• Proceedings of the Korea Association of Information Systems Conference
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• 2004.05a
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• pp.138-149
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• 2004

In this research we present a new model, PLCM(Cort-Logistics Chain Management), which can cooperate each other in the port-logistic industry that occupy a heavy rain in the Northeast Asian economy. PLCM(Port-Logistics Chain Management) synthetically manages the logistic chain and information laying stress on the port. Unlike SCM, which hat a vertical relationship between the main groups to cooperate each other, PLCM has a horizontal relationchip between the ports to achieve common purpose and to improve their whole competitive power. In this research we present a concept of PLCM and a specific plan to develop a system for PLCM targetting Pusan, Shanghai, and Tokyo Port which occupy a heavy rain in the Northeast Asian port industry. This system is composed of integrated information system and EDI document exchange system according to the special quality of user's request information. And in order to prove its feasibility and validity, the case study sailing from Shanghai to Busan has been applied to this study.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2004.10a
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• pp.397-400
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• 2004

The direct extrusion with porthole die can produce condenser tube which has the competitive power in costs and qualities compared with the existing conform extrusion. In general, porthole die extrusion has a great advantage in the forming that produces the hollow sections difficult to produce by conventional extrusion with a mandrel on the stem. Especially, condenser tube manufactured by porthole die belongs to sophisticated part and demands tighter dimension tolerance and higher surface finish than any other part. In order to confirm the general of porthole die extrusion, we perform the 3D FE analysis of hot porthole extrusion in non-steady state by using DEFORM 3D and investigate a pattern of elastic deformation for porthole die through the stress analysis using ANSYS 5.5 during extrusion process.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.23 no.11
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• pp.76-83
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• 2009

In today's competitive power market, electric power utilities have strived to provide energy at an acceptable level of quality due to increased expectations from customers. For this reason, electric power utilities have invested in electric equipment and new techniques. That is the Distribution Automation System (DAS). A merit of DAS is the ability to reduce outage time because of fast service restoration. However, DAS is usually installed in outdoor environments. Therefore, their efficiency is affected by the external conditions. Lightning creates varying degrees of physical stress on DAS. This paper focuses on the reliability of DAS for lightning. Four application studies were performed to compare the reliability indices.

• Korean Journal of Acupuncture
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• v.25 no.3
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• pp.167-174
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• 2008

Objective : To make comprehensive feature of previous researches on moxibustion, then build a basis of strategy for development of moxibustion-derived therapeutics. Methods : Surveyed 326 abstraction-containing literatures from total 467 of moxibustion-related papers in PubMed and 29 papers in Korea. Analysis was performed according to distribution by study subject, number by year, nation, research method, and its efficacy. Results : Moxibustion-related researches have been rapidly increased since 2001. The main contributive country for moxibustion research was China whileas few researches was done by Korea. The main subjects of moxibustion research are associated with immunity, inflammation, neurosystem, and digestive function. The most therapeutic roles of moxibustion were on pain control, modulation of immunity, anti-fatigue and anti-stress. Conclusion : This study will help Korean Oriental medical doctors to systematically review the moxibustion researches, and to develop more competitive therapeutics using moxibustion in global CAM field.

• Journal of Microbiology and Biotechnology
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• v.28 no.1
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• pp.40-49
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• 2018

We evaluated the antioxidant activity and neuronal cell-protective effect of fucoidan extract from Ecklonia cava (FEC) on hydrogen peroxide ($H_2O_2$)-induced cytotoxicity in PC-12 and MC-IXC cells to assess its protective effect against oxidative stress. Antioxidant activities were examined using the ABTS radical scavenging activity and malondialdehyde-inhibitory effect, and the results showed that FEC had significant antioxidant activity. Intracellular ROS contents and neuronal cell viability were investigated using the DCF-DA assay and MTT reduction assay. FEC also showed remarkable neuronal cell-protective effect compared with vitamin C as a positive control for both $H_2O_2$-treated PC-12 and MC-IXC cells. Based on the neuronal cell-protective effects, mitochondrial function was analyzed in PC-12 cells, and FEC significantly restored mitochondrial damage by increasing the mitochondrial membrane potential (${\Delta}{\Psi}m$) and ATP levels and regulating mitochondrial-mediated proteins (p-AMPK and BAX). Finally, the inhibitory effects against acetylcholinesterase (AChE), which is a critical hydrolyzing enzyme of the neurotransmitter acetylcholine in the cholinergic system, were investigated ($IC_{50}$ value = 1.3 mg/ml) and showed a mixed (competitive and noncompetitive) pattern of inhibition. Our findings suggest that FEC may be used as a potential material for alleviating oxidative stress-induced neuronal damage by regulating mitochondrial function and AChE inhibition.

• Journal of The Korea Institute of Healthcare Architecture
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• v.22 no.3
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• pp.7-15
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• 2016

Purpose: As medicare services have gotten spreaded, clinical laboratory has been dominant position. So, it has been acted for quality control and clinical pathology accreditation. But there has been quite deficient information to evaluate working space and technical standards of medical laboratory for accreditation. This study goals to figure out accreditation standard and design guideline for clinical laboratory, and to give safe and efficient design information. Methods: This study has been searched by literature for accreditation standards and design guidelines of clinical pathology in USA, UK, and Germany. Results: Three countries have accredited based on working lab space, staff space, storage space, patient space and health and safety equipment. Design guidelines of three countries commonly have focused on worktable layout, worktable distance and module, and specific laboratory biosafety level. And USA guidelines stress on the architectural design such as design process and passage distance for escape, UK stress on the efficiency as functional work flow and construction cost, lastly Germany design guidelines stress on the operator's safety distance and workstation. Three countries have not only accreditation standards but also design guidelines for more specific quality management, separating from accrediting institute. Implications: In korea, it has been needed to make clinical laboratory design guideline for the safe and efficient environment and reliable and competitive medical service.

