 1, 2 and 3 was found to be particularly effective in this study.

• Journal of electromagnetic engineering and science
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• v.9 no.1
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• pp.25-31
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• 2009

This paper describes CMOS VCO circuit design procedures and techniques for multi-band/multi-standard RF transceivers. The proposed techniques enable a 4 GHz CMOS VCO to satisfy all requirements for Quad-band GSMIEDGE and WCDMA standards by achieving a good trade-off among important specifications, phase noise, power consumption, modulation performance, and chip area efficiency. To meet the very stringent GSM T/Rx phase noise and wide frequency range specifications, the VCO utilizes bond-wire inductors with high-quality factor, an 8-bit coarse tune capbank for low VCO gain(30$\sim$50 MHz/V) and an on-chip $2^{nd}$ harmonic noise filter. The proposed VCO is implemented in $0.13{\mu}m$ CMOS technology. The measured tuning range is about 34 %(3.17 to 4.49 GHz). The VCO exhibits a phase noise of -123 dBc/Hz at 400 kHz offset and -145 dBc/Hz at 3 MHz offset from a 900 MHz carrier after LO chain. The calculated figure of merit(FOM) is -183.5 dBc/Hz at 3 MHz offset. This fully integrated VCO occupies $0.45{\times}0.9\;mm^2$.