• Tribology and Lubricants
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• v.37 no.2
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• pp.48-53
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• 2021

Wind energy is considered as the most competitive energy source in terms of power generation cost and efficiency. The power train of the pitch drive for a wind turbine uses a 3-stage complex planetary gear system in being developed locally. A gear train of the pitch drive consists of an electric or hydraulic motor and a planetary decelerator, which optimizes the pitch angle of the blade for wind generators in response to the change in wind speed. However, it is prone to many problems, such as excessive repair costs in case of failure. Complex planetary gears are very important parts of a pitch drive system because of strength problem. When gears are designed for the power train of a pitch drive, it is necessary to analyze the fatigue strength of gears. While calculating the specifications of the complex planetary gears along with the bending and compressive stresses of the gears, it is necessary to analyze the fatigue strength of gears to obtain an optimal design of the complex planetary gears in terms of cost and reliability. In this study, the specifications of planetary gears are calculated using a self-developed gear design program. The actual gear bending and compressive stresses of the planetary gear system were analyzed using the Lewes and Hertz equation. Additionally, the calculated specifications of the complex planetary gears were verified by evaluating the results from the Stress - No. of cycles curves of gears.

• Clinical and Experimental Pediatrics
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• v.45 no.9
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• pp.1106-1113
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• 2002

Purpose : Nuclear ($factor-{\kappa}BNF-{\kappa}B$) is now recognized as playing a potential role in programmed cell death and the adaptive response to various stress. Cellular hypoxia is a primary manifestation of many cardiovascular diseases. It seems that vascular endothelial growth factor (VEGF) and insulin like growth factor-I(IGF-I) have a function as a protective molecule in the heart against several stress including hypoxia. In this study, the role of $NF-{\kappa}B$ to the cellular response and regulation of protective molecules against the acute hypoxia in the heart was studied. Methods : To cause acute hypoxic stress to the heart, Sprague Dawley rats were exposed to hypoxic chamer($N_2$ 92% and $O_2$ 8%). After the hypoxic exposure, nuclear proteins, total proteins and mRNA were isolated from heart. Translocation of the transcription factors $NF-{\kappa}B$, NF-ATc, AP-1 and NKX-2.5 were evaluated by electrophoretic mobility shift assay(EMSA). The expression of IGF-I and VEGF were studied before and after the hypoxic stress by competitive-PCR, Northern hybridization and Western hybridization. To confirm the role of the $NF-{\kappa}B$ in the heart, the rats also were pretreated with diethyl-dithiocarbamic acid(DDTC) into peritoneal cavity to block $NF-{\kappa}B$ translocation into nucleus. Results : The expression of $NF-{\kappa}B$, AP-1 and NF-ATc were increased by the hypoxic stress. Increased expression of the VEGF and IGF-I were also observed by the hypoxic stress. However, the blocking of the $NF-{\kappa}B$ translocation reduced those expressions of VEGF and IGF-I. Conclusion : These results suggest that $NF-{\kappa}B$ has a protective role against the acute hypoxia through several gene expression, especially VEGF and IGF-I in heart muscle.

• Korean Institute of Interior Design Journal
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• v.21 no.3
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• pp.31-39
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• 2012

This is the time we need differentiated strategy due to consumer's standard of purchasing is becoming more complicated and corporate marketing war is intensely competitive. For a long-term strategy, making competitive corporate image is important because companies have their own competitiveness. In addition, importance of having a relationship with customer is magnified through consumers'direct and indirect experience. "The corporate complex cultural space is designed place for experiential marketing to convey its meaning to consumers." Under above concept, this study analyzed the theory of experiential marketing and conducted a survey which is based on experiential marketing strategic module (SEMs) using the analyzed theory. This study drew expression characteristics of space through case analysis and conducted a survey to have more effective corporate complex cultural space. As a result, the experience in the space enables people to understand of the space through five senses, not consist of simply chucks of sense-date, and this result emphasizes the importance of 'Event' because people tend to escape from restriction for reality to relive stress and have emotional satisfaction. In addition, it shows expression characteristics which provide sympathy as a flexible interaction through symbolical image. The result of the expression characteristics' survey is showed up to improve effect of corporate complex cultural space. This study is analyzing the corporate complex cultural space through experience marketing for the company which wants provide differentiated experience of various space expression methods and catching current position. Also, this study places its significance to give a way to increase space preference and effect of corporate complex cultural space. Based on the result of this study, I hope the future corporate complex cultural space will develop refreshingly.

• Journal of the Microelectronics and Packaging Society
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• v.16 no.2
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• pp.43-50
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• 2009

Although thin PCBs(Printed Circuit Boards) have recently been required for high density interconnection, high electrical performance, and low manufacturing cost, the utilization of thin PCBs is severely limited by warpage and reliability issues. Warpage of the thin PCB leads to failure in solder-joints and chip. The $B^2it$(Buried Bump Interconnection Technology) for PCB has been developed to achieve a competitive manufacturing price. In this study, chip temperature, package warpage, chip stress and solder-joints stress characteristics of the PCB prepared with $B^2it$ process have been calculated using thermo-mechanical coupled analysis by the FEM(Finite Element Method). FEM computation was carried out with the variations in bump shapes and kinds of materials under 1.5W power of chip and constant convection heat transfer. The results show that chip temperature distribution reached more quickly steady-state status with PCB prepared with $B^2it$ process than PCB prepared with conventional via interconnection structure. Although $B^2it$ structures are effective on low package warpage and chip stress, with high strength bump materials arc disadvantage for low stress of solder-joints. Therefore, it is recommended that optimized bump shapes and materials in PCB design should be considered in terms of reliability characteristics in the packaging level